| 已發行股份 | 36,597,334 shares |
| 內部人士股份 | 2,269,075 shares |
| 內部持股 | 6.20 % |
內部人士情緒分數
「內部人士情緒分數」用於查找被公司內部人士購入的公司。
它是一個複雜的多因素量化模型的結果，該模型能夠辨識具有最高內部人士累積持有水平的公司。該評分模型結合了內部人士在過去90天內購買的淨數量、總購買股份佔流通股比例，以及內部人士擁有的總股份的指標。該分數的範圍從0到100，數值越高表示相對於同行業而言具有更高程度的內部人士持股水平，50為平均值。
更新頻率：每日
高管情緒分數
「高管情緒分數」用於查找被公司管理層購入的公司。
根據定義，公司高管是公司內部人士，但與其他內部人士（10%的股東和董事會成員）不同，公司高管每天在公司工作，而且他們使用自己的資金進行交易。（10%的股東和董事會成員通常是基金經理，管理著其他人的資金。）因此，公司高管進行的內幕交易更為重要性，應該被適當地重視和關注。
如同「內部人士情緒分數」，「高管情緒分數」也是一個複雜的多因素量化模型的計算結果，該模型能夠辨識具有最高高管累積持有水平的公司。
更新頻率：每日
關鍵內部人士指標
此表格顯示了公司在各種內部人士指標上的排名。百分位數排名顯示了這家公司在美國市場與其他公司相比的表現。排名越高表明公司所處狀況越好。
舉例來說，一般認為內部人士的買入是一個積極的指標，因此具有更多內部人士買入的公司將排名高於那些內部人士買入較少（甚至有內部人士賣出）的公司。
內部人士買入淨數（排名）
N/A
內部人士買入淨數是過去90天內買入的內部人士總數減去賣出的內部人士總數。以百分位排名顯示（範圍從0到100%）。
內部人士買入佔流通股比例（排名）
N/A
內部人士買入佔流通股比例是內部人士在過去90天內購買的股份總數減去賣出的股份總數，除以總流通股數並乘以100。
內幕交易圖表
以下圖表顯示了BIOLASE, Inc.內部人士交易。內部人士包括公司的高管、董事或重要投資者。一般而言，基於內幕、非公開信息進行交易是非法的。這並不意味著他們在自己的公司進行任何交易都是非法的。但是，他們必須透過Form 4向美國證券交易委員會（SEC）報告所有交易。
內部人員名單及盈利指標
這張表格顯示已知的內部人員名單，從向SEC披露的申報文件中自動生成。除了姓名、最近的職稱和董事、高管或10%擁有人的標誌外，我們還提供了最新披露的持股信息。此外，我們盡可能提供內部人的歷史交易表現。歷史交易表現是內部人士實際進行的公開市場購買交易表現的加權平均值。有關此計算方式的更多資訊，請查看YouTube網絡研討會。
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| 內部人士 | 平均收益（%） | 持股 數量 |
分拆 調整 |
|---|
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追蹤內部人士買入記錄 - 短期收益分析
在這一部分，我們分析了在 BIOL / BIOLASE, Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況， 結果僅為理論值。 .
以下表格顯示了最近的自動交易計劃之外的公開市場購買。
經調整價格 已按拆股調整。 經調整股數 已按拆股調整。
追蹤內部人士賣出記錄 - 短期虧損分析
在這一部分，我們分析了在 BIOL / BIOLASE, Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況， 結果僅為理論值。 .
以下表格顯示了最近的自動交易計劃之外的公開市場購買。
經調整價格 已按拆股調整。 經調整股數 已按拆股調整。
交易歷史
點擊連結圖示即可查看完整的交易記錄。作為 10b5-1 自動交易計畫的一部分進行報告的交易，將在標記為 10b-5 的欄位中顯示 X。
| 呈報 日期 |
交易 日期 |
表格 | 內部人士 | 證券代碼 | 證券種類 | 代碼 | 直接 | 行使 價格 |
單位 價格 |
股數 變化 |
價值 變化 (1K) |
剩餘 期權 |
剩餘 股份 |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2023-10-06 | 3 | GOLDMAN SACHS GROUP INC | BIOL | Common Stock | I | 144,501 | ||||||||
| 2023-05-26 | 2020-12-18 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.2800 | -187,774 | -53 | 5,522,223 | ||||
| 2023-05-26 | 2020-12-17 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.2800 | -572,671 | -160 | 5,709,997 | ||||
| 2023-05-26 | 2020-12-16 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.2800 | -90,575 | -25 | 6,282,668 | ||||
| 2023-05-26 | 2020-12-04 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.3000 | -1,200,000 | -360 | 6,373,243 | ||||
| 2023-05-26 | 2020-11-30 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.3000 | -1,115,000 | -334 | 7,573,243 | ||||
| 2023-05-26 | 2020-11-25 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.2900 | -203,057 | -59 | 8,688,243 | ||||
| 2023-05-26 | 2020-11-24 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.3000 | -71,100 | -21 | 8,891,300 | ||||
| 2023-05-26 | 2020-07-28 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.4000 | 3,745,000 | 1,498 | 8,962,400 | ||||
| 2023-05-26 | 2020-06-10 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.5500 | -1,733,836 | -954 | 5,217,400 | ||||
| 2023-05-26 | 2020-06-09 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.5400 | -2,137,559 | -1,154 | 6,951,236 | ||||
| 2023-05-26 | 2020-06-08 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.5500 | -1,847,649 | -1,016 | 9,088,795 | ||||
| 2023-05-26 | 2020-02-11 | 4 | Schuler Family Foundation | BIOL | Common Stock | D | 0.6100 | 1,307,931 | 798 | 10,936,444 | ||||
| 2022-12-08 | 2022-12-07 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 0.7500 | -3,537 | -3 | 59,925 | ||||
| 2022-07-14 | 3 | Sandor Steven | BIOL | Common Stock | D | 2,355 | ||||||||
| 2022-07-14 | 3 | Bright Jennifer | BIOL | Common Stock | D | 160 | ||||||||
| 2022-05-13 | 2022-05-11 | 4 | Yale Kenneth P. | BIOL | Restricted Stock | D | 3,200 | 44,127 | ||||||
| 2022-05-13 | 2022-05-11 | 4 | Yale Kenneth P. | BIOL | Restricted Stock Unit | D | 40,927 | 40,927 | ||||||
| 2022-05-13 | 2022-05-11 | 4 | Summerhays Carol Gomez DDS | BIOL | Restricted Stock Unit | D | 40,078 | 40,078 | ||||||
| 2022-05-13 | 2022-05-11 | 4 | Somerman Martha J. DDS, PhD | BIOL | Restricted Stock Unit | D | 42,232 | 42,232 | ||||||
| 2022-05-13 | 2022-05-11 | 4 | ROPER JESS | BIOL | Restricted Stock Unit | D | 41,775 | 41,775 | ||||||
| 2022-05-13 | 2022-05-11 | 4 | OLoughlin Kathleen T | BIOL | Restricted Stock Unit | D | 40,927 | 40,927 | ||||||
| 2022-05-12 | 2022-05-11 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 58,747 | 58,747 | ||||||
| 2022-05-02 | 2022-04-28 | 4 | LORD JONATHAN T MD | BIOL | Series G Preferred Stock | D | -1,395 | 0 | ||||||
| 2022-05-02 | 2022-04-28 | 4 | ROPER JESS | BIOL | Series G Preferred Stock | D | -346 | 0 | ||||||
| 2022-05-02 | 2022-04-28 | 4 | BEAVER JOHN R | BIOL | Series G Preferred Stock | D | -555 | 0 | ||||||
| 2022-02-10 | 2022-02-08 | 4 | Somerman Martha J. DDS, PhD | BIOL | Restricted Stock Unit | D | 90,000 | 90,000 | ||||||
| 2022-02-10 | 2022-02-08 | 4 | Summerhays Carol Gomez DDS | BIOL | Restricted Stock Unit | D | 90,000 | 90,000 | ||||||
| 2022-02-10 | 2022-02-08 | 4 | OLoughlin Kathleen T | BIOL | Restricted Stock Unit | D | 90,000 | 90,000 | ||||||
| 2021-12-16 | 2021-12-15 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 0.3800 | -11,038 | -4 | 633,096 | ||||
| 2021-12-02 | 2021-11-30 | 4 | BEAVER JOHN R | BIOL | Common Stock | D | 0.4500 | 70,000 | 32 | 621,530 | ||||
| 2021-08-26 | 2021-08-12 | 4 | OLoughlin Kathleen T | BIOL | Stock Appreciation Right | D | 0.63 | 98,955 | 98,955 | |||||
| 2021-08-23 | 2021-08-12 | 4 | Somerman Martha J. DDS, PhD | BIOL | Stock Appreciation Right | D | 0.63 | 98,955 | 98,955 | |||||
| 2021-08-23 | 2021-08-12 | 4 | Summerhays Carol Gomez DDS | BIOL | Stock Appreciation Right | D | 0.63 | 98,955 | 98,955 | |||||
| 2021-08-23 | 2021-08-20 | 4 | BEAVER JOHN R | BIOL | Common Stock | D | 0.6100 | 35,000 | 21 | 551,530 | ||||
| 2021-08-13 | 2021-08-11 | 4 | BEAVER JOHN R | BIOL | Stock Appreciation Right | D | 0.63 | 220,000 | 220,000 | |||||
| 2021-06-14 | 2021-06-11 | 4 | BEAVER JOHN R | BIOL | Restricted Stock Unit | D | 4,144,139 | 4,144,139 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | DiTolla Michael | BIOL | Restricted Stock Unit | D | 110,400 | 110,400 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | DiTolla Michael | BIOL | Stock Appreciation Right | D | 0.84 | 104,603 | 104,603 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Wagner Elaine C | BIOL | Restricted Stock Unit | D | 138,000 | 138,000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | Wagner Elaine C | BIOL | Stock Appreciation Right | D | 0.84 | 104,603 | 104,603 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Lanman Richard B. | BIOL | Restricted Stock Unit | D | 138,000 | 138,000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | Lanman Richard B. | BIOL | Stock Appreciation Right | D | 0.84 | 104,603 | 104,603 | |||||
| 2021-06-14 | 2021-06-11 | 4 | Sato Garrett | BIOL | Restricted Stock Unit | D | 138,000 | 138,000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | Sato Garrett | BIOL | Stock Appreciation Right | D | 0.84 | 110,888 | 110,888 | |||||
| 2021-06-14 | 2021-06-11 | 4 | ROPER JESS | BIOL | Restricted Stock Unit | D | 138,000 | 138,000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | ROPER JESS | BIOL | Stock Appreciation Right | D | 0.84 | 111,337 | 111,337 | |||||
| 2021-06-14 | 2021-06-11 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 330,000 | 330,000 | ||||||
| 2021-06-14 | 2021-06-11 | 4 | LORD JONATHAN T MD | BIOL | Stock Appreciation Right | D | 0.84 | 189,902 | 189,902 | |||||
| 2021-05-19 | 2021-05-19 | 4 | BEAVER JOHN R | BIOL | Common Stock | D | 0.7500 | 40,000 | 30 | 516,530 | ||||
| 2021-03-26 | 2021-03-24 | 4 | BEAVER JOHN R | BIOL | Restricted Stock Unit | D | 100,000 | 350,692 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | BEAVER JOHN R | BIOL | Restricted Stock Unit | D | 200,000 | 250,692 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | Norbe Todd | BIOL | Restricted Stock Unit | D | 200,000 | 833,333 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 20,000 | 443,602 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | ROPER JESS | BIOL | Restricted Stock Unit | D | 20,000 | 260,397 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | Sato Garrett | BIOL | Restricted Stock Unit | D | 20,000 | 245,856 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | Wagner Elaine C | BIOL | Restricted Stock Unit | D | 20,000 | 245,856 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | DiTolla Michael | BIOL | Restricted Stock Unit | D | 20,000 | 273,988 | ||||||
| 2020-08-10 | 2020-08-06 | 4 | Lanman Richard B. | BIOL | Restricted Stock Unit | D | 20,000 | 245,856 | ||||||
| 2020-07-23 | 2020-07-22 | 4 | LORD JONATHAN T MD | BIOL | Series F Convertible Preferred | D | 0.40 | 6 | 6 | |||||
| 2020-07-23 | 2020-07-22 | 4 | LORD JONATHAN T MD | BIOL | Warrants | D | 0.40 | 15,000 | 15,000 | |||||
| 2020-07-23 | 2020-07-22 | 4 | Norbe Todd | BIOL | Series F Convertible Preferred | D | 0.40 | 3 | 3 | |||||
| 2020-07-23 | 2020-07-22 | 4 | Norbe Todd | BIOL | Warrants | D | 0.40 | 7,500 | 7,500 | |||||
| 2020-07-23 | 2020-07-22 | 4 | BEAVER JOHN R | BIOL | Series F Convertible Preferred | D | 0.40 | 7 | 7 | |||||
| 2020-07-23 | 2020-07-22 | 4 | BEAVER JOHN R | BIOL | Warrants | D | 0.40 | 17,500 | 17,500 | |||||
| 2020-06-10 | 2020-06-09 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5508 | -10,400 | -6 | 0 | ||||
| 2020-06-10 | 2020-06-09 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5486 | -47,885 | -26 | 0 | ||||
| 2020-06-10 | 2020-06-09 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5514 | -79,841 | -44 | 184,300 | ||||
| 2020-06-10 | 2020-06-09 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5514 | -435,596 | -240 | 278,300 | ||||
| 2020-06-10 | 2020-06-09 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5514 | -1,196,590 | -660 | 1,276,500 | ||||
| 2020-06-10 | 2020-06-08 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5542 | -358,744 | -199 | 264,141 | ||||
| 2020-06-10 | 2020-06-08 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.5542 | -564,738 | -313 | 713,896 | ||||
| 2020-06-10 | 2020-06-08 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share ("Common Stock") | I | 0.5542 | -2,479,456 | -1,374 | 2,473,090 | ||||
| 2020-05-28 | 2020-05-13 | 4 | ROPER JESS | BIOL | Stock Option (right to buy) | D | 0.38 | 187,378 | 187,378 | |||||
| 2020-05-28 | 2020-05-13 | 4 | ROPER JESS | BIOL | Restricted Stock Unit | D | 165,245 | 240,397 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | Lanman Richard B. | BIOL | Stock Option (right to buy) | D | 0.38 | 176,045 | 205,084 | |||||
| 2020-05-28 | 2020-05-13 | 4 | Lanman Richard B. | BIOL | Restricted Stock Unit | D | 155,250 | 225,856 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | DiTolla Michael | BIOL | Stock Option (right to buy) | D | 0.38 | 176,045 | 176,045 | |||||
| 2020-05-28 | 2020-05-13 | 4 | DiTolla Michael | BIOL | Restricted Stock Unit | D | 155,250 | 253,988 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | Sato Garrett | BIOL | Stock Option (right to buy) | D | 0.38 | 176,045 | 184,880 | |||||
| 2020-05-28 | 2020-05-13 | 4 | Sato Garrett | BIOL | Restricted Stock Unit | D | 155,250 | 225,856 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | Wagner Elaine C | BIOL | Stock Option (right to buy) | D | 0.38 | 176,045 | 176,045 | |||||
| 2020-05-28 | 2020-05-13 | 4 | Wagner Elaine C | BIOL | Restricted Stock Unit | D | 155,250 | 225,856 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | BEAVER JOHN R | BIOL | Restricted Stock Unit | D | 11,246 | 50,692 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | Norbe Todd | BIOL | Restricted Stock Unit | D | 30,450 | 80,450 | ||||||
| 2020-05-28 | 2020-05-13 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 0.38 | 330,178 | 443,659 | |||||
| 2020-05-28 | 2020-05-13 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 291,178 | 423,602 | ||||||
| 2020-05-15 | 2020-02-11 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.6000 | -1,307,931 | -785 | 739,820 | ||||
| 2019-11-22 | 2019-11-14 | 4 | DiTolla Michael | BIOL | Restricted Stock Unit | D | 98,738 | 98,738 | ||||||
| 2019-10-31 | 2019-10-29 | 4 | FEINBERG LARRY N | BIOL | Series E Preferred Stock | I | 57.5000 | 1,843 | 106 | 1,843 | ||||
| 2019-10-31 | 2019-10-29 | 4 | FEINBERG LARRY N | BIOL | Series E Preferred Stock | I | 57.5000 | 2,783 | 160 | 2,783 | ||||
| 2019-10-31 | 2019-10-29 | 4 | FEINBERG LARRY N | BIOL | Series E Preferred Stock | I | 57.5000 | 12,765 | 734 | 12,765 | ||||
| 2019-08-27 | 2019-08-23 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2200 | -216 | -0 | 109,124 | ||||
| 2019-08-27 | 2019-08-23 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2000 | -2,687 | -3 | 109,340 | ||||
| 2019-08-22 | 2019-08-22 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2200 | -57 | -0 | 112,027 | ||||
| 2019-08-22 | 2019-08-22 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2200 | -8,045 | -10 | 112,084 | ||||
| 2019-08-22 | 2019-08-21 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2000 | -4,800 | -6 | 120,129 | ||||
| 2019-08-22 | 2019-08-21 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2200 | -643 | -1 | 124,929 | ||||
| 2019-08-22 | 2019-08-20 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2200 | -12,605 | -15 | 125,572 | ||||
| 2019-08-19 | 2019-08-19 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2200 | -4,323 | -5 | 138,177 | ||||
| 2019-08-19 | 2019-08-16 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.2500 | -37 | -0 | 142,500 | ||||
| 2019-08-19 | 2019-08-15 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.3000 | -7,715 | -10 | 142,537 | ||||
| 2019-08-09 | 2019-08-07 | 4 | Norbe Todd | BIOL | Restricted Stock Unit | D | 100,000 | 633,333 | ||||||
| 2019-08-09 | 2019-08-07 | 4 | BEAVER JOHN R | BIOL | Restricted Stock Unit | D | 70,000 | 128,267 | ||||||
| 2019-08-09 | 2019-08-07 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 132,424 | 709,569 | ||||||
| 2019-08-09 | 2019-08-07 | 4 | ROPER JESS | BIOL | Restricted Stock Unit | D | 75,152 | 158,485 | ||||||
| 2019-08-09 | 2019-08-07 | 4 | Lanman Richard B. | BIOL | Restricted Stock Unit | D | 70,606 | 151,640 | ||||||
| 2019-08-09 | 2019-08-07 | 4 | Sato Garrett | BIOL | Restricted Stock Unit | D | 70,606 | 151,640 | ||||||
| 2019-08-09 | 2019-08-07 | 4 | Wagner Elaine C | BIOL | Restricted Stock Unit | D | 70,606 | 114,980 | ||||||
| 2019-06-27 | 2019-06-25 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.5000 | -227,155 | -341 | 438,585 | ||||
| 2019-06-27 | 2019-06-25 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.5000 | -263,845 | -396 | 1,000,334 | ||||
| 2019-06-27 | 2019-06-25 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share ("Common Stock") | I | 1.5000 | -509,000 | -764 | 3,676,046 | ||||
| 2019-06-05 | 2019-06-04 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.6000 | -948 | -2 | 33,585 | ||||
| 2019-06-05 | 2019-06-03 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.5200 | -4,446 | -7 | 34,533 | ||||
| 2019-06-03 | 2019-05-31 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.5500 | -30,094 | -47 | 38,979 | ||||
| 2019-06-03 | 2019-05-30 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.7800 | -17,594 | -31 | 69,073 | ||||
| 2018-12-14 | 2018-12-13 | 4 | Sato Garrett | BIOL | Common Stock | D | 1.0700 | 5,000 | 5 | 15,000 | ||||
| 2018-12-14 | 2018-12-13 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.0200 | 2,200 | 2 | 15,000 | ||||
| 2018-12-14 | 2018-12-13 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.0300 | 3,700 | 4 | 12,800 | ||||
| 2018-12-14 | 2018-12-13 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.0400 | 4,100 | 4 | 9,100 | ||||
| 2018-12-14 | 2018-12-12 | 4 | Norbe Todd | BIOL | Common Stock | D | 1.0300 | 5,000 | 5 | 5,000 | ||||
| 2018-12-06 | 2018-12-03 | 4 | BEAVER JOHN R | BIOL | Common Stock | D | 1.1800 | 1,000 | 1 | 26,000 | ||||
| 2018-11-30 | 2018-11-29 | 4 | Sato Garrett | BIOL | Common Stock | D | 1.2200 | 5,000 | 6 | 10,000 | ||||
| 2018-11-20 | 2018-11-16 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 1.3600 | 10,000 | 14 | 577,145 | ||||
| 2018-10-09 | 2018-10-08 | 4 | Wagner Elaine C | BIOL | Restricted Stock Unit | D | 44,374 | 44,374 | ||||||
| 2018-09-25 | 2018-09-21 | 4 | Norbe Todd | BIOL | Restricted Stock Unit | D | 300,000 | 661,945 | ||||||
| 2018-09-25 | 2018-09-21 | 4 | Norbe Todd | BIOL | Restricted Stock Unit | D | 350,000 | 361,945 | ||||||
| 2018-08-17 | 2018-08-16 | 4 | BEAVER JOHN R | BIOL | Common Stock | D | 1.7000 | 18,923 | 32 | 25,000 | ||||
| 2018-08-17 | 2018-08-15 | 4 | BEAVER JOHN R | BIOL | Common Stock | D | 1.5800 | 6,077 | 10 | 6,077 | ||||
| 2018-08-14 | 2018-08-10 | 4 | Sato Garrett | BIOL | Common Stock | D | 1.3700 | 5,000 | 7 | 5,000 | ||||
| 2018-08-14 | 2018-08-14 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 1.4500 | 30,598 | 44 | 567,145 | ||||
| 2018-08-14 | 2018-08-10 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 1.2500 | 69,402 | 87 | 536,547 | ||||
| 2018-08-09 | 2018-08-07 | 4 | BEAVER JOHN R | BIOL | Stock Option (right to buy) | D | 1.20 | 60,000 | 760,000 | |||||
| 2018-06-19 | 2018-06-15 | 4 | Norbe Todd | BIOL | Restricted Stock Unit | D | 71,667 | 71,667 | ||||||
| 2018-06-19 | 2018-06-15 | 4 | ROPER JESS | BIOL | Restricted Stock Unit | D | 83,333 | 83,333 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | Sato Garrett | BIOL | Restricted Stock Unit | D | 81,034 | 81,034 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | Lanman Richard B. | BIOL | Restricted Stock Unit | D | 81,034 | 81,034 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | 91,379 | 109,587 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | 18,208 | 18,208 | ||||||
| 2018-05-14 | 2018-05-11 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | -7,394 | 0 | ||||||
| 2018-05-14 | 2018-05-11 | 4 | TALEVICH JAMES R | BIOL | Common Stock | D | 7,394 | 20,374 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 144,828 | 172,140 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 27,312 | 27,312 | ||||||
| 2018-05-14 | 2018-05-11 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | -7,042 | 0 | ||||||
| 2018-05-14 | 2018-05-11 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 7,042 | 100,470 | ||||||
| 2018-05-14 | 2018-05-14 | 4 | BEAVER JOHN R | BIOL | Restricted Stock Units | D | 97,911 | 97,911 | ||||||
| 2018-04-06 | 2018-04-04 | 4 | Sato Garrett | BIOL | Stock Option (right to buy) | D | 0.41 | 44,178 | 44,178 | |||||
| 2018-01-26 | 2018-01-25 | 4 | BEAVER JOHN R | BIOL | Stock Option (right to buy) | D | 0.42 | 100,000 | 700,000 | |||||
| 2017-12-06 | 2017-12-05 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.4560 | 10,745,615 | 4,900 | 30,866,265 | ||||
| 2017-12-06 | 2017-12-04 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 0.3000 | 1,800,000 | 540 | 20,120,650 | ||||
| 2017-12-06 | 2017-12-05 | 4 | TALEVICH JAMES R | BIOL | Subscription Rights (Right to Buy) | D | 0.46 | -3,189 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | TALEVICH JAMES R | BIOL | Common Stock | D | 0.4560 | 3,189 | 1 | 64,906 | ||||
| 2017-12-06 | 2017-12-05 | 4 | Flynn Harold C Jr. By Trust | BIOL | Subscription Rights (Right to Buy) | I | 0.46 | -65,870 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | Flynn Harold C Jr. By Trust | BIOL | Common Stock | I | 0.4560 | 65,870 | 30 | 131,970 | ||||
| 2017-12-06 | 2017-12-05 | 4 | LORD JONATHAN T MD | BIOL | Subscription Rights (Right to Buy) | D | 0.46 | -100,000 | 0 | |||||
| 2017-12-06 | 2017-12-05 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 0.4560 | 100,000 | 46 | 467,145 | ||||
| 2017-11-09 | 2017-11-08 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 0.57 | 19,737 | 578,131 | |||||
| 2017-11-09 | 2017-11-08 | 4 | TALEVICH JAMES R | BIOL | Stock Option (right to buy) | D | 0.57 | 9,868 | 454,638 | |||||
| 2017-11-09 | 2017-11-08 | 4 | Lanman Richard B. | BIOL | Stock Option (right to buy) | D | 0.57 | 9,868 | 145,201 | |||||
| 2017-11-02 | 2017-11-01 | 4 | Lanman Richard B. | BIOL | Stock Option (right to buy) | D | 0.76 | 135,333 | 135,333 | |||||
| 2017-10-04 | 2017-10-02 | 4 | BEAVER JOHN R | BIOL | Stock Option (right to buy) | D | 0.59 | 600,000 | 600,000 | |||||
| 2017-09-13 | 2017-09-12 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 0.61 | 65,891 | 558,394 | |||||
| 2017-09-13 | 2017-09-11 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 0.54 | 65,385 | 492,503 | |||||
| 2017-07-13 | 2017-01-04 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 1.5231 | 24,255 | 37 | 10,238,756 | ||||
| 2017-07-13 | 2017-01-03 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 1.4446 | 9,100 | 13 | 10,214,501 | ||||
| 2017-07-13 | 2016-12-30 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 1.3902 | 8,002 | 11 | 10,205,401 | ||||
| 2017-07-13 | 2016-12-29 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 1.4073 | 2,200 | 3 | 10,197,399 | ||||
| 2017-07-05 | 2017-06-30 | 4 | FEINBERG LARRY N | BIOL | Warrants to acquire Common Stock | I | 1.80 | 0.1250 | 1,800,535 | 225 | 3,144,811 | |||
| 2017-07-05 | 2017-06-30 | 4 | FEINBERG LARRY N | BIOL | Series D Preferred Stock | I | 1.24 | -36,986 | 0 | |||||
| 2017-07-05 | 2017-06-30 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.2400 | 3,698,600 | 4,586 | 18,320,650 | ||||
| 2017-07-03 | 2017-06-30 | 4 | MOLL FREDERIC H | BIOL | Series D Participating Convertible Preferred Stock | D | 1.24 | -1,921 | 0 | |||||
| 2017-07-03 | 2017-06-30 | 4 | MOLL FREDERIC H | BIOL | Common Stock | D | 1.2400 | 192,100 | 238 | 251,317 | ||||
| 2017-07-03 | 2017-06-30 | 4 | Flynn Harold C Jr. By Trust | BIOL | Series D Participating Convertible Preferred Stock | I | 1.24 | -307 | 0 | |||||
| 2017-07-03 | 2017-06-30 | 4 | Flynn Harold C Jr. By Trust | BIOL | Common Stock | I | 1.2400 | 30,700 | 38 | 66,100 | ||||
| 2017-07-03 | 2017-06-30 | 4 | CLARK PAUL N See Footnotes | BIOL | Series D Participating Convertible Preferred Stock | I | 1.24 | -1,563 | 0 | |||||
| 2017-07-03 | 2017-06-30 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock | I | 1.2400 | 156,300 | 194 | 1,311,557 | ||||
| 2017-07-03 | 2017-06-30 | 4 | LORD JONATHAN T MD | BIOL | Series D Participating Convertible Preferred Stock | D | 1.24 | -768 | 0 | |||||
| 2017-07-03 | 2017-06-30 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 1.2400 | 76,800 | 95 | 430,490 | ||||
| 2017-05-12 | 2017-05-10 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | 36,972 | 36,972 | ||||||
| 2017-05-12 | 2017-05-10 | 4 | TALEVICH JAMES R | BIOL | Stock Option (right to buy) | D | 1.21 | 110,915 | 444,770 | |||||
| 2017-05-12 | 2017-05-10 | 4 | CLARK PAUL N | BIOL | Restricted Stock Unit | D | 67,782 | 67,782 | ||||||
| 2017-05-12 | 2017-05-10 | 4 | CLARK PAUL N | BIOL | Stock Option (right to buy) | D | 1.21 | 203,345 | 754,221 | |||||
| 2017-05-12 | 2017-05-10 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 35,211 | 35,211 | ||||||
| 2017-05-12 | 2017-05-10 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 1.21 | 105,634 | 427,118 | |||||
| 2017-05-12 | 2017-05-10 | 4 | MOLL FREDERIC H | BIOL | Restricted Stock Unit | D | 35,211 | 35,211 | ||||||
| 2017-05-12 | 2017-05-10 | 4 | MOLL FREDERIC H | BIOL | Stock Option (right to buy) | D | 1.21 | 105,634 | 456,623 | |||||
| 2017-05-10 | 2017-05-08 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | -52,500 | 0 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | TALEVICH JAMES R | BIOL | Common Stock | D | 52,500 | 61,717 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | -50,000 | 0 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 50,000 | 353,690 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | MOLL FREDERIC H | BIOL | Restricted Stock Unit | D | -50,000 | 0 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | MOLL FREDERIC H | BIOL | Common Stock | D | 50,000 | 59,217 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | CLARK PAUL N | BIOL | Restricted Stock Unit | D | -96,250 | 0 | ||||||
| 2017-05-10 | 2017-05-08 | 4 | CLARK PAUL N | BIOL | Common Stock | D | 96,250 | 96,250 | ||||||
| 2017-04-19 | 2017-04-18 | 4 | CLARK PAUL N By Trust | BIOL | Warrants (right to buy) | I | 1.80 | 0.1250 | 76,089 | 10 | 76,089 | |||
| 2017-04-19 | 2017-04-18 | 4 | CLARK PAUL N By Trust | BIOL | Series D Participating Convertible Preferred Stock | I | 124.0000 | 1,536 | 190 | 1,536 | ||||
| 2017-04-19 | 2017-04-18 | 4 | Flynn Harold C Jr. By Trust | BIOL | Warrants (right to buy) | I | 1.80 | 0.1250 | 14,945 | 2 | 14,945 | |||
| 2017-04-19 | 2017-04-18 | 4 | Flynn Harold C Jr. By Trust | BIOL | Series D Participating Convertible Preferred Stock | I | 124.0000 | 307 | 38 | 307 | ||||
| 2017-04-19 | 2017-04-18 | 4 | LORD JONATHAN T MD | BIOL | Warrants (right to buy) | D | 1.80 | 0.1250 | 37,387 | 5 | 37,387 | |||
| 2017-04-19 | 2017-04-18 | 4 | LORD JONATHAN T MD | BIOL | Series D Participating Convertible Preferred Stock | D | 124.0000 | 768 | 95 | 768 | ||||
| 2017-04-19 | 2017-04-18 | 4 | MOLL FREDERIC H | BIOL | Warrants (right to buy) | D | 1.80 | 0.1250 | 93,517 | 12 | 93,517 | |||
| 2017-04-19 | 2017-04-18 | 4 | MOLL FREDERIC H | BIOL | Series D Participating Convertible Preferred Stock | D | 124.0000 | 1,921 | 238 | 1,921 | ||||
| 2017-04-19 | 2017-04-18 | 4 | Nelson Mark Joseph | BIOL | Warrants (right to buy) | D | 1.80 | 0.1250 | 9,346 | 1 | 9,346 | |||
| 2017-04-19 | 2017-04-18 | 4 | Nelson Mark Joseph | BIOL | Series D Participating Convertible Preferred Stock | D | 124.0000 | 192 | 24 | 192 | ||||
| 2017-03-27 | 2017-03-27 | 4 | Nelson Mark Joseph | BIOL | Stock Option (right to buy) | D | 1.28 | 600,000 | 600,000 | |||||
| 2017-03-23 | 2017-02-18 | 4 | Flynn Harold C Jr. | BIOL | Restricted Stock Unit | D | -29,761 | 1,435,000 | ||||||
| 2017-03-23 | 2017-02-18 | 4 | Flynn Harold C Jr. | BIOL | Common Stock | D | 29,761 | 96,720 | ||||||
| 2017-02-08 | 2017-02-06 | 4 | Flynn Harold C Jr. | BIOL | Restricted Stock Unit | D | 1,000,000 | 1,464,761 | ||||||
| 2016-12-06 | 2016-12-05 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.8500 | 46,463 | 86 | 14,608,464 | ||||
| 2016-12-06 | 2016-12-02 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.7800 | 53,537 | 95 | 14,562,001 | ||||
| 2016-11-23 | 2016-11-08 | 4/A | Flynn Harold C Jr. | BIOL | Restricted Stock Unit | D | 0 | 652,500 | ||||||
| 2016-11-23 | 2016-11-08 | 4/A | Flynn Harold C Jr. | BIOL | Stock Option (right to buy) | D | 1.45 | 1,000,000 | 2,307,903 | |||||
| 2016-11-17 | 2016-11-16 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.7100 | 33,674 | 58 | 14,508,464 | ||||
| 2016-11-17 | 2016-11-15 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.7200 | 18,514 | 32 | 14,478,326 | ||||
| 2016-11-14 | 2016-11-08 | 4 | Flynn Harold C Jr. | BIOL | Restricted Stock Unit | D | 1,000,000 | 1,652,500 | ||||||
| 2016-11-14 | 2016-11-08 | 4 | Flynn Harold C Jr. | BIOL | Stock Option (right to buy) | D | 1.45 | 1,000,000 | 1,652,500 | |||||
| 2016-11-14 | 2016-11-14 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.6100 | 33,674 | 54 | 14,459,812 | ||||
| 2016-11-14 | 2016-11-11 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.8100 | 48,513 | 88 | 14,426,138 | ||||
| 2016-11-14 | 2016-11-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.8100 | 42,000 | 76 | 14,377,625 | ||||
| 2016-11-10 | 2016-11-09 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.7000 | 125,000 | 212 | 14,335,625 | ||||
| 2016-11-10 | 2016-11-08 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.5200 | 2,000 | 3 | 14,230,625 | ||||
| 2016-10-07 | 2015-10-21 | 4/A | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9500 | 33,762 | 32 | 4,213,429 | ||||
| 2016-10-05 | 2016-09-30 | 4 | FEINBERG LARRY N | BIOL | Warrants to acquire Common Stock | I | 2.00 | 850,797 | 2,194,983 | |||||
| 2016-10-05 | 2016-09-30 | 4 | FEINBERG LARRY N | BIOL | Series C Preferred Stock | I | 1.13 | -37,091 | 0 | |||||
| 2016-10-05 | 2016-09-30 | 4 | FEINBERG LARRY N | BIOL | Common Stock | I | 1.1300 | 3,699,100 | 4,180 | 14,228,625 | ||||
| 2016-10-04 | 2016-09-30 | 4 | SCHULER JACK W By Trust | BIOL | Series C Participating Convertible Preferred Stock | I | 1.13 | -36,991 | 0 | |||||
| 2016-10-04 | 2016-09-30 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 1.1300 | 3,699,100 | 4,180 | 10,195,199 | ||||
| 2016-10-04 | 2016-09-30 | 4 | LORD JONATHAN T MD | BIOL | Series C Participating Convertible Preferred Stock | D | 1.13 | -1,770 | 0 | |||||
| 2016-10-04 | 2016-09-30 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 1.1300 | 177,000 | 200 | 303,690 | ||||
| 2016-10-04 | 2016-09-30 | 4 | CLARK PAUL N See Footnotes | BIOL | Series C Participating Convertible Preferred Stock | I | 1.13 | -2,212 | 0 | |||||
| 2016-10-04 | 2016-09-30 | 4 | CLARK PAUL N | BIOL | Common Stock | I | 1.1300 | 221,200 | 250 | 221,200 | ||||
| 2016-10-04 | 2016-09-30 | 4 | Flynn Harold C Jr. By Trust | BIOL | Series C Participating Convertible Preferred Stock | I | 1.13 | -354 | 0 | |||||
| 2016-10-04 | 2016-09-30 | 4 | Flynn Harold C Jr. By Trust | BIOL | Common Stock | I | 1.1300 | 35,400 | 40 | 35,400 | ||||
| 2016-08-29 | 2016-08-25 | 4 | Flynn Harold C Jr. | BIOL | Stock Option (right to buy) | D | 1.44 | 400,000 | 1,307,903 | |||||
| 2016-08-10 | 2016-08-08 | 4 | FEINBERG LARRY N See Footnotes | BIOL | Series C Preferred Stock | I | 1.13 | 1.1300 | 37,091 | 42 | 37,091 | |||
| 2016-08-10 | 2016-08-08 | 4 | FEINBERG LARRY N See Footnotes | BIOL | Warrants to acquire Common Stock | I | 2.00 | 0.1250 | 850,797 | 106 | 2,194,983 | |||
| 2016-08-03 | 2016-08-01 | 4 | Flynn Harold C Jr. By Trust | BIOL | Warrants (right to buy) | I | 2.00 | 0.1250 | 8,142 | 1 | 8,142 | |||
| 2016-08-03 | 2016-08-01 | 4 | Flynn Harold C Jr. By Trust | BIOL | Series C Participating Convertible Preferred Stock | I | 113.0000 | 354 | 40 | 354 | ||||
| 2016-08-03 | 2016-08-01 | 4 | LORD JONATHAN T MD | BIOL | Warrants (right to buy) | D | 2.00 | 0.1250 | 40,708 | 5 | 40,708 | |||
| 2016-08-03 | 2016-08-01 | 4 | LORD JONATHAN T MD | BIOL | Series C Participating Convertible Preferred Stock | D | 113.0000 | 1,770 | 200 | 1,770 | ||||
| 2016-08-03 | 2016-08-01 | 4 | CLARK PAUL N See Footnotes | BIOL | Warrants (right to buy) | I | 2.00 | 0.1250 | 50,885 | 6 | 50,885 | |||
| 2016-08-03 | 2016-08-01 | 4 | CLARK PAUL N See Footnotes | BIOL | Series C Participating Convertible Preferred Stock | I | 113.0000 | 2,212 | 250 | 2,212 | ||||
| 2016-08-03 | 2016-08-01 | 4 | SCHULER JACK W By Trust | BIOL | Warrants (right to buy) | I | 2.00 | 0.1250 | 850,796 | 106 | 850,796 | |||
| 2016-08-03 | 2016-08-01 | 4 | SCHULER JACK W By Trust | BIOL | Series C Participating Convertible Preferred Stock | I | 113.0000 | 36,991 | 4,180 | 36,991 | ||||
| 2016-07-05 | 2016-07-01 | 4 | DREYER DAVID C | BIOL | Restricted Stock Units | D | -70,000 | 0 | ||||||
| 2016-07-05 | 2016-07-01 | 4 | DREYER DAVID C | BIOL | Common Stock | D | 70,000 | 123,000 | ||||||
| 2016-05-11 | 2016-05-06 | 4 | MOLL FREDERIC H | BIOL | Restricted Stock Unit | D | 50,000 | 50,000 | ||||||
| 2016-05-11 | 2016-05-06 | 4 | MOLL FREDERIC H | BIOL | Stock Option (right to buy) | D | 1.41 | 120,152 | 350,989 | |||||
| 2016-05-10 | 2016-05-06 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 50,000 | 50,000 | ||||||
| 2016-05-10 | 2016-05-06 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 1.41 | 120,152 | 293,739 | |||||
| 2016-05-10 | 2016-05-06 | 4 | CLARK PAUL N | BIOL | Restricted Stock Unit | D | 96,250 | 96,250 | ||||||
| 2016-05-10 | 2016-05-06 | 4 | CLARK PAUL N | BIOL | Stock Option (right to buy) | D | 1.41 | 231,293 | 550,876 | |||||
| 2016-05-10 | 2016-05-06 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | 52,500 | 52,500 | ||||||
| 2016-05-10 | 2016-05-06 | 4 | TALEVICH JAMES R | BIOL | Stock Option (right to buy) | D | 1.41 | 126,160 | 333,855 | |||||
| 2016-04-04 | 2016-04-01 | 4 | Flynn Harold C Jr. | BIOL | Common Stock | D | 1.2600 | -12,803 | -16 | 66,959 | ||||
| 2016-04-04 | 2016-03-26 | 4 | Flynn Harold C Jr. | BIOL | Restricted Stock Units | D | -29,762 | 899,761 | ||||||
| 2016-04-04 | 2016-03-26 | 4 | Flynn Harold C Jr. | BIOL | Common Stock | D | 29,762 | 79,762 | ||||||
| 2016-03-14 | 2016-03-10 | 4 | DREYER DAVID C | BIOL | Restricted Stock Unit | D | 70,000 | 70,000 | ||||||
| 2016-02-26 | 2016-02-26 | 4 | Flynn Harold C Jr. | BIOL | Restricted Stock Unit | D | 59,523 | 929,523 | ||||||
| 2016-02-22 | 2016-02-18 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8000 | 500 | 0 | 6,547,537 | ||||
| 2016-02-18 | 2016-02-17 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8000 | 900 | 1 | 6,547,037 | ||||
| 2016-02-18 | 2016-02-16 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7981 | 3,200 | 3 | 6,546,137 | ||||
| 2016-02-16 | 2016-02-12 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7770 | 500 | 0 | 6,542,937 | ||||
| 2016-02-16 | 2016-02-11 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7557 | 18,580 | 14 | 6,542,437 | ||||
| 2016-02-11 | 2016-02-10 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7742 | 54,187 | 42 | 6,523,857 | ||||
| 2016-02-11 | 2016-02-09 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7896 | 13,026 | 10 | 6,469,670 | ||||
| 2016-01-27 | 2016-01-25 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8000 | 1,400 | 1 | 6,456,644 | ||||
| 2016-01-25 | 2016-01-22 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7720 | 1,870 | 1 | 6,455,244 | ||||
| 2016-01-25 | 2016-01-21 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7791 | 4,800 | 4 | 6,453,374 | ||||
| 2016-01-21 | 2016-01-20 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7367 | 19,900 | 15 | 6,448,574 | ||||
| 2016-01-21 | 2016-01-19 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7897 | 4,300 | 3 | 6,428,674 | ||||
| 2015-12-29 | 2015-12-28 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7887 | 18,350 | 14 | 6,424,374 | ||||
| 2015-12-28 | 2015-12-24 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7489 | 3,100 | 2 | 6,406,024 | ||||
| 2015-12-28 | 2015-12-23 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7575 | 38,800 | 29 | 6,402,924 | ||||
| 2015-12-23 | 2015-12-22 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7398 | 87,200 | 65 | 6,364,124 | ||||
| 2015-12-22 | 2015-12-21 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7342 | 126,919 | 93 | 6,276,924 | ||||
| 2015-12-22 | 2015-12-18 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.6806 | 973 | 1 | 6,150,005 | ||||
| 2015-12-18 | 3 | Jack W. Schuler Living Trust | BIOL | Common Stock | D | 11,771,206 | ||||||||
| 2015-12-18 | 3 | Jack W. Schuler Living Trust | BIOL | Common Stock | D | 11,771,206 | ||||||||
| 2015-12-18 | 2015-12-17 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7000 | 9,558 | 7 | 6,149,032 | ||||
| 2015-12-18 | 2015-12-16 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7048 | 24,600 | 17 | 6,139,474 | ||||
| 2015-12-18 | 2015-12-15 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7200 | 28,000 | 20 | 6,114,874 | ||||
| 2015-12-18 | 2015-12-14 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7400 | 42,923 | 32 | 6,086,874 | ||||
| 2015-12-18 | 2015-12-11 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7700 | 7,078 | 5 | 6,043,951 | ||||
| 2015-12-18 | 2015-12-10 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7800 | 31,699 | 25 | 6,036,873 | ||||
| 2015-12-18 | 2015-12-09 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7900 | 5,704 | 5 | 6,005,174 | ||||
| 2015-12-18 | 2015-12-08 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7900 | 14,596 | 12 | 5,999,470 | ||||
| 2015-12-18 | 2015-12-07 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8000 | 8,561 | 7 | 5,984,874 | ||||
| 2015-12-18 | 2015-12-04 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8100 | 5,286 | 4 | 5,976,313 | ||||
| 2015-12-18 | 2015-12-03 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8100 | 16,427 | 13 | 5,971,027 | ||||
| 2015-12-18 | 2015-12-02 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8500 | 5,900 | 5 | 5,954,600 | ||||
| 2015-12-18 | 2015-11-30 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9000 | 16,752 | 15 | 5,948,700 | ||||
| 2015-12-18 | 2015-11-26 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8900 | 2,045 | 2 | 5,931,948 | ||||
| 2015-12-18 | 2015-11-25 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9000 | 44,200 | 40 | 5,929,903 | ||||
| 2015-12-18 | 2015-11-24 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9200 | 100 | 0 | 5,885,703 | ||||
| 2015-12-18 | 2015-11-23 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9300 | 64,865 | 60 | 5,885,603 | ||||
| 2015-12-18 | 2015-11-17 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9500 | 200 | 0 | 5,820,738 | ||||
| 2015-12-18 | 2015-11-16 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9500 | 5,400 | 5 | 5,820,538 | ||||
| 2015-12-18 | 2015-11-13 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8600 | 93,409 | 80 | 5,815,138 | ||||
| 2015-12-18 | 2015-11-12 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7800 | 234,313 | 183 | 5,721,729 | ||||
| 2015-12-18 | 2015-11-11 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7700 | 33,099 | 25 | 5,487,416 | ||||
| 2015-12-18 | 2015-11-06 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.6300 | 140,000 | 88 | 5,454,317 | ||||
| 2015-12-18 | 2015-11-05 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.7700 | 505,974 | 390 | 5,314,317 | ||||
| 2015-12-18 | 2015-10-28 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9000 | 5,671 | 5 | 4,808,343 | ||||
| 2015-12-18 | 2015-10-27 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9100 | 9,900 | 9 | 4,802,672 | ||||
| 2015-12-18 | 2015-10-26 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9200 | 23,500 | 22 | 4,792,772 | ||||
| 2015-12-18 | 2015-10-23 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9200 | 48,250 | 44 | 4,769,272 | ||||
| 2015-12-18 | 2015-10-22 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9200 | 541,355 | 498 | 4,721,022 | ||||
| 2015-12-18 | 2015-10-20 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9500 | 52,103 | 49 | 4,179,667 | ||||
| 2015-12-18 | 2015-10-19 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9500 | 25,510 | 24 | 4,127,564 | ||||
| 2015-12-18 | 2015-10-16 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9600 | 1,000 | 1 | 4,102,054 | ||||
| 2015-12-18 | 2015-10-15 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9600 | 2,970 | 3 | 4,101,054 | ||||
| 2015-12-18 | 2015-10-14 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9600 | 13,418 | 13 | 4,098,084 | ||||
| 2015-12-18 | 2015-10-13 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9900 | 100,000 | 99 | 4,084,666 | ||||
| 2015-12-18 | 2015-10-12 | 4 | SCHULER JACK W By spouse | BIOL | Common Stock | I | 1.0300 | 14,800 | 15 | 14,800 | ||||
| 2015-12-18 | 2015-10-12 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 1.0300 | 100,000 | 103 | 3,984,666 | ||||
| 2015-12-18 | 2015-10-09 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9500 | 1,100,000 | 1,045 | 3,884,666 | ||||
| 2015-12-18 | 2015-10-08 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9000 | 500 | 0 | 2,784,666 | ||||
| 2015-12-18 | 2015-10-02 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.8900 | 169,361 | 151 | 2,784,166 | ||||
| 2015-12-18 | 2015-10-01 | 4 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 0.9300 | 10,639 | 10 | 2,614,805 | ||||
| 2015-11-12 | 2015-11-11 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 0.7934 | 54,800 | 43 | 10,529,525 | ||||
| 2015-11-12 | 2015-11-09 | 4 | Flynn Harold C Jr. | BIOL | Common Stock, par value $0.001 per share | D | 0.8000 | 22,100 | 18 | 50,000 | ||||
| 2015-11-12 | 2015-11-09 | 4 | Flynn Harold C Jr. | BIOL | Common Stock, par value $0.001 per share | D | 0.7800 | 5,333 | 4 | 27,900 | ||||
| 2015-11-12 | 2015-11-09 | 4 | Flynn Harold C Jr. | BIOL | Common Stock, par value $0.001 per share | D | 0.7700 | 12,567 | 10 | 22,567 | ||||
| 2015-11-12 | 2015-11-09 | 4 | Flynn Harold C Jr. | BIOL | Common Stock, par value $0.001 per share | D | 0.7200 | 10,000 | 7 | 10,000 | ||||
| 2015-11-12 | 2015-11-10 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7600 | 32,500 | 25 | 1,155,257 | ||||
| 2015-11-12 | 2015-11-10 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7500 | 23,501 | 18 | 1,122,757 | ||||
| 2015-11-12 | 2015-11-10 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7400 | 39,699 | 29 | 1,099,256 | ||||
| 2015-11-12 | 2015-11-10 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7300 | 4,300 | 3 | 1,059,557 | ||||
| 2015-11-12 | 2015-11-09 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7900 | 10,210 | 8 | 1,055,257 | ||||
| 2015-11-12 | 2015-11-09 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7800 | 2,923 | 2 | 1,045,047 | ||||
| 2015-11-12 | 2015-11-09 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7700 | 2,800 | 2 | 1,042,124 | ||||
| 2015-11-12 | 2015-11-09 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7600 | 7,000 | 5 | 1,039,324 | ||||
| 2015-11-12 | 2015-11-09 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 0.7500 | 11,646 | 9 | 1,032,324 | ||||
| 2015-11-12 | 2015-11-09 | 4 | LORD JONATHAN T MD | BIOL | Common Stock, par value $0.001 per share | D | 0.7500 | 16,310 | 12 | 126,690 | ||||
| 2015-11-12 | 2015-11-09 | 4 | DREYER DAVID C | BIOL | Common Stock, par value $0.001 per share | D | 0.7700 | 33,000 | 25 | 53,000 | ||||
| 2015-09-25 | 2015-09-24 | 4 | DREYER DAVID C | BIOL | Common Stock | D | 1.2000 | 5,000 | 6 | 20,000 | ||||
| 2015-09-24 | 2015-09-22 | 4 | DREYER DAVID C | BIOL | Common Stock | D | 1.3700 | 5,000 | 7 | 15,000 | ||||
| 2015-09-17 | 2015-09-17 | 4 | DREYER DAVID C | BIOL | Common Stock | D | 1.4500 | 10,000 | 14 | 10,000 | ||||
| 2015-08-31 | 2015-08-27 | 4 | MOLL FREDERIC H | BIOL | Restricted Stock Unit | D | -9,217 | 0 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | MOLL FREDERIC H | BIOL | Common Stock | D | 9,217 | 9,217 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | -9,217 | 0 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | TALEVICH JAMES R | BIOL | Common Stock | D | 9,217 | 9,217 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | CLARK PAUL N | BIOL | Restricted Stock Unit | D | -9,217 | 0 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | CLARK PAUL N | BIOL | Common Stock | D | 9,217 | 1,020,678 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | -9,217 | 0 | ||||||
| 2015-08-31 | 2015-08-27 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 9,217 | 110,380 | ||||||
| 2015-07-20 | 2015-07-13 | 4 | Flynn Harold C Jr. | BIOL | Restricted Stock Unit | D | 870,000 | 870,000 | ||||||
| 2015-07-20 | 2015-07-13 | 4 | Flynn Harold C Jr. | BIOL | Stock Option (right to buy) | D | 1.65 | 870,000 | 870,000 | |||||
| 2015-06-25 | 2015-03-09 | 4/A | DREYER DAVID C | BIOL | Stock Option (right to buy) | D | 1.99 | 871,710 | 871,710 | |||||
| 2015-04-29 | 2015-04-27 | 4 | CLARK PAUL N | BIOL | Stock Option (right to buy) | D | 2.27 | 254,405 | 319,583 | |||||
| 2015-04-29 | 2015-04-27 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 2.27 | 132,159 | 173,587 | |||||
| 2015-04-29 | 2015-04-27 | 4 | TALEVICH JAMES R | BIOL | Stock Option (right to buy) | D | 2.27 | 138,767 | 207,695 | |||||
| 2015-04-29 | 2015-04-27 | 4 | MOLL FREDERIC H | BIOL | Stock Option (right to buy) | D | 2.27 | 132,159 | 230,837 | |||||
| 2015-03-19 | 2015-03-09 | 4 | DREYER DAVID C | BIOL | Stock Option (right to buy) | D | 1.99 | 871,710 | 871,710 | |||||
| 2014-11-13 | 3 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 5,208,332 | ||||||||
| 2014-11-13 | 3 | SCHULER JACK W By Trust | BIOL | Common Stock | I | 5,208,332 | ||||||||
| 2014-11-06 | 2014-11-03 | 4 | FEINBERG LARRY N | BIOL | Warrants (right to buy) | I | 4.00 | 0.1250 | 470,465 | 59 | 470,465 | |||
| 2014-11-06 | 2014-11-03 | 4 | FEINBERG LARRY N | BIOL | Warrants (right to buy) | I | 4.00 | 0.1250 | 336,047 | 42 | 336,047 | |||
| 2014-11-06 | 2014-11-03 | 4 | FEINBERG LARRY N | BIOL | Warrants (right to buy) | I | 4.00 | 0.1250 | 537,674 | 67 | 537,674 | |||
| 2014-11-06 | 2014-11-03 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.3900 | 723,792 | 1,730 | 1,586,737 | ||||
| 2014-11-06 | 2014-11-03 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.3900 | 516,995 | 1,236 | 6,374,246 | ||||
| 2014-11-06 | 2014-11-03 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.3900 | 827,192 | 1,977 | 2,513,742 | ||||
| 2014-11-05 | 2014-11-03 | 4 | LORD JONATHAN T MD | BIOL | Warrants (right to buy) | D | 4.00 | 0.1250 | 65,755 | 8 | 65,755 | |||
| 2014-11-05 | 2014-11-03 | 4 | LORD JONATHAN T MD | BIOL | Common Stock | D | 2.3900 | 101,163 | 242 | 101,163 | ||||
| 2014-11-05 | 2014-11-03 | 4 | Nugent Jeffrey M | BIOL | Warrants (right to buy) | D | 4.00 | 0.1250 | 26,302 | 3 | 26,302 | |||
| 2014-11-05 | 2014-11-03 | 4 | Nugent Jeffrey M | BIOL | Common Stock | D | 2.3900 | 40,465 | 97 | 92,548 | ||||
| 2014-11-05 | 2014-11-03 | 4 | CLARK PAUL N By Trust | BIOL | Warrants (right to buy) | I | 4.00 | 0.1250 | 263,024 | 33 | 263,024 | |||
| 2014-11-05 | 2014-11-03 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock | I | 2.3900 | 404,653 | 967 | 1,010,607 | ||||
| 2014-09-03 | 2014-08-29 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 2.16 | 27,745 | 69,173 | |||||
| 2014-08-29 | 2014-08-27 | 4 | LORD JONATHAN T MD | BIOL | Restricted Stock Unit | D | 9,217 | 9,217 | ||||||
| 2014-08-29 | 2014-08-27 | 4 | LORD JONATHAN T MD | BIOL | Stock Option (right to buy) | D | 2.17 | 41,428 | 41,428 | |||||
| 2014-08-29 | 2014-08-27 | 4 | CLARK PAUL N | BIOL | Restricted Stock Unit | D | 9,217 | 9,217 | ||||||
| 2014-08-29 | 2014-08-27 | 4 | CLARK PAUL N | BIOL | Stock Option (right to buy) | D | 2.17 | 41,428 | 65,178 | |||||
| 2014-08-29 | 2014-08-27 | 4 | TALEVICH JAMES R | BIOL | Restricted Stock Unit | D | 9,217 | 9,217 | ||||||
| 2014-08-29 | 2014-08-27 | 4 | TALEVICH JAMES R | BIOL | Stock Option (right to buy) | D | 2.17 | 41,428 | 68,928 | |||||
| 2014-08-29 | 2014-08-27 | 4 | MOLL FREDERIC H | BIOL | Restricted Stock Unit | D | 9,217 | 9,217 | ||||||
| 2014-08-29 | 2014-08-27 | 4 | MOLL FREDERIC H | BIOL | Stock Option (right to buy) | D | 2.17 | 41,428 | 98,678 | |||||
| 2014-07-23 | 3 | CLARK PAUL N By trust | BIOL | Common Stock, par value $0.001 per share | I | 170,242 | ||||||||
| 2014-07-23 | 3 | CLARK PAUL N By trust | BIOL | Common Stock, par value $0.001 per share | I | 170,242 | ||||||||
| 2014-07-23 | 2014-07-22 | 4 | CLARK PAUL N By Trust | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 520,833 | 1,000 | 605,954 | ||||
| 2014-07-23 | 2014-07-13 | 4 | Nugent Jeffrey M | BIOL | Restricted Stock Unit | D | 37,879 | 37,879 | ||||||
| 2014-07-23 | 2014-07-13 | 4 | Nugent Jeffrey M | BIOL | Stock Option (right to buy) | D | 1.98 | 172,282 | 172,282 | |||||
| 2014-07-23 | 2014-07-22 | 4 | Nugent Jeffrey M | BIOL | Common Stock, par value $0.001 per share | D | 1.9200 | 52,083 | 100 | 52,083 | ||||
| 2014-07-23 | 2014-07-22 | 4 | Furry Frederick D. | BIOL | Common Stock | D | 1.9200 | 13,020 | 25 | 18,020 | ||||
| 2014-07-23 | 2014-07-22 | 4 | Arrow Alexander K. | BIOL | Common Stock | D | 1.9200 | 7,812 | 15 | 110,387 | ||||
| 2014-07-22 | 2014-07-18 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 260,756 | 501 | 862,945 | ||||
| 2014-07-22 | 2014-07-18 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 1,641,036 | 3,151 | 5,857,251 | ||||
| 2014-07-22 | 2014-07-18 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 369,044 | 709 | 1,686,550 | ||||
| 2014-02-12 | 2014-02-12 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5900 | 2,900 | 8 | 599,194 | ||||
| 2014-02-12 | 2014-02-12 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5900 | 25,729 | 67 | 4,195,237 | ||||
| 2014-02-12 | 2014-02-12 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5900 | 6,200 | 16 | 1,310,952 | ||||
| 2014-02-12 | 2014-02-11 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.6900 | 2,500 | 7 | 596,294 | ||||
| 2014-02-12 | 2014-02-11 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.6900 | 22,044 | 59 | 4,169,508 | ||||
| 2014-02-12 | 2014-02-11 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.6900 | 5,300 | 14 | 1,304,752 | ||||
| 2014-02-12 | 2014-02-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5700 | 280,000 | 720 | 593,794 | ||||
| 2014-02-12 | 2014-02-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5300 | 2,500 | 6 | 313,794 | ||||
| 2014-02-12 | 2014-02-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5700 | 1,345,525 | 3,458 | 4,147,464 | ||||
| 2014-02-12 | 2014-02-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5300 | 18,335 | 46 | 2,801,939 | ||||
| 2014-02-12 | 2014-02-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5700 | 320,000 | 822 | 1,299,452 | ||||
| 2014-02-12 | 2014-02-10 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.5300 | 4,000 | 10 | 979,452 | ||||
| 2014-02-04 | 2014-01-31 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.4500 | 2,600 | 6 | 311,294 | ||||
| 2014-02-04 | 2014-01-31 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.4500 | 22,698 | 56 | 2,783,604 | ||||
| 2014-02-04 | 2014-01-31 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 2.4500 | 5,500 | 13 | 975,452 | ||||
| 2013-12-20 | 2013-12-10 | 4 | LOW SAMUEL BERNARD | BIOL | Stock Option (right to buy) | D | 1.73 | 27,500 | 27,500 | |||||
| 2013-12-20 | 2013-12-10 | 4 | TALEVICH JAMES R | BIOL | Stock Option (right to buy) | D | 1.73 | 27,500 | 27,500 | |||||
| 2013-12-20 | 2013-12-19 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.8000 | 340,000 | 612 | 967,000 | ||||
| 2013-12-18 | 3 | FEINBERG LARRY N See Footnotes | BIOL | Common Stock, par value $0.001 per share | I | 2,633,746 | ||||||||
| 2013-12-18 | 3 | FEINBERG LARRY N See Footnotes | BIOL | Common Stock, par value $0.001 per share | I | 294,854 | ||||||||
| 2013-12-18 | 3 | FEINBERG LARRY N See Footnotes | BIOL | Common Stock, par value $0.001 per share | I | 603,300 | ||||||||
| 2013-12-18 | 2013-12-17 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 4,000 | 8 | 627,000 | ||||
| 2013-12-18 | 2013-12-17 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 2,100 | 4 | 307,254 | ||||
| 2013-12-18 | 2013-12-17 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.9200 | 19,300 | 37 | 2,748,046 | ||||
| 2013-12-18 | 2013-12-16 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.8600 | 19,700 | 37 | 623,000 | ||||
| 2013-12-18 | 2013-12-16 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.8600 | 10,300 | 19 | 305,154 | ||||
| 2013-12-18 | 2013-12-16 | 4 | FEINBERG LARRY N | BIOL | Common Stock, par value $0.001 per share | I | 1.8600 | 95,000 | 177 | 2,728,746 | ||||
| 2013-06-14 | 2013-06-07 | 4 | ENRIGHT ERIN S. | BIOL | Stock Option (right to buy) | D | 4.07 | 35,000 | 35,000 | |||||
| 2013-06-11 | 2013-06-06 | 4 | Arrow Alexander K. | BIOL | Stock Option (right to buy) | D | 4.00 | 350,000 | 474,500 | |||||
| 2013-06-11 | 2013-06-07 | 4 | MOLL FREDERIC H | BIOL | Stock Option (right to buy) | D | 4.07 | 22,250 | 57,250 | |||||
| 2013-06-11 | 2013-06-07 | 4 | MOLL FREDERIC H | BIOL | Stock Option (right to buy) | D | 4.07 | 35,000 | 35,000 | |||||
| 2013-06-10 | 2013-06-06 | 4 | Nemoy Norman J. | BIOL | Stock Option (right to buy) | D | 4.00 | 20,000 | 153,500 | |||||
| 2013-06-10 | 2013-06-06 | 4 | LICHTWARDT GREGORY | BIOL | Stock Option (right to buy) | D | 4.00 | 20,000 | 130,750 | |||||
| 2013-03-26 | 2013-03-23 | 4 | Furry Frederick D. | BIOL | Stock Option (right to buy) | D | 5.00 | 50,000 | 247,500 | |||||
| 2012-11-13 | 2012-11-08 | 4 | PIGNATELLI FEDERICO | BIOL | Stock Option (right to buy) | D | 2.50 | 100,000 | 270,000 | |||||
| 2012-08-23 | 2012-08-23 | 4 | Furry Frederick D. | BIOL | Common Stock | D | 1.6500 | 1,000 | 2 | 5,000 | ||||
| 2012-08-23 | 2012-08-21 | 4 | Furry Frederick D. | BIOL | Common Stock | D | 1.6400 | 4,000 | 7 | 4,000 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.8300 | 7,500 | 14 | 92,575 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.8000 | 9,000 | 16 | 85,075 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7800 | 300 | 1 | 76,075 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7700 | 7,500 | 13 | 75,775 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7600 | 3,200 | 6 | 68,275 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7500 | 1,600 | 3 | 65,075 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7400 | 300 | 1 | 63,475 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7300 | 4,400 | 8 | 63,175 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7200 | 1,900 | 3 | 58,775 | ||||
| 2012-08-15 | 2012-08-13 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7100 | 1,300 | 2 | 56,875 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.6900 | 400 | 1 | 102,575 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.6800 | 723 | 1 | 102,175 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.6700 | 4,800 | 8 | 101,452 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7000 | 377 | 1 | 96,652 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7300 | 1,237 | 2 | 96,275 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7200 | 1,100 | 2 | 95,038 | ||||
| 2012-08-15 | 2012-08-14 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 1.7100 | 1,363 | 2 | 93,998 | ||||
| 2012-06-05 | 2012-05-15 | 4/A | Arrow Alexander K. | BLTI | Common Stock | D | 2.4100 | 2,000 | 5 | 50,775 | ||||
| 2012-06-05 | 2012-06-01 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 2.3600 | 3,000 | 7 | 55,575 | ||||
| 2012-06-05 | 2012-06-01 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 2.3900 | 200 | 0 | 52,575 | ||||
| 2012-06-05 | 2012-06-01 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 2.3300 | 1,600 | 4 | 52,375 | ||||
| 2012-05-29 | 2012-05-10 | 4 | Arrow Alexander K. | BLTI | Stock Option (right to buy) | D | 2.56 | 20,000 | 124,500 | |||||
| 2012-05-29 | 2012-05-10 | 4 | Nemoy Norman J. | BLTI | Stock Option (right to buy) | D | 2.56 | 20,000 | 133,500 | |||||
| 2012-05-29 | 2012-05-10 | 4 | LICHTWARDT GREGORY | BLTI | Stock Option (right to buy) | D | 2.56 | 20,000 | 110,750 | |||||
| 2012-05-18 | 2012-05-15 | 4 | Arrow Alexander K. | BLTI | Common Stock | D | 2.4100 | 2,000 | 5 | 50,775 | ||||
| 2012-03-14 | 2012-03-13 | 4 | PIGNATELLI FEDERICO | BLTI | Stock Option (right to buy) | D | 2.54 | 2.5400 | -100,000 | -254 | 200,000 | |||
| 2012-03-14 | 2012-03-13 | 4 | PIGNATELLI FEDERICO | BLTI | Common Stock | D | 2.5800 | 100,000 | 258 | 1,725,250 | ||||
| 2012-03-06 | 2011-12-23 | 4/A | PIGNATELLI FEDERICO | BLTI | Stock Option (right to buy) | D | 2.58 | 100,000 | 300,000 | |||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.2500 | 4,300 | 14 | 40,000 | ||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.2400 | 600 | 2 | 35,700 | ||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.2300 | 100 | 0 | 35,100 | ||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.2200 | 4,000 | 13 | 35,000 | ||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.2100 | 200 | 1 | 31,000 | ||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.2000 | 600 | 2 | 30,800 | ||||
| 2008-06-03 | 2008-05-30 | 4 | ST PHILIP JAKE | BLTI | Common Stock | D | 3.1800 | 200 | 1 | 30,200 | ||||
| 2008-01-09 | 2008-01-07 | 4 | Anderton Robert M | BLTI | Stock Option (right to buy) | D | 2.89 | 10,000 | 10,000 | |||||
| 2008-01-09 | 2008-01-07 | 4 | dArbeloff George V | BLTI | Stock Option (right to buy) | D | 2.89 | 25,000 | 25,000 | |||||
| 2008-01-09 | 2008-01-07 | 4 | DURRIE DANIEL S | BLTI | Stock Option (right to buy) | D | 2.89 | 10,000 | 10,000 | |||||
| 2008-01-09 | 2008-01-07 | 4 | Largent James R | BLTI | Stock Option (right to buy) | D | 2.89 | 10,000 | 10,000 | |||||
| 2008-01-09 | 2008-01-07 | 4 | PIGNATELLI FEDERICO | BLTI | Stock Option (right to buy) | D | 2.89 | 100,000 | 0 | |||||
| 2008-01-09 | 2008-01-07 | 4 | LAIRD NEIL J | BLTI | Stock Option (right to buy) | D | 2.89 | 25,000 | 25,000 | |||||
| 2007-06-29 | 2007-06-27 | 4 | Bateman Keith G | BLTI | Stock Option (right to buy) | D | 5.95 | 30,000 | 30,000 | |||||
| 2006-04-21 | 2006-04-20 | 4 | dArbeloff George V | BLTI | Stock Option (right to buy) | D | 10.40 | 30,000 | 30,000 | |||||
| 2006-04-21 | 2006-04-20 | 4 | Anderton Robert M | BLTI | Stock Option (right to buy) | D | 10.40 | 30,000 | 30,000 | |||||
| 2006-04-21 | 2006-04-20 | 4 | PIGNATELLI FEDERICO | BLTI | Stock Option (right to buy) | D | 10.40 | 30,000 | 30,000 | |||||
| 2006-04-17 | 2001-08-24 | 4/A | Jones Jeffrey W | BLTI | Common Stock | D | 4.0300 | 1,000 | 4 | 6,000 | ||||
| 2005-10-18 | 2005-06-01 | 4 | Haefner James | BLTI | Employee Stock Option (right to buy) | D | 7.14 | 20,000 | 20,000 | |||||
| 2005-01-07 | 3/A | HOHENER JOHN W | BLTI | Common Stock | D | 0 |
P
非衍生或衍生證券的公開市場或私下買入
S
非衍生或衍生證券的公開市場或私下賣出
A
公司向內部人員授予、獎勵或以其他方式獲取證券（例如股票期權）
C
衍生工具轉換
D
將證券賣出或轉讓回公司
F
使用從公司收到的證券的一部分來支付行使價或稅務負擔。
G
內部人士贈送或接收他人贈送公司股票
K
股權掉期和類似的避險交易
M
行使或轉換從公司獲得的衍生證券（例如期權）
V
內部人士透過Form 4自願報告的一筆交易
J
其他（附有交易描述的腳註）
