同步邏輯公司
US ˙ OTCPK ˙ US87166L2097

SecuritySYBX / Synlogic, Inc.
InstitutionVanguard Group Inc
Latest Disclosed Ownership201,060 shares
Latest Disclosed Value $ 225,187
Vanguard Group Inc reports 2.34% increase in ownership of SYBX / Synlogic, Inc.

On January 29, 2026 - Vanguard Group Inc filed a 13F-HR form disclosing ownership of 201,060 shares of Synlogic, Inc. (US:SYBX) valued at $225,187 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 7, 2025 disclosing 196,461 shares of Synlogic, Inc.. This represents a change in shares of 2.34% during the quarter. The current value of the position is $112,594 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F SYNLOGIC COM NEW 87166L209 201,060 4,599 2.34 225 -32.23 0.0000
2025-11-07 2025-09-30 13F SYNLOGIC COM NEW 87166L209 196,461 13,459 7.35 332 43.10 0.0000
2025-08-11 2025-06-30 13F SYNLOGIC COM NEW 87166L209 183,002 0 0.00 232 2.65 0.0000
2025-05-09 2025-03-31 13F SYNLOGIC COM NEW 87166L209 183,002 0 0.00 227 -9.60 0.0000
2025-02-11 2024-12-31 13F SYNLOGIC COM NEW 87166L209 183,002 0 0.00 251 -8.09 0.0000
2024-11-13 2024-09-30 13F SYNLOGIC COM NEW 87166L209 183,002 0 0.00 273 -0.73 0.0000
2024-08-13 2024-06-30 13F SYNLOGIC COM NEW 87166L209 183,002 0 0.00 275 -16.21 0.0000
2024-05-10 2024-03-31 13F SYNLOGIC COM NEW 87166L209 183,002 -5,431 -2.88 328 -54.90 0.0000
2024-03-11 2023-12-31 13F/A-1 SYNLOGIC COM NEW 87166L209 188,433 38,862 25.98 725 72.62 0.0000
2024-02-14 2023-12-31 13F SYNLOGIC COM NEW 87166L209 188,433 38,862 725 0.0000
2023-12-18 2023-09-30 13F/A-1 SYNLOGIC COM NEW 87166L209 149,571 -2,094,015 -93.33 420 -56.43 0.0000
2023-11-14 2023-09-30 13F SYNLOGIC COM NEW 87166L209 149,571 420
2023-08-14 2023-06-30 13F SYNLOGIC COM 87166L100 2,243,586 0 0.00 965 -31.97 0.0000
2023-07-14 2023-03-31 13F/A-1 SYNLOGIC COM 87166L100 2,243,586 0 0.00 1,418 -16.89 0.0000
2023-05-15 2023-03-31 13F SYNLOGIC COM 87166L100 2,243,586 0 1,418 0.0000
2023-02-10 2022-12-31 13F SYNLOGIC COM 87166L100 2,243,586 795 0.04 1,705 -19.95 0.0000
2022-11-14 2022-09-30 13F SYNLOGIC COM 87166L100 2,242,791 0 0.00 2,130 -17.44 0.0001
2022-08-12 2022-06-30 13F SYNLOGIC COM 87166L100 2,242,791 0 0.00 2,580 -52.07 0.0001
2022-05-13 2022-03-31 13F SYNLOGIC COM 87166L100 2,242,791 -9,209 -0.41 5,383 -1.21 0.0001
2022-02-14 2021-12-31 13F SYNLOGIC COM 87166L100 2,252,000 32,314 1.46 5,449 -19.51 0.0001
2021-11-12 2021-09-30 13F SYNLOGIC COM 87166L100 2,219,686 492,315 28.50 6,770 0.74 0.0002
2021-08-13 2021-06-30 13F SYNLOGIC COM 87166L100 1,727,371 888,009 105.80 6,720 123.55 0.0002
2021-05-14 2021-03-31 13F SYNLOGIC COM 87166L100 839,362 26,385 3.25 3,006 71.18 0.0001
2021-02-12 2020-12-31 13F SYNLOGIC COM 87166L100 812,977 31,941 4.09 1,756 11.28 0.0001
2020-11-16 2020-09-30 13F SYNLOGIC COM 87166L100 781,036 -70,144 -8.24 1,578 -8.68 0.0001
2020-08-14 2020-06-30 13F SYNLOGIC COM 87166L100 851,180 -34,967 -3.95 1,728 13.39 0.0001
2020-05-15 2020-03-31 13F SYNLOGIC COM 87166L100 886,147 1,144 0.13 1,524 -33.25 0.0001
2020-02-14 2019-12-31 13F SYNLOGIC COM 87166L100 885,003 -3,581 -0.40 2,283 12.19 0.0001
2019-11-14 2019-09-30 13F SYNLOGIC COM 87166L100 888,584 117,943 15.30 2,035 -70.98 0.0001
2019-08-14 2019-06-30 13F SYNLOGIC COM 87166L100 770,641 2,558 0.33 7,013 20.29 0.0003
2019-05-15 2019-03-31 13F SYNLOGIC COM 87166L100 768,083 39,581 5.43 5,830 14.16 0.0002
2019-02-14 2018-12-31 13F SYNLOGIC COM 87166L100 728,502 27,740 3.96 5,107 -48.71 0.0002
2018-12-13 2018-09-30 13F/A-2 SYNLOGIC COM 87166L100 700,762 47,591 7.29 9,958 55.11 0.0004
2018-11-23 2018-09-30 13F/A-1 SYNLOGIC COM 87166L100 700,762 0 9,958 0.0004
2018-11-14 2018-09-30 13F SYNLOGIC COM 87166L100 700,762 47,591 9,958
2018-08-14 2018-06-30 13F SYNLOGIC COM 87166L100 653,171 39,336 6.41 6,420 11.50 0.0003
2018-05-15 2018-03-31 13F SYNLOGIC COM 87166L100 613,835 515,391 523.54 5,758 502.93 0.0003
2018-02-14 2017-12-31 13F SYNLOGIC COM 87166L100 98,444 75,088 321.49 955 115.09 0.0000
2017-11-14 2017-09-30 13F SYNLOGIC COM 87166L100 23,356 23,356 444 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.