伊奧尼斯製藥公司
MX ˙ BMV ˙ US4622221004
SecurityMX:IONS / Ionis Pharmaceuticals, Inc.
InstitutionCI Private Wealth, LLC
Latest Disclosed Ownership196,599 shares
Latest Disclosed Value $ 14,762,623
CI Private Wealth, LLC reports 9.17% decrease in ownership of IONS / Ionis Pharmaceuticals, Inc.

On May 15, 2026 - CI Private Wealth, LLC filed a 13F-HR form disclosing ownership of 196,599 shares of Ionis Pharmaceuticals, Inc. (MX:IONS) valued at $14,762,623 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on March 9, 2026 disclosing 216,438 shares of Ionis Pharmaceuticals, Inc.. This represents a change in shares of -9.17% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F IONIS PHARMACEUTICALS COM 462222100 196,599 -19,839 -9.17 14,763 -13.78 0.0206
2026-03-09 2025-12-31 13F/A-1 IONIS PHARMACEUTICALS COM 462222100 216,438 209,848 3,184.34 17,122 3,872.62 0.0233
2026-02-19 2025-12-31 13F IONIS PHARMACEUTICALS COM 462222100 214,936 208,346 17,004 0.0064
2025-11-14 2025-09-30 13F IONIS PHARMACEUTICALS COM 462222100 6,590 -231,250 -97.23 431 -95.41 0.0007
2025-09-26 2025-06-30 13F/A-1 IONIS PHARMACEUTICALS COM 462222100 237,840 707 0.30 9,397 31.35 0.0125
2025-08-15 2025-06-30 13F IONIS PHARMACEUTICALS COM 462222100 237,931 798 9,401 0.0099
2025-05-14 2025-03-31 13F IONIS PHARMACEUTICALS COM 462222100 237,133 -2,030 -0.85 7,154 -14.44 0.0117
2025-02-10 2024-12-31 13F IONIS PHARMACEUTICALS COM 462222100 239,163 2,087 0.88 8,361 -11.96 0.0139
2024-11-12 2024-09-30 13F IONIS PHARMACEUTICALS COM 462222100 237,076 -30,961 -11.55 9,497 -25.65 0.0148
2024-08-13 2024-06-30 13F IONIS PHARMACEUTICALS COM 462222100 268,037 746 0.28 12,775 10.24 0.0223
2024-05-09 2024-03-31 13F IONIS PHARMACEUTICALS COM 462222100 267,291 -21 -0.01 11,587 -14.32 0.0206
2024-02-09 2023-12-31 13F IONIS PHARMACEUTICALS COM 462222100 267,312 -39,678 -12.92 13,523 -2.89 0.0249
2023-11-03 2023-09-30 13F IONIS PHARMACEUTICALS COM 462222100 306,990 1,522 0.50 13,925 11.11 0.0320
2023-08-10 2023-06-30 13F IONIS PHARMACEUTICALS COM 462222100 305,468 182 0.06 12,533 14.88 0.0289
2023-05-15 2023-03-31 13F IONIS PHARMACEUTICALS COM 462222100 305,286 2,609 0.86 10,911 -4.57 0.0293
2023-02-15 2022-12-31 13F IONIS PHARMACEUTICALS COM 462222100 302,677 302,677 11,432 0.0415
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.