英維維德公司
US ˙ NasdaqGM ˙ US00534A1025

簡介

本頁面提供了有關 Jonathan A Flint 已知的內部交易歷史的全面分析。內部人士包括公司的高管、董事或重要投資者。一般而言，基於內幕、非公開信息進行交易是非法的。這並不意味著他們在自己的公司進行任何交易都是非法的。但是，他們必須透過Form 4向美國證券交易委員會（SEC）報告所有交易。盡管存在這些限制，學術研究表明，內部人士 - 整體而言 - 在自己公司中的投資表現往往優於市場。

平均交易盈利能力

「平均交易盈利能力」衡量了內部人士在過去三年中所有非計劃性的公開市場購買交易的平均回報率。計算過程包括檢查每筆交易，排除了作為10b5-1交易計劃的一部分的交易。然後，對每筆交易在3、6和12個月的表現進行平均，以生成該筆交易最終的表現指標。最終，將所有交易的表現指標進行平均，計算出內部人士的總體平均表現指標。列表僅包含在過去兩年中進行過至少三筆交易的內部人士。

如果內部人士的交易盈利能力顯示為"N/A"，則可能是因為該內部人士在過去三年內沒有進行任何公開市場購買交易，或者他們進行的交易距離現在太近，無法計算出可靠的表現指標。

更新頻率：每日

查看收益最高的的內幕交易者列表。

查看排名最高的內部人士。
報告內部持倉的公司

SEC文件顯示Jonathan A Flint已報告在以下公司擁有持倉或進行了交易：

證券 職位 最新報告的持倉
US:ADGI / Adagio Therapeutics Inc 3,120,194
US:LYRA / Lyra Therapeutics, Inc. 10% Owner 0
US:PHR / Phreesia, Inc. 10% Owner 31,015
US:PULM / Pulmatrix, Inc. 10% Owner 7,700
US:ASNS / Actelis Networks, Inc. 10% Owner 0
US:TRVN / Trevena, Inc. 10% Owner 36,369
US:BIND / BIND Therapeutics, Inc. 10% Owner 0
US:ALIM / Alimera Sciences, Inc. 10% Owner 3,090,769
US:ALNY / Alnylam Pharmaceuticals, Inc. 10% Owner 37,074
US:PII / Polaris Inc. 10% Owner 37,178
如何解讀這些圖表

以下圖表顯示了在Jonathan A Flint進行的每筆公開市場非計劃交易後證券的股價表現。非計劃交易是指沒有作為10b5-1交易計劃的一部分而進行的交易。股價表現以累積百分比變化的方式繪製。例如，如果一筆內部人士交易是在2019年1月1日進行的，該圖表將顯示該證券的每日百分比變化直至當前日期。如果在此期間股價從10美元漲至15美元，則股價的累積百分比變化將為50%。從10美元漲至20美元的價格變化將為100%，而從10美元跌至5美元的價格變化將為-50%。

最終，我們將評估內部人士的交易與股價的超額回報（正向或負向）之間的相關性，以判斷內部人士是否在交易中利用內部信息獲利。如果內部人士有這樣的行為，我們預期看到（a）購買後的正回報，或者（b）賣出後的負回報。對於情況（a），購買圖表將顯示一系列向上傾斜的曲線，表示每次購買後都有正回報。對於情況（b），賣出圖表將顯示一系列向下傾斜的曲線，表示每次賣出後都有負回報。

然而，僅憑這一點還不足以得出結論。例如，如果公司的股價在多年內呈現非周期性上升，我們會預期所有購買後的圖表都呈現向上傾斜。同樣地，多年來呈現非周期性下降的股價會導致賣出後的圖表也呈現向下傾斜。這兩種情況的圖表都不能表示內部人士在進行內幕交易。

最有力的指標是在公司股價呈極度循環波動的情況下，「購買」圖表顯示正向信號，而「賣出」圖表顯示負向趨勢。這種情況強烈暗示內部人士可能根據內幕信息精確地計時進行交易，以獲得財務優勢。

IVVD / Invivyd, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

IVVD / Invivyd, Inc. Insider Trades
IVVD / Invivyd, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

IVVD / Invivyd, Inc. Insider Trades
LYRA / Lyra Therapeutics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 60,308 16.0000 1,206 800.0000 964,928 0 16.65 -944,848 -97.92
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 1,176 16.0000 24 800.0000 18,816
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 603 16.0000 12 800.0000 9,648
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 413 16.0000 8 800.0000 6,608

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

LYRA / Lyra Therapeutics, Inc. Insider Trades
LYRA / Lyra Therapeutics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 9,334 16.0000 187 800.0000 149,344 365 8.44 -147,774 -98.95
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 182 16.0000 4 800.0000 2,912
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 94 16.0000 2 800.0000 1,504
2020-05-05 LYRA Polaris Venture Management Co. V, L.L.C. 64 16.0000 1 800.0000 1,024

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

LYRA / Lyra Therapeutics, Inc. Insider Trades
PHR / Phreesia, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

PHR / Phreesia, Inc. Insider Trades
PHR / Phreesia, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
2019-12-17 PHR Polaris Venture Management Co. V, L.L.C. 344,599 24.4790 344,599 24.4790 8,435,439 92 16.59 -2,718,541 -32.23
2019-12-17 PHR Polaris Venture Management Co. V, L.L.C. 6,716 24.4790 6,716 24.4790 164,401
2019-12-17 PHR Polaris Venture Management Co. V, L.L.C. 2,360 24.4790 2,360 24.4790 57,770
2019-12-17 PHR Polaris Venture Management Co. V, L.L.C. 3,446 24.4790 3,446 24.4790 84,355
2019-07-22 PHR Polaris Venture Management Co. V, L.L.C. 382,887 18.0000 382,887 18.0000 6,891,966
2019-07-22 PHR Polaris Venture Management Co. V, L.L.C. 7,462 18.0000 7,462 18.0000 134,316
2019-07-22 PHR Polaris Venture Management Co. V, L.L.C. 2,622 18.0000 2,622 18.0000 47,196
2019-07-22 PHR Polaris Venture Management Co. V, L.L.C. 3,828 18.0000 3,828 18.0000 68,904

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

PHR / Phreesia, Inc. Insider Trades
PULM / Pulmatrix, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2018-04-03 PULM MCGUIRE TERRANCE 345,551 23,037 69 120
2018-04-03 PULM MCGUIRE TERRANCE 6,478 432
2018-04-03 PULM MCGUIRE TERRANCE 769,989 51,333
2018-04-03 PULM MCGUIRE TERRANCE 15,007 1,000
2018-04-03 PULM MCGUIRE TERRANCE 5,275 352
2018-04-03 PULM MCGUIRE TERRANCE 7,700 513
2015-06-15 PULM MCGUIRE TERRANCE 32,059 6.8750 2,959 74.4792 220,406
2015-06-15 PULM MCGUIRE TERRANCE 601 6.8750 55 74.4792 4,132
2015-06-15 PULM MCGUIRE TERRANCE 71,438 6.8750 6,594 74.4792 491,136
2015-06-15 PULM MCGUIRE TERRANCE 489 6.8750 45 74.4792 3,362
2015-06-15 PULM MCGUIRE TERRANCE 714 6.8750 66 74.4792 4,909
2015-06-15 PULM MCGUIRE TERRANCE 1,392 6.8750 128 74.4792 9,570
2015-06-15 PULM MCGUIRE TERRANCE 71,439 6.8750 6,594 74.4792 491,143
2015-06-15 PULM MCGUIRE TERRANCE 490 6.8750 45 74.4792 3,369
2015-06-15 PULM MCGUIRE TERRANCE 715 6.8750 66 74.4792 4,916
2015-06-15 PULM MCGUIRE TERRANCE 1,392 6.8750 128 74.4792 9,570

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

PULM / Pulmatrix, Inc. Insider Trades
PULM / Pulmatrix, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

PULM / Pulmatrix, Inc. Insider Trades
TRVN / Trevena, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2014-02-05 TRVN Polaris Venture Management Co. V, L.L.C. 472,405 7.0000 18,896 175.0000 3,306,835 28 241 1,247,101 37.71

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

TRVN / Trevena, Inc. Insider Trades
TRVN / Trevena, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 IVVD / Invivyd, Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
2014-08-14 TRVN Polaris Venture Management Co. V, L.L.C. 35,415 6.0400 1,417 151.0000 213,907 116 99.5 -73,014 -34.13
2014-08-14 TRVN Polaris Venture Management Co. V, L.L.C. 690 6.0400 28 151.0000 4,168
2014-08-14 TRVN Polaris Venture Management Co. V, L.L.C. 243 6.0400 10 151.0000 1,468
2014-08-14 TRVN Polaris Venture Management Co. V, L.L.C. 354 6.0400 14 151.0000 2,138
2014-08-13 TRVN Polaris Venture Management Co. V, L.L.C. 5,500 6.1200 220 153.0000 33,660
2014-08-13 TRVN Polaris Venture Management Co. V, L.L.C. 107 6.1200 4 153.0000 655
2014-08-13 TRVN Polaris Venture Management Co. V, L.L.C. 38 6.1200 2 153.0000 233
2014-08-13 TRVN Polaris Venture Management Co. V, L.L.C. 55 6.1200 2 153.0000 337

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

TRVN / Trevena, Inc. Insider Trades
歷史內部人交易

該表格顯示了由 Jonathan A Flint 進行的所有內幕交易的完整列表，這些交易已向美國證券交易委員會（SEC）披露。

呈報日期 交易日期 表格 證券代碼 證券 代碼 10b5-1 股份 剩餘股份 %
變化		 每股
股價		 交易
金額		 剩餘
金額
2022-03-30 3 ADGI Adagio Therapeutics, Inc.
Common Stock 		3,120,194
2022-03-30 3 ADGI Adagio Therapeutics, Inc.
Common Stock 		60,814
2022-03-30 3 ADGI Adagio Therapeutics, Inc.
Common Stock 		21,374
2022-03-30 3 ADGI Adagio Therapeutics, Inc.
Common Stock 		31,198
2022-03-30 3 ADGI Adagio Therapeutics, Inc.
Common Stock 		4,800,460
2022-03-30 3 ADGI Adagio Therapeutics, Inc.
Common Stock 		497,660
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Warrants 		X - Other -118 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Warrants 		X - Other -173 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Warrants 		X - Other -337 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Warrants 		X - Other -17,304 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series C Convertible Preferred Stock 		C - Conversion -13,625 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series C Convertible Preferred Stock 		C - Conversion -19,890 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series C Convertible Preferred Stock 		C - Conversion -38,765 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series C Convertible Preferred Stock 		C - Conversion -1,988,991 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series B Convertible Preferred Stock 		C - Conversion -43,966 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series B Convertible Preferred Stock 		C - Conversion -64,183 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series B Convertible Preferred Stock 		C - Conversion -125,094 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series B Convertible Preferred Stock 		C - Conversion -6,418,387 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-4 Convertible Preferred Stock 		C - Conversion -52,700 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-4 Convertible Preferred Stock 		C - Conversion -76,934 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-4 Convertible Preferred Stock 		C - Conversion -149,944 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-4 Convertible Preferred Stock 		C - Conversion -7,693,406 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-3 Convertible Preferred Stock 		C - Conversion -58,980 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-3 Convertible Preferred Stock 		C - Conversion -86,101 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-3 Convertible Preferred Stock 		C - Conversion -167,809 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-3 Convertible Preferred Stock 		C - Conversion -8,610,081 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -22,580 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -32,961 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -64,237 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -3,296,014 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-1/C Convertible Preferred Stock 		C - Conversion -42,941 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-1/C Convertible Preferred Stock 		C - Conversion -62,687 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-1/C Convertible Preferred Stock 		C - Conversion -122,177 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Series A-1/C Convertible Preferred Stock 		C - Conversion -6,268,687 0 -100.00
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		P - Purchase 413 7,274 6.02 16.00 6,608 116,384
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		P - Purchase 603 10,618 6.02 16.00 9,648 169,888
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		P - Purchase 1,176 20,701 6.02 16.00 18,816 331,216
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		P - Purchase 60,308 1,062,259 6.02 16.00 964,928 16,996,144
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		S - Sale -64 6,861 -0.92 16.00 -1,024 109,776
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		X - Other 118 6,925 1.73 8.63 1,018 59,763
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		S - Sale -94 10,015 -0.93 16.00 -1,504 160,240
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		X - Other 173 10,109 1.74 8.63 1,493 87,241
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		S - Sale -182 19,525 -0.92 16.00 -2,912 312,400
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		X - Other 337 19,707 1.74 8.63 2,908 170,071
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		S - Sale -9,334 1,001,951 -0.92 16.00 -149,344 16,031,216
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		X - Other 17,304 1,011,285 1.74 8.63 149,334 8,727,390
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		C - Conversion 6,807 6,807
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		C - Conversion 9,936 9,936
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		C - Conversion 19,370 19,370
2020-05-06 2020-05-05 4 LYRA Lyra Therapeutics, Inc.
Common Stock 		C - Conversion 993,981 993,981
2019-12-18 2019-12-17 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -3,446 31,015 -10.00 24.48 -84,355 759,216
2019-12-18 2019-12-17 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -2,360 21,245 -10.00 24.48 -57,770 520,056
2019-12-18 2019-12-17 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -6,716 60,446 -10.00 24.48 -164,401 1,479,658
2019-12-18 2019-12-17 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -344,599 3,101,386 -10.00 24.48 -8,435,439 75,918,828
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Junior Convertible Preferred Stock 		C - Conversion -84,134 0 -100.00
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Junior Convertible Preferred Stock 		C - Conversion -57,631 0 -100.00
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Junior Convertible Preferred Stock 		C - Conversion -163,973 0 -100.00
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Junior Convertible Preferred Stock 		C - Conversion -8,413,256 0 -100.00
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -3,828 34,461 -10.00 18.00 -68,904 620,298
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -2,622 23,605 -10.00 18.00 -47,196 424,890
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -7,462 67,162 -10.00 18.00 -134,316 1,208,916
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		S - Sale -382,887 3,445,985 -10.00 18.00 -6,891,966 62,027,730
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		C - Conversion 38,289 38,289
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		C - Conversion 26,227 26,227
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		C - Conversion 74,624 74,624
2019-07-24 2019-07-22 4 PHR Phreesia, Inc.
Common Stock 		C - Conversion 3,828,872 3,828,872
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series A Warrant (right to buy) 		P - Purchase 7,700 7,700
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series B Warrant (right to buy) 		P - Purchase 7,700 7,700
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series A Warrant (right to buy) 		P - Purchase 5,275 5,275
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series B Warrant (right to buy) 		P - Purchase 5,275 5,275
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series A Warrant (right to buy) 		P - Purchase 15,007 15,007
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series B Warrant (right to buy) 		P - Purchase 15,007 15,007
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series A Warrant (right to buy) 		P - Purchase 769,989 769,989
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series B Warrant (right to buy) 		P - Purchase 769,989 769,989
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series A Warrant (right to buy) 		P - Purchase 6,478 6,478
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series B Warrant (right to buy) 		P - Purchase 6,478 6,478
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series A Warrant (right to buy) 		P - Purchase 345,551 345,551
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Series B Warrant (right to buy) 		P - Purchase 345,551 345,551
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 7,700 34,587 28.64
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 5,275 23,875 28.36
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 15,007 67,729 28.46
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 769,989 3,468,190 28.54
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 6,478 29,178 28.54
2018-04-05 2018-04-03 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 345,551 1,556,676 28.53
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series D Convertible Preferred Stock 		C - Conversion -21,537 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series D Convertible Preferred Stock 		C - Conversion -14,752 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series D Convertible Preferred Stock 		C - Conversion -41,976 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series D Convertible Preferred Stock 		C - Conversion -2,153,746 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series C Convertible Preferred Stock 		C - Conversion -2,213 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series C Convertible Preferred Stock 		C - Conversion -1,516 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series C Convertible Preferred Stock 		C - Conversion -4,315 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series C Convertible Preferred Stock 		C - Conversion -221,638 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series B Convertible Preferred Stock 		C - Conversion -7,108 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series B Convertible Preferred Stock 		C - Conversion -4,869 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series B Convertible Preferred Stock 		C - Conversion -13,854 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series B Convertible Preferred Stock 		C - Conversion -710,817 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -6,801 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -4,659 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -13,256 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-2 Convertible Preferred Stock 		C - Conversion -680,130 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-1 Convertible Preferred Stock 		C - Conversion -643 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-1 Convertible Preferred Stock 		C - Conversion -441 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-1 Convertible Preferred Stock 		C - Conversion -1,254 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Series A-1 Convertible Preferred Stock 		C - Conversion -64,329 0 -100.00
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		P - Purchase 4,825 18,031 36.54 10.00 48,250 180,310
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		P - Purchase 3,305 12,351 36.54 10.00 33,050 123,510
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		P - Purchase 9,403 35,146 36.53 10.00 94,030 351,460
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		P - Purchase 482,467 1,803,429 36.52 10.00 4,824,670 18,034,290
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 6,310 13,206 91.50
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 4,322 9,046 91.49
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 12,298 25,743 91.47
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 631,041 1,320,962 91.47
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 1,102 6,896 19.02
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 755 4,724 19.02
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 2,150 13,445 19.03
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 110,312 689,921 19.03
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 3,173 5,794 121.06
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 2,173 3,969 120.99
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 6,185 11,295 121.04
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 317,376 579,609 121.03
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 2,433 2,621 1,294.15
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 1,667 1,796 1,292.25
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 4,743 5,110 1,292.37
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 243,385 262,233 1,291.30
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 188 188
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 129 129
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 367 367
2017-11-20 2017-11-20 4 ASNS Arsanis, Inc.
Common Stock 		C - Conversion 18,848 18,848
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 15,264 15,264
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 7,832 7,832
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 5,365 5,365
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 783,128 783,128
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 6,589 6,589
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 351,448 351,448
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 1,392 52,722 2.71 6.88 9,570 362,464
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 715 26,887 2.73 6.88 4,916 184,848
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 490 18,600 2.71 6.88 3,369 127,875
2015-06-25 2015-06-15 4/A PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 71,439 2,698,201 2.72 6.88 491,143 18,550,132
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Stock Option (Right to Buy) 		A - Award 17,710 17,710
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 15,264 15,264
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 7,832 7,832
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 5,365 5,365
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 783,128 783,128
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 6,589 6,589
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Warrants to Purchase Common Stock 		A - Award 351,448 351,448
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 1,392 52,692 2.71 6.88 9,570 362,258
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		A - Award 51,330 51,330
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 714 26,886 2.73 6.88 4,909 184,841
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		A - Award 26,172 26,172
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 489 18,599 2.70 6.88 3,362 127,868
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		A - Award 18,110 18,110
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 71,438 2,698,200 2.72 6.88 491,136 18,550,125
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		A - Award 2,626,762 2,626,762
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 601 22,700 2.72 6.88 4,132 156,062
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		A - Award 22,099 22,099
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		P - Purchase 32,059 1,211,125 2.72 6.88 220,406 8,326,484
2015-06-17 2015-06-15 4 PULM Pulmatrix, Inc.
Common Stock 		A - Award 1,179,066 1,179,066
2014-08-18 2014-08-14 4 TRVN TREVENA INC
Common Stock 		S - Sale -354 36,369 -0.96 6.04 -2,138 219,669
2014-08-18 2014-08-14 4 TRVN TREVENA INC
Common Stock 		S - Sale -243 24,911 -0.97 6.04 -1,468 150,462
2014-08-18 2014-08-14 4 TRVN TREVENA INC
Common Stock 		S - Sale -690 70,885 -0.96 6.04 -4,168 428,145
2014-08-18 2014-08-14 4 TRVN TREVENA INC
Common Stock 		S - Sale -35,415 3,637,115 -0.96 6.04 -213,907 21,968,175
2014-08-15 2014-08-13 4 TRVN TREVENA INC
Common Stock 		S - Sale -55 36,723 -0.15 6.12 -337 224,745
2014-08-15 2014-08-13 4 TRVN TREVENA INC
Common Stock 		S - Sale -38 25,154 -0.15 6.12 -233 153,942
2014-08-15 2014-08-13 4 TRVN TREVENA INC
Common Stock 		S - Sale -107 71,575 -0.15 6.12 -655 438,039
2014-08-15 2014-08-13 4 TRVN TREVENA INC
Common Stock 		S - Sale -5,500 3,672,530 -0.15 6.12 -33,660 22,475,884
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Series C Preferred Stock 		C - Conversion -4,840,686 0 -100.00
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Series B-1 Preferred Stock 		C - Conversion -1,462,868 0 -100.00
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Series B-1 Preferred Stock 		S - Sale -487,132 62,868 -88.57 1.13 -549,972 70,978
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Series B-1 Preferred Stock 		X - Other 550,000 550,000 1.00 550,000 550,000
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Warrants- Purchase Series B-1 Preferred Stock (right to buy) 		X - Other -550,000 0 -100.00
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Series B Preferred Stock 		C - Conversion -8,400,000 0 -100.00
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Series A Preferred Stock 		C - Conversion -6,000,000 0 -100.00
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Common Stock 		P - Purchase 472,405 3,811,682 14.15 7.00 3,306,835 26,681,774
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Common Stock 		C - Conversion 780,754 3,339,277 30.52
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Common Stock 		C - Conversion 235,946 2,558,523 10.16
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Common Stock 		C - Conversion 1,354,837 2,322,577 140.00
2014-02-07 2014-02-05 4 TRVN TREVENA INC
Common Stock 		C - Conversion 967,740 967,740
2014-01-30 3 TRVN TREVENA INC
Common Stock 		0
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Series D Preferred Stock 		C - Conversion -964,798 0 -100.00
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Series C-1 Preferred Stock 		C - Conversion -390,170 0 -100.00
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Series C Preferred Stock 		C - Conversion -487,780 0 -100.00
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Series B Preferred Stock 		C - Conversion -1,900,000 0 -100.00
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Series A Preferred Stock 		C - Conversion -1,476,960 0 -100.00
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Common Stock 		P - Purchase 26,000 2,018,253 1.31 15.00 390,000 30,273,795
2013-09-27 2013-09-25 4 BIND BIND Therapeutics, Inc
Common Stock 		C - Conversion 1,992,253 1,992,253
2013-07-19 2013-07-17 4 ALIM ALIMERA SCIENCES INC
Common Stock 		S - Sale -120,664 3,090,769 -3.76 4.80 -579,646 14,847,436
2013-07-19 2013-07-17 4 ALIM ALIMERA SCIENCES INC
Common Stock 		S - Sale -2,273 57,586 -3.80 4.80 -10,919 276,632
2013-06-19 2013-06-18 4 ALIM ALIMERA SCIENCES INC
Common Stock 		S - Sale -16,630 3,211,433 -0.52 5.46 -90,823 17,538,920
2013-06-19 2013-06-18 4 ALIM ALIMERA SCIENCES INC
Common Stock 		S - Sale -313 59,859 -0.52 5.46 -1,709 326,914
2013-06-19 2013-06-17 4 ALIM ALIMERA SCIENCES INC
Common Stock 		S - Sale -19,748 3,228,063 -0.61 5.42 -107,054 17,499,330
2013-06-19 2013-06-17 4 ALIM ALIMERA SCIENCES INC
Common Stock 		S - Sale -372 60,172 -0.61 5.42 -2,017 326,192
2005-02-24 2004-12-16 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -104 37,074 -0.28 6.75 -702 250,250
2005-02-24 2004-12-16 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -6,724 2,351,376 -0.29 6.75 -45,387 15,871,788
2005-02-24 2004-12-16 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -172 61,080 -0.28 6.75 -1,161 412,290
2005-02-04 2005-02-02 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,268 30,384 -4.01 7.41 -9,396 225,145
2005-02-04 2005-02-02 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -81,647 1,938,532 -4.04 7.41 -605,004 14,364,522
2005-02-04 2005-02-02 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -2,085 50,076 -4.00 7.41 -15,450 371,063
2005-02-02 2005-02-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -596 31,652 -1.85 7.18 -4,279 227,261
2005-02-02 2005-02-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -38,422 2,020,179 -1.87 7.18 -275,870 14,504,885
2005-02-02 2005-02-01 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -982 52,161 -1.85 7.18 -7,051 374,516
2005-02-02 2005-01-31 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -358 32,248 -1.10 7.00 -2,506 225,736
2005-02-02 2005-01-31 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -23,053 2,058,601 -1.11 7.00 -161,371 14,410,207
2005-02-02 2005-01-31 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -589 53,143 -1.10 7.00 -4,123 372,001
2005-01-27 2005-01-26 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -298 32,606 -0.91 7.09 -2,113 231,177
2005-01-27 2005-01-26 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -19,211 2,081,654 -0.91 7.09 -136,206 14,758,927
2005-01-27 2005-01-26 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -491 53,732 -0.91 7.09 -3,481 380,960
2005-01-27 2005-01-25 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -298 32,904 -0.90 7.16 -2,134 235,593
2005-01-27 2005-01-25 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -19,211 2,100,865 -0.91 7.16 -137,551 15,042,193
2005-01-27 2005-01-25 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -491 54,223 -0.90 7.16 -3,516 388,237
2005-01-25 2005-01-21 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -339 33,202 -1.01 7.58 -2,570 251,671
2005-01-25 2005-01-21 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -21,898 2,102,111 -1.03 7.58 -165,987 15,934,001
2005-01-25 2005-01-21 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -562 54,714 -1.02 7.58 -4,260 414,732
2005-01-21 2005-01-20 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -127 33,541 -0.38 7.63 -969 255,918
2005-01-21 2005-01-20 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -8,165 2,124,009 -0.38 7.63 -62,299 16,206,189
2005-01-21 2005-01-20 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -208 55,276 -0.37 7.63 -1,587 421,756
2005-01-21 2005-01-19 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -746 33,668 -2.17 7.74 -5,774 260,590
2005-01-21 2005-01-19 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -48,028 2,132,174 -2.20 7.74 -371,737 16,503,027
2005-01-21 2005-01-19 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,226 55,484 -2.16 7.74 -9,489 429,446
2005-01-19 2005-01-18 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -164 34,414 -0.47 8.54 -1,401 293,896
2005-01-19 2005-01-18 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -10,566 2,180,202 -0.48 8.54 -90,234 18,618,925
2005-01-19 2005-01-18 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -270 56,710 -0.47 8.54 -2,306 484,303
2005-01-19 2005-01-14 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -205 34,578 -0.59 8.77 -1,798 303,249
2005-01-19 2005-01-14 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -13,160 2,190,768 -0.60 8.77 -115,413 19,213,035
2005-01-19 2005-01-14 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -335 56,980 -0.58 8.77 -2,938 499,715
2005-01-10 2005-01-06 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -373 34,783 -1.06 8.30 -3,096 288,699
2005-01-10 2005-01-06 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -24,014 2,203,928 -1.08 8.30 -199,316 18,292,602
2005-01-10 2005-01-06 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -613 57,315 -1.06 8.30 -5,088 475,714
2005-01-06 2005-01-04 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -694 35,156 -1.94 7.68 -5,330 269,998
2005-01-06 2005-01-04 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -44,665 2,227,942 -1.97 7.68 -343,027 17,110,595
2005-01-06 2005-01-04 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,141 57,928 -1.93 7.68 -8,763 444,887
2005-01-04 2005-01-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -746 35,850 -2.04 7.63 -5,692 273,536
2005-01-04 2005-01-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -48,028 2,272,607 -2.07 7.63 -366,454 17,339,991
2005-01-04 2005-01-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,226 59,069 -2.03 7.63 -9,354 450,696
2004-12-30 2004-12-29 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -90 36,596 -0.25 7.56 -680 276,666
2004-12-30 2004-12-29 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -5,764 2,320,635 -0.25 7.56 -43,576 17,544,001
2004-12-30 2004-12-29 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -147 60,295 -0.24 7.56 -1,111 455,830
2004-12-30 2004-12-28 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -97 36,686 -0.26 7.56 -733 277,346
2004-12-30 2004-12-28 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -6,244 2,326,399 -0.27 7.56 -47,205 17,587,576
2004-12-30 2004-12-28 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -159 60,442 -0.26 7.56 -1,202 456,942
2004-12-21 2004-12-17 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -395 36,783 -1.06 6.69 -2,644 246,189
2004-12-21 2004-12-17 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -25,455 2,332,643 -1.08 6.69 -170,370 15,612,380
2004-12-21 2004-12-17 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -650 60,601 -1.06 6.69 -4,350 405,602
2004-12-21 2004-12-10 4/A ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -552 39,662 -1.37 6.76 -3,730 267,996
2004-12-21 2004-12-10 4/A ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -35,540 2,518,030 -1.39 6.76 -240,144 17,014,329
2004-12-21 2004-12-10 4/A ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -908 65,335 -1.37 6.76 -6,135 441,469
2004-12-21 2004-12-14 4/A ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -2,484 37,178 -6.26 6.52 -16,188 242,289
2004-12-21 2004-12-14 4/A ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -159,932 2,358,098 -6.35 6.52 -1,042,277 15,367,725
2004-12-21 2004-12-14 4/A ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -4,084 61,251 -6.25 6.52 -26,615 399,173
2004-12-16 2004-12-14 4 ALNY POLARIS INDUSTRIES INC/MN
Common Stock 		S - Sale -2,484 37,178 -6.26 6.52 -16,188 242,289
2004-12-16 2004-12-14 4 ALNY POLARIS INDUSTRIES INC/MN
Common Stock 		S - Sale -159,932 2,358,098 -6.35 6.52 -1,042,277 15,367,725
2004-12-16 2004-12-14 4 ALNY POLARIS INDUSTRIES INC/MN
Common Stock 		S - Sale -4,084 61,251 -6.25 6.52 -26,615 399,173
2004-12-14 2004-12-10 4 ALNY POLARIS INDUSTRIES INC/MN
Common Stock 		S - Sale -552 39,662 -1.37 6.76 -3,730 267,996
2004-12-14 2004-12-10 4 ALNY POLARIS INDUSTRIES INC/MN
Common Stock 		S - Sale -35,540 2,518,030 -1.39 6.76 -240,144 17,014,329
2004-12-14 2004-12-10 4 ALNY POLARIS INDUSTRIES INC/MN
Common Stock 		S - Sale -908 65,335 -1.37 6.76 -6,135 441,469
2004-12-10 2004-12-09 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -589 40,214 -1.44 6.85 -4,037 275,627
2004-12-10 2004-12-09 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -37,942 2,553,570 -1.46 6.85 -260,054 17,502,169
2004-12-10 2004-12-09 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -969 66,243 -1.44 6.85 -6,642 454,030
2004-12-10 2004-12-08 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -351 40,803 -0.85 6.93 -2,431 282,642
2004-12-10 2004-12-08 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -22,573 2,591,512 -0.86 6.93 -156,363 17,951,404
2004-12-10 2004-12-08 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -576 67,212 -0.85 6.93 -3,990 465,578
2004-12-07 2004-12-07 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -312 41,154 -0.75 7.00 -2,183 287,996
2004-12-07 2004-12-07 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -21,179 2,614,085 -0.80 7.00 -148,211 18,293,367
2004-12-07 2004-12-07 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -509 67,788 -0.75 7.00 -3,562 474,380
2004-12-07 2004-12-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,180 41,466 -2.77 6.74 -7,957 279,605
2004-12-07 2004-12-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -74,876 2,635,264 -2.76 6.74 -504,889 17,769,585
2004-12-07 2004-12-03 4 ALNY ALNYLAM PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,944 68,297 -2.77 6.74 -13,108 460,527
P
非衍生或衍生證券的公開市場或私下買入
S
非衍生或衍生證券的公開市場或私下賣出
A
公司向內部人員授予、獎勵或以其他方式獲取證券（例如股票期權）
C
衍生工具轉換
D
將證券賣出或轉讓回公司
F
使用從公司收到的證券的一部分來支付行使價或稅務負擔。
G
內部人士贈送或接收他人贈送公司股票
K
股權掉期和類似的避險交易
M
行使或轉換從公司獲得的衍生證券（例如期權）
V
內部人士透過Form 4自願報告的一筆交易
J
其他（附有交易描述的腳註）