奧梅羅斯公司
US ˙ NasdaqGM ˙ US6821431029

SecurityOMER / Omeros Corporation
InstitutionBarclays Plc
Latest Disclosed Ownership120,490 shares
Latest Disclosed Value $ 2,069,416
Barclays Plc ownership in OMER / Omeros Corporation

On February 13, 2026 - Barclays Plc filed a 13F-HR form disclosing ownership of 120,490 shares of Omeros Corporation (US:OMER) valued at $2,069,416 USD as of December 31, 2025. The entity filed a previous 13F-HR/A on March 31, 2026 disclosing 131,948 shares of Omeros Corporation. This represents a change in shares of -8.68% during the quarter. The current value of the position is $1,235,022 USD.

Barclays Plc has a history of taking positions in derivatives of the underlying security (OMER) in the form of stock options. The firm currently holds call options representing 0 of underlying shares valued at $0 USD and put options representing 0 of underlying shares valued at $0 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

OMER / Omeros Corporation Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-13 2025-12-31 13F OMEROS COM 682143102 120,490 -11,458 -8.68 2,069 283.15 0.0005
2026-03-31 2025-09-30 13F/A-3 OMEROS COM 682143102 131,948 7,117 5.70 541 44.39 0.0001
2026-03-19 2025-09-30 13F/A-2 OMEROS COM 682143102 94,640 -30,191 376 0.0001
2025-11-12 2025-09-30 13F OMEROS COM 682143102 131,948 7,117 541 0.0001
2026-02-27 2025-06-30 13F/A-2 OMEROS COM 682143102 124,831 43,490 53.47 374 -44.01 0.0001
2025-08-14 2025-06-30 13F/A-1 OMEROS COM 682143102 124,831 43,490 0 0.0001
2025-08-13 2025-06-30 13F OMEROS COM 682143102 124,831 43,490 0 0.0000
2026-03-17 2025-03-31 13F/A-1 OMEROS COM 682143102 81,341 -22,385 -21.58 669 -34.77 0.0002
2025-05-15 2025-03-31 13F OMEROS COM 682143102 81,341 -22,385 1 0.0002
2026-03-19 2024-12-31 13F/A-1 OMEROS COM 682143102 103,726 9,086 9.60 1,025 173.07 0.0003
2025-02-13 2024-12-31 13F OMEROS COM 682143102 103,726 9,086 1 0.0003
2026-03-31 2024-09-30 13F/A-2 OMEROS COM 682143102 94,640 51,873 121.29 376 116.76 0.0001
2024-11-19 2024-09-30 13F/A-1 OMEROS COM 682143102 94,640 51,873 0 0.0001
2024-11-15 2024-09-30 13F OMEROS COM 682143102 94,640 51,873 0 0.0000
2026-03-23 2024-06-30 13F/A-1 OMEROS COM 682143102 42,767 -34,876 -44.92 174 -35.21 0.0001
2024-08-14 2024-06-30 13F OMEROS COM 682143102 42,767 -34,876 0 0.0001
2026-03-24 2024-03-31 13F/A-1 OMEROS COM 682143102 77,643 -40,824 -34.46 268 -31.01 0.0001
2024-05-15 2024-03-31 13F OMEROS COM 682143102 77,643 -40,824 0 0.0001
2026-03-25 2023-12-31 13F/A-1 OMEROS COM 682143102 118,467 72,838 159.63 387 190.98 0.0001
2024-02-15 2023-12-31 13F OMEROS COM 682143102 118,467 72,838 0 0.0001
2026-03-26 2023-09-30 13F/A-1 OMEROS COM 682143102 45,629 15,456 51.22 133 -18.90 0.0001
2023-11-07 2023-09-30 13F OMEROS COM 682143102 45,629 15,456 0 0.0001
2026-03-30 2023-06-30 13F/A-2 OMEROS COM 682143102 30,173 -50,233 -62.47 164 -56.03 0.0001
2023-09-20 2023-06-30 13F/A-1 OMEROS COM 682143102 30,173 -50,233 0 0.0001
2023-08-03 2023-06-30 13F OMEROS COM 682143102 30,173 -50,233 0 0.0001
2026-03-30 2023-03-31 13F/A-1 OMEROS COM 682143102 80,406 50,349 167.51 374 456.72 0.0002
2023-05-04 2023-03-31 13F OMEROS COM 682143102 80,406 50,349 0 0.0002
2026-03-30 2022-12-31 13F/A-1 OMEROS COM 682143102 30,057 26,445 732.14 68 509.09 0.0000
2023-02-13 2022-12-31 13F OMEROS COM 682143102 30,057 26,445 0 0.0000
2022-11-03 2022-09-30 13F OMEROS COM 682143102 3,612 -11,813 -76.58 11 -73.81 0.0000
2022-08-12 2022-06-30 13F OMEROS COM 682143102 15,425 -5,624 -26.72 42 -66.93 0.0000
2022-05-16 2022-03-31 13F OMEROS COM 682143102 21,049 -78,167 -78.78 127 -80.06 0.0001
2022-02-23 2021-12-31 13F/A-1 OMEROS COM 682143102 99,216 61,698 164.45 637 23.21 0.0002
2022-02-14 2021-12-31 13F OMEROS COM 682143102 99,216 61,698 637 0.0002
2021-11-09 2021-09-30 13F OMEROS COM 682143102 37,518 18,227 94.48 517 80.77 0.0002
2021-08-13 2021-06-30 13F OMEROS COM 682143102 19,291 -39,276 -67.06 286 -72.58 0.0001
2021-05-13 2021-03-31 13F OMEROS COM 682143102 58,567 34,174 140.10 1,043 198.85 0.0006
2021-02-11 2020-12-31 13F OMEROS COM 682143102 24,393 -19,528 -44.46 349 -21.40 0.0002
2020-11-12 2020-09-30 13F OMEROS COM 682143102 43,921 6,861 18.51 444 -18.68 0.0003
2020-08-12 2020-06-30 13F OMEROS COM 682143102 37,060 12,510 50.96 546 65.96 0.0004
2020-05-13 2020-03-31 13F OMEROS COM 682143102 24,550 -24,509 -49.96 329 -52.39 0.0003
2020-02-10 2019-12-31 13F OMEROS COM 682143102 49,059 -45,511 -48.12 691 -55.25 0.0004
2019-11-15 2019-09-30 13F/A-1 OMEROS COM 682143102 94,570 19,062 25.25 1,544 30.30 0.0010
2019-11-14 2019-09-30 13F OMEROS COM 682143102 94,570 19,062 1,544 356.9745
2019-08-14 2019-06-30 13F OMEROS COM 682143102 75,508 61,816 451.48 1,185 397.90 0.0007
2019-05-15 2019-03-31 13F OMEROS COM 682143102 13,692 13,416 4,860.87 238 7,833.33 0.0002
2019-02-14 2018-12-31 13F OMEROS COM 682143102 276 -44,926 -99.39 3 -99.73 0.0000
2018-11-14 2018-09-30 13F OMEROS COM 682143102 45,202 21,862 93.67 1,103 160.14 0.0008
2018-08-14 2018-06-30 13F OMEROS COM 682143102 23,340 1,048 4.70 424 70.97 0.0004
2018-05-15 2018-03-31 13F OMEROS COM 682143102 22,292 13,645 157.80 248 47.62 0.0002
2018-02-14 2017-12-31 13F OMEROS COM 682143102 8,647 2,733 46.21 168 31.25 0.0001
2017-11-14 2017-09-30 13F OMEROS COM 682143102 5,914 -2,687 -31.24 128 -25.58 0.0001
2017-08-14 2017-06-30 13F OMEROS COM 682143102 8,601 -1,004 -10.45 172 17.81 0.0002
2017-05-15 2017-03-31 13F OMEROS COM 682143102 9,605 -1,123 -10.47 146 35.19 0.0002
2017-02-14 2016-12-31 13F OMEROS COM 682143102 10,728 8,186 322.03 108 285.71 0.0001
2016-11-14 2016-09-30 13F OMEROS COM 682143102 2,542 2,011 378.72 28 460.00 0.0000
2016-08-12 2016-06-30 13F OMEROS COM 682143102 531 -316 -37.31 5 -58.33 0.0000
2016-05-16 2016-03-31 13F OMEROS COM 682143102 847 280 49.38 12 50.00 0.0000
2016-02-12 2015-12-31 13F OMEROS COM 682143102 567 -11,477 -95.29 8 -93.39 0.0000
2015-11-13 2015-09-30 13F OMEROS COM 682143102 12,044 7,162 146.70 121 45.78 0.0001
2015-08-14 2015-06-30 13F OMEROS COM 682143102 4,882 3,298 208.21 83 137.14 0.0001
2015-05-19 2015-03-31 13F/A-1 OMEROS COM 682143102 1,584 -15,672 -90.82 35 -91.53 0.0000
2015-05-14 2015-03-31 13F OMEROS COM 682143102 1,584 35
2015-02-13 2014-12-31 13F OMEROS COM 682143102 17,256 12,104 234.94 413 566.13 0.0004
2014-11-14 2014-09-30 13F OMEROS COM 682143102 5,152 -3,328 -39.25 62 -56.64 0.0001
2014-08-14 2014-06-30 13F OMEROS COM 682143102 8,480 1,182 16.20 143 62.50 0.0002
2014-05-15 2014-03-31 13F OMEROS COM 682143102 7,298 5,522 310.92 88 340.00 0.0001
2014-02-13 2013-12-31 13F OMEROS COM 682143102 1,776 -24 -1.33 20 25.00 0.0000
2013-11-14 2013-09-30 13F OMEROS COM 682143102 1,800 -1,010 -35.94 16 14.29 0.0000
2013-08-14 2013-06-30 13F OMEROS COM 682143102 2,810 2,810 14 0.0000
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2020-05-13 2020-03-31 13F OMEROS OPT Call 0 -100.00 0 -100.00 n/a n/a n/a
2020-02-10 2019-12-31 13F OMEROS OPT Call 1,800 -10.00 25 -24.24 n/a n/a n/a
2019-11-15 2019-09-30 13F/A OMEROS OPT Call 2,000 -9.09 33 -5.71 n/a n/a n/a
2019-11-14 2019-09-30 13F OMEROS OPT Call 2,000 33 n/a n/a n/a
2019-08-14 2019-06-30 13F OMEROS OPT Call 2,200 -81.97 35 -83.49 n/a n/a n/a
2019-05-15 2019-03-31 13F OMEROS OPT Call 12,200 46.99 212 130.43 n/a n/a n/a
2019-02-14 2018-12-31 13F OMEROS OPT Call 8,300 92 n/a n/a n/a
2018-11-14 2018-09-30 13F OMEROS OPT Call 0 -100.00 0 -100.00 n/a n/a n/a
2018-08-14 2018-06-30 13F OMEROS OPT Call 600 -92.86 11 -88.30 n/a n/a n/a
2018-05-15 2018-03-31 13F OMEROS OPT Call 8,400 600.00 94 308.70 n/a n/a n/a
2018-02-14 2017-12-31 13F OMEROS OPT Call 1,200 500.00 23 475.00 n/a n/a n/a
2017-11-14 2017-09-30 13F OMEROS OPT Call 200 0.00 4 0.00 n/a n/a n/a
2017-08-14 2017-06-30 13F OMEROS OPT Call 200 0.00 4 33.33 n/a n/a n/a
2017-05-15 2017-03-31 13F OMEROS OPT Call 200 3 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2020-08-12 2020-06-30 13F OMEROS OPT Put 0 -100.00 0 -100.00 n/a n/a n/a
2020-05-13 2020-03-31 13F OMEROS OPT Put 1,000 0.00 13 -7.14 n/a n/a n/a
2020-02-10 2019-12-31 13F OMEROS OPT Put 1,000 14 n/a n/a n/a
2019-05-15 2019-03-31 13F OMEROS OPT Put 0 -100.00 0 -100.00 n/a n/a n/a
2019-02-14 2018-12-31 13F OMEROS OPT Put 600 0.00 7 -53.33 n/a n/a n/a
2018-11-14 2018-09-30 13F OMEROS OPT Put 600 -45.45 15 -25.00 n/a n/a n/a
2018-08-14 2018-06-30 13F OMEROS OPT Put 1,100 -38.89 20 0.00 n/a n/a n/a
2018-05-15 2018-03-31 13F OMEROS OPT Put 1,800 20 n/a n/a n/a
2017-11-14 2017-09-30 13F OMEROS OPT Put 0 -100.00 0 -100.00 n/a n/a n/a
2017-08-14 2017-06-30 13F OMEROS OPT Put 4,000 -97.80 80 -97.08 n/a n/a n/a
2017-05-15 2017-03-31 13F OMEROS OPT Put 181,500 2,744 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.