阿卡迪亞製藥公司
US ˙ NasdaqGS ˙ US0042251084

簡介

本頁面提供了有關 Felix Baker 已知的內部交易歷史的全面分析。內部人士包括公司的高管、董事或重要投資者。一般而言，基於內幕、非公開信息進行交易是非法的。這並不意味著他們在自己的公司進行任何交易都是非法的。但是，他們必須透過Form 4向美國證券交易委員會（SEC）報告所有交易。盡管存在這些限制，學術研究表明，內部人士 - 整體而言 - 在自己公司中的投資表現往往優於市場。

平均交易盈利能力

「平均交易盈利能力」衡量了內部人士在過去三年中所有非計劃性的公開市場購買交易的平均回報率。計算過程包括檢查每筆交易，排除了作為10b5-1交易計劃的一部分的交易。然後，對每筆交易在3、6和12個月的表現進行平均，以生成該筆交易最終的表現指標。最終，將所有交易的表現指標進行平均，計算出內部人士的總體平均表現指標。列表僅包含在過去兩年中進行過至少三筆交易的內部人士。

如果內部人士的交易盈利能力顯示為"N/A"，則可能是因為該內部人士在過去三年內沒有進行任何公開市場購買交易，或者他們進行的交易距離現在太近，無法計算出可靠的表現指標。

更新頻率：每日

查看收益最高的的內幕交易者列表。

查看排名最高的內部人士。
報告內部持倉的公司

SEC文件顯示Felix Baker已報告在以下公司擁有持倉或進行了交易：

證券 職位 最新報告的持倉
US:DNLI / Denali Therapeutics Inc. Director 3,422,366
US:KNSA / Kiniksa Pharmaceuticals International, plc Director 2,744,894
US:ACAD / ACADIA Pharmaceuticals Inc. Director, 10% Owner 39,384,587
US:ONC / BeOne Medicines AG - Depositary Receipt (Common Stock) Director 142,570
US:INCY / Incyte Corporation Director, 10% Owner 28,203,718
US:BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock) Director, 10% Owner 10,018,674
US:KOD / Kodiak Sciences Inc. Director, 10% Owner 18,358,772
US:KYMR / Kymera Therapeutics, Inc. Director, 10% Owner 7,955,916
US:TRDA / Entrada Therapeutics, Inc. 10% Owner 4,691,392
US:KALA / KALA BIO, Inc. 425,006
US:CELC / Celcuity Inc. 10% Owner 7,211,484
US:VTVT / vTv Therapeutics Inc. Director 135,946
US:MDGL / Madrigal Pharmaceuticals, Inc. Director 1,859,091
US:IGMS / IGM Biosciences, Inc. 0
US:IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock) Director 2,144,060
US:REPL / Replimune Group, Inc. Director, 10% Owner 929,241
US:SERA / Sera Prognostics, Inc. 10% Owner 432,434
US:SGEN / Seagen Inc Director 0
US:BLCM / Bellicum Pharmaceuticals, Inc. 10% Owner 2,168,818
US:BCEL / Atreca, Inc. 2,971,128
US:NLTX / Neoleukin Therapeutics, Inc. Director, 10% Owner 1,658,190
US:DBVT / DBV Technologies S.A. - Depositary Receipt (Common Stock) Director, 10% Owner 14,575,984
US:TCRX / TScan Therapeutics, Inc. Director, 10% Owner 2,528,583
US:TLIS / Talis Biomedical Corporation Director, 10% Owner 7,053,176
US:PRLD / Prelude Therapeutics Incorporated Director, 10% Owner 23,344
US:AGLE / Aeglea BioTherapeutics Inc Director 40,000
US:US00C4W3Z001 / Alexion Pharmaceuticals, Inc. Director 7,846,213
US:ZYME / Zymeworks Inc. Director 9,000
US:GHDX / Genomic Health, Inc. Director, 10% Owner 7,642,042
US:IDRA / Idera Pharmaceuticals, Inc. 10% Owner 4,290,995
US:HOOK / HOOKIPA Pharma Inc. 529,758
US:NVTA / Invitae Corporation 10% Owner 7,480,182
US:MRTX / Mirati Therapeutics, Inc. 1,618,684
US:RYTM / Rhythm Pharmaceuticals, Inc. 0
US:BCRX / BioCryst Pharmaceuticals, Inc. 10% Owner 9,418,390
US:NTLA / Intellia Therapeutics, Inc. 0
US:XOMA / XOMA Royalty Corporation 90,538
US:GEVA / Synageva Biopharma Corp 0
US:RDEA / Ardea Biosciences, Inc. Director, 10% Owner 0
US:TZYM / 10% Owner 57,704
US:PCYC / Pharmacyclics 10% Owner 557,211
US:DDXS / Diadexus, Inc. 10% Owner 0
US:ADLR / Adolor Corp 10% Owner 0
如何解讀這些圖表

以下圖表顯示了在Felix Baker進行的每筆公開市場非計劃交易後證券的股價表現。非計劃交易是指沒有作為10b5-1交易計劃的一部分而進行的交易。股價表現以累積百分比變化的方式繪製。例如，如果一筆內部人士交易是在2019年1月1日進行的，該圖表將顯示該證券的每日百分比變化直至當前日期。如果在此期間股價從10美元漲至15美元，則股價的累積百分比變化將為50%。從10美元漲至20美元的價格變化將為100%，而從10美元跌至5美元的價格變化將為-50%。

最終，我們將評估內部人士的交易與股價的超額回報（正向或負向）之間的相關性，以判斷內部人士是否在交易中利用內部信息獲利。如果內部人士有這樣的行為，我們預期看到（a）購買後的正回報，或者（b）賣出後的負回報。對於情況（a），購買圖表將顯示一系列向上傾斜的曲線，表示每次購買後都有正回報。對於情況（b），賣出圖表將顯示一系列向下傾斜的曲線，表示每次賣出後都有負回報。

然而，僅憑這一點還不足以得出結論。例如，如果公司的股價在多年內呈現非周期性上升，我們會預期所有購買後的圖表都呈現向上傾斜。同樣地，多年來呈現非周期性下降的股價會導致賣出後的圖表也呈現向下傾斜。這兩種情況的圖表都不能表示內部人士在進行內幕交易。

最有力的指標是在公司股價呈極度循環波動的情況下，「購買」圖表顯示正向信號，而「賣出」圖表顯示負向趨勢。這種情況強烈暗示內部人士可能根據內幕信息精確地計時進行交易，以獲得財務優勢。

ACAD / ACADIA Pharmaceuticals Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2023-05-24 ACAD BAKER BROS. ADVISORS LP 20,304 25.2723 20,304 25.2723 513,129 54 33.4650 166,345 32.42
2023-05-24 ACAD BAKER BROS. ADVISORS LP 218,171 25.2723 218,171 25.2723 5,513,683
2023-05-24 ACAD BAKER BROS. ADVISORS LP 2,688 25.5138 2,688 25.5138 68,581
2023-05-24 ACAD BAKER BROS. ADVISORS LP 28,878 25.5138 28,878 25.5138 736,788
2023-05-24 ACAD BAKER BROS. ADVISORS LP 24,113 25.6500 24,113 25.6500 618,498
2023-05-24 ACAD BAKER BROS. ADVISORS LP 259,109 25.6500 259,109 25.6500 6,646,146
2023-05-23 ACAD BAKER BROS. ADVISORS LP 10,858 25.3302 10,858 25.3302 275,035
2023-05-23 ACAD BAKER BROS. ADVISORS LP 116,672 25.3302 116,672 25.3302 2,955,325
2023-05-23 ACAD BAKER BROS. ADVISORS LP 6,941 25.5400 6,941 25.5400 177,273
2023-05-23 ACAD BAKER BROS. ADVISORS LP 74,582 25.5400 74,582 25.5400 1,904,824
2023-05-22 ACAD BAKER BROS. ADVISORS LP 7,645 24.4604 7,645 24.4604 187,000
2023-05-22 ACAD BAKER BROS. ADVISORS LP 82,148 24.4604 82,148 24.4604 2,009,373
2023-05-22 ACAD BAKER BROS. ADVISORS LP 3,781 24.8000 3,781 24.8000 93,769
2023-05-22 ACAD BAKER BROS. ADVISORS LP 40,632 24.8000 40,632 24.8000 1,007,674
2020-03-18 ACAD BAKER BROS. ADVISORS LP 25 31.9350 25 31.9350 798
2020-03-18 ACAD BAKER BROS. ADVISORS LP 275 31.9350 275 31.9350 8,782
2020-03-18 ACAD BAKER BROS. ADVISORS LP 4,175 32.6072 4,175 32.6072 136,135
2020-03-18 ACAD BAKER BROS. ADVISORS LP 46,225 32.6072 46,225 32.6072 1,507,268
2020-03-18 ACAD BAKER BROS. ADVISORS LP 199 32.8498 199 32.8498 6,537
2020-03-18 ACAD BAKER BROS. ADVISORS LP 2,201 32.8498 2,201 32.8498 72,302
2020-03-18 ACAD BAKER BROS. ADVISORS LP 3,023 33.6321 3,023 33.6321 101,670
2020-03-18 ACAD BAKER BROS. ADVISORS LP 33,464 33.6321 33,464 33.6321 1,125,465
2020-03-18 ACAD BAKER BROS. ADVISORS LP 3,837 34.4665 3,837 34.4665 132,248
2020-03-18 ACAD BAKER BROS. ADVISORS LP 42,473 34.4665 42,473 34.4665 1,463,896
2020-03-17 ACAD BAKER BROS. ADVISORS LP 353 30.9955 353 30.9955 10,941
2020-03-17 ACAD BAKER BROS. ADVISORS LP 3,913 30.9955 3,913 30.9955 121,285
2020-03-17 ACAD BAKER BROS. ADVISORS LP 3,903 31.7356 3,903 31.7356 123,864
2020-03-17 ACAD BAKER BROS. ADVISORS LP 43,212 31.7356 43,212 31.7356 1,371,359
2020-03-17 ACAD BAKER BROS. ADVISORS LP 688 31.8300 688 31.8300 21,899
2020-03-17 ACAD BAKER BROS. ADVISORS LP 7,612 31.8300 7,612 31.8300 242,290
2020-03-17 ACAD BAKER BROS. ADVISORS LP 2,676 32.1908 2,676 32.1908 86,143
2020-03-17 ACAD BAKER BROS. ADVISORS LP 29,624 32.1908 29,624 32.1908 953,620
2020-03-17 ACAD BAKER BROS. ADVISORS LP 2,188 32.3194 2,188 32.3194 70,715
2020-03-17 ACAD BAKER BROS. ADVISORS LP 24,223 32.3194 24,223 32.3194 782,873
2020-03-17 ACAD BAKER BROS. ADVISORS LP 8,402 33.8624 8,402 33.8624 284,512
2020-03-17 ACAD BAKER BROS. ADVISORS LP 93,006 33.8624 93,006 33.8624 3,149,406
2020-03-16 ACAD BAKER BROS. ADVISORS LP 497 31.1853 497 31.1853 15,499
2020-03-16 ACAD BAKER BROS. ADVISORS LP 5,503 31.1853 5,503 31.1853 171,613
2020-03-16 ACAD BAKER BROS. ADVISORS LP 57,022 31.5136 57,022 31.5136 1,796,968
2020-03-16 ACAD BAKER BROS. ADVISORS LP 631,281 31.5136 631,281 31.5136 19,893,937
2019-09-20 ACAD BAKER BROS. ADVISORS LP 68,475 40.0000 68,475 40.0000 2,739,000
2019-09-20 ACAD BAKER BROS. ADVISORS LP 1,494,025 40.0000 1,494,025 40.0000 59,761,000
2018-11-30 ACAD BAKER BROS. ADVISORS LP 585,882 17.0000 585,882 17.0000 9,959,994
2018-11-30 ACAD BAKER BROS. ADVISORS LP 11,178,823 17.0000 11,178,823 17.0000 190,039,991
2018-09-20 ACAD BAKER BROS. ADVISORS LP 102,267 18.6366 102,267 18.6366 1,905,909
2018-09-20 ACAD BAKER BROS. ADVISORS LP 920,495 18.6366 920,495 18.6366 17,154,897
2018-09-20 ACAD BAKER BROS. ADVISORS LP 4,245 19.0110 4,245 19.0110 80,702
2018-09-20 ACAD BAKER BROS. ADVISORS LP 38,207 19.0110 38,207 19.0110 726,353
2018-09-20 ACAD BAKER BROS. ADVISORS LP 14,555 19.0924 14,555 19.0924 277,890
2018-09-20 ACAD BAKER BROS. ADVISORS LP 131,007 19.0924 131,007 19.0924 2,501,238
2016-08-10 ACAD BAKER BROS. ADVISORS LP 133,153 33.0000 133,153 33.0000 4,394,049
2016-08-10 ACAD BAKER BROS. ADVISORS LP 1,169,877 33.0000 1,169,877 33.0000 38,605,941
2016-04-01 ACAD BAKER BROS. ADVISORS LP 1,182 27.8202 1,182 27.8202 32,883
2016-04-01 ACAD BAKER BROS. ADVISORS LP 10,818 27.8202 10,818 27.8202 300,959
2016-04-01 ACAD BAKER BROS. ADVISORS LP 28,647 28.5484 28,647 28.5484 817,826
2016-04-01 ACAD BAKER BROS. ADVISORS LP 262,253 28.5484 262,253 28.5484 7,486,904
2016-03-31 ACAD BAKER BROS. ADVISORS LP 1,614 25.6070 1,614 25.6070 41,330
2016-03-31 ACAD BAKER BROS. ADVISORS LP 14,775 25.6070 14,775 25.6070 378,343
2016-03-31 ACAD BAKER BROS. ADVISORS LP 1,467 26.2850 1,467 26.2850 38,560
2016-03-31 ACAD BAKER BROS. ADVISORS LP 13,433 26.2850 13,433 26.2850 353,086
2016-03-31 ACAD BAKER BROS. ADVISORS LP 19,676 26.4944 19,676 26.4944 521,304
2016-03-31 ACAD BAKER BROS. ADVISORS LP 180,122 26.4944 180,122 26.4944 4,772,224
2016-03-31 ACAD BAKER BROS. ADVISORS LP 3,106 26.5545 3,106 26.5545 82,478
2016-03-31 ACAD BAKER BROS. ADVISORS LP 28,433 26.5545 28,433 26.5545 755,024
2016-03-31 ACAD BAKER BROS. ADVISORS LP 6,618 27.5588 6,618 27.5588 182,384
2016-03-31 ACAD BAKER BROS. ADVISORS LP 60,587 27.5588 60,587 27.5588 1,669,705
2016-03-31 ACAD BAKER BROS. ADVISORS LP 34,844 27.7173 34,844 27.7173 965,782
2016-03-31 ACAD BAKER BROS. ADVISORS LP 318,969 27.7173 318,969 27.7173 8,840,959
2016-03-30 ACAD BAKER BROS. ADVISORS LP 408,607 25.9247 408,607 25.9247 10,593,014
2016-03-30 ACAD BAKER BROS. ADVISORS LP 37,882 25.9750 37,882 25.9750 983,985
2016-03-30 ACAD BAKER BROS. ADVISORS LP 16,057 26.3472 16,057 26.3472 423,057
2016-01-07 ACAD BAKER BROS. ADVISORS LP 785,045 29.0000 785,045 29.0000 22,766,305
2016-01-07 ACAD BAKER BROS. ADVISORS LP 1,801,161 29.0000 1,801,161 29.0000 52,233,669
2014-03-05 ACAD BAKER BROS. ADVISORS LP 38,934 28.5000 38,934 28.5000 1,109,619
2014-03-05 ACAD BAKER BROS. ADVISORS LP 475,644 28.5000 475,644 28.5000 13,555,854
2014-03-05 ACAD BAKER BROS. ADVISORS LP 11,738 28.5000 11,738 28.5000 334,533
2013-06-05 ACAD BAKER FELIX 26,577 14.4565 26,577 14.4565 384,210
2013-06-05 ACAD BAKER FELIX 217,986 14.4565 217,986 14.4565 3,151,315
2013-06-05 ACAD BAKER FELIX 5,437 14.4565 5,437 14.4565 78,600
2013-06-05 ACAD BAKER FELIX 21,080 14.5838 21,080 14.5838 307,427
2013-06-05 ACAD BAKER FELIX 172,893 14.5838 172,893 14.5838 2,521,437
2013-06-05 ACAD BAKER FELIX 4,312 14.5838 4,312 14.5838 62,885
2013-06-05 ACAD BAKER FELIX 18,530 14.5502 18,530 14.5502 269,615
2013-06-05 ACAD BAKER FELIX 151,980 14.5502 151,980 14.5502 2,211,339
2013-06-05 ACAD BAKER FELIX 3,790 14.5502 3,790 14.5502 55,145
2013-06-05 ACAD BAKER FELIX 26,577 14.4641 26,577 14.4641 384,412
2013-06-05 ACAD BAKER FELIX 217,986 14.4641 217,986 14.4641 3,152,971
2013-06-05 ACAD BAKER FELIX 5,437 14.4641 5,437 14.4641 78,641
2013-06-04 ACAD BAKER FELIX 4,353 14.4977 4,353 14.4977 63,108
2013-06-04 ACAD BAKER FELIX 35,702 14.4977 35,702 14.4977 517,597
2013-06-04 ACAD BAKER FELIX 890 14.4977 890 14.4977 12,903
2013-06-04 ACAD BAKER FELIX 56,475 14.4525 56,475 14.4525 816,205
2013-06-04 ACAD BAKER FELIX 463,197 14.4525 463,197 14.4525 6,694,355
2013-06-04 ACAD BAKER FELIX 11,552 14.4525 11,552 14.4525 166,955
2013-06-04 ACAD BAKER FELIX 13,566 14.4159 13,566 14.4159 195,566
2013-06-04 ACAD BAKER FELIX 111,266 14.4159 111,266 14.4159 1,604,000
2013-06-04 ACAD BAKER FELIX 2,775 14.4159 2,775 14.4159 40,004
2013-06-03 ACAD BAKER FELIX 56,274 14.0822 56,274 14.0822 792,462
2013-06-03 ACAD BAKER FELIX 461,548 14.0822 461,548 14.0822 6,499,611
2013-06-03 ACAD BAKER FELIX 11,511 14.0822 11,511 14.0822 162,100
2013-06-03 ACAD BAKER FELIX 25,368 13.9990 25,368 13.9990 355,127
2013-06-03 ACAD BAKER FELIX 208,063 13.9990 208,063 13.9990 2,912,674
2013-06-03 ACAD BAKER FELIX 5,189 13.9990 5,189 13.9990 72,641
2013-05-15 ACAD BAKER FELIX 218,846 12.5000 218,846 12.5000 2,735,575
2013-05-15 ACAD BAKER FELIX 1,730,970 12.5000 1,730,970 12.5000 21,637,125
2013-05-15 ACAD BAKER FELIX 43,184 12.5000 43,184 12.5000 539,800

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

ACAD / ACADIA Pharmaceuticals Inc. Insider Trades
ACAD / ACADIA Pharmaceuticals Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

ACAD / ACADIA Pharmaceuticals Inc. Insider Trades
BCRX / BioCryst Pharmaceuticals, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2016-02-05 BCRX BAKER BROS. ADVISORS LP 45,000 6.3257 45,000 6.3257 284,656 336 7.13 36,194 12.71
2016-02-04 BCRX BAKER BROS. ADVISORS LP 24,800 6.6498 24,800 6.6498 164,915
2016-02-03 BCRX BAKER BROS. ADVISORS LP 91,187 6.2872 91,187 6.2872 573,311
2016-02-02 BCRX BAKER BROS. ADVISORS LP 91,728 6.5232 91,728 6.5232 598,360
2016-01-28 BCRX BAKER BROS. ADVISORS LP 25,000 6.8806 25,000 6.8806 172,015
2016-01-27 BCRX BAKER BROS. ADVISORS LP 63,345 6.9772 63,345 6.9772 441,971
2016-01-22 BCRX BAKER BROS. ADVISORS LP 3,200 6.9966 3,200 6.9966 22,389
2016-01-21 BCRX BAKER BROS. ADVISORS LP 103,600 7.2912 103,600 7.2912 755,368
2016-01-20 BCRX BAKER BROS. ADVISORS LP 51,370 6.8712 51,370 6.8712 352,974
2016-01-20 BCRX BAKER BROS. ADVISORS LP 1,325 6.9415 1,325 6.9415 9,197
2016-01-19 BCRX BAKER BROS. ADVISORS LP 92,200 7.1231 92,200 7.1231 656,750
2016-01-15 BCRX BAKER BROS. ADVISORS LP 175,000 7.4508 175,000 7.4508 1,303,890
2016-01-15 BCRX BAKER BROS. ADVISORS LP 25,000 7.4933 25,000 7.4933 187,332
2013-08-01 BCRX BAKER FELIX 120,498 4.4000 120,498 4.4000 530,191
2013-08-01 BCRX BAKER FELIX 991,161 4.4000 991,161 4.4000 4,361,108
2013-08-01 BCRX BAKER FELIX 24,705 4.4000 24,705 4.4000 108,702

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

BCRX / BioCryst Pharmaceuticals, Inc. Insider Trades
BCRX / BioCryst Pharmaceuticals, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
2016-08-16 BCRX BAKER BROS. ADVISORS LP 140 4.2887 140 4.2887 600 79 3.76 -74 -12.27
2016-08-16 BCRX BAKER BROS. ADVISORS LP 850 4.2887 850 4.2887 3,645
2016-08-15 BCRX BAKER BROS. ADVISORS LP 56,417 4.8276 56,417 4.8276 272,359
2016-08-15 BCRX BAKER BROS. ADVISORS LP 343,583 4.8276 343,583 4.8276 1,658,681
2016-08-12 BCRX BAKER BROS. ADVISORS LP 465,439 5.0000 465,439 5.0000 2,327,195
2016-08-12 BCRX BAKER BROS. ADVISORS LP 2,834,561 5.0000 2,834,561 5.0000 14,172,805
2016-08-12 BCRX BAKER BROS. ADVISORS LP 48,744 5.2541 48,744 5.2541 256,106
2016-08-12 BCRX BAKER BROS. ADVISORS LP 296,856 5.2541 296,856 5.2541 1,559,711

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

BCRX / BioCryst Pharmaceuticals, Inc. Insider Trades
BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2024-12-16 BCYC BAKER BROS. ADVISORS LP 42,369 15.3418 42,369 15.3418 650,017 2 15.3150 -1,135 -0.17
2024-12-16 BCYC BAKER BROS. ADVISORS LP 457,631 15.3418 457,631 15.3418 7,020,883
2024-12-13 BCYC BAKER BROS. ADVISORS LP 2,809 13.4979 2,809 13.4979 37,916
2024-12-13 BCYC BAKER BROS. ADVISORS LP 30,241 13.4979 30,241 13.4979 408,190
2024-12-13 BCYC BAKER BROS. ADVISORS LP 5,573 13.6288 5,573 13.6288 75,953
2024-12-13 BCYC BAKER BROS. ADVISORS LP 59,995 13.6288 59,995 13.6288 817,660
2024-12-13 BCYC BAKER BROS. ADVISORS LP 22,722 13.7242 22,722 13.7242 311,841
2024-12-13 BCYC BAKER BROS. ADVISORS LP 244,587 13.7242 244,587 13.7242 3,356,761
2024-12-13 BCYC BAKER BROS. ADVISORS LP 52,656 13.8040 52,656 13.8040 726,863
2024-12-13 BCYC BAKER BROS. ADVISORS LP 566,814 13.8040 566,814 13.8040 7,824,300

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock) Insider Trades
BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock) Insider Trades
CELC / Celcuity Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2025-09-08 CELC BAKER BROS. ADVISORS LP 13,976 56.2200 13,976 56.2200 785,731 238 144.9800 1,240,510 157.88
2025-09-08 CELC BAKER BROS. ADVISORS LP 151,524 56.2200 151,524 56.2200 8,518,679
2025-09-08 CELC BAKER BROS. ADVISORS LP 388 58.0236 388 58.0236 22,513
2025-09-08 CELC BAKER BROS. ADVISORS LP 4,212 58.0236 4,212 58.0236 244,395

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

CELC / Celcuity Inc. Insider Trades
CELC / Celcuity Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

CELC / Celcuity Inc. Insider Trades
IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock)內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2025-03-17 IMCR BAKER BROS. ADVISORS LP 60,110 29.7416 60,110 29.7416 1,787,768 262 40.2150 629,557 35.21
2025-03-17 IMCR BAKER BROS. ADVISORS LP 646,290 29.7416 646,290 29.7416 19,221,699
2025-03-17 IMCR BAKER BROS. ADVISORS LP 8,589 29.5603 8,589 29.5603 253,893
2025-03-17 IMCR BAKER BROS. ADVISORS LP 92,349 29.5603 92,349 29.5603 2,729,864

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock) Insider Trades
IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock)內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock) Insider Trades
KALA / KALA BIO, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2024-12-30 KALA BAKER BROS. ADVISORS LP 30,620 6.4400 612 322.0000 197,193 263 19.6300 -185,178 -93.91
2024-12-30 KALA BAKER BROS. ADVISORS LP 279,939 6.4400 5,599 322.0000 1,802,807

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KALA / KALA BIO, Inc. Insider Trades
KALA / KALA BIO, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
2025-10-01 KALA BAKER BROS. ADVISORS LP 50,640 1.3838 1,013 69.1900 70,076 219 0.0793 -69,995 -99.89
2025-10-01 KALA BAKER BROS. ADVISORS LP 462,967 1.3838 9,259 69.1900 640,654
2025-09-30 KALA BAKER BROS. ADVISORS LP 21,376 1.5959 428 79.7950 34,114
2025-09-30 KALA BAKER BROS. ADVISORS LP 195,425 1.5959 3,908 79.7950 311,879

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KALA / KALA BIO, Inc. Insider Trades
KNSA / Kiniksa Pharmaceuticals International, plc內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2018-05-29 KNSA BAKER BROS. ADVISORS LP 299,403 18.0000 299,403 18.0000 5,389,254 114 30.93 3,871,281 71.83
2018-05-29 KNSA BAKER BROS. ADVISORS LP 2,700,597 18.0000 2,700,597 18.0000 48,610,746

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KNSA / Kiniksa Pharmaceuticals International, plc Insider Trades
KNSA / Kiniksa Pharmaceuticals International, plc內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KNSA / Kiniksa Pharmaceuticals International, plc Insider Trades
KOD / Kodiak Sciences Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2025-12-18 KOD BAKER BROS. ADVISORS LP 217,428 23.0000 217,428 23.0000 5,000,844 123 46.4400 5,096,512 101.91
2025-12-18 KOD BAKER BROS. ADVISORS LP 2,391,268 23.0000 2,391,268 23.0000 54,999,164
2022-06-06 KOD BAKER BROS. ADVISORS LP 11,945 7.7488 11,945 7.7488 92,559
2022-06-06 KOD BAKER BROS. ADVISORS LP 101,315 7.7488 101,315 7.7488 785,070
2022-06-06 KOD BAKER BROS. ADVISORS LP 20,108 7.7808 20,108 7.7808 156,456
2022-06-06 KOD BAKER BROS. ADVISORS LP 170,549 7.7808 170,549 7.7808 1,327,008
2022-06-03 KOD BAKER BROS. ADVISORS LP 1,550 7.9333 1,550 7.9333 12,297
2022-06-03 KOD BAKER BROS. ADVISORS LP 13,155 7.9333 13,155 7.9333 104,363
2022-06-03 KOD BAKER BROS. ADVISORS LP 9,224 7.9527 9,224 7.9527 73,356
2022-06-03 KOD BAKER BROS. ADVISORS LP 78,271 7.9527 78,271 7.9527 622,466
2022-06-02 KOD BAKER BROS. ADVISORS LP 1,247 7.5144 1,247 7.5144 9,370
2022-06-02 KOD BAKER BROS. ADVISORS LP 10,585 7.5144 10,585 7.5144 79,540
2022-06-02 KOD BAKER BROS. ADVISORS LP 16,278 7.6793 16,278 7.6793 125,004
2022-06-02 KOD BAKER BROS. ADVISORS LP 138,122 7.6793 138,122 7.6793 1,060,680
2022-05-27 KOD BAKER BROS. ADVISORS LP 42 6.6350 42 6.6350 279
2022-05-27 KOD BAKER BROS. ADVISORS LP 358 6.6350 358 6.6350 2,375
2022-05-27 KOD BAKER BROS. ADVISORS LP 6,026 6.7806 6,026 6.7806 40,860
2022-05-27 KOD BAKER BROS. ADVISORS LP 51,082 6.7806 51,082 6.7806 346,367
2022-05-27 KOD BAKER BROS. ADVISORS LP 10,386 6.9200 10,386 6.9200 71,871
2022-05-27 KOD BAKER BROS. ADVISORS LP 88,046 6.9200 88,046 6.9200 609,278
2022-05-26 KOD BAKER BROS. ADVISORS LP 3,432 6.7064 3,432 6.7064 23,016
2022-05-26 KOD BAKER BROS. ADVISORS LP 29,090 6.7064 29,090 6.7064 195,089
2022-05-26 KOD BAKER BROS. ADVISORS LP 6,299 6.7512 6,299 6.7512 42,526
2022-05-26 KOD BAKER BROS. ADVISORS LP 53,401 6.7512 53,401 6.7512 360,521
2022-05-26 KOD BAKER BROS. ADVISORS LP 116 6.7550 116 6.7550 784
2022-05-26 KOD BAKER BROS. ADVISORS LP 984 6.7550 984 6.7550 6,647
2022-05-25 KOD BAKER BROS. ADVISORS LP 5,688 6.5335 5,688 6.5335 37,163
2022-05-25 KOD BAKER BROS. ADVISORS LP 48,222 6.5335 48,222 6.5335 315,058
2022-05-25 KOD BAKER BROS. ADVISORS LP 4,984 6.6036 4,984 6.6036 32,912
2022-05-25 KOD BAKER BROS. ADVISORS LP 42,250 6.6036 42,250 6.6036 279,002
2022-05-18 KOD BAKER BROS. ADVISORS LP 1,115 5.9537 1,115 5.9537 6,638
2022-05-18 KOD BAKER BROS. ADVISORS LP 9,157 5.9537 9,157 5.9537 54,518
2022-05-18 KOD BAKER BROS. ADVISORS LP 22,266 5.9686 22,266 5.9686 132,897
2022-05-18 KOD BAKER BROS. ADVISORS LP 182,827 5.9686 182,827 5.9686 1,091,221
2022-05-18 KOD BAKER BROS. ADVISORS LP 912 5.9689 912 5.9689 5,444
2022-05-18 KOD BAKER BROS. ADVISORS LP 7,489 5.9689 7,489 5.9689 44,701
2022-05-17 KOD BAKER BROS. ADVISORS LP 989 5.9866 989 5.9866 5,921
2022-05-17 KOD BAKER BROS. ADVISORS LP 8,118 5.9866 8,118 5.9866 48,599
2022-05-17 KOD BAKER BROS. ADVISORS LP 11,043 5.9877 11,043 5.9877 66,122
2022-05-17 KOD BAKER BROS. ADVISORS LP 90,674 5.9877 90,674 5.9877 542,929
2022-05-16 KOD BAKER BROS. ADVISORS LP 11,410 5.7101 11,410 5.7101 65,152
2022-05-16 KOD BAKER BROS. ADVISORS LP 93,690 5.7101 93,690 5.7101 534,979
2022-05-16 KOD BAKER BROS. ADVISORS LP 1,846 5.7475 1,846 5.7475 10,610
2022-05-16 KOD BAKER BROS. ADVISORS LP 15,154 5.7475 15,154 5.7475 87,098
2022-02-17 KOD BAKER BROS. ADVISORS LP 426 53.8186 426 53.8186 22,927
2022-02-17 KOD BAKER BROS. ADVISORS LP 5,174 53.8186 5,174 53.8186 278,457
2022-02-17 KOD BAKER BROS. ADVISORS LP 22,403 54.5737 22,403 54.5737 1,222,615
2022-02-17 KOD BAKER BROS. ADVISORS LP 271,997 54.5737 271,997 54.5737 14,843,883
2022-02-16 KOD BAKER BROS. ADVISORS LP 1,961 53.7325 1,961 53.7325 105,369
2022-02-16 KOD BAKER BROS. ADVISORS LP 23,804 53.7325 23,804 53.7325 1,279,048
2022-02-16 KOD BAKER BROS. ADVISORS LP 5,281 54.2616 5,281 54.2616 286,556
2022-02-16 KOD BAKER BROS. ADVISORS LP 64,119 54.2616 64,119 54.2616 3,479,200
2022-02-15 KOD BAKER BROS. ADVISORS LP 441 54.1550 441 54.1550 23,882
2022-02-15 KOD BAKER BROS. ADVISORS LP 5,359 54.1550 5,359 54.1550 290,217
2022-01-31 KOD BAKER BROS. ADVISORS LP 2,307 57.2205 2,307 57.2205 132,008
2022-01-31 KOD BAKER BROS. ADVISORS LP 27,841 57.2205 27,841 57.2205 1,593,076
2022-01-28 KOD BAKER BROS. ADVISORS LP 1,851 49.7011 1,851 49.7011 91,997
2022-01-28 KOD BAKER BROS. ADVISORS LP 22,395 49.7011 22,395 49.7011 1,113,056
2022-01-28 KOD BAKER BROS. ADVISORS LP 1,414 50.5555 1,414 50.5555 71,485
2022-01-28 KOD BAKER BROS. ADVISORS LP 17,119 50.5555 17,119 50.5555 865,460
2022-01-28 KOD BAKER BROS. ADVISORS LP 953 51.6136 953 51.6136 49,188
2022-01-28 KOD BAKER BROS. ADVISORS LP 11,526 51.6136 11,526 51.6136 594,898
2022-01-27 KOD BAKER BROS. ADVISORS LP 86,479 52.0415 86,479 52.0415 4,500,497
2022-01-27 KOD BAKER BROS. ADVISORS LP 117,291 51.5881 117,291 51.5881 6,050,820
2022-01-27 KOD BAKER BROS. ADVISORS LP 4,465 51.6713 4,465 51.6713 230,712
2022-01-27 KOD BAKER BROS. ADVISORS LP 54,024 51.6713 54,024 51.6713 2,791,490
2022-01-25 KOD BAKER BROS. ADVISORS LP 5,500 58.8971 5,500 58.8971 323,934
2022-01-24 KOD BAKER BROS. ADVISORS LP 19,750 56.3873 19,750 56.3873 1,113,649
2022-01-24 KOD BAKER BROS. ADVISORS LP 1,200 56.5950 1,200 56.5950 67,914
2022-01-24 KOD BAKER BROS. ADVISORS LP 116,083 56.8650 116,083 56.8650 6,601,060
2022-01-24 KOD BAKER BROS. ADVISORS LP 25,900 57.5876 25,900 57.5876 1,491,519
2022-01-24 KOD BAKER BROS. ADVISORS LP 132,367 58.1258 132,367 58.1258 7,693,938
2022-01-24 KOD BAKER BROS. ADVISORS LP 9,350 58.7559 9,350 58.7559 549,368
2022-01-24 KOD BAKER BROS. ADVISORS LP 57,547 58.8709 57,547 58.8709 3,387,844
2022-01-21 KOD BAKER BROS. ADVISORS LP 102,207 56.5742 102,207 56.5742 5,782,279
2022-01-21 KOD BAKER BROS. ADVISORS LP 31,207 57.5285 31,207 57.5285 1,795,292
2021-09-30 KOD BAKER BROS. ADVISORS LP 86,932 95.8286 86,932 95.8286 8,330,572
2021-09-16 KOD BAKER BROS. ADVISORS LP 1,153 94.5918 1,153 94.5918 109,064
2021-09-15 KOD BAKER BROS. ADVISORS LP 30,285 94.3842 30,285 94.3842 2,858,425
2021-09-15 KOD BAKER BROS. ADVISORS LP 400 94.4775 400 94.4775 37,791
2021-09-07 KOD BAKER BROS. ADVISORS LP 5,300 92.8829 5,300 92.8829 492,279
2021-09-07 KOD BAKER BROS. ADVISORS LP 52,201 93.3497 52,201 93.3497 4,872,948
2021-08-19 KOD BAKER BROS. ADVISORS LP 2,968 86.9385 2,968 86.9385 258,033
2021-08-19 KOD BAKER BROS. ADVISORS LP 4,649 87.0710 4,649 87.0710 404,793
2021-08-19 KOD BAKER BROS. ADVISORS LP 2,396 87.4821 2,396 87.4821 209,607
2021-08-19 KOD BAKER BROS. ADVISORS LP 73,635 87.6141 73,635 87.6141 6,451,464
2021-08-18 KOD BAKER BROS. ADVISORS LP 12,898 87.7890 12,898 87.7890 1,132,303
2021-08-18 KOD BAKER BROS. ADVISORS LP 8,186 87.9134 8,186 87.9134 719,659
2021-08-18 KOD BAKER BROS. ADVISORS LP 1,100 88.1650 1,100 88.1650 96,982
2021-08-18 KOD BAKER BROS. ADVISORS LP 400 89.6563 400 89.6563 35,863
2021-08-17 KOD BAKER BROS. ADVISORS LP 400 84.8025 400 84.8025 33,921
2021-08-17 KOD BAKER BROS. ADVISORS LP 7,764 85.9522 7,764 85.9522 667,333
2021-08-13 KOD BAKER BROS. ADVISORS LP 21,595 88.5870 21,595 88.5870 1,913,036
2021-08-13 KOD BAKER BROS. ADVISORS LP 16,269 88.7588 16,269 88.7588 1,444,017
2021-08-13 KOD BAKER BROS. ADVISORS LP 400 88.8150 400 88.8150 35,526
2021-08-12 KOD BAKER BROS. ADVISORS LP 300 85.5800 300 85.5800 25,674
2021-08-12 KOD BAKER BROS. ADVISORS LP 4,600 86.4447 4,600 86.4447 397,646
2021-08-12 KOD BAKER BROS. ADVISORS LP 6,086 88.0109 6,086 88.0109 535,634
2021-08-11 KOD BAKER BROS. ADVISORS LP 3,723 84.3903 3,723 84.3903 314,185
2021-08-11 KOD BAKER BROS. ADVISORS LP 600 85.7229 600 85.7229 51,434
2021-08-11 KOD BAKER BROS. ADVISORS LP 44,700 86.0734 44,700 86.0734 3,847,481
2021-08-11 KOD BAKER BROS. ADVISORS LP 4,500 87.9978 4,500 87.9978 395,990
2021-06-30 KOD BAKER BROS. ADVISORS LP 4,603 89.7392 4,603 89.7392 413,070
2021-06-30 KOD BAKER BROS. ADVISORS LP 22,353 90.2041 22,353 90.2041 2,016,332
2021-06-30 KOD BAKER BROS. ADVISORS LP 7,009 91.6359 7,009 91.6359 642,276
2021-06-30 KOD BAKER BROS. ADVISORS LP 121,612 92.7459 121,612 92.7459 11,279,014
2021-06-29 KOD BAKER BROS. ADVISORS LP 7,079 89.8709 7,079 89.8709 636,196
2021-06-29 KOD BAKER BROS. ADVISORS LP 3,847 89.8956 3,847 89.8956 345,828
2021-06-29 KOD BAKER BROS. ADVISORS LP 11,731 90.3911 11,731 90.3911 1,060,378
2021-06-29 KOD BAKER BROS. ADVISORS LP 1,200 90.3950 1,200 90.3950 108,474
2021-06-29 KOD BAKER BROS. ADVISORS LP 30,221 90.7037 30,221 90.7037 2,741,157
2021-06-28 KOD BAKER BROS. ADVISORS LP 5,200 90.2731 5,200 90.2731 469,420
2021-06-28 KOD BAKER BROS. ADVISORS LP 10,170 90.7617 10,170 90.7617 923,046
2021-06-28 KOD BAKER BROS. ADVISORS LP 22,445 91.7974 22,445 91.7974 2,060,393
2021-06-28 KOD BAKER BROS. ADVISORS LP 10,459 91.8678 10,459 91.8678 960,845
2020-11-20 KOD BAKER BROS. ADVISORS LP 116,158 108.0000 116,158 108.0000 12,545,064
2020-11-20 KOD BAKER BROS. ADVISORS LP 1,411,619 108.0000 1,411,619 108.0000 152,454,852
2020-09-25 KOD BAKER BROS. ADVISORS LP 933 55.3529 933 55.3529 51,644
2020-09-25 KOD BAKER BROS. ADVISORS LP 13,153 55.3529 13,153 55.3529 728,057
2020-09-25 KOD BAKER BROS. ADVISORS LP 334 56.7599 334 56.7599 18,958
2020-09-25 KOD BAKER BROS. ADVISORS LP 4,705 56.7599 4,705 56.7599 267,055
2020-09-25 KOD BAKER BROS. ADVISORS LP 1,365 56.9199 1,365 56.9199 77,696
2020-09-25 KOD BAKER BROS. ADVISORS LP 19,235 56.9199 19,235 56.9199 1,094,854
2020-09-25 KOD BAKER BROS. ADVISORS LP 557 58.0855 557 58.0855 32,354
2020-09-25 KOD BAKER BROS. ADVISORS LP 7,843 58.0855 7,843 58.0855 455,565
2020-09-24 KOD BAKER BROS. ADVISORS LP 306 51.4092 306 51.4092 15,731
2020-09-24 KOD BAKER BROS. ADVISORS LP 4,306 51.4092 4,306 51.4092 221,368
2020-09-24 KOD BAKER BROS. ADVISORS LP 2,081 52.1149 2,081 52.1149 108,451
2020-09-24 KOD BAKER BROS. ADVISORS LP 29,327 52.1149 29,327 52.1149 1,528,374
2020-09-23 KOD BAKER BROS. ADVISORS LP 80 51.9700 80 51.9700 4,158
2020-09-23 KOD BAKER BROS. ADVISORS LP 1,120 51.9700 1,120 51.9700 58,206
2020-09-23 KOD BAKER BROS. ADVISORS LP 743 52.3997 743 52.3997 38,933
2020-09-23 KOD BAKER BROS. ADVISORS LP 10,467 52.3997 10,467 52.3997 548,468
2020-09-23 KOD BAKER BROS. ADVISORS LP 5,278 52.4359 5,278 52.4359 276,757
2020-09-23 KOD BAKER BROS. ADVISORS LP 74,381 52.4359 74,381 52.4359 3,900,235
2020-09-22 KOD BAKER BROS. ADVISORS LP 779 49.7225 779 49.7225 38,734
2020-09-22 KOD BAKER BROS. ADVISORS LP 10,983 49.7225 10,983 49.7225 546,102
2020-09-22 KOD BAKER BROS. ADVISORS LP 2,601 50.1517 2,601 50.1517 130,445
2020-09-22 KOD BAKER BROS. ADVISORS LP 36,647 50.1517 36,647 50.1517 1,837,909
2020-09-22 KOD BAKER BROS. ADVISORS LP 1,587 51.9760 1,587 51.9760 82,486
2020-09-22 KOD BAKER BROS. ADVISORS LP 22,361 51.9760 22,361 51.9760 1,162,235
2020-09-08 KOD BAKER BROS. ADVISORS LP 15 45.8750 15 45.8750 688
2020-09-08 KOD BAKER BROS. ADVISORS LP 185 45.8750 185 45.8750 8,487
2020-09-08 KOD BAKER BROS. ADVISORS LP 1,272 47.0350 1,272 47.0350 59,829
2020-09-08 KOD BAKER BROS. ADVISORS LP 15,807 47.0350 15,807 47.0350 743,482
2020-09-08 KOD BAKER BROS. ADVISORS LP 6,151 47.3874 6,151 47.3874 291,480
2020-09-08 KOD BAKER BROS. ADVISORS LP 76,473 47.3874 76,473 47.3874 3,623,857
2020-09-08 KOD BAKER BROS. ADVISORS LP 1,220 47.4690 1,220 47.4690 57,912
2020-09-08 KOD BAKER BROS. ADVISORS LP 15,172 47.4690 15,172 47.4690 720,200
2020-09-04 KOD BAKER BROS. ADVISORS LP 950 45.2963 950 45.2963 43,031
2020-09-04 KOD BAKER BROS. ADVISORS LP 12,132 45.2963 12,132 45.2963 549,535
2020-09-04 KOD BAKER BROS. ADVISORS LP 2,295 46.6171 2,295 46.6171 106,986
2020-09-04 KOD BAKER BROS. ADVISORS LP 29,319 46.6171 29,319 46.6171 1,366,767
2020-09-04 KOD BAKER BROS. ADVISORS LP 2,054 47.2591 2,054 47.2591 97,070
2020-09-04 KOD BAKER BROS. ADVISORS LP 26,238 47.2591 26,238 47.2591 1,239,984
2020-09-04 KOD BAKER BROS. ADVISORS LP 712 47.4982 712 47.4982 33,819
2020-09-04 KOD BAKER BROS. ADVISORS LP 9,101 47.4982 9,101 47.4982 432,281
2020-09-03 KOD BAKER BROS. ADVISORS LP 185 46.9681 185 46.9681 8,689
2020-09-03 KOD BAKER BROS. ADVISORS LP 2,359 46.9681 2,359 46.9681 110,798
2020-09-03 KOD BAKER BROS. ADVISORS LP 234 47.4472 234 47.4472 11,103
2020-09-03 KOD BAKER BROS. ADVISORS LP 2,987 47.4472 2,987 47.4472 141,725
2020-09-03 KOD BAKER BROS. ADVISORS LP 6,062 47.5968 6,062 47.5968 288,532
2020-09-03 KOD BAKER BROS. ADVISORS LP 77,456 47.5968 77,456 47.5968 3,686,658
2020-09-03 KOD BAKER BROS. ADVISORS LP 2,512 49.0000 2,512 49.0000 123,088
2020-09-03 KOD BAKER BROS. ADVISORS LP 32,088 49.0000 32,088 49.0000 1,572,312
2020-08-21 KOD BAKER BROS. ADVISORS LP 3,386 47.7421 3,386 47.7421 161,655
2020-08-21 KOD BAKER BROS. ADVISORS LP 42,714 47.7421 42,714 47.7421 2,039,256
2020-08-21 KOD BAKER BROS. ADVISORS LP 181 48.7447 181 48.7447 8,823
2020-08-21 KOD BAKER BROS. ADVISORS LP 2,286 48.7447 2,286 48.7447 111,430
2020-08-21 KOD BAKER BROS. ADVISORS LP 6,645 49.0831 6,645 49.0831 326,157
2020-08-21 KOD BAKER BROS. ADVISORS LP 83,832 49.0831 83,832 49.0831 4,114,734
2020-08-20 KOD BAKER BROS. ADVISORS LP 283 46.3018 283 46.3018 13,103
2020-08-20 KOD BAKER BROS. ADVISORS LP 3,576 46.3018 3,576 46.3018 165,575
2020-08-20 KOD BAKER BROS. ADVISORS LP 843 46.4959 843 46.4959 39,196
2020-08-20 KOD BAKER BROS. ADVISORS LP 10,640 46.4959 10,640 46.4959 494,716
2020-08-20 KOD BAKER BROS. ADVISORS LP 3,262 47.7213 3,262 47.7213 155,667
2020-08-20 KOD BAKER BROS. ADVISORS LP 41,155 47.7213 41,155 47.7213 1,963,970
2020-08-20 KOD BAKER BROS. ADVISORS LP 60 47.8226 60 47.8226 2,869
2020-08-20 KOD BAKER BROS. ADVISORS LP 754 47.8226 754 47.8226 36,058
2020-08-19 KOD BAKER BROS. ADVISORS LP 284 46.9865 284 46.9865 13,344
2020-08-19 KOD BAKER BROS. ADVISORS LP 3,585 46.9865 3,585 46.9865 168,447
2020-03-18 KOD BAKER BROS. ADVISORS LP 1,542 36.6933 1,542 36.6933 56,581
2020-03-18 KOD BAKER BROS. ADVISORS LP 17,058 36.6933 17,058 36.6933 625,914
2020-03-18 KOD BAKER BROS. ADVISORS LP 563 37.7478 563 37.7478 21,252
2020-03-18 KOD BAKER BROS. ADVISORS LP 6,237 37.7478 6,237 37.7478 235,433
2020-03-18 KOD BAKER BROS. ADVISORS LP 828 38.3797 828 38.3797 31,778
2020-03-18 KOD BAKER BROS. ADVISORS LP 9,172 38.3797 9,172 38.3797 352,019
2020-03-17 KOD BAKER BROS. ADVISORS LP 828 38.9850 828 38.9850 32,280
2020-03-17 KOD BAKER BROS. ADVISORS LP 9,172 38.9850 9,172 38.9850 357,570
2020-03-16 KOD BAKER BROS. ADVISORS LP 8,666 39.9711 8,666 39.9711 346,390
2020-03-16 KOD BAKER BROS. ADVISORS LP 95,934 39.9711 95,934 39.9711 3,834,588
2020-02-26 KOD BAKER BROS. ADVISORS LP 811 59.6089 811 59.6089 48,343
2020-02-26 KOD BAKER BROS. ADVISORS LP 8,989 59.6089 8,989 59.6089 535,824
2020-02-26 KOD BAKER BROS. ADVISORS LP 7,460 57.8190 7,460 57.8190 431,330
2020-02-26 KOD BAKER BROS. ADVISORS LP 82,740 57.8190 82,740 57.8190 4,783,944
2020-02-25 KOD BAKER BROS. ADVISORS LP 1,298 58.7987 1,298 58.7987 76,321
2020-02-25 KOD BAKER BROS. ADVISORS LP 14,402 58.7987 14,402 58.7987 846,819
2020-02-25 KOD BAKER BROS. ADVISORS LP 1,267 57.2187 1,267 57.2187 72,496
2020-02-25 KOD BAKER BROS. ADVISORS LP 14,051 57.2187 14,051 57.2187 803,980
2020-02-25 KOD BAKER BROS. ADVISORS LP 13,164 57.6840 13,164 57.6840 759,352
2020-02-25 KOD BAKER BROS. ADVISORS LP 145,994 57.6840 145,994 57.6840 8,421,518
2020-02-25 KOD BAKER BROS. ADVISORS LP 1,319 59.9851 1,319 59.9851 79,120
2020-02-25 KOD BAKER BROS. ADVISORS LP 14,631 59.9851 14,631 59.9851 877,642
2020-02-24 KOD BAKER BROS. ADVISORS LP 164 55.7734 164 55.7734 9,147
2020-02-24 KOD BAKER BROS. ADVISORS LP 1,813 55.7734 1,813 55.7734 101,117
2020-02-24 KOD BAKER BROS. ADVISORS LP 8 55.4525 8 55.4525 444
2020-02-24 KOD BAKER BROS. ADVISORS LP 92 55.4525 92 55.4525 5,102
2020-02-24 KOD BAKER BROS. ADVISORS LP 912 56.2471 912 56.2471 51,297
2020-02-24 KOD BAKER BROS. ADVISORS LP 10,121 56.2471 10,121 56.2471 569,277
2020-02-24 KOD BAKER BROS. ADVISORS LP 523 56.6215 523 56.6215 29,613
2020-02-24 KOD BAKER BROS. ADVISORS LP 5,804 56.6215 5,804 56.6215 328,631
2020-02-24 KOD BAKER BROS. ADVISORS LP 1,921 56.6881 1,921 56.6881 108,898
2020-02-24 KOD BAKER BROS. ADVISORS LP 21,301 56.6881 21,301 56.6881 1,207,513
2020-02-24 KOD BAKER BROS. ADVISORS LP 323 57.6204 323 57.6204 18,611
2020-02-24 KOD BAKER BROS. ADVISORS LP 3,577 57.6204 3,577 57.6204 206,108
2020-02-24 KOD BAKER BROS. ADVISORS LP 642 58.3861 642 58.3861 37,484
2020-02-24 KOD BAKER BROS. ADVISORS LP 7,122 58.3861 7,122 58.3861 415,826
2020-02-24 KOD BAKER BROS. ADVISORS LP 612 58.5434 612 58.5434 35,829
2020-02-24 KOD BAKER BROS. ADVISORS LP 6,788 58.5434 6,788 58.5434 397,393
2020-02-24 KOD BAKER BROS. ADVISORS LP 777 60.7727 777 60.7727 47,220
2020-02-24 KOD BAKER BROS. ADVISORS LP 8,623 60.7727 8,623 60.7727 524,043
2019-12-06 KOD BAKER BROS. ADVISORS LP 158,180 46.0000 158,180 46.0000 7,276,280
2019-12-06 KOD BAKER BROS. ADVISORS LP 1,743,993 46.0000 1,743,993 46.0000 80,223,678
2018-10-09 KOD BAKER BROS. ADVISORS LP 251,898 10.0000 251,898 10.0000 2,518,980
2018-10-09 KOD BAKER BROS. ADVISORS LP 2,248,102 10.0000 2,248,102 10.0000 22,481,020

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KOD / Kodiak Sciences Inc. Insider Trades
KOD / Kodiak Sciences Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KOD / Kodiak Sciences Inc. Insider Trades
KYMR / Kymera Therapeutics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2025-12-11 KYMR BAKER BROS. ADVISORS LP 167,192 86.0000 167,192 86.0000 14,378,512 77 95.0300 1,509,744 10.50
2025-12-11 KYMR BAKER BROS. ADVISORS LP 1,838,621 86.0000 1,838,621 86.0000 158,121,406
2025-06-30 KYMR BAKER BROS. ADVISORS LP 55,191 44.0000 55,191 44.0000 2,428,404
2025-06-30 KYMR BAKER BROS. ADVISORS LP 600,309 44.0000 600,309 44.0000 26,413,596
2024-08-20 KYMR BAKER BROS. ADVISORS LP 1 46.4100 1 46.4100 46

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KYMR / Kymera Therapeutics, Inc. Insider Trades
KYMR / Kymera Therapeutics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

KYMR / Kymera Therapeutics, Inc. Insider Trades
MDGL / Madrigal Pharmaceuticals, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2025-08-20 MDGL BAKER BROS. ADVISORS LP 480 380.4365 480 380.4365 182,610 124 602.8300 106,749 58.46
2025-08-20 MDGL BAKER BROS. ADVISORS LP 5,209 380.4365 5,209 380.4365 1,981,694
2025-08-20 MDGL BAKER BROS. ADVISORS LP 176 380.7800 176 380.7800 67,017
2025-08-20 MDGL BAKER BROS. ADVISORS LP 1,919 380.7800 1,919 380.7800 730,717
2025-08-20 MDGL BAKER BROS. ADVISORS LP 873 381.1216 873 381.1216 332,719
2025-08-20 MDGL BAKER BROS. ADVISORS LP 9,477 381.1216 9,477 381.1216 3,611,889
2025-08-20 MDGL BAKER BROS. ADVISORS LP 105 382.2891 105 382.2891 40,140
2025-08-20 MDGL BAKER BROS. ADVISORS LP 1,136 382.2891 1,136 382.2891 434,280
2025-08-20 MDGL BAKER BROS. ADVISORS LP 262 382.8213 262 382.8213 100,299
2025-08-20 MDGL BAKER BROS. ADVISORS LP 2,838 382.8213 2,838 382.8213 1,086,447
2025-08-20 MDGL BAKER BROS. ADVISORS LP 373 383.7872 373 383.7872 143,153
2025-08-20 MDGL BAKER BROS. ADVISORS LP 4,049 383.7872 4,049 383.7872 1,553,954
2025-08-20 MDGL BAKER BROS. ADVISORS LP 1,248 385.0573 1,248 385.0573 480,552
2025-08-20 MDGL BAKER BROS. ADVISORS LP 13,545 385.0573 13,545 385.0573 5,215,601
2025-08-20 MDGL BAKER BROS. ADVISORS LP 409 387.0680 409 387.0680 158,311
2025-08-20 MDGL BAKER BROS. ADVISORS LP 4,441 387.0680 4,441 387.0680 1,718,969
2025-08-20 MDGL BAKER BROS. ADVISORS LP 34 389.0000 34 389.0000 13,226
2025-08-20 MDGL BAKER BROS. ADVISORS LP 366 389.0000 366 389.0000 142,374
2025-08-20 MDGL BAKER BROS. ADVISORS LP 231 389.8878 231 389.8878 90,064
2025-08-20 MDGL BAKER BROS. ADVISORS LP 2,506 389.8878 2,506 389.8878 977,059
2025-08-20 MDGL BAKER BROS. ADVISORS LP 862 392.2429 862 392.2429 338,113
2025-08-20 MDGL BAKER BROS. ADVISORS LP 9,362 392.2429 9,362 392.2429 3,672,178
2025-08-18 MDGL BAKER BROS. ADVISORS LP 177 353.8755 177 353.8755 62,636
2025-08-18 MDGL BAKER BROS. ADVISORS LP 1,923 353.8755 1,923 353.8755 680,503
2025-08-18 MDGL BAKER BROS. ADVISORS LP 84 355.0000 84 355.0000 29,820
2025-08-18 MDGL BAKER BROS. ADVISORS LP 916 355.0000 916 355.0000 325,180
2025-08-18 MDGL BAKER BROS. ADVISORS LP 767 357.0232 767 357.0232 273,837
2025-08-18 MDGL BAKER BROS. ADVISORS LP 8,328 357.0232 8,328 357.0232 2,973,289
2025-08-18 MDGL BAKER BROS. ADVISORS LP 228 358.2100 228 358.2100 81,672
2025-08-18 MDGL BAKER BROS. ADVISORS LP 2,472 358.2100 2,472 358.2100 885,495
2025-08-18 MDGL BAKER BROS. ADVISORS LP 784 359.3931 784 359.3931 281,764
2025-08-18 MDGL BAKER BROS. ADVISORS LP 8,514 359.3931 8,514 359.3931 3,059,873
2025-08-18 MDGL BAKER BROS. ADVISORS LP 502 361.3736 502 361.3736 181,410
2025-08-18 MDGL BAKER BROS. ADVISORS LP 5,443 361.3736 5,443 361.3736 1,966,957
2025-08-18 MDGL BAKER BROS. ADVISORS LP 515 362.3881 515 362.3881 186,630
2025-08-18 MDGL BAKER BROS. ADVISORS LP 5,587 362.3881 5,587 362.3881 2,024,662
2025-08-18 MDGL BAKER BROS. ADVISORS LP 255 363.7474 255 363.7474 92,756
2025-08-18 MDGL BAKER BROS. ADVISORS LP 2,772 363.7474 2,772 363.7474 1,008,308
2025-08-18 MDGL BAKER BROS. ADVISORS LP 211 366.2992 211 366.2992 77,289
2025-08-18 MDGL BAKER BROS. ADVISORS LP 2,289 366.2992 2,289 366.2992 838,459
2025-08-18 MDGL BAKER BROS. ADVISORS LP 442 367.7710 442 367.7710 162,555
2025-08-18 MDGL BAKER BROS. ADVISORS LP 4,798 367.7710 4,798 367.7710 1,764,565
2025-08-18 MDGL BAKER BROS. ADVISORS LP 131 368.8400 131 368.8400 48,318
2025-08-18 MDGL BAKER BROS. ADVISORS LP 1,419 368.8400 1,419 368.8400 523,384
2025-08-18 MDGL BAKER BROS. ADVISORS LP 253 369.3350 253 369.3350 93,442
2025-08-18 MDGL BAKER BROS. ADVISORS LP 2,747 369.3350 2,747 369.3350 1,014,563
2025-08-18 MDGL BAKER BROS. ADVISORS LP 506 371.0050 506 371.0050 187,729
2025-08-18 MDGL BAKER BROS. ADVISORS LP 5,494 371.0050 5,494 371.0050 2,038,301
2025-08-18 MDGL BAKER BROS. ADVISORS LP 933 372.1573 933 372.1573 347,223
2025-08-18 MDGL BAKER BROS. ADVISORS LP 10,128 372.1573 10,128 372.1573 3,769,209
2025-08-18 MDGL BAKER BROS. ADVISORS LP 2,460 372.8693 2,460 372.8693 917,258
2025-08-18 MDGL BAKER BROS. ADVISORS LP 26,704 372.8693 26,704 372.8693 9,957,102
2025-08-18 MDGL BAKER BROS. ADVISORS LP 675 374.4338 675 374.4338 252,743
2025-08-18 MDGL BAKER BROS. ADVISORS LP 7,325 374.4338 7,325 374.4338 2,742,728
2023-12-14 MDGL BAKER BROS. ADVISORS LP 107 226.9710 107 226.9710 24,286
2023-12-14 MDGL BAKER BROS. ADVISORS LP 1,343 226.9710 1,343 226.9710 304,822
2023-12-14 MDGL BAKER BROS. ADVISORS LP 925 227.8570 925 227.8570 210,768
2023-12-14 MDGL BAKER BROS. ADVISORS LP 11,602 227.8570 11,602 227.8570 2,643,597
2023-12-14 MDGL BAKER BROS. ADVISORS LP 176 228.7893 176 228.7893 40,267
2023-12-14 MDGL BAKER BROS. ADVISORS LP 2,204 228.7893 2,204 228.7893 504,252
2023-12-14 MDGL BAKER BROS. ADVISORS LP 316 229.8647 316 229.8647 72,637
2023-12-14 MDGL BAKER BROS. ADVISORS LP 3,960 229.8647 3,960 229.8647 910,264
2023-12-13 MDGL BAKER BROS. ADVISORS LP 818 216.6994 818 216.6994 177,260
2023-12-13 MDGL BAKER BROS. ADVISORS LP 10,264 216.6994 10,264 216.6994 2,224,203
2023-12-13 MDGL BAKER BROS. ADVISORS LP 869 217.5152 869 217.5152 189,021
2023-12-13 MDGL BAKER BROS. ADVISORS LP 10,894 217.5152 10,894 217.5152 2,369,611
2023-12-13 MDGL BAKER BROS. ADVISORS LP 2,373 218.4583 2,373 218.4583 518,402
2023-12-13 MDGL BAKER BROS. ADVISORS LP 29,738 218.4583 29,738 218.4583 6,496,513
2023-12-13 MDGL BAKER BROS. ADVISORS LP 360 219.8652 360 219.8652 79,151
2023-12-13 MDGL BAKER BROS. ADVISORS LP 4,518 219.8652 4,518 219.8652 993,351
2023-12-13 MDGL BAKER BROS. ADVISORS LP 361 221.7787 361 221.7787 80,062
2023-12-13 MDGL BAKER BROS. ADVISORS LP 4,532 221.7787 4,532 221.7787 1,005,101
2023-12-13 MDGL BAKER BROS. ADVISORS LP 738 222.6760 738 222.6760 164,335
2023-12-13 MDGL BAKER BROS. ADVISORS LP 9,262 222.6760 9,262 222.6760 2,062,425
2023-12-13 MDGL BAKER BROS. ADVISORS LP 29 223.9374 29 223.9374 6,494
2023-12-13 MDGL BAKER BROS. ADVISORS LP 363 223.9374 363 223.9374 81,289
2023-12-13 MDGL BAKER BROS. ADVISORS LP 446 224.9117 446 224.9117 100,311
2023-12-13 MDGL BAKER BROS. ADVISORS LP 5,594 224.9117 5,594 224.9117 1,258,156
2023-12-12 MDGL BAKER BROS. ADVISORS LP 7 205.3200 7 205.3200 1,437
2023-12-12 MDGL BAKER BROS. ADVISORS LP 93 205.3200 93 205.3200 19,095
2023-12-12 MDGL BAKER BROS. ADVISORS LP 56 205.6000 56 205.6000 11,514
2023-12-12 MDGL BAKER BROS. ADVISORS LP 708 205.6000 708 205.6000 145,565
2023-12-12 MDGL BAKER BROS. ADVISORS LP 52 206.9321 52 206.9321 10,760
2023-12-12 MDGL BAKER BROS. ADVISORS LP 648 206.9321 648 206.9321 134,092
2023-12-12 MDGL BAKER BROS. ADVISORS LP 30 208.6913 30 208.6913 6,261
2023-12-12 MDGL BAKER BROS. ADVISORS LP 370 208.6913 370 208.6913 77,216
2023-12-12 MDGL BAKER BROS. ADVISORS LP 7 209.7650 7 209.7650 1,468
2023-12-12 MDGL BAKER BROS. ADVISORS LP 93 209.7650 93 209.7650 19,508
2023-12-12 MDGL BAKER BROS. ADVISORS LP 52 212.0414 52 212.0414 11,026
2023-12-12 MDGL BAKER BROS. ADVISORS LP 648 212.0414 648 212.0414 137,403
2023-12-12 MDGL BAKER BROS. ADVISORS LP 15 213.6250 15 213.6250 3,204
2023-12-12 MDGL BAKER BROS. ADVISORS LP 185 213.6250 185 213.6250 39,521
2023-12-12 MDGL BAKER BROS. ADVISORS LP 41 213.7994 41 213.7994 8,766
2023-12-12 MDGL BAKER BROS. ADVISORS LP 515 213.7994 515 213.7994 110,107
2023-12-12 MDGL BAKER BROS. ADVISORS LP 53 214.7223 53 214.7223 11,380
2023-12-12 MDGL BAKER BROS. ADVISORS LP 668 214.7223 668 214.7223 143,434
2023-12-12 MDGL BAKER BROS. ADVISORS LP 141 216.6683 141 216.6683 30,550
2023-12-12 MDGL BAKER BROS. ADVISORS LP 1,769 216.6683 1,769 216.6683 383,286
2023-12-12 MDGL BAKER BROS. ADVISORS LP 15 217.9000 15 217.9000 3,268
2023-12-12 MDGL BAKER BROS. ADVISORS LP 185 217.9000 185 217.9000 40,312
2023-12-12 MDGL BAKER BROS. ADVISORS LP 229 217.9078 229 217.9078 49,901
2023-12-12 MDGL BAKER BROS. ADVISORS LP 2,873 217.9078 2,873 217.9078 626,049
2023-12-12 MDGL BAKER BROS. ADVISORS LP 1,195 219.2410 1,195 219.2410 261,993
2023-12-12 MDGL BAKER BROS. ADVISORS LP 15,005 219.2410 15,005 219.2410 3,289,711
2023-12-12 MDGL BAKER BROS. ADVISORS LP 352 220.6546 352 220.6546 77,670
2023-12-12 MDGL BAKER BROS. ADVISORS LP 4,408 220.6546 4,408 220.6546 972,645
2023-12-12 MDGL BAKER BROS. ADVISORS LP 308 221.2418 308 221.2418 68,142
2023-12-12 MDGL BAKER BROS. ADVISORS LP 3,857 221.2418 3,857 221.2418 853,330
2023-11-21 MDGL BAKER BROS. ADVISORS LP 12 185.9442 12 185.9442 2,231
2023-11-21 MDGL BAKER BROS. ADVISORS LP 146 185.9442 146 185.9442 27,148
2023-11-21 MDGL BAKER BROS. ADVISORS LP 31 183.1600 31 183.1600 5,678
2023-11-21 MDGL BAKER BROS. ADVISORS LP 369 183.1600 369 183.1600 67,586
2023-11-21 MDGL BAKER BROS. ADVISORS LP 53 186.3171 53 186.3171 9,875
2023-11-21 MDGL BAKER BROS. ADVISORS LP 647 186.3171 647 186.3171 120,547
2023-11-21 MDGL BAKER BROS. ADVISORS LP 115 186.5930 115 186.5930 21,458
2023-11-21 MDGL BAKER BROS. ADVISORS LP 1,385 186.5930 1,385 186.5930 258,431
2023-11-21 MDGL BAKER BROS. ADVISORS LP 176 187.2439 176 187.2439 32,955
2023-11-21 MDGL BAKER BROS. ADVISORS LP 2,124 187.2439 2,124 187.2439 397,706
2023-11-21 MDGL BAKER BROS. ADVISORS LP 388 187.2707 388 187.2707 72,661
2023-11-21 MDGL BAKER BROS. ADVISORS LP 4,712 187.2707 4,712 187.2707 882,420
2023-11-21 MDGL BAKER BROS. ADVISORS LP 1,076 188.3232 1,076 188.3232 202,636
2023-11-21 MDGL BAKER BROS. ADVISORS LP 13,011 188.3232 13,011 188.3232 2,450,273
2023-11-21 MDGL BAKER BROS. ADVISORS LP 1,117 188.4649 1,117 188.4649 210,515
2023-11-21 MDGL BAKER BROS. ADVISORS LP 13,505 188.4649 13,505 188.4649 2,545,218
2023-11-21 MDGL BAKER BROS. ADVISORS LP 1,291 188.7029 1,291 188.7029 243,615
2023-11-21 MDGL BAKER BROS. ADVISORS LP 15,620 188.7029 15,620 188.7029 2,947,539
2023-11-21 MDGL BAKER BROS. ADVISORS LP 655 190.1361 655 190.1361 124,539
2023-11-21 MDGL BAKER BROS. ADVISORS LP 7,917 190.1361 7,917 190.1361 1,505,308
2023-11-20 MDGL BAKER BROS. ADVISORS LP 153 181.9300 153 181.9300 27,835
2023-11-20 MDGL BAKER BROS. ADVISORS LP 1,847 181.9300 1,847 181.9300 336,025
2023-11-20 MDGL BAKER BROS. ADVISORS LP 579 183.3999 579 183.3999 106,189
2023-11-20 MDGL BAKER BROS. ADVISORS LP 7,010 183.3999 7,010 183.3999 1,285,633
2023-11-20 MDGL BAKER BROS. ADVISORS LP 100 185.8650 100 185.8650 18,586
2023-11-20 MDGL BAKER BROS. ADVISORS LP 1,206 185.8650 1,206 185.8650 224,153
2023-11-20 MDGL BAKER BROS. ADVISORS LP 405 187.3450 405 187.3450 75,875
2023-11-20 MDGL BAKER BROS. ADVISORS LP 4,895 187.3450 4,895 187.3450 917,054
2023-11-20 MDGL BAKER BROS. ADVISORS LP 95 188.8359 95 188.8359 17,939
2023-11-20 MDGL BAKER BROS. ADVISORS LP 1,147 188.8359 1,147 188.8359 216,595
2023-11-20 MDGL BAKER BROS. ADVISORS LP 250 189.6978 250 189.6978 47,424
2023-11-20 MDGL BAKER BROS. ADVISORS LP 3,022 189.6978 3,022 189.6978 573,267
2023-11-17 MDGL BAKER BROS. ADVISORS LP 54 167.6300 54 167.6300 9,052
2023-11-17 MDGL BAKER BROS. ADVISORS LP 646 167.6300 646 167.6300 108,289
2023-11-17 MDGL BAKER BROS. ADVISORS LP 93 168.7825 93 168.7825 15,697
2023-11-17 MDGL BAKER BROS. ADVISORS LP 1,107 168.7825 1,107 168.7825 186,842
2023-11-17 MDGL BAKER BROS. ADVISORS LP 39 171.7900 39 171.7900 6,700
2023-11-17 MDGL BAKER BROS. ADVISORS LP 461 171.7900 461 171.7900 79,195
2023-11-17 MDGL BAKER BROS. ADVISORS LP 350 173.2016 350 173.2016 60,621
2023-11-17 MDGL BAKER BROS. ADVISORS LP 4,151 173.2016 4,151 173.2016 718,960
2023-11-17 MDGL BAKER BROS. ADVISORS LP 140 173.7481 140 173.7481 24,325
2023-11-17 MDGL BAKER BROS. ADVISORS LP 1,660 173.7481 1,660 173.7481 288,422
2023-11-17 MDGL BAKER BROS. ADVISORS LP 82 174.6698 82 174.6698 14,323
2023-11-17 MDGL BAKER BROS. ADVISORS LP 978 174.6698 978 174.6698 170,827
2023-11-17 MDGL BAKER BROS. ADVISORS LP 1,528 174.8748 1,528 174.8748 267,209
2023-11-17 MDGL BAKER BROS. ADVISORS LP 18,125 174.8748 18,125 174.8748 3,169,606
2023-11-17 MDGL BAKER BROS. ADVISORS LP 415 175.7185 415 175.7185 72,923
2023-11-17 MDGL BAKER BROS. ADVISORS LP 4,923 175.7185 4,923 175.7185 865,062
2023-11-17 MDGL BAKER BROS. ADVISORS LP 903 175.8179 903 175.8179 158,764
2023-11-17 MDGL BAKER BROS. ADVISORS LP 10,715 175.8179 10,715 175.8179 1,883,889
2023-11-15 MDGL BAKER BROS. ADVISORS LP 1,181 161.9660 1,181 161.9660 191,282
2023-11-15 MDGL BAKER BROS. ADVISORS LP 14,018 161.9660 14,018 161.9660 2,270,439
2023-11-14 MDGL BAKER BROS. ADVISORS LP 299 154.5969 299 154.5969 46,224
2023-11-14 MDGL BAKER BROS. ADVISORS LP 3,542 154.5969 3,542 154.5969 547,582
2023-11-14 MDGL BAKER BROS. ADVISORS LP 507 152.4800 507 152.4800 77,307
2023-11-14 MDGL BAKER BROS. ADVISORS LP 6,022 152.4800 6,022 152.4800 918,235
2023-11-14 MDGL BAKER BROS. ADVISORS LP 54 152.2129 54 152.2129 8,219
2023-11-14 MDGL BAKER BROS. ADVISORS LP 646 152.2129 646 152.2129 98,330
2023-11-14 MDGL BAKER BROS. ADVISORS LP 242 153.2523 242 153.2523 37,087
2023-11-14 MDGL BAKER BROS. ADVISORS LP 2,877 153.2523 2,877 153.2523 440,907
2023-11-14 MDGL BAKER BROS. ADVISORS LP 683 153.9736 683 153.9736 105,164
2023-11-14 MDGL BAKER BROS. ADVISORS LP 8,098 153.9736 8,098 153.9736 1,246,878
2023-11-14 MDGL BAKER BROS. ADVISORS LP 1,142 154.7801 1,142 154.7801 176,759
2023-11-14 MDGL BAKER BROS. ADVISORS LP 13,548 154.7801 13,548 154.7801 2,096,961
2023-11-14 MDGL BAKER BROS. ADVISORS LP 2,658 156.4244 2,658 156.4244 415,776
2023-11-14 MDGL BAKER BROS. ADVISORS LP 31,530 156.4244 31,530 156.4244 4,932,061
2023-11-13 MDGL BAKER BROS. ADVISORS LP 265 136.1805 265 136.1805 36,088
2023-11-13 MDGL BAKER BROS. ADVISORS LP 3,144 136.1805 3,144 136.1805 428,151
2023-11-13 MDGL BAKER BROS. ADVISORS LP 311 136.9089 311 136.9089 42,579
2023-11-13 MDGL BAKER BROS. ADVISORS LP 3,693 136.9089 3,693 136.9089 505,605
2023-11-13 MDGL BAKER BROS. ADVISORS LP 390 137.6855 390 137.6855 53,697
2023-11-13 MDGL BAKER BROS. ADVISORS LP 4,631 137.6855 4,631 137.6855 637,622
2023-11-13 MDGL BAKER BROS. ADVISORS LP 427 140.9024 427 140.9024 60,165
2023-11-13 MDGL BAKER BROS. ADVISORS LP 5,072 140.9024 5,072 140.9024 714,657
2023-11-13 MDGL BAKER BROS. ADVISORS LP 910 141.4450 910 141.4450 128,715
2023-11-13 MDGL BAKER BROS. ADVISORS LP 10,790 141.4450 10,790 141.4450 1,526,192
2023-11-13 MDGL BAKER BROS. ADVISORS LP 109 142.8575 109 142.8575 15,571
2023-11-13 MDGL BAKER BROS. ADVISORS LP 1,291 142.8575 1,291 142.8575 184,429
2023-11-13 MDGL BAKER BROS. ADVISORS LP 537 145.4592 537 145.4592 78,112
2023-11-13 MDGL BAKER BROS. ADVISORS LP 6,369 145.4592 6,369 145.4592 926,430
2023-11-13 MDGL BAKER BROS. ADVISORS LP 252 145.9775 252 145.9775 36,786
2023-11-13 MDGL BAKER BROS. ADVISORS LP 2,994 145.9775 2,994 145.9775 437,057
2023-11-13 MDGL BAKER BROS. ADVISORS LP 2,228 146.2104 2,228 146.2104 325,757
2023-11-13 MDGL BAKER BROS. ADVISORS LP 26,426 146.2104 26,426 146.2104 3,863,756

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

MDGL / Madrigal Pharmaceuticals, Inc. Insider Trades
MDGL / Madrigal Pharmaceuticals, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

MDGL / Madrigal Pharmaceuticals, Inc. Insider Trades
NTLA / Intellia Therapeutics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2016-05-11 NTLA BAKER BROS. ADVISORS LP 20,469 18.0000 20,469 18.0000 368,442 20 29.57 236,826 64.28
2016-05-11 NTLA BAKER BROS. ADVISORS LP 179,531 18.0000 179,531 18.0000 3,231,558

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

NTLA / Intellia Therapeutics, Inc. Insider Trades
NTLA / Intellia Therapeutics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

NTLA / Intellia Therapeutics, Inc. Insider Trades
PRLD / Prelude Therapeutics Incorporated內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2021-01-11 PRLD BAKER BROS. ADVISORS LP 12,444 60.0000 12,444 60.0000 746,640 30 91.68 394,226 52.80
2021-01-11 PRLD BAKER BROS. ADVISORS LP 154,222 60.0000 154,222 60.0000 9,253,320
2020-09-29 PRLD BAKER BROS. ADVISORS LP 104,628 19.0000 104,628 19.0000 1,987,932
2020-09-29 PRLD BAKER BROS. ADVISORS LP 1,474,319 19.0000 1,474,319 19.0000 28,012,061

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

PRLD / Prelude Therapeutics Incorporated Insider Trades
PRLD / Prelude Therapeutics Incorporated內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

PRLD / Prelude Therapeutics Incorporated Insider Trades
REPL / Replimune Group, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

REPL / Replimune Group, Inc. Insider Trades
REPL / Replimune Group, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

REPL / Replimune Group, Inc. Insider Trades
RYTM / Rhythm Pharmaceuticals, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2017-10-05 RYTM BAKER BROS. ADVISORS LP 87,809 17.0000 87,809 17.0000 1,492,753 273 35.85 1,655,200 110.88
2017-10-05 RYTM BAKER BROS. ADVISORS LP 797,191 17.0000 797,191 17.0000 13,552,247

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

RYTM / Rhythm Pharmaceuticals, Inc. Insider Trades
RYTM / Rhythm Pharmaceuticals, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

RYTM / Rhythm Pharmaceuticals, Inc. Insider Trades
SERA / Sera Prognostics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

SERA / Sera Prognostics, Inc. Insider Trades
SERA / Sera Prognostics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

SERA / Sera Prognostics, Inc. Insider Trades
SYRE / Spyre Therapeutics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

SYRE / Spyre Therapeutics, Inc. Insider Trades
SYRE / Spyre Therapeutics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

SYRE / Spyre Therapeutics, Inc. Insider Trades
TCRX / TScan Therapeutics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2022-05-11 TCRX BAKER BROS. ADVISORS LP 2,882 1.9853 2,882 1.9853 5,722 364 4.8500 8,257 144.32
2022-05-11 TCRX BAKER BROS. ADVISORS LP 22,983 1.9853 22,983 1.9853 45,628
2022-05-10 TCRX BAKER BROS. ADVISORS LP 40,800 1.7000 40,800 1.7000 69,360
2022-05-10 TCRX BAKER BROS. ADVISORS LP 325,373 1.7000 325,373 1.7000 553,134
2022-05-10 TCRX BAKER BROS. ADVISORS LP 12,769 1.9342 12,769 1.9342 24,698
2022-05-10 TCRX BAKER BROS. ADVISORS LP 101,831 1.9342 101,831 1.9342 196,962
2022-05-10 TCRX BAKER BROS. ADVISORS LP 95,060 1.9500 95,060 1.9500 185,367
2022-05-10 TCRX BAKER BROS. ADVISORS LP 758,094 1.9500 758,094 1.9500 1,478,283
2021-07-20 TCRX BAKER BROS. ADVISORS LP 104,698 15.0000 104,698 15.0000 1,570,470
2021-07-20 TCRX BAKER BROS. ADVISORS LP 1,320,302 15.0000 1,320,302 15.0000 19,804,530

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

TCRX / TScan Therapeutics, Inc. Insider Trades
TCRX / TScan Therapeutics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

TCRX / TScan Therapeutics, Inc. Insider Trades
TRDA / Entrada Therapeutics, Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2025-11-20 TRDA BAKER BROS. ADVISORS LP 1,213 9.0688 1,213 9.0688 11,000 167 16.0300 8,444 76.77
2025-11-20 TRDA BAKER BROS. ADVISORS LP 13,386 9.0688 13,386 9.0688 121,395
2025-11-20 TRDA BAKER BROS. ADVISORS LP 1,186 9.0728 1,186 9.0728 10,760
2025-11-20 TRDA BAKER BROS. ADVISORS LP 13,082 9.0728 13,082 9.0728 118,690
2025-11-12 TRDA BAKER BROS. ADVISORS LP 7,321 7.7315 7,321 7.7315 56,602
2025-11-12 TRDA BAKER BROS. ADVISORS LP 80,881 7.7315 80,881 7.7315 625,331
2025-11-12 TRDA BAKER BROS. ADVISORS LP 1,040 7.9547 1,040 7.9547 8,273
2025-11-12 TRDA BAKER BROS. ADVISORS LP 11,494 7.9547 11,494 7.9547 91,431
2025-11-11 TRDA BAKER BROS. ADVISORS LP 1,059 7.3909 1,059 7.3909 7,827
2025-11-11 TRDA BAKER BROS. ADVISORS LP 11,701 7.3909 11,701 7.3909 86,481
2025-11-11 TRDA BAKER BROS. ADVISORS LP 2,795 7.5395 2,795 7.5395 21,073
2025-11-11 TRDA BAKER BROS. ADVISORS LP 30,879 7.5395 30,879 7.5395 232,812
2025-11-10 TRDA BAKER BROS. ADVISORS LP 2,296 7.2139 2,296 7.2139 16,563
2025-11-10 TRDA BAKER BROS. ADVISORS LP 25,364 7.2139 25,364 7.2139 182,973
2025-11-10 TRDA BAKER BROS. ADVISORS LP 267 7.2244 267 7.2244 1,929
2025-11-10 TRDA BAKER BROS. ADVISORS LP 2,947 7.2244 2,947 7.2244 21,290
2022-06-06 TRDA BAKER BROS. ADVISORS LP 921 6.3537 921 6.3537 5,852
2022-06-06 TRDA BAKER BROS. ADVISORS LP 7,815 6.3537 7,815 6.3537 49,654
2022-06-06 TRDA BAKER BROS. ADVISORS LP 3,118 6.4215 3,118 6.4215 20,022
2022-06-06 TRDA BAKER BROS. ADVISORS LP 26,450 6.4215 26,450 6.4215 169,849
2022-06-02 TRDA BAKER BROS. ADVISORS LP 279 5.8202 279 5.8202 1,624
2022-06-02 TRDA BAKER BROS. ADVISORS LP 2,364 5.8202 2,364 5.8202 13,759
2022-05-24 TRDA BAKER BROS. ADVISORS LP 179 5.9300 179 5.9300 1,061
2022-05-24 TRDA BAKER BROS. ADVISORS LP 1,521 5.9300 1,521 5.9300 9,020
2022-05-24 TRDA BAKER BROS. ADVISORS LP 2,334 5.7415 2,334 5.7415 13,401
2022-05-24 TRDA BAKER BROS. ADVISORS LP 19,789 5.7415 19,789 5.7415 113,619
2022-05-23 TRDA BAKER BROS. ADVISORS LP 827 5.9874 827 5.9874 4,952
2022-05-23 TRDA BAKER BROS. ADVISORS LP 7,010 5.9874 7,010 5.9874 41,972
2022-05-20 TRDA BAKER BROS. ADVISORS LP 883 5.8409 883 5.8409 5,158
2022-05-20 TRDA BAKER BROS. ADVISORS LP 7,248 5.8409 7,248 5.8409 42,335
2022-05-20 TRDA BAKER BROS. ADVISORS LP 946 5.8421 946 5.8421 5,527
2022-05-20 TRDA BAKER BROS. ADVISORS LP 7,772 5.8421 7,772 5.8421 45,405
2022-05-18 TRDA BAKER BROS. ADVISORS LP 84 5.9180 84 5.9180 497
2022-05-18 TRDA BAKER BROS. ADVISORS LP 692 5.9180 692 5.9180 4,095
2022-05-18 TRDA BAKER BROS. ADVISORS LP 3,654 6.0000 3,654 6.0000 21,924
2022-05-18 TRDA BAKER BROS. ADVISORS LP 30,003 6.0000 30,003 6.0000 180,018
2022-05-17 TRDA BAKER BROS. ADVISORS LP 2,010 6.1301 2,010 6.1301 12,322
2022-05-17 TRDA BAKER BROS. ADVISORS LP 16,501 6.1301 16,501 6.1301 101,153
2022-05-16 TRDA BAKER BROS. ADVISORS LP 2,063 5.8259 2,063 5.8259 12,019
2022-05-16 TRDA BAKER BROS. ADVISORS LP 16,937 5.8259 16,937 5.8259 98,673

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

TRDA / Entrada Therapeutics, Inc. Insider Trades
TRDA / Entrada Therapeutics, Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

TRDA / Entrada Therapeutics, Inc. Insider Trades
VTVT / vTv Therapeutics Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

VTVT / vTv Therapeutics Inc. Insider Trades
VTVT / vTv Therapeutics Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

VTVT / vTv Therapeutics Inc. Insider Trades
XOMAO / XOMA Royalty Corporation - Preferred Stock內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
2013-08-19 XOMA BAKER BROS. ADVISORS LP 882,323 3.6200 44,116 72.4000 3,194,009 197 188.8 5,135,092 160.77
2013-08-19 XOMA BAKER BROS. ADVISORS LP 1,854,058 3.6200 92,703 72.4000 6,711,690
2013-08-19 XOMA BAKER BROS. ADVISORS LP 21,410 3.6200 1,070 72.4000 77,504
2012-10-29 XOMA BAKER JULIAN 336,639 3.0000 16,832 60.0000 1,009,917
2012-10-29 XOMA BAKER JULIAN 4,282,419 3.0000 214,121 60.0000 12,847,257
2012-10-29 XOMA BAKER JULIAN 103,608 3.0000 5,180 60.0000 310,824

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

XOMAO / XOMA Royalty Corporation - Preferred Stock Insider Trades
XOMAO / XOMA Royalty Corporation - Preferred Stock內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
2015-07-22 XOMA BAKER BROS. ADVISORS LP 1,359,253 1.0925 67,963 21.8500 1,484,984 341 9.01 -872,645 -58.76
2015-07-22 XOMA BAKER BROS. ADVISORS LP 9,411,311 1.0925 470,566 21.8500 10,281,857
2015-07-22 XOMA BAKER BROS. ADVISORS LP 229,436 1.0925 11,472 21.8500 250,659
2015-01-06 XOMA BAKER BROS. ADVISORS LP 118,571 3.8600 5,929 77.2000 457,684
2015-01-06 XOMA BAKER BROS. ADVISORS LP 859,988 3.8600 42,999 77.2000 3,319,554
2015-01-06 XOMA BAKER BROS. ADVISORS LP 21,441 3.8600 1,072 77.2000 82,762
2015-01-05 XOMA BAKER BROS. ADVISORS LP 118,652 3.8115 5,933 76.2300 452,242
2015-01-05 XOMA BAKER BROS. ADVISORS LP 863,100 3.8115 43,155 76.2300 3,289,706
2015-01-05 XOMA BAKER BROS. ADVISORS LP 21,548 3.8115 1,077 76.2300 82,130
2015-01-02 XOMA BAKER BROS. ADVISORS LP 25,092 3.5537 1,255 71.0740 89,169
2015-01-02 XOMA BAKER BROS. ADVISORS LP 182,454 3.5537 9,123 71.0740 648,387
2015-01-02 XOMA BAKER BROS. ADVISORS LP 4,554 3.5537 228 71.0740 16,184
2014-12-30 XOMA BAKER BROS. ADVISORS LP 46,362 3.6495 2,318 72.9900 169,198
2014-12-30 XOMA BAKER BROS. ADVISORS LP 337,123 3.6495 16,856 72.9900 1,230,330
2014-12-30 XOMA BAKER BROS. ADVISORS LP 8,415 3.6495 421 72.9900 30,711
2014-12-29 XOMA BAKER BROS. ADVISORS LP 26,137 3.6762 1,307 73.5240 96,085
2014-12-29 XOMA BAKER BROS. ADVISORS LP 190,117 3.6762 9,506 73.5240 698,908
2014-12-29 XOMA BAKER BROS. ADVISORS LP 4,746 3.6762 237 73.5240 17,447
2014-12-26 XOMA BAKER BROS. ADVISORS LP 15,420 3.7106 771 74.2120 57,217
2014-12-26 XOMA BAKER BROS. ADVISORS LP 112,855 3.7106 5,643 74.2120 418,760
2014-12-26 XOMA BAKER BROS. ADVISORS LP 2,825 3.7106 141 74.2120 10,482
2014-12-19 XOMA BAKER BROS. ADVISORS LP 88,937 4.2085 4,447 84.1700 374,291
2014-12-19 XOMA BAKER BROS. ADVISORS LP 647,781 4.2085 32,389 84.1700 2,726,186
2014-12-19 XOMA BAKER BROS. ADVISORS LP 16,182 4.2085 809 84.1700 68,102
2014-12-18 XOMA BAKER BROS. ADVISORS LP 19,599 4.2890 980 85.7800 84,060
2014-12-18 XOMA BAKER BROS. ADVISORS LP 142,543 4.2890 7,127 85.7800 611,367
2014-12-18 XOMA BAKER BROS. ADVISORS LP 3,558 4.2890 178 85.7800 15,260
2014-12-17 XOMA BAKER BROS. ADVISORS LP 81,109 4.3090 4,055 86.1800 349,499
2014-12-17 XOMA BAKER BROS. ADVISORS LP 590,638 4.3090 29,532 86.1800 2,545,059
2014-12-17 XOMA BAKER BROS. ADVISORS LP 14,753 4.3090 738 86.1800 63,571
2014-12-16 XOMA BAKER BROS. ADVISORS LP 37,592 4.2709 1,880 85.4180 160,552
2014-12-16 XOMA BAKER BROS. ADVISORS LP 274,734 4.2709 13,737 85.4180 1,173,361
2014-12-16 XOMA BAKER BROS. ADVISORS LP 6,874 4.2709 344 85.4180 29,358
2014-12-15 XOMA BAKER BROS. ADVISORS LP 54,396 4.4502 2,720 89.0040 242,073
2014-12-15 XOMA BAKER BROS. ADVISORS LP 396,496 4.4502 19,825 89.0040 1,764,486
2014-12-15 XOMA BAKER BROS. ADVISORS LP 9,908 4.4502 495 89.0040 44,093
2014-12-12 XOMA BAKER BROS. ADVISORS LP 29,960 4.7140 1,498 94.2800 141,231
2014-12-12 XOMA BAKER BROS. ADVISORS LP 218,383 4.7140 10,919 94.2800 1,029,457
2014-12-12 XOMA BAKER BROS. ADVISORS LP 5,457 4.7140 273 94.2800 25,724
2014-12-09 XOMA BAKER BROS. ADVISORS LP 46,383 4.6159 2,319 92.3180 214,099
2014-12-09 XOMA BAKER BROS. ADVISORS LP 337,541 4.6159 16,877 92.3180 1,558,056
2014-12-09 XOMA BAKER BROS. ADVISORS LP 8,429 4.6159 421 92.3180 38,907
2014-12-04 XOMA BAKER BROS. ADVISORS LP 153,618 4.5457 7,681 90.9140 698,301
2014-12-04 XOMA BAKER BROS. ADVISORS LP 1,122,584 4.5457 56,129 90.9140 5,102,930
2014-12-04 XOMA BAKER BROS. ADVISORS LP 28,086 4.5457 1,404 90.9140 127,671
2014-12-03 XOMA BAKER BROS. ADVISORS LP 69,153 4.8402 3,458 96.8040 334,714
2014-12-03 XOMA BAKER BROS. ADVISORS LP 486,800 4.8402 24,340 96.8040 2,356,209
2014-12-03 XOMA BAKER BROS. ADVISORS LP 11,965 4.8402 598 96.8040 57,913
2014-12-02 XOMA BAKER BROS. ADVISORS LP 60,883 5.3591 3,044 107.1820 326,278
2014-12-02 XOMA BAKER BROS. ADVISORS LP 428,583 5.3591 21,429 107.1820 2,296,819
2014-12-02 XOMA BAKER BROS. ADVISORS LP 10,534 5.3591 527 107.1820 56,453

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

XOMAO / XOMA Royalty Corporation - Preferred Stock Insider Trades
ZYME / Zymeworks Inc.內部人士買入 - 短期收益分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士購買的盈利情況。這種分析有助於了解內部人士是否持續產生異常的回報，以及是否值得跟踪。該分析基於每筆交易後一年的情況，結果僅為理論值。

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最高利潤的
天數		 達到最高利潤時的
價格		 最高
淨利 ($)		 最高回報率（%）
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

ZYME / Zymeworks Inc. Insider Trades
ZYME / Zymeworks Inc.內部人士賣出 - 短期虧損分析

在這一部分，我們分析了在 ACAD / ACADIA Pharmaceuticals Inc. 中進行的每筆非計劃的公開市場內部人士賣出所達成的短期虧損規避。如果存在持續的虧損規避模式，可能表明未來的內部人士賣出交易預示著價格的下跌。該分析基於每筆交易後一年的情況，

以下表格顯示了最近的自動交易計劃之外的公開市場購買。

交易日期 證券代碼 內部人士 報告
股數		 Reported
價格		 經調整
股數		 經調整
價格		 成本基礎 達到最低利潤的
天數		 達到最低利潤時的
價格		 避免的
最高損失金額($)		 避免的
最高損失率($)
當前未知該內部人士及證券組合進行過任何未預先計劃的公開市場交易。

經調整價格 已按拆股調整。經調整股數 已按拆股調整。

ZYME / Zymeworks Inc. Insider Trades
歷史內部人交易

該表格顯示了由 Felix Baker 進行的所有內幕交易的完整列表，這些交易已向美國證券交易委員會（SEC）披露。

呈報日期 交易日期 表格 證券代碼 證券 代碼 10b5-1 股份 剩餘股份 %
變化		 每股
股價		 交易
金額		 剩餘
金額
2026-06-05 2026-06-03 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 6,408 3,422,366 0.19
2026-06-05 2026-06-03 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 6,408 343,275 1.90
2026-06-02 2026-05-29 4 KNSA Kiniksa Pharmaceuticals International, plc
Class A Ordinary Shares 		A - Award 6,078 2,744,894 0.22
2026-06-02 2026-05-29 4 KNSA Kiniksa Pharmaceuticals International, plc
Class A Ordinary Shares 		A - Award 6,078 143,277 4.43
2026-06-02 2026-05-29 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 18,622 39,384,587 0.05
2026-06-02 2026-05-29 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 18,622 3,677,357 0.51
2026-05-27 2026-05-22 4 ONC BeOne Medicines Ltd.
Ordinary Shares 		S - Sale -2,756 142,570 -1.90 23.79 -65,567 3,391,812
2026-05-27 2026-05-22 4 ONC BeOne Medicines Ltd.
Ordinary Shares 		S - Sale -2,756 142,566 -1.90 23.79 -65,567 3,391,716
2026-05-27 2026-05-22 4 ONC BeOne Medicines Ltd.
Ordinary Shares 		S - Sale -2,743 145,326 -1.85 23.85 -65,424 3,466,199
2026-05-27 2026-05-22 4 ONC BeOne Medicines Ltd.
Ordinary Shares 		S - Sale -2,743 145,322 -1.85 23.85 -65,424 3,466,104
2026-05-11 2026-05-08 4 INCY INCYTE CORP
Common Stock 		M - Exercise 15,000 28,203,718 0.05 84.53 1,267,950 2,384,060,283
2026-05-11 2026-05-08 4 INCY INCYTE CORP
Common Stock 		M - Exercise 15,000 2,833,039 0.53 84.53 1,267,950 239,476,787
2026-04-02 2026-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 421 28,188,718 0.00
2026-04-02 2026-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 421 2,818,039 0.01
2026-01-06 2026-01-02 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		A - Award 19,000 10,018,674 0.19
2026-01-06 2026-01-02 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		A - Award 19,000 10,018,674 0.19
2026-01-05 2025-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 328 28,188,297 0.00
2026-01-05 2025-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 328 28,188,297 0.00
2025-12-19 2025-12-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,391,268 18,358,772 14.98 23.00 54,999,164 422,251,756
2025-12-19 2025-12-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 217,428 1,560,414 16.19 23.00 5,000,844 35,889,522
2025-12-11 2025-12-11 4 KYMR Kymera Therapeutics, Inc.
Common Stock 		P - Purchase 1,838,621 7,955,916 30.06 86.00 158,121,406 684,208,776
2025-12-11 2025-12-11 4 KYMR Kymera Therapeutics, Inc.
Common Stock 		P - Purchase 167,192 701,326 31.30 86.00 14,378,512 60,314,036
2025-11-24 2025-11-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 13,082 4,691,392 0.28 9.07 118,690 42,564,061
2025-11-24 2025-11-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 1,186 381,338 0.31 9.07 10,760 3,459,803
2025-11-24 2025-11-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 13,386 4,678,310 0.29 9.07 121,395 42,426,658
2025-11-24 2025-11-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 1,213 380,152 0.32 9.07 11,000 3,447,522
2025-11-12 2025-11-12 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 11,494 4,664,924 0.25 7.95 91,431 37,108,071
2025-11-12 2025-11-12 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 1,040 378,939 0.28 7.95 8,273 3,014,346
2025-11-12 2025-11-12 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 80,881 4,653,430 1.77 7.73 625,331 35,977,994
2025-11-12 2025-11-12 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 7,321 377,899 1.98 7.73 56,602 2,921,726
2025-11-12 2025-11-11 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 30,879 4,572,549 0.68 7.54 232,812 34,474,733
2025-11-12 2025-11-11 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,795 370,578 0.76 7.54 21,073 2,793,973
2025-11-12 2025-11-11 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 11,701 4,541,670 0.26 7.39 86,481 33,567,029
2025-11-12 2025-11-11 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 1,059 367,783 0.29 7.39 7,827 2,718,247
2025-11-12 2025-11-10 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,947 4,529,969 0.07 7.22 21,290 32,726,308
2025-11-12 2025-11-10 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 267 366,724 0.07 7.22 1,929 2,649,361
2025-11-12 2025-11-10 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 25,364 4,527,022 0.56 7.21 182,973 32,657,484
2025-11-12 2025-11-10 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,296 366,457 0.63 7.21 16,563 2,643,584
2025-10-02 2025-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 388 28,187,969 0.00
2025-10-02 2025-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 388 2,817,290 0.01
2025-10-02 2025-10-01 4 KALA KALA BIO, Inc.
Common Stock 		S - Sale -462,967 425,006 -52.14 1.38 -640,654 588,123
2025-10-02 2025-10-01 4 KALA KALA BIO, Inc.
Common Stock 		S - Sale -50,640 46,480 -52.14 1.38 -70,076 64,319
2025-10-02 2025-09-30 4 KALA KALA BIO, Inc.
Common Stock 		S - Sale -195,425 887,973 -18.04 1.60 -311,879 1,417,116
2025-10-02 2025-09-30 4 KALA KALA BIO, Inc.
Common Stock 		S - Sale -21,376 97,120 -18.04 1.60 -34,114 154,994
2025-09-10 2025-09-08 4 CELC Celcuity Inc.
Common Stock 		P - Purchase 4,212 7,211,484 0.06 58.02 244,395 418,436,263
2025-09-10 2025-09-08 4 CELC Celcuity Inc.
Common Stock 		P - Purchase 388 704,308 0.06 58.02 22,513 40,866,486
2025-09-10 2025-09-08 4 CELC Celcuity Inc.
Common Stock 		P - Purchase 151,524 7,207,272 2.15 56.22 8,518,679 405,192,832
2025-09-10 2025-09-08 4 CELC Celcuity Inc.
Common Stock 		P - Purchase 13,976 703,920 2.03 56.22 785,731 39,574,382
2025-09-05 2025-09-03 4 VTVT vTv Therapeutics Inc.
Common Stock 		A - Award 46,692 135,946 52.31
2025-09-05 2025-09-03 4 VTVT vTv Therapeutics Inc.
Common Stock 		A - Award 4,308 12,368 53.45
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 10,128 1,859,091 0.55 372.16 3,769,209 691,874,287
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 933 194,625 0.48 372.16 347,223 72,431,115
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,494 1,848,963 0.30 371.00 2,038,301 685,974,518
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 506 193,692 0.26 371.00 187,729 71,860,700
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,747 1,843,469 0.15 369.34 1,014,563 680,857,623
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 253 193,186 0.13 369.34 93,442 71,350,351
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,419 1,840,722 0.08 368.84 523,384 678,931,902
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 131 192,933 0.07 368.84 48,318 71,161,408
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,798 1,839,303 0.26 367.77 1,764,565 676,442,304
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 442 192,802 0.23 367.77 162,555 70,906,984
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,289 1,834,505 0.12 366.30 838,459 671,977,714
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 211 192,360 0.11 366.30 77,289 70,461,314
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,772 1,832,216 0.15 363.75 1,008,308 666,463,806
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 255 192,149 0.13 363.75 92,756 69,893,699
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,587 1,829,444 0.31 362.39 2,024,662 662,968,735
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 515 191,894 0.27 362.39 186,630 69,540,102
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,443 1,823,857 0.30 361.37 1,966,957 659,093,770
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 502 191,379 0.26 361.37 181,410 69,159,318
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 8,514 1,818,414 0.47 359.39 3,059,873 653,525,445
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 784 190,877 0.41 359.39 281,764 68,599,877
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,472 1,809,900 0.14 358.21 885,495 648,324,279
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 228 190,093 0.12 358.21 81,672 68,093,214
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 8,328 1,807,428 0.46 357.02 2,973,289 645,293,728
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 767 189,865 0.41 357.02 273,837 67,786,210
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 916 1,799,100 0.05 355.00 325,180 638,680,500
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 84 189,098 0.04 355.00 29,820 67,129,790
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,923 1,798,184 0.11 353.88 680,503 636,333,262
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 177 189,014 0.09 353.88 62,636 66,887,424
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 9,362 1,947,968 0.48 392.24 3,672,178 764,076,617
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 862 202,813 0.43 392.24 338,113 79,551,959
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,506 1,938,606 0.13 389.89 977,059 755,838,828
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 231 201,951 0.11 389.89 90,064 78,738,231
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 366 1,936,100 0.02 389.00 142,374 753,142,900
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 34 201,720 0.02 389.00 13,226 78,469,080
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,441 1,935,734 0.23 387.07 1,718,969 749,260,688
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 409 201,686 0.20 387.07 158,311 78,066,197
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 13,545 1,931,293 0.71 385.06 5,215,601 743,658,468
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,248 201,277 0.62 385.06 480,552 77,503,178
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,049 1,917,748 0.21 383.79 1,553,954 736,007,135
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 373 200,029 0.19 383.79 143,153 76,768,570
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,838 1,913,699 0.15 382.82 1,086,447 732,604,739
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 262 199,656 0.13 382.82 100,299 76,432,569
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,136 1,910,861 0.06 382.29 434,280 730,501,332
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 105 199,394 0.05 382.29 40,140 76,226,153
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 9,477 1,909,725 0.50 381.12 3,611,889 727,837,448
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 873 199,289 0.44 381.12 332,719 75,953,343
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,919 1,900,248 0.10 380.78 730,717 723,576,433
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 176 198,416 0.09 380.78 67,017 75,552,844
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,209 1,898,329 0.28 380.44 1,981,694 722,193,641
2025-08-20 2025-08-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 480 198,240 0.24 380.44 182,610 75,417,732
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7,325 1,893,120 0.39 374.43 2,742,728 708,848,115
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 675 197,760 0.34 374.43 252,743 74,048,028
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 26,704 1,885,795 1.44 372.87 9,957,102 703,155,062
2025-08-20 2025-08-18 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,460 197,085 1.26 372.87 917,258 73,486,946
2025-08-18 2025-08-14 4 IGMS IGM Biosciences, Inc.
Common Stock 		U - Other -3,763,362 0 -100.00
2025-08-18 2025-08-14 4 IGMS IGM Biosciences, Inc.
Common Stock 		U - Other -357,048 0 -100.00
2025-08-01 3 CELC Celcuity Inc.
Common Stock 		689,944
2025-08-01 3 CELC Celcuity Inc.
Common Stock 		7,055,748
2025-07-02 2025-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 492 28,187,581 0.00
2025-07-02 2025-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 492 28,187,581 0.00
2025-07-02 2025-06-30 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 953 3,763,362 0.03
2025-07-02 2025-06-30 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 953 3,763,362 0.03
2025-06-30 2025-06-30 4 KYMR Kymera Therapeutics, Inc.
Common Stock 		P - Purchase 600,309 6,117,295 10.88 44.00 26,413,596 269,160,980
2025-06-30 2025-06-30 4 KYMR Kymera Therapeutics, Inc.
Common Stock 		P - Purchase 55,191 534,134 11.52 44.00 2,428,404 23,501,896
2025-06-24 2025-06-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		A - Award 1,430 1,796,261 0.08
2025-06-24 2025-06-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		A - Award 1,430 1,796,261 0.08
2025-06-12 2025-06-10 4 INCY INCYTE CORP
Common Stock 		A - Award 2,518 28,187,089 0.01
2025-06-12 2025-06-10 4 INCY INCYTE CORP
Common Stock 		A - Award 2,518 28,187,089 0.01
2025-06-05 3 DNLI Denali Therapeutics Inc.
Common Stock 		326,302
2025-06-05 3 DNLI Denali Therapeutics Inc.
Common Stock 		3,405,393
2025-06-05 2025-06-03 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 10,565 3,415,958 0.31
2025-06-05 2025-06-03 4 DNLI Denali Therapeutics Inc.
Common Stock 		A - Award 10,565 3,415,958 0.31
2025-06-05 2025-06-03 4 KNSA Kiniksa Pharmaceuticals International, plc
Class A Ordinary Shares 		A - Award 8,397 2,738,816 0.31
2025-06-05 2025-06-03 4 KNSA Kiniksa Pharmaceuticals International, plc
Class A Ordinary Shares 		A - Award 8,397 2,738,816 0.31
2025-06-02 2025-05-29 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 16,214 39,365,965 0.04
2025-06-02 2025-05-29 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 16,214 39,365,965 0.04
2025-05-22 2025-05-21 4 ONC BeiGene, Ltd.
Ordinary Shares 		A - Award 21,970 148,069 17.42
2025-05-22 2025-05-21 4 ONC BeiGene, Ltd.
Ordinary Shares 		A - Award 21,970 148,065 17.42
2025-04-02 2025-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 487 28,184,571 0.00
2025-04-02 2025-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 487 2,813,892 0.02
2025-04-02 2025-03-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 953 3,762,409 0.03
2025-04-02 2025-03-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 953 356,095 0.27
2025-03-19 2025-03-17 4 IMCR Immunocore Holdings plc
American Depositary Shares 		P - Purchase 92,349 2,144,060 4.50 29.56 2,729,864 63,379,057
2025-03-19 2025-03-17 4 IMCR Immunocore Holdings plc
American Depositary Shares 		P - Purchase 8,589 178,596 5.05 29.56 253,893 5,279,351
2025-03-19 2025-03-17 4 IMCR Immunocore Holdings plc
American Depositary Shares 		P - Purchase 646,290 2,051,711 45.99 29.74 19,221,699 61,021,168
2025-03-19 2025-03-17 4 IMCR Immunocore Holdings plc
American Depositary Shares 		P - Purchase 60,110 170,007 54.70 29.74 1,787,768 5,056,280
2025-03-07 3 REPL Replimune Group, Inc.
Common Stock 		929,241
2025-03-07 3 REPL Replimune Group, Inc.
Common Stock 		10,116,095
2025-02-28 2025-02-28 4 ONC BeiGene, Ltd.
American Depositary Shares 		S - Sale -671,976 8,068,411 -7.69 260.00 -174,713,760 2,097,786,860
2025-02-28 2025-02-28 4 ONC BeiGene, Ltd.
American Depositary Shares 		S - Sale -60,851 730,642 -7.69 260.00 -15,821,260 189,966,920
2025-02-14 3 SERA SERA PROGNOSTICS, INC.
Common Stock 		432,434
2025-02-14 3 SERA SERA PROGNOSTICS, INC.
Common Stock 		5,065,736
2025-01-06 2025-01-02 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		A - Award 4,400 9,999,674 0.04
2025-01-06 2025-01-02 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		A - Award 4,400 918,483 0.48
2025-01-03 2024-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 446 28,184,084 0.00
2025-01-03 2024-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 446 28,184,084 0.00
2025-01-03 2024-12-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 3,761,456 0.05
2025-01-03 2024-12-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 355,142 0.56
2024-12-31 2024-12-30 4 KALA KALA BIO, Inc.
Common Stock 		P - Purchase 279,939 1,083,398 34.84 6.44 1,802,807 6,977,083
2024-12-31 2024-12-30 4 KALA KALA BIO, Inc.
Common Stock 		P - Purchase 30,620 118,496 34.84 6.44 197,193 763,114
2024-12-17 2024-12-16 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 457,631 9,995,274 4.80 15.34 7,020,883 153,345,495
2024-12-17 2024-12-16 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 42,369 914,083 4.86 15.34 650,017 14,023,679
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 566,814 9,537,643 6.32 13.80 7,824,300 131,657,624
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 52,656 871,714 6.43 13.80 726,863 12,033,140
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 244,587 8,970,829 2.80 13.72 3,356,761 123,117,451
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 22,722 819,058 2.85 13.72 311,841 11,240,916
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 59,995 8,726,242 0.69 13.63 817,660 118,928,207
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 5,573 796,336 0.70 13.63 75,953 10,853,104
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 30,241 8,666,247 0.35 13.50 408,190 116,976,135
2024-12-17 2024-12-13 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		P - Purchase 2,809 790,763 0.36 13.50 37,916 10,673,640
2024-12-10 2024-12-09 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -916,964 8,740,387 -9.49 186.50 -171,013,786 1,630,082,176
2024-12-10 2024-12-09 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -83,036 791,493 -9.49 186.50 -15,486,214 147,613,444
2024-12-10 2024-12-09 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -33,943 9,657,351 -0.35 208.01 -7,060,609 2,008,861,314
2024-12-10 2024-12-09 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -3,074 874,529 -0.35 208.01 -639,434 181,914,013
2024-10-08 2024-10-04 4 KNSA Kiniksa Pharmaceuticals International, plc
Class A Ordinary Shares 		A - Award 4,730 2,730,419 0.17
2024-10-08 2024-10-04 4 KNSA Kiniksa Pharmaceuticals International, plc
Class A Ordinary Shares 		A - Award 4,730 2,730,419 0.17
2024-10-02 2024-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 496 28,183,638 0.00
2024-10-02 2024-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 496 2,812,959 0.02
2024-10-02 2024-09-30 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 3,759,462 0.05
2024-10-02 2024-09-30 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 353,148 0.57
2024-08-22 2024-08-20 4 KYMR Kymera Therapeutics, Inc.
Common Stock 		P - Purchase 1 5,516,986 0.00 46.41 46 256,043,320
2024-07-02 2024-06-28 4 INCY INCYTE CORP
Common Stock 		A - Award 537 28,183,142 0.00
2024-07-02 2024-06-28 4 INCY INCYTE CORP
Common Stock 		A - Award 537 28,183,142 0.00
2024-07-02 2024-06-28 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 3,757,468 0.05
2024-07-02 2024-06-28 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 3,757,468 0.05
2024-06-28 3 KALA KALA BIO, Inc.
Common Stock 		87,876
2024-06-28 3 KALA KALA BIO, Inc.
Common Stock 		803,459
2024-06-27 2024-06-25 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		A - Award 1,428 1,794,831 0.08
2024-06-27 2024-06-25 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		A - Award 1,428 1,794,831 0.08
2024-06-20 2024-06-17 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		C - Conversion 2,186,686 8,636,006 33.91
2024-06-20 2024-06-17 4 BCYC BICYCLE THERAPEUTICS PLC
American Depositary Shares 		C - Conversion 196,098 787,954 33.13
2024-06-14 2024-06-12 4 INCY INCYTE CORP
Common Stock 		D - Sale to Issuer -5,283,206 28,182,605 -15.79 60.00 -316,992,360 1,690,956,300
2024-06-14 2024-06-12 4 INCY INCYTE CORP
Common Stock 		D - Sale to Issuer -175,977 2,811,926 -5.89 60.00 -10,558,620 168,715,560
2024-06-14 2024-06-12 4 INCY INCYTE CORP
Common Stock 		A - Award 2,830 33,465,811 0.01
2024-06-14 2024-06-12 4 INCY INCYTE CORP
Common Stock 		A - Award 2,830 33,465,811 0.01
2024-06-07 2024-06-05 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 32,682 126,099 34.99
2024-06-07 2024-06-05 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 32,682 126,099 34.99
2024-06-07 2024-06-05 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		A - Award 6,346 2,725,689 0.23
2024-06-07 2024-06-05 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		A - Award 6,346 2,725,689 0.23
2024-05-31 2024-05-29 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 18,774 39,349,751 0.05
2024-05-31 2024-05-29 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 18,774 39,349,751 0.05
2024-05-29 3 IMCR Immunocore Holdings plc
American Depositary Shares 		109,897
2024-05-29 3 IMCR Immunocore Holdings plc
American Depositary Shares 		1,405,421
2024-05-09 2024-05-07 4 INCY INCYTE CORP
Common Stock 		M - Exercise 15,000 33,462,981 0.04 49.01 735,150 1,640,020,699
2024-05-09 2024-05-07 4 INCY INCYTE CORP
Common Stock 		M - Exercise 15,000 2,985,073 0.51 49.01 735,150 146,298,428
2024-04-22 2024-04-18 4 BCYC BICYCLE THERAPEUTICS plc
American Depositary Shares 		A - Award 12,000 6,449,320 0.19
2024-04-22 2024-04-18 4 BCYC BICYCLE THERAPEUTICS plc
American Depositary Shares 		A - Award 12,000 6,449,320 0.19
2024-04-18 3 BCYC BICYCLE THERAPEUTICS plc
American Depositary Shares 		579,856
2024-04-18 3 BCYC BICYCLE THERAPEUTICS plc
American Depositary Shares 		6,437,320
2024-04-01 2024-03-29 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 3,755,474 0.05
2024-04-01 2024-03-29 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 1,994 3,755,474 0.05
2024-04-01 2024-03-28 4 INCY INCYTE CORP
Common Stock 		A - Award 543 33,447,981 0.00
2024-04-01 2024-03-28 4 INCY INCYTE CORP
Common Stock 		A - Award 543 2,970,073 0.02
2024-03-28 2024-03-28 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 89,407 3,753,480 2.44 9.62 860,042 36,106,226
2024-03-28 2024-03-28 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 8,066 347,166 2.38 9.62 77,590 3,339,529
2024-03-28 2024-03-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 8,439 3,664,073 0.23 9.27 78,207 33,956,064
2024-03-28 2024-03-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 761 339,100 0.22 9.27 7,052 3,142,541
2024-03-28 2024-03-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 17,101 3,655,634 0.47 9.22 157,683 33,707,504
2024-03-28 2024-03-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 1,543 338,339 0.46 9.22 14,228 3,119,722
2024-03-28 2024-03-26 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 247,656 3,638,533 7.30 8.26 2,046,159 30,061,923
2024-03-28 2024-03-26 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 22,344 336,796 7.11 8.26 184,608 2,782,642
2024-03-07 3 VTVT vTv Therapeutics Inc.
Common Stock 		12,836
2024-03-07 3 VTVT vTv Therapeutics Inc.
Common Stock 		142,135
2024-03-07 2024-03-05 4 VTVT vTv Therapeutics Inc.
Common Stock 		D - Sale to Issuer -52,881 89,254 -37.20
2024-03-07 2024-03-05 4 VTVT vTv Therapeutics Inc.
Common Stock 		D - Sale to Issuer -4,776 8,060 -37.21
2024-01-03 2023-12-29 4 INCY INCYTE CORP
Common Stock 		A - Award 556 33,447,438 0.00
2024-01-03 2023-12-29 4 INCY INCYTE CORP
Common Stock 		A - Award 556 33,447,438 0.00
2024-01-03 2023-12-29 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 3,390,877 0.02
2024-01-03 2023-12-29 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 3,390,877 0.02
2023-12-18 2023-12-14 4 SGEN Seagen Inc.
Common Stock 		D - Sale to Issuer -42,977,301 0 -100.00 229.00 -9,841,801,929
2023-12-18 2023-12-14 4 SGEN Seagen Inc.
Common Stock 		D - Sale to Issuer -1,731,202 0 -100.00 229.00 -396,445,258
2023-12-18 2023-12-14 4 SGEN Seagen Inc.
Common Stock 		D - Sale to Issuer -23,277 0 -100.00 229.00 -5,330,433
2023-12-18 2023-12-14 4 SGEN Seagen Inc.
Common Stock 		D - Sale to Issuer -23,280 0 -100.00 229.00 -5,331,120
2023-12-15 2023-12-15 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 214,025 3,390,323 6.74 6.60 1,412,565 22,376,132
2023-12-15 2023-12-15 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 17,066 313,898 5.75 6.60 112,636 2,071,727
2023-12-15 2023-12-15 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 52,528 3,176,298 1.68 6.37 334,399 20,220,631
2023-12-15 2023-12-15 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 4,188 296,832 1.43 6.37 26,661 1,889,662
2023-12-15 2023-12-15 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 185 3,123,770 0.01 6.36 1,176 19,851,558
2023-12-15 2023-12-15 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 15 292,644 0.01 6.36 95 1,859,753
2023-12-15 2023-12-14 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 145,749 3,123,585 4.89 6.50 947,602 20,308,300
2023-12-15 2023-12-14 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 11,621 292,629 4.14 6.50 75,555 1,902,557
2023-12-15 2023-12-13 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 71,219 2,977,836 2.45 5.99 426,751 17,843,491
2023-12-15 2023-12-13 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 5,679 281,008 2.06 5.99 34,029 1,683,828
2023-12-15 2023-12-13 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 9,649 2,906,617 0.33 5.76 55,567 16,738,626
2023-12-15 2023-12-13 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 769 275,329 0.28 5.76 4,429 1,585,565
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,857 1,699,129 0.23 221.24 853,330 375,918,358
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 308 178,461 0.17 221.24 68,142 39,483,033
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,408 1,695,272 0.26 220.65 972,645 374,069,565
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 352 178,153 0.20 220.65 77,670 39,310,279
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 15,005 1,690,864 0.90 219.24 3,289,711 370,706,714
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,195 177,801 0.68 219.24 261,993 38,981,269
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,873 1,675,859 0.17 217.91 626,049 365,182,748
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 229 176,606 0.13 217.91 49,901 38,483,825
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 185 1,672,986 0.01 217.90 40,312 364,543,649
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 15 176,377 0.01 217.90 3,268 38,432,548
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,769 1,672,801 0.11 216.67 383,286 362,442,949
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 141 176,362 0.08 216.67 30,550 38,212,055
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 668 1,671,032 0.04 214.72 143,434 358,807,834
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 53 176,221 0.03 214.72 11,380 37,838,578
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 515 1,670,364 0.03 213.80 110,107 357,122,821
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 41 176,168 0.02 213.80 8,766 37,664,613
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 185 1,669,849 0.01 213.62 39,521 356,721,493
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 15 176,127 0.01 213.62 3,204 37,625,130
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 648 1,669,664 0.04 212.04 137,403 354,037,892
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 52 176,112 0.03 212.04 11,026 37,343,035
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 93 1,669,016 0.01 209.76 19,508 350,101,141
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7 176,060 0.00 209.76 1,468 36,931,226
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 370 1,668,923 0.02 208.69 77,216 348,289,710
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 30 176,053 0.02 208.69 6,261 36,740,729
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 648 1,668,553 0.04 206.93 134,092 345,277,176
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 52 176,023 0.03 206.93 10,760 36,424,809
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 708 1,667,905 0.04 205.60 145,565 342,921,268
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 56 175,971 0.03 205.60 11,514 36,179,638
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 93 1,667,197 0.01 205.32 19,095 342,308,888
2023-12-14 2023-12-12 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7 175,915 0.00 205.32 1,437 36,118,868
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,960 1,793,403 0.22 229.86 910,264 412,240,043
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 316 185,979 0.17 229.86 72,637 42,750,007
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,204 1,789,443 0.12 228.79 504,252 409,405,411
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 176 185,663 0.09 228.79 40,267 42,477,708
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 11,602 1,787,239 0.65 227.86 2,643,597 407,234,917
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 925 185,487 0.50 227.86 210,768 42,264,511
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,343 1,775,637 0.08 226.97 304,822 403,018,106
2023-12-14 2023-12-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 107 184,562 0.06 226.97 24,286 41,890,222
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,594 1,774,294 0.32 224.91 1,258,156 399,059,480
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 446 184,455 0.24 224.91 100,311 41,486,088
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 363 1,768,700 0.02 223.94 81,289 396,078,079
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 29 184,009 0.02 223.94 6,494 41,206,497
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 9,262 1,768,337 0.53 222.68 2,062,425 393,766,210
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 738 183,980 0.40 222.68 164,335 40,967,930
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,532 1,759,075 0.26 221.78 1,005,101 390,125,367
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 361 183,242 0.20 221.78 80,062 40,639,173
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,518 1,754,543 0.26 219.87 993,351 385,762,948
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 360 182,881 0.20 219.87 79,151 40,209,168
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 29,738 1,750,025 1.73 218.46 6,496,513 382,307,486
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,373 182,521 1.32 218.46 518,402 39,873,227
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 10,894 1,720,287 0.64 217.52 2,369,611 374,188,571
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 869 180,148 0.48 217.52 189,021 39,184,928
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 10,264 1,709,393 0.60 216.70 2,224,203 370,424,437
2023-12-14 2023-12-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 818 179,279 0.46 216.70 177,260 38,849,652
2023-11-24 2023-11-22 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		X - Other 1,941,607 2,168,818 854.54 0.00 194 217
2023-11-24 2023-11-22 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		X - Other 174,742 196,654 797.47 0.00 17 20
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7,917 1,667,104 0.48 190.14 1,505,308 316,976,653
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 655 175,908 0.37 190.14 124,539 33,446,461
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 15,620 1,659,187 0.95 188.70 2,947,539 313,093,399
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,291 175,253 0.74 188.70 243,615 33,070,749
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 13,505 1,643,567 0.83 188.46 2,545,218 309,754,690
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,117 173,962 0.65 188.46 210,515 32,785,731
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 13,011 1,630,062 0.80 188.32 2,450,273 306,978,492
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,076 172,845 0.63 188.32 202,636 32,550,724
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,712 1,617,051 0.29 187.27 882,420 302,826,273
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 388 171,769 0.23 187.27 72,661 32,167,301
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,124 1,612,339 0.13 187.24 397,706 301,900,642
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 176 171,381 0.10 187.24 32,955 32,090,047
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,385 1,610,215 0.09 186.59 258,431 300,454,847
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 115 171,205 0.07 186.59 21,458 31,945,655
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 647 1,608,830 0.04 186.32 120,547 299,752,540
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 53 171,090 0.03 186.32 9,875 31,876,993
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 369 1,608,183 0.02 183.16 67,586 294,554,798
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 31 171,037 0.02 183.16 5,678 31,327,137
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 146 1,607,814 0.01 185.94 27,148 298,963,688
2023-11-21 2023-11-21 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 12 171,006 0.01 185.94 2,231 31,797,574
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,022 1,607,668 0.19 189.70 573,267 304,971,083
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 250 170,994 0.15 189.70 47,424 32,437,186
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,147 1,604,646 0.07 188.84 216,595 303,014,772
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 95 170,744 0.06 188.84 17,939 32,242,597
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,895 1,603,499 0.31 187.34 917,054 300,407,520
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 405 170,649 0.24 187.34 75,875 31,970,237
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,206 1,598,604 0.08 185.86 224,153 297,124,532
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 100 170,244 0.06 185.86 18,586 31,642,401
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7,010 1,597,398 0.44 183.40 1,285,633 292,962,633
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 579 170,144 0.34 183.40 106,189 31,204,393
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,847 1,590,388 0.12 181.93 336,025 289,339,289
2023-11-21 2023-11-20 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 153 169,565 0.09 181.93 27,835 30,848,960
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 10,715 1,588,541 0.68 175.82 1,883,889 279,293,943
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 903 169,412 0.54 175.82 158,764 29,785,662
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,923 1,577,826 0.31 175.72 865,062 277,253,218
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 415 168,509 0.25 175.72 72,923 29,610,149
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 18,125 1,572,903 1.17 174.87 3,169,606 275,061,098
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,528 168,094 0.92 174.87 267,209 29,395,405
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 978 1,554,778 0.06 174.67 170,827 271,572,762
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 82 166,566 0.05 174.67 14,323 29,094,050
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,660 1,553,800 0.11 173.75 288,422 269,969,798
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 140 166,484 0.08 173.75 24,325 28,926,279
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,151 1,552,140 0.27 173.20 718,960 268,833,131
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 350 166,344 0.21 173.20 60,621 28,811,047
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 461 1,547,989 0.03 171.79 79,195 265,929,030
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 39 165,994 0.02 171.79 6,700 28,516,109
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,107 1,547,528 0.07 168.78 186,842 261,195,645
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 93 165,955 0.06 168.78 15,697 28,010,300
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 646 1,546,421 0.04 167.63 108,289 259,226,552
2023-11-21 2023-11-17 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 54 165,862 0.03 167.63 9,052 27,803,447
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 13,548 1,500,227 0.91 154.78 2,096,961 232,205,285
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,142 161,969 0.71 154.78 176,759 25,069,578
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 8,098 1,486,679 0.55 153.97 1,246,878 228,909,318
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 683 160,827 0.43 153.97 105,164 24,763,112
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,877 1,478,581 0.19 153.25 440,907 226,595,939
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 242 160,144 0.15 153.25 37,087 24,542,436
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 646 1,475,704 0.04 152.21 98,330 224,621,185
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 54 159,902 0.03 152.21 8,219 24,339,147
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 6,022 1,475,058 0.41 152.48 918,235 224,916,844
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 507 159,848 0.32 152.48 77,307 24,373,623
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,542 1,469,036 0.24 154.60 547,582 227,108,412
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 299 159,341 0.19 154.60 46,224 24,633,625
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 26,426 1,465,494 1.84 146.21 3,863,756 214,270,464
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,228 159,042 1.42 146.21 325,757 23,253,594
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,994 1,439,068 0.21 145.98 437,057 210,071,549
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 252 156,814 0.16 145.98 36,786 22,891,316
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 6,369 1,436,074 0.45 145.46 926,430 208,890,175
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 537 156,562 0.34 145.46 78,112 22,773,383
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,291 1,429,705 0.09 142.86 184,429 204,244,082
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 109 156,025 0.07 142.86 15,571 22,289,341
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 10,790 1,428,414 0.76 141.44 1,526,192 202,042,018
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 910 155,916 0.59 141.44 128,715 22,053,539
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,072 1,417,624 0.36 140.90 714,657 199,746,624
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 427 155,006 0.28 140.90 60,165 21,840,717
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,631 1,412,552 0.33 137.69 637,622 194,487,928
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 390 154,579 0.25 137.69 53,697 21,283,287
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,693 1,407,921 0.26 136.91 505,605 192,756,915
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 311 154,189 0.20 136.91 42,579 21,109,846
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,144 1,404,228 0.22 136.18 428,151 191,228,471
2023-11-15 2023-11-13 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 265 153,878 0.17 136.18 36,088 20,955,183
2023-11-15 2023-11-15 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 14,018 1,545,775 0.92 161.97 2,270,439 250,362,994
2023-11-15 2023-11-15 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,181 165,808 0.72 161.97 191,282 26,855,259
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 31,530 1,531,757 2.10 156.42 4,932,061 239,604,170
2023-11-15 2023-11-14 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,658 164,627 1.64 156.42 415,776 25,751,680
2023-11-14 2023-11-14 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -1,008,660 9,691,294 -9.43 180.50 -182,063,130 1,749,278,567
2023-11-14 2023-11-14 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -91,340 877,603 -9.43 180.50 -16,486,870 158,407,342
2023-10-23 2023-10-19 4 BCEL Atreca, Inc.
Class A common stock 		S - Sale -251,902 2,971,128 -7.82 0.40 -101,391 1,195,879
2023-10-23 2023-10-19 4 BCEL Atreca, Inc.
Class A common stock 		S - Sale -22,837 286,893 -7.37 0.40 -9,192 115,474
2023-10-10 2023-10-05 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		X - Other 535,601 1,658,190 47.71
2023-10-10 2023-10-05 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		X - Other 57,049 155,874 57.73
2023-10-03 2023-09-29 4 INCY INCYTE CORP
Common Stock 		A - Award 510 33,446,882 0.00
2023-10-03 2023-09-29 4 INCY INCYTE CORP
Common Stock 		A - Award 510 2,968,974 0.02
2023-10-03 2023-09-29 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 2,896,968 0.02
2023-10-03 2023-09-29 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 274,560 0.20
2023-08-17 2023-08-17 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 61,134 5,612,949 1.10 0.69 42,354 3,888,651
2023-08-17 2023-08-17 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 5,041 494,133 1.03 0.69 3,492 342,335
2023-08-17 2023-08-17 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 93,091 5,551,815 1.71 0.69 64,456 3,844,077
2023-08-17 2023-08-17 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 7,676 489,092 1.59 0.69 5,315 338,647
2023-08-17 2023-08-16 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 4,434 5,458,724 0.08 0.68 3,028 3,727,217
2023-08-17 2023-08-16 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 366 481,416 0.08 0.68 250 328,711
2023-08-17 2023-08-16 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 207,676 5,454,290 3.96 0.68 141,324 3,711,644
2023-08-17 2023-08-16 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 17,124 481,050 3.69 0.68 11,653 327,355
2023-08-17 2023-08-15 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 4,342 5,246,614 0.08 0.66 2,887 3,488,998
2023-08-17 2023-08-15 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 358 463,926 0.08 0.66 238 308,511
2023-08-17 2023-08-15 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 1,740,581 5,242,272 49.71 0.63 1,097,958 3,306,825
2023-08-17 2023-08-15 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 143,519 463,568 44.84 0.63 90,532 292,419
2023-07-05 2023-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 512 33,446,372 0.00
2023-07-05 2023-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 512 33,446,372 0.00
2023-07-05 2023-06-30 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 2,896,414 0.02
2023-07-05 2023-06-30 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 2,896,414 0.02
2023-06-20 3 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		148,821
2023-06-20 3 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		1,396,292
2023-06-20 2023-06-15 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		A - Award 4,792 1,401,084 0.34
2023-06-20 2023-06-15 4 MDGL MADRIGAL PHARMACEUTICALS, INC.
Common Stock 		A - Award 4,792 1,401,084 0.34
2023-06-20 2023-06-15 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 25,844 93,417 38.25
2023-06-20 2023-06-15 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 25,844 93,417 38.25
2023-06-16 2023-06-14 4 INCY INCYTE CORP
Common Stock 		A - Award 2,505 33,445,860 0.01
2023-06-16 2023-06-14 4 INCY INCYTE CORP
Common Stock 		A - Award 2,505 33,445,860 0.01
2023-06-08 2023-06-06 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		A - Award 8,746 2,719,343 0.32
2023-06-08 2023-06-06 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		A - Award 8,746 2,719,343 0.32
2023-06-05 2023-06-01 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 13,304 39,330,977 0.03
2023-06-05 2023-06-01 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 13,304 39,330,977 0.03
2023-06-02 2023-05-31 4 SGEN Seagen Inc.
Common Stock 		A - Award 2,044 42,977,301 0.00
2023-06-02 2023-05-31 4 SGEN Seagen Inc.
Common Stock 		A - Award 2,044 42,977,301 0.00
2023-05-24 2023-05-24 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 259,109 39,317,673 0.66 25.65 6,646,146 1,008,498,312
2023-05-24 2023-05-24 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 24,113 3,610,443 0.67 25.65 618,498 92,607,863
2023-05-24 2023-05-24 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 28,878 39,058,564 0.07 25.51 736,788 996,532,390
2023-05-24 2023-05-24 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,688 3,586,330 0.08 25.51 68,581 91,500,906
2023-05-24 2023-05-24 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 218,171 39,029,686 0.56 25.27 5,513,683 986,369,933
2023-05-24 2023-05-24 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 20,304 3,583,642 0.57 25.27 513,129 90,566,876
2023-05-24 2023-05-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 74,582 38,811,515 0.19 25.54 1,904,824 991,246,093
2023-05-24 2023-05-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 6,941 3,563,338 0.20 25.54 177,273 91,007,653
2023-05-24 2023-05-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 116,672 38,736,933 0.30 25.33 2,955,325 981,214,260
2023-05-24 2023-05-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 10,858 3,556,397 0.31 25.33 275,035 90,084,247
2023-05-24 2023-05-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		M - Exercise 12,500 38,620,261 0.03 17.01 212,625 656,930,640
2023-05-24 2023-05-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		M - Exercise 12,500 38,620,261 0.03 17.01 212,625 656,930,640
2023-05-24 2023-05-22 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 40,632 38,607,761 0.11 24.80 1,007,674 957,472,473
2023-05-24 2023-05-22 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,781 3,533,039 0.11 24.80 93,769 87,619,367
2023-05-24 2023-05-22 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 82,148 38,567,129 0.21 24.46 2,009,373 943,367,402
2023-05-24 2023-05-22 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 7,645 3,529,258 0.22 24.46 187,000 86,327,062
2023-05-05 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		21,912
2023-05-05 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		227,211
2023-05-03 2023-05-02 4 SGEN Seagen Inc.
Common Stock 		G - Gift -209,175 23,277 -89.99
2023-05-03 2023-05-02 4 SGEN Seagen Inc.
Common Stock 		G - Gift -209,175 23,277 -89.99
2023-05-03 2023-05-01 4 SGEN Seagen Inc.
Common Stock 		J - Other 209,175 232,452 898.63
2023-05-03 2023-05-01 4 SGEN Seagen Inc.
Common Stock 		J - Other 209,175 232,452 898.63
2023-05-03 2023-05-01 4 SGEN Seagen Inc.
Common Stock 		J - Other -2,368,357 1,729,158 -57.80
2023-05-03 2023-05-01 4 SGEN Seagen Inc.
Common Stock 		M - Exercise 8,750 42,975,257 0.02 36.70 321,125 1,577,191,932
2023-05-03 2023-05-01 4 SGEN Seagen Inc.
Common Stock 		M - Exercise 8,750 42,975,257 0.02 36.70 321,125 1,577,191,932
2023-04-04 2023-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 429 33,443,355 0.00
2023-04-04 2023-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 429 33,443,355 0.00
2023-04-04 2023-03-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 2,895,860 0.02
2023-04-04 2023-03-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 554 2,895,860 0.02
2023-03-15 2023-03-13 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 33,442,926 0.06 22.74 454,800 760,492,137
2023-03-15 2023-03-13 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 33,442,926 0.06 22.74 454,800 760,492,137
2023-01-17 2023-01-12 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		M - Exercise 15,000 38,484,981 0.04 5.22 78,300 200,891,601
2023-01-17 2023-01-12 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		M - Exercise 15,000 38,484,981 0.04 5.22 78,300 200,891,601
2023-01-04 2022-12-30 4 INCY INCYTE CORP
Common Stock 		A - Award 397 33,422,926 0.00
2023-01-04 2022-12-30 4 INCY INCYTE CORP
Common Stock 		A - Award 397 33,422,926 0.00
2022-10-04 2022-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 457 33,422,529 0.00
2022-10-04 2022-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 457 33,422,529 0.00
2022-07-01 2022-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 433 33,422,072 0.00
2022-07-01 2022-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 433 33,422,072 0.00
2022-06-30 2022-06-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		A - Award 10,000 2,710,597 0.37
2022-06-30 2022-06-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		A - Award 10,000 2,710,597 0.37
2022-06-24 2022-06-22 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 33,384 67,573 97.65
2022-06-24 2022-06-22 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 33,384 67,569 97.66
2022-06-17 2022-06-15 4 INCY INCYTE CORP
Common Stock 		A - Award 2,144 33,421,639 0.01
2022-06-17 2022-06-15 4 INCY INCYTE CORP
Common Stock 		A - Award 2,144 33,421,639 0.01
2022-06-13 2022-06-13 4 DBVT DBV Technologies S.A.
Ordinary Shares 		A - Award 10,622,568 14,575,984 268.69
2022-06-13 2022-06-13 4 DBVT DBV Technologies S.A.
Ordinary Shares 		A - Award 1,252,432 1,585,054 376.53
2022-06-09 2022-06-07 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 17,104 38,469,981 0.04
2022-06-09 2022-06-07 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 17,104 38,469,981 0.04
2022-06-06 2022-06-06 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 26,450 4,501,658 0.59 6.42 169,849 28,907,397
2022-06-06 2022-06-06 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 3,118 364,161 0.86 6.42 20,022 2,338,460
2022-06-06 2022-06-06 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 7,815 4,475,208 0.17 6.35 49,654 28,434,129
2022-06-06 2022-06-06 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 921 361,043 0.26 6.35 5,852 2,293,959
2022-06-06 2022-06-02 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,364 4,467,393 0.05 5.82 13,759 26,001,121
2022-06-06 2022-06-02 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 279 360,122 0.08 5.82 1,624 2,095,982
2022-06-06 2022-06-06 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 170,549 15,967,504 1.08 7.78 1,327,008 124,239,955
2022-06-06 2022-06-06 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 20,108 1,342,986 1.52 7.78 156,456 10,449,505
2022-06-06 2022-06-06 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 101,315 15,796,955 0.65 7.75 785,070 122,407,445
2022-06-06 2022-06-06 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 11,945 1,322,878 0.91 7.75 92,559 10,250,717
2022-06-06 2022-06-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 78,271 15,695,640 0.50 7.95 622,466 124,822,716
2022-06-06 2022-06-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 9,224 1,310,933 0.71 7.95 73,356 10,425,457
2022-06-06 2022-06-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 13,155 15,617,369 0.08 7.93 104,363 123,897,273
2022-06-06 2022-06-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,550 1,301,709 0.12 7.93 12,297 10,326,848
2022-06-06 2022-06-02 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 138,122 15,604,214 0.89 7.68 1,060,680 119,829,441
2022-06-06 2022-06-02 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 16,278 1,300,159 1.27 7.68 125,004 9,984,311
2022-06-06 2022-06-02 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,585 15,466,092 0.07 7.51 79,540 116,218,402
2022-06-06 2022-06-02 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,247 1,283,881 0.10 7.51 9,370 9,647,595
2022-05-27 2022-05-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 88,046 15,455,507 0.57 6.92 609,278 106,952,108
2022-05-27 2022-05-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,386 1,282,634 0.82 6.92 71,871 8,875,827
2022-05-27 2022-05-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 51,082 15,367,461 0.33 6.78 346,367 104,200,606
2022-05-27 2022-05-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,026 1,272,248 0.48 6.78 40,860 8,626,605
2022-05-27 2022-05-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 358 15,316,379 0.00 6.64 2,375 101,624,175
2022-05-27 2022-05-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 42 1,266,222 0.00 6.64 279 8,401,383
2022-05-27 2022-05-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 984 15,316,021 0.01 6.76 6,647 103,459,722
2022-05-27 2022-05-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 116 1,266,180 0.01 6.76 784 8,553,046
2022-05-27 2022-05-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 53,401 15,315,037 0.35 6.75 360,521 103,394,878
2022-05-27 2022-05-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,299 1,266,064 0.50 6.75 42,526 8,547,451
2022-05-27 2022-05-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 29,090 15,261,636 0.19 6.71 195,089 102,350,636
2022-05-27 2022-05-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,432 1,259,765 0.27 6.71 23,016 8,448,488
2022-05-27 2022-05-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 42,250 15,232,546 0.28 6.60 279,002 100,589,641
2022-05-27 2022-05-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,984 1,256,333 0.40 6.60 32,912 8,296,321
2022-05-27 2022-05-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 48,222 15,190,296 0.32 6.53 315,058 99,245,799
2022-05-27 2022-05-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,688 1,251,349 0.46 6.53 37,163 8,175,689
2022-05-24 2022-05-24 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 19,789 4,465,029 0.45 5.74 113,619 25,635,964
2022-05-24 2022-05-24 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,334 359,843 0.65 5.74 13,401 2,066,039
2022-05-24 2022-05-24 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 1,521 4,445,240 0.03 5.93 9,020 26,360,273
2022-05-24 2022-05-24 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 179 357,509 0.05 5.93 1,061 2,120,028
2022-05-24 2022-05-23 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 7,010 4,443,719 0.16 5.99 41,972 26,606,323
2022-05-24 2022-05-23 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 827 357,330 0.23 5.99 4,952 2,139,478
2022-05-24 2022-05-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 7,772 4,436,709 0.18 5.84 45,405 25,919,698
2022-05-24 2022-05-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 946 356,503 0.27 5.84 5,527 2,082,726
2022-05-24 2022-05-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 7,248 4,428,937 0.16 5.84 42,335 25,868,978
2022-05-24 2022-05-20 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 883 355,557 0.25 5.84 5,158 2,076,773
2022-05-18 2022-05-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,489 15,142,074 0.05 5.97 44,701 90,381,525
2022-05-18 2022-05-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 912 1,245,661 0.07 5.97 5,444 7,435,226
2022-05-18 2022-05-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 182,827 15,134,585 1.22 5.97 1,091,221 90,332,284
2022-05-18 2022-05-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 22,266 1,244,749 1.82 5.97 132,897 7,429,409
2022-05-18 2022-05-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 9,157 14,951,758 0.06 5.95 54,518 89,018,282
2022-05-18 2022-05-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,115 1,222,483 0.09 5.95 6,638 7,278,297
2022-05-18 2022-05-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 90,674 14,942,601 0.61 5.99 542,929 89,471,812
2022-05-18 2022-05-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 11,043 1,221,368 0.91 5.99 66,122 7,313,185
2022-05-18 2022-05-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 8,118 14,851,927 0.05 5.99 48,599 88,912,546
2022-05-18 2022-05-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 989 1,210,325 0.08 5.99 5,921 7,245,732
2022-05-18 2022-05-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 15,154 14,843,809 0.10 5.75 87,098 85,314,792
2022-05-18 2022-05-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,846 1,209,336 0.15 5.75 10,610 6,950,659
2022-05-18 2022-05-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 93,690 14,828,655 0.64 5.71 534,979 84,673,103
2022-05-18 2022-05-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 11,410 1,207,490 0.95 5.71 65,152 6,894,889
2022-05-18 2022-05-18 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 30,003 4,421,689 0.68 6.00 180,018 26,530,134
2022-05-18 2022-05-18 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 3,654 354,674 1.04 6.00 21,924 2,128,044
2022-05-18 2022-05-18 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 692 4,391,686 0.02 5.92 4,095 25,989,998
2022-05-18 2022-05-18 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 84 351,020 0.02 5.92 497 2,077,336
2022-05-18 2022-05-17 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 16,501 4,390,994 0.38 6.13 101,153 26,917,232
2022-05-18 2022-05-17 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,010 350,936 0.58 6.13 12,322 2,151,273
2022-05-18 2022-05-16 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 16,937 4,374,493 0.39 5.83 98,673 25,485,359
2022-05-18 2022-05-16 4 TRDA Entrada Therapeutics, Inc.
Common Stock 		P - Purchase 2,063 348,926 0.59 5.83 12,019 2,032,808
2022-05-17 2022-05-13 4 SGEN Seagen Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 3,676 3,676
2022-05-17 2022-05-13 4 SGEN Seagen Inc.
Common Stock 		A - Award 1,503 42,966,507 0.00
2022-05-17 2022-05-13 4 SGEN Seagen Inc.
Common Stock 		A - Award 1,503 42,966,507 0.00
2022-05-16 2022-05-12 4 NLTX Neoleukin Therapeutics, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 25,000 25,000
2022-05-12 2022-05-11 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 22,983 2,528,583 0.92 1.99 45,628 5,019,996
2022-05-12 2022-05-11 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 2,882 256,209 1.14 1.99 5,722 508,652
2022-05-12 2022-05-10 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 758,094 2,505,600 43.38 1.95 1,478,283 4,885,920
2022-05-12 2022-05-10 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 95,060 253,327 60.06 1.95 185,367 493,988
2022-05-12 2022-05-10 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 101,831 1,747,506 6.19 1.93 196,962 3,380,026
2022-05-12 2022-05-10 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 12,769 158,267 8.78 1.93 24,698 306,120
2022-05-12 2022-05-10 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 325,373 1,645,675 24.64 1.70 553,134 2,797,648
2022-05-12 2022-05-10 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 40,800 145,498 38.97 1.70 69,360 247,347
2022-04-05 2022-04-01 4 IGMS IGM Biosciences, Inc.
Non-Voting Common Stock 		P - Purchase 2,592,497 4,674,392 124.53 23.00 59,627,431 107,511,016
2022-04-05 2022-04-01 4 IGMS IGM Biosciences, Inc.
Non-Voting Common Stock 		P - Purchase 233,590 421,532 124.29 23.00 5,372,570 9,695,236
2022-04-04 2022-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 440 33,419,495 0.00
2022-04-04 2022-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 440 33,419,495 0.00
2022-03-15 2022-03-12 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 29,497 29,497
2022-03-10 2022-03-08 4 SGEN Seagen Inc.
Non-Qualified Stock Option (right to buy) 		M - Exercise -17,500 0 -100.00
2022-03-10 2022-03-08 4 SGEN Seagen Inc.
Non-Qualified Stock Option (right to buy) 		M - Exercise -17,500 0 -100.00
2022-03-10 2022-03-08 4 SGEN Seagen Inc.
Common Stock 		M - Exercise 17,500 42,965,004 0.04 20.06 351,050 861,877,980
2022-03-10 2022-03-08 4 SGEN Seagen Inc.
Common Stock 		M - Exercise 17,500 42,965,004 0.04 20.06 351,050 861,877,980
2022-03-10 2022-03-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 175,795 33,419,055 0.53 73.31 12,887,303 2,449,907,477
2022-03-10 2022-03-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 14,490 2,941,147 0.50 73.31 1,062,243 215,611,663
2022-03-10 2022-03-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1,017 33,243,260 0.00 71.95 73,177 2,391,975,557
2022-03-10 2022-03-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 84 2,926,657 0.00 71.95 6,044 210,583,800
2022-03-10 2022-03-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 25,107 33,242,243 0.08 71.90 1,805,126 2,390,027,518
2022-03-10 2022-03-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,070 2,926,573 0.07 71.90 148,827 210,412,697
2022-03-10 2022-03-09 4 INCY INCYTE CORP
Common Stock 		P - Purchase 65,147 33,217,136 0.20 71.72 4,672,408 2,382,366,211
2022-03-10 2022-03-09 4 INCY INCYTE CORP
Common Stock 		P - Purchase 5,370 2,924,503 0.18 71.72 385,142 209,748,280
2022-03-10 2022-03-08 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2022-03-10 2022-03-08 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2022-03-10 2022-03-08 4 INCY INCYTE CORP
Common Stock 		P - Purchase 92,385 33,151,989 0.28 70.68 6,529,310 2,343,016,823
2022-03-10 2022-03-08 4 INCY INCYTE CORP
Common Stock 		P - Purchase 7,615 2,919,133 0.26 70.68 538,190 206,309,725
2022-03-10 2022-03-08 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 33,059,604 0.06 22.05 441,000 728,964,268
2022-03-10 2022-03-08 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 33,059,604 0.06 22.05 441,000 728,964,268
2022-02-22 2022-02-22 4 INCY INCYTE CORP
Common Stock 		P - Purchase 92,234 33,039,604 0.28 68.07 6,278,507 2,249,055,404
2022-02-22 2022-02-22 4 INCY INCYTE CORP
Common Stock 		P - Purchase 7,566 2,891,518 0.26 68.07 515,029 196,829,968
2022-02-22 2022-02-18 4 INCY INCYTE CORP
Common Stock 		P - Purchase 22,178 32,947,370 0.07 68.43 1,517,656 2,254,611,592
2022-02-22 2022-02-18 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1,827 2,883,952 0.06 68.43 125,023 197,350,854
2022-02-22 2022-02-18 4 INCY INCYTE CORP
Common Stock 		P - Purchase 100,731 32,925,192 0.31 68.37 6,886,696 2,251,003,187
2022-02-22 2022-02-18 4 INCY INCYTE CORP
Common Stock 		P - Purchase 8,296 2,882,125 0.29 68.37 567,174 197,042,816
2022-02-22 2022-02-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 285,672 32,824,461 0.88 67.74 19,352,821 2,223,689,828
2022-02-22 2022-02-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 7,300 32,538,789 0.02 67.40 491,984 2,192,951,685
2022-02-17 2022-02-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 271,997 14,734,965 1.88 54.57 14,843,883 804,141,559
2022-02-17 2022-02-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 22,403 1,196,080 1.91 54.57 1,222,615 65,274,511
2022-02-17 2022-02-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,174 14,462,968 0.04 53.82 278,457 778,376,690
2022-02-17 2022-02-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 426 1,173,677 0.04 53.82 22,927 63,165,653
2022-02-17 2022-02-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 64,119 14,457,794 0.45 54.26 3,479,200 784,503,035
2022-02-17 2022-02-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,281 1,173,251 0.45 54.26 286,556 63,662,476
2022-02-17 2022-02-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 23,804 14,393,675 0.17 53.73 1,279,048 773,408,142
2022-02-17 2022-02-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,961 1,167,970 0.17 53.73 105,369 62,757,948
2022-02-17 2022-02-15 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,359 14,369,871 0.04 54.16 290,217 778,200,364
2022-02-17 2022-02-15 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 441 1,166,009 0.04 54.16 23,882 63,145,217
2022-02-14 2022-02-14 4 INCY INCYTE CORP
Common Stock 		P - Purchase 182,326 32,531,489 0.56 66.04 12,040,390 2,148,304,711
2022-02-14 2022-02-14 4 INCY INCYTE CORP
Common Stock 		P - Purchase 320,526 32,349,163 1.00 66.02 21,159,973 2,135,575,284
2022-02-14 2022-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 10,985 32,028,637 0.03 66.95 735,433 2,144,278,813
2022-02-14 2022-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 265,522 32,017,652 0.84 66.81 17,740,295 2,139,192,181
2022-02-14 2022-02-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 772,751 31,752,130 2.49 67.54 52,192,839 2,144,589,664
2022-02-14 2022-02-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 6,100 30,979,379 0.02 67.20 409,899 2,081,705,841
2022-02-14 2022-02-10 4 INCY INCYTE CORP
Common Stock 		P - Purchase 40,164 30,973,279 0.13 66.57 2,673,577 2,061,782,777
2022-01-31 2022-01-31 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 27,841 14,364,512 0.19 57.22 1,593,076 821,944,559
2022-01-31 2022-01-31 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,307 1,165,568 0.20 57.22 132,008 66,694,384
2022-01-31 2022-01-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 11,526 14,336,671 0.08 51.61 594,898 739,967,202
2022-01-31 2022-01-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 953 1,163,261 0.08 51.61 49,188 60,040,088
2022-01-31 2022-01-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 17,119 14,325,145 0.12 50.56 865,460 724,214,868
2022-01-31 2022-01-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,414 1,162,308 0.12 50.56 71,485 58,761,062
2022-01-31 2022-01-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 22,395 14,308,026 0.16 49.70 1,113,056 711,124,631
2022-01-31 2022-01-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,851 1,160,894 0.16 49.70 91,997 57,697,709
2022-01-31 2022-01-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 54,024 14,285,631 0.38 51.67 2,791,490 738,157,125
2022-01-31 2022-01-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,465 1,159,043 0.39 51.67 230,712 59,889,259
2022-01-31 2022-01-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 117,291 14,231,607 0.83 51.59 6,050,820 734,181,565
2022-01-31 2022-01-27 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 86,479 14,114,316 0.62 52.04 4,500,497 734,530,176
2022-01-25 2022-01-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,500 14,027,837 0.04 58.90 323,934 826,198,919
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 57,547 14,022,337 0.41 58.87 3,387,844 825,507,599
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 9,350 13,964,790 0.07 58.76 549,368 820,513,805
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 132,367 13,955,440 0.96 58.13 7,693,938 811,171,114
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 25,900 13,823,073 0.19 57.59 1,491,519 796,037,599
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 116,083 13,797,173 0.85 56.86 6,601,060 784,576,243
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,200 13,681,090 0.01 56.60 67,914 774,281,289
2022-01-25 2022-01-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 19,750 13,679,890 0.14 56.39 1,113,649 771,372,061
2022-01-25 2022-01-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 31,207 13,660,140 0.23 57.53 1,795,292 785,847,364
2022-01-25 2022-01-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 102,207 13,628,933 0.76 56.57 5,782,279 771,045,981
2022-01-04 2021-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 419 30,933,115 0.00
2022-01-04 2021-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 419 30,933,115 0.00
2021-12-17 2021-12-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 193,997 30,932,696 0.63 72.91 14,144,224 2,255,287,399
2021-12-17 2021-12-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 881,875 30,738,699 2.95 72.77 64,177,924 2,236,990,377
2021-12-17 2021-12-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 29,703 29,856,824 0.10 72.00 2,138,616 2,149,691,328
2021-12-17 2021-12-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 139,612 29,827,121 0.47 71.96 10,045,795 2,146,213,474
2021-12-17 2021-12-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 288,368 29,687,509 0.98 71.91 20,736,197 2,134,793,147
2021-12-17 2021-12-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 5,382 29,399,141 0.02 71.03 382,302 2,088,323,882
2021-12-17 2021-12-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 9,893 29,393,759 0.03 70.24 694,840 2,064,485,360
2021-12-17 2021-12-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 36,476 29,383,866 0.12 69.63 2,539,700 2,045,898,684
2021-12-17 2021-12-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 9,352 29,347,390 0.03 68.52 640,841 2,011,015,226
2021-12-17 2021-12-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 861 29,338,038 0.00 67.90 58,460 1,991,999,972
2021-12-16 3 TRDA Entrada Therapeutics, Inc.
Common Stock 		346,863
2021-12-16 3 TRDA Entrada Therapeutics, Inc.
Common Stock 		4,357,556
2021-12-02 2021-12-01 4 SGEN Seagen Inc.
Common Stock 		S - Sale -51,399 42,947,504 -0.12 161.39 -8,295,146 6,931,181,712
2021-12-02 2021-12-01 4 SGEN Seagen Inc.
Common Stock 		S - Sale -4,738 4,069,762 -0.12 161.39 -764,653 656,807,901
2021-12-02 2021-12-01 4 SGEN Seagen Inc.
Common Stock 		S - Sale -8,332 42,998,903 -0.02 161.34 -1,344,327 6,937,658,005
2021-12-02 2021-12-01 4 SGEN Seagen Inc.
Common Stock 		S - Sale -768 4,074,500 -0.02 161.34 -123,913 657,400,202
2021-12-02 2021-12-01 4 SGEN Seagen Inc.
Common Stock 		S - Sale -25,833 43,007,235 -0.06 160.80 -4,154,029 6,915,701,011
2021-12-02 2021-12-01 4 SGEN Seagen Inc.
Common Stock 		S - Sale -2,381 4,075,268 -0.06 160.80 -382,872 655,316,135
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -1,007 43,033,068 0.00 165.68 -166,844 7,129,895,142
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -93 4,077,649 0.00 165.68 -15,409 675,601,605
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -9,618 43,034,075 -0.02 164.82 -1,585,266 7,092,996,737
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -886 4,077,742 -0.02 164.82 -146,033 672,104,854
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -1,337 43,043,693 0.00 163.39 -218,449 7,032,809,999
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -123 4,078,628 0.00 163.39 -20,097 666,397,648
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -20,154 43,045,030 -0.05 160.96 -3,243,986 6,928,523,724
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -1,858 4,078,751 -0.05 160.96 -299,063 656,515,353
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -29,432 43,065,184 -0.07 160.53 -4,724,631 6,913,124,792
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -2,713 4,080,609 -0.07 160.53 -435,510 655,047,921
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -5,860 43,094,616 -0.01 160.08 -938,044 6,898,400,822
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -540 4,083,322 -0.01 160.08 -86,441 653,640,627
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -208,597 43,100,476 -0.48 160.00 -33,375,520 6,896,076,160
2021-12-02 2021-11-30 4 SGEN Seagen Inc.
Common Stock 		S - Sale -19,226 4,083,862 -0.47 160.00 -3,076,160 653,417,920
2021-11-19 2021-11-18 4 TLIS Talis Biomedical Corp
Common Stock 		P - Purchase 50,000 7,053,176 0.71 4.36 218,250 30,787,113
2021-10-04 2021-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 393 29,337,177 0.00
2021-10-04 2021-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 393 29,337,177 0.00
2021-10-01 2021-09-30 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 86,932 13,526,726 0.65 95.83 8,330,572 1,296,247,215
2021-10-01 2021-09-29 4 KOD Kodiak Sciences Inc.
Common Stock Warrant (right to buy) 		M - Exercise -138,815 0 -100.00
2021-10-01 2021-09-29 4 KOD Kodiak Sciences Inc.
Common Stock Warrant (right to buy) 		M - Exercise -11,184 0 -100.00
2021-10-01 2021-09-29 4 KOD Kodiak Sciences Inc.
Common Stock 		F - Taxes -14 13,439,794 0.00 102.00 -1,428 1,370,858,988
2021-10-01 2021-09-29 4 KOD Kodiak Sciences Inc.
Common Stock 		M - Exercise 138,815 13,439,808 1.04 0.01 1,388 134,398
2021-10-01 2021-09-29 4 KOD Kodiak Sciences Inc.
Common Stock 		F - Taxes -2 1,154,578 0.00 102.00 -204 117,766,956
2021-10-01 2021-09-29 4 KOD Kodiak Sciences Inc.
Common Stock 		M - Exercise 11,184 1,154,580 0.98 0.01 112 11,546
2021-09-17 2021-09-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,153 13,300,993 0.01 94.59 109,064 1,258,164,870
2021-09-17 2021-09-15 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 400 13,299,840 0.00 94.48 37,791 1,256,535,634
2021-09-17 2021-09-15 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 30,285 13,299,440 0.23 94.38 2,858,425 1,255,257,005
2021-09-09 2021-09-07 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 52,201 13,269,155 0.39 93.35 4,872,948 1,238,671,639
2021-09-09 2021-09-07 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,300 13,216,954 0.04 92.88 492,279 1,227,629,017
2021-08-19 2021-08-19 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 73,635 13,211,654 0.56 87.61 6,451,464 1,157,527,175
2021-08-19 2021-08-19 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,396 13,138,019 0.02 87.48 209,607 1,149,341,492
2021-08-19 2021-08-19 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,649 13,135,623 0.04 87.07 404,793 1,143,731,830
2021-08-19 2021-08-19 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,968 13,130,974 0.02 86.94 258,033 1,141,587,183
2021-08-19 2021-08-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 400 13,128,006 0.00 89.66 35,863 1,177,008,444
2021-08-19 2021-08-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,100 13,127,606 0.01 88.16 96,982 1,157,395,383
2021-08-19 2021-08-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 8,186 13,126,506 0.06 87.91 719,659 1,153,995,773
2021-08-19 2021-08-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 12,898 13,118,320 0.10 87.79 1,132,303 1,151,644,194
2021-08-19 2021-08-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,764 13,105,422 0.06 85.95 667,333 1,126,439,853
2021-08-19 2021-08-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 400 13,097,658 0.00 84.80 33,921 1,110,714,143
2021-08-13 2021-08-13 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 400 13,097,258 0.00 88.82 35,526 1,163,232,969
2021-08-13 2021-08-13 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 16,269 13,096,858 0.12 88.76 1,444,017 1,162,461,400
2021-08-13 2021-08-13 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 21,595 13,080,589 0.17 88.59 1,913,036 1,158,770,138
2021-08-13 2021-08-12 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,086 13,058,994 0.05 88.01 535,634 1,149,333,815
2021-08-13 2021-08-12 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,600 13,052,908 0.04 86.44 397,646 1,128,354,716
2021-08-13 2021-08-12 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 300 13,048,308 0.00 85.58 25,674 1,116,674,199
2021-08-13 2021-08-11 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,500 13,048,008 0.03 88.00 395,990 1,148,195,998
2021-08-13 2021-08-11 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 44,700 13,043,508 0.34 86.07 3,847,481 1,122,699,081
2021-08-13 2021-08-11 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 600 12,998,808 0.00 85.72 51,434 1,114,295,518
2021-08-13 2021-08-11 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,723 12,998,208 0.03 84.39 314,185 1,096,922,673
2021-07-22 2021-07-20 4 TCRX TScan Therapeutics, Inc.
Non-Voting Common Stock 		C - Conversion 3,960,811 3,960,811
2021-07-22 2021-07-20 4 TCRX TScan Therapeutics, Inc.
Series C Convertible Preferred Stock 		C - Conversion -3,960,811 0 -100.00
2021-07-22 2021-07-20 4 TCRX TScan Therapeutics, Inc.
Non-Voting Common Stock 		C - Conversion 315,777 315,777
2021-07-22 2021-07-20 4 TCRX TScan Therapeutics, Inc.
Series C Convertible Preferred Stock 		C - Conversion -315,777 0 -100.00
2021-07-22 2021-07-20 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 1,320,302 1,320,302 15.00 19,804,530 19,804,530
2021-07-22 2021-07-20 4 TCRX TScan Therapeutics, Inc.
Common Stock 		P - Purchase 104,698 104,698 15.00 1,570,470 1,570,470
2021-07-02 2021-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 345 29,336,784 0.00
2021-07-02 2021-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 345 29,336,784 0.00
2021-07-01 2021-06-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Non-Qualified Share Option (right to buy) 		A - Award 66,474 66,474
2021-06-30 2021-06-30 4 KOD Kodiak Sciences Inc.
Non-Qualified Stock Options (right to buy) 		A - Award 7,368 7,368
2021-06-30 2021-06-30 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 121,612 12,994,485 0.94 92.75 11,279,014 1,205,185,206
2021-06-30 2021-06-30 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,009 12,872,873 0.05 91.64 642,276 1,179,617,303
2021-06-30 2021-06-30 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 22,353 12,865,864 0.17 90.20 2,016,332 1,160,553,683
2021-06-30 2021-06-30 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,603 12,843,511 0.04 89.74 413,070 1,152,566,402
2021-06-30 2021-06-29 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 30,221 12,838,908 0.24 90.70 2,741,157 1,164,536,460
2021-06-30 2021-06-29 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,200 12,808,687 0.01 90.40 108,474 1,157,841,261
2021-06-30 2021-06-29 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 11,731 12,807,487 0.09 90.39 1,060,378 1,157,682,838
2021-06-30 2021-06-29 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,847 12,795,756 0.03 89.90 345,828 1,150,282,163
2021-06-30 2021-06-29 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,079 12,791,909 0.06 89.87 636,196 1,149,620,375
2021-06-30 2021-06-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,459 12,784,830 0.08 91.87 960,845 1,174,514,205
2021-06-30 2021-06-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 22,445 12,774,371 0.18 91.80 2,060,393 1,172,654,044
2021-06-30 2021-06-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,170 12,751,926 0.08 90.76 923,046 1,157,386,482
2021-06-30 2021-06-28 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,200 12,741,756 0.04 90.27 469,420 1,150,237,814
2021-06-24 2021-06-22 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Options (right to buy) 		A - Award 23,274 23,274
2021-06-24 2021-06-22 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 12,782 38,452,877 0.03
2021-06-24 2021-06-22 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 12,782 38,452,877 0.03
2021-06-22 2021-06-18 4 PRLD Prelude Therapeutics Inc
Non-Qualified Stock Options (right to buy) 		A - Award 23,344 23,344
2021-06-21 2021-06-16 4 BGNE BeiGene, Ltd.
Share Option (Right to Buy) 		A - Award 34,996 34,996
2021-06-21 2021-06-16 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 15,600 34,189 83.92
2021-06-21 2021-06-16 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 15,600 34,189 83.92
2021-06-10 2021-06-08 4 AGLE Aeglea BioTherapeutics, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 40,000 40,000
2021-05-28 2021-05-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 8,010 8,010
2021-05-28 2021-05-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,923 29,336,439 0.01
2021-05-28 2021-05-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,923 29,336,439 0.01
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 3,462 3,462
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Non-Qualified Stock Option (right to buy) 		M - Exercise -17,500 0 -100.00
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Non-Qualified Stock Option (right to buy) 		M - Exercise -17,500 0 -100.00
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Common Stock 		A - Award 1,402 43,309,073 0.00
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Common Stock 		A - Award 1,402 43,309,073 0.00
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Common Stock 		M - Exercise 17,500 43,307,671 0.04 19.02 332,850 823,711,902
2021-05-18 2021-05-14 4 SGEN Seagen Inc.
Common Stock 		M - Exercise 17,500 43,307,671 0.04 19.02 332,850 823,711,902
2021-05-18 2021-05-14 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2021-05-18 2021-05-14 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2021-05-18 2021-05-14 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 29,334,516 0.07 18.97 379,400 556,475,769
2021-05-18 2021-05-14 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 2,870,749 0.70 18.97 379,400 54,458,109
2021-05-13 2021-05-11 4 NLTX Neoleukin Therapeutics, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 25,000 25,000
2021-04-01 2021-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 364 29,314,516 0.00
2021-04-01 2021-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 364 29,314,516 0.00
2021-02-25 2021-02-23 4 AGLE Aeglea BioTherapeutics, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 47,200 47,200
2021-02-25 3 AGLE Aeglea BioTherapeutics, Inc.
Common Stock 		315,516
2021-02-25 3 AGLE Aeglea BioTherapeutics, Inc.
Common Stock 		3,094,590
2021-02-23 2021-02-19 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 6,423 6,423
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 6,427,576 27,511,741 30.49
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 536,438 2,345,481 29.65
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 7,286,794 21,084,165 52.81
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 536,414 1,809,043 42.15
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 1,941 5,420 55.79
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 6,654,603 13,797,371 93.17
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 598,860 1,272,629 88.88
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 7,142,768 7,142,768
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 673,769 673,769
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series 1 Convertible Preferred Stock 		M - Exercise 3,479 3,479
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series F-2 Convertible Preferred Stock 		M - Exercise -9,191,433 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series F-2 Convertible Preferred Stock 		M - Exercise -767,106 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series E-2 Convertible Preferred Stock 		M - Exercise -10,420,117 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series E-2 Convertible Preferred Stock 		M - Exercise -767,072 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series E-1 Convertible Preferred Stock 		M - Exercise -2,776 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series D-2 Convertible Preferred Stock 		M - Exercise -9,516,082 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series D-2 Convertible Preferred Stock 		M - Exercise -856,370 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series C-1 Convertible Preferred Stock 		M - Exercise -10,214,159 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series C-1 Convertible Preferred Stock 		M - Exercise -963,490 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Series C-1 Convertible Preferred Stock 		M - Exercise -4,975 0 -100.00
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Common Stock 		P - Purchase 5,792,538 7,003,176 478.47 16.00 92,680,608 112,050,816
2021-02-19 2021-02-17 4 TLIS Talis Biomedical Corp
Common Stock 		P - Purchase 457,462 571,659 400.59 16.00 7,319,392 9,146,544
2021-02-19 2020-11-02 4 TLIS Talis Biomedical Corp
Series F-2 Convertible Preferred Stock 		A - Award 9,191,433 9,191,433 8.55 78,586,752 78,586,752
2021-02-19 2020-11-02 4 TLIS Talis Biomedical Corp
Series F-2 Convertible Preferred Stock 		A - Award 767,106 767,106 8.55 6,558,756 6,558,756
2021-02-16 2020-10-13 5 SGEN Seagen Inc.
Common Stock 		G - Gift -158,456 23,277 -87.19
2021-02-16 2020-10-13 5 SGEN Seagen Inc.
Common Stock 		G - Gift -158,460 23,280 -87.19
2021-02-11 3 TLIS Talis Biomedical Corp
Common Stock 		590
2021-02-11 3 TLIS Talis Biomedical Corp
Common Stock 		114,197
2021-02-11 3 TLIS Talis Biomedical Corp
Common Stock 		1,210,638
2021-01-29 2021-01-27 4 PRLD Prelude Therapeutics Inc
Non-Qualified Stock Options (right to buy) 		M - Exercise -5,188 41,500 -11.11
2021-01-29 2021-01-27 4 PRLD Prelude Therapeutics Inc
Non-Qualified Stock Options (right to buy) 		M - Exercise -5,188 41,500 -11.11
2021-01-29 2021-01-27 4 PRLD Prelude Therapeutics Inc
Common Stock 		M - Exercise 5,188 9,252,951 0.06 12.85 66,666 118,900,420
2021-01-29 2021-01-27 4 PRLD Prelude Therapeutics Inc
Common Stock 		M - Exercise 5,188 9,252,951 0.06 12.85 66,666 118,900,420
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Options (right to buy) 		M - Exercise -5,833 2,527 -69.77
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Options (right to buy) 		M - Exercise -5,833 2,527 -69.77
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Options (right to buy) 		M - Exercise -5,377 6,723 -44.44
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Options (right to buy) 		M - Exercise -5,377 6,723 -44.44
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		M - Exercise 5,833 2,895,306 0.20 40.27 234,895 116,593,973
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		M - Exercise 5,833 2,895,306 0.20 40.27 234,895 116,593,973
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		M - Exercise 5,377 2,889,473 0.19 16.00 86,032 46,231,568
2021-01-29 2021-01-27 4 IGMS IGM Biosciences, Inc.
Common Stock 		M - Exercise 5,377 2,889,473 0.19 16.00 86,032 46,231,568
2021-01-13 2021-01-11 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		P - Purchase 154,222 5,212,371 3.05 60.00 9,253,320 312,742,260
2021-01-13 2021-01-11 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		P - Purchase 12,444 509,480 2.50 60.00 746,640 30,568,800
2021-01-11 3 DBVT DBV Technologies S.A.
Ordinary Shares 		332,622
2021-01-11 3 DBVT DBV Technologies S.A.
Ordinary Shares 		3,953,416
2021-01-11 3 DBVT DBV Technologies S.A.
American Depositary Shares 		1,200,369
2021-01-11 3 DBVT DBV Technologies S.A.
American Depositary Shares 		13,413,895
2021-01-06 2021-01-04 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -111,094 10,699,954 -1.03 220.50 -24,496,227 2,359,339,857
2021-01-06 2021-01-04 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -10,060 968,943 -1.03 220.50 -2,218,230 213,651,932
2021-01-05 2020-12-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,884,096 0.01
2021-01-05 2020-12-31 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,884,096 0.01
2021-01-05 2020-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 343 29,314,152 0.00
2021-01-05 2020-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 343 29,314,152 0.00
2020-12-23 2020-07-07 4 NLTX Neoleukin Therapeutics, Inc.
Pre-Funded Warrants 		P - Purchase 518,555 10,283,888 5.31
2020-12-23 2020-07-07 4 NLTX Neoleukin Therapeutics, Inc.
Pre-Funded Warrants 		P - Purchase 38,974 1,199,122 3.36
2020-12-23 2020-07-07 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 394,360 3,501,691 12.69 15.25 6,013,990 53,400,788
2020-12-23 2020-07-07 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 29,640 320,049 10.21 15.25 452,010 4,880,747
2020-12-11 2020-12-11 4 IGMS IGM Biosciences, Inc.
Pre-funded Warrants 		P - Purchase 616,846 616,846 89.99 55,509,972 55,509,972
2020-12-11 2020-12-11 4 IGMS IGM Biosciences, Inc.
Pre-funded Warrants 		P - Purchase 49,820 49,820 89.99 4,483,302 4,483,302
2020-12-04 2020-12-04 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -1,386,033 10,811,048 -11.36 220.50 -305,620,276 2,383,836,084
2020-12-04 2020-12-04 4 BGNE BeiGene, Ltd.
American Depositary Shares 		S - Sale -125,513 979,003 -11.36 220.50 -27,675,616 215,870,162
2020-12-04 2020-10-13 4 BGNE BeiGene, Ltd.
American Depositary Shares 		G - Gift -13,516 10,418 -56.47
2020-12-04 2020-10-13 4 BGNE BeiGene, Ltd.
American Depositary Shares 		G - Gift -13,516 10,418 -56.47
2020-11-24 2020-11-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,411,619 12,736,556 12.46 108.00 152,454,852 1,375,548,048
2020-11-24 2020-11-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 116,158 1,143,396 11.31 108.00 12,545,064 123,486,768
2020-10-05 2020-10-01 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,883,873 0.01
2020-10-05 2020-10-01 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,883,873 0.01
2020-10-02 2020-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 317 29,313,809 0.00
2020-10-02 2020-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 317 29,313,809 0.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		C - Conversion 382,884 5,058,149 8.19
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series C Convertible Preferred Stock 		C - Conversion -382,884 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		C - Conversion 30,349 497,036 6.50
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series C Convertible Preferred Stock 		C - Conversion -30,349 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series C Convertible Preferred Stock 		C - Conversion -574,327 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series C Convertible Preferred Stock 		C - Conversion -45,524 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		C - Conversion 2,698,424 4,675,265 136.50
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series B Convertible Preferred Stock 		C - Conversion -2,698,424 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		C - Conversion 247,034 466,687 112.47
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series B Convertible Preferred Stock 		C - Conversion -247,034 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series B Convertible Preferred Stock 		C - Conversion -4,047,634 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series B Convertible Preferred Stock 		C - Conversion -370,552 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		C - Conversion 1,976,841 1,976,841
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series A Convertible Preferred Stock 		C - Conversion -1,976,841 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Non-Voting Common Stock 		C - Conversion 219,653 219,653
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series A Convertible Preferred Stock 		C - Conversion -219,653 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series A Convertible Preferred Stock 		C - Conversion -2,965,263 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Series A Convertible Preferred Stock 		C - Conversion -329,478 0 -100.00
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		P - Purchase 1,474,319 9,247,763 18.97 19.00 28,012,061 175,707,497
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		P - Purchase 104,628 870,873 13.65 19.00 1,987,932 16,546,587
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		C - Conversion 574,327 7,773,444 7.98
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		C - Conversion 45,524 766,245 6.32
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		C - Conversion 4,047,634 7,199,117 128.44
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		C - Conversion 370,552 720,721 105.82
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		C - Conversion 2,965,263 3,151,483 1,592.34
2020-09-30 2020-09-29 4 PRLD Prelude Therapeutics Inc
Common Stock 		C - Conversion 329,478 350,169 1,592.37
2020-09-30 2020-09-24 4 PRLD Prelude Therapeutics Inc
Non-Qualified Stock Option (right to buy) 		A - Award 46,688 46,688
2020-09-30 2020-08-21 4 PRLD Prelude Therapeutics Inc
Series C Preferred Stock 		P - Purchase 957,211 957,211 14.52 13,898,321 13,898,321
2020-09-30 2020-08-21 4 PRLD Prelude Therapeutics Inc
Series C Preferred Stock 		P - Purchase 75,873 75,873 14.52 1,101,646 1,101,646
2020-09-30 2020-03-27 4 PRLD Prelude Therapeutics Inc
Series B Preferred Stock 		P - Purchase 3,373,029 3,373,029 3.93 13,264,099 13,264,099
2020-09-30 2020-03-27 4 PRLD Prelude Therapeutics Inc
Series B Preferred Stock 		P - Purchase 308,793 308,793 3.93 1,214,298 1,214,298
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,843 11,324,937 0.07 58.09 455,565 657,814,628
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 557 1,027,238 0.05 58.09 32,354 59,667,633
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 19,235 11,317,094 0.17 56.92 1,094,854 644,167,859
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,365 1,026,681 0.13 56.92 77,696 58,438,580
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,705 11,297,859 0.04 56.76 267,055 641,265,347
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 334 1,025,316 0.03 56.76 18,958 58,196,834
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 13,153 11,293,154 0.12 55.35 728,057 625,108,824
2020-09-25 2020-09-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 933 1,024,982 0.09 55.35 51,644 56,735,726
2020-09-24 2020-09-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 29,327 11,280,001 0.26 52.11 1,528,374 587,856,124
2020-09-24 2020-09-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,081 1,024,049 0.20 52.11 108,451 53,368,211
2020-09-24 2020-09-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 4,306 11,250,674 0.04 51.41 221,368 578,388,150
2020-09-24 2020-09-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 306 1,021,968 0.03 51.41 15,731 52,538,557
2020-09-24 2020-09-23 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 74,381 11,246,368 0.67 52.44 3,900,235 589,713,428
2020-09-24 2020-09-23 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,278 1,021,662 0.52 52.44 276,757 53,571,766
2020-09-24 2020-09-23 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,467 11,171,987 0.09 52.40 548,468 585,408,767
2020-09-24 2020-09-23 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 743 1,016,384 0.07 52.40 38,933 53,258,217
2020-09-24 2020-09-23 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,120 11,161,520 0.01 51.97 58,206 580,064,194
2020-09-24 2020-09-23 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 80 1,015,641 0.01 51.97 4,158 52,782,863
2020-09-24 2020-09-22 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 22,361 11,160,400 0.20 51.98 1,162,235 580,072,950
2020-09-24 2020-09-22 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,587 1,015,561 0.16 51.98 82,486 52,784,799
2020-09-24 2020-09-22 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 36,647 11,138,039 0.33 50.15 1,837,909 558,591,591
2020-09-24 2020-09-22 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,601 1,013,974 0.26 50.15 130,445 50,852,520
2020-09-24 2020-09-22 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,983 11,101,392 0.10 49.72 546,102 551,988,964
2020-09-24 2020-09-22 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 779 1,011,373 0.08 49.72 38,734 50,287,994
2020-09-24 3 PRLD Prelude Therapeutics Inc
Common Stock 		20,691
2020-09-24 3 PRLD Prelude Therapeutics Inc
Common Stock 		186,220
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 15,172 11,090,409 0.14 47.47 720,200 526,450,625
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,220 1,010,594 0.12 47.47 57,912 47,971,887
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 76,473 11,075,237 0.70 47.39 3,623,857 524,826,686
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,151 1,009,374 0.61 47.39 291,480 47,831,609
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 15,807 10,998,764 0.14 47.04 743,482 517,326,865
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,272 1,003,223 0.13 47.04 59,829 47,186,594
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 185 10,982,957 0.00 45.88 8,487 503,843,152
2020-09-08 2020-09-08 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 15 1,001,951 0.00 45.88 688 45,964,502
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 9,101 10,982,772 0.08 47.50 432,281 521,661,901
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 712 1,001,936 0.07 47.50 33,819 47,590,157
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 26,238 10,973,671 0.24 47.26 1,239,984 518,605,815
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,054 1,001,224 0.21 47.26 97,070 47,316,945
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 29,319 10,947,433 0.27 46.62 1,366,767 510,337,579
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,295 999,170 0.23 46.62 106,986 46,578,408
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 12,132 10,918,114 0.11 45.30 549,535 494,550,167
2020-09-08 2020-09-04 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 950 996,875 0.10 45.30 43,031 45,154,749
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 32,088 10,905,982 0.30 49.00 1,572,312 534,393,118
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,512 995,925 0.25 49.00 123,088 48,800,325
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 77,456 10,873,894 0.72 47.60 3,686,658 517,562,558
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,062 993,413 0.61 47.60 288,532 47,283,280
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,987 10,796,438 0.03 47.45 141,725 512,260,753
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 234 987,351 0.02 47.45 11,103 46,847,040
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,359 10,793,451 0.02 46.97 110,798 506,947,886
2020-09-08 2020-09-03 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 185 987,117 0.02 46.97 8,689 46,363,010
2020-08-21 2020-08-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 83,832 10,791,092 0.78 49.08 4,114,734 529,660,248
2020-08-21 2020-08-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,645 986,932 0.68 49.08 326,157 48,441,682
2020-08-21 2020-08-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,286 10,707,260 0.02 48.74 111,430 521,922,177
2020-08-21 2020-08-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 181 980,287 0.02 48.74 8,823 47,783,796
2020-08-21 2020-08-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 42,714 10,704,974 0.40 47.74 2,039,256 511,077,939
2020-08-21 2020-08-21 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,386 980,106 0.35 47.74 161,655 46,792,319
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 754 10,662,260 0.01 47.82 36,058 509,896,995
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 60 976,720 0.01 47.82 2,869 46,709,290
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 41,155 10,661,506 0.39 47.72 1,963,970 508,780,926
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,262 976,660 0.34 47.72 155,667 46,607,485
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,640 10,620,351 0.10 46.50 494,716 493,802,778
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 843 973,398 0.09 46.50 39,196 45,259,016
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,576 10,609,711 0.03 46.30 165,575 491,248,717
2020-08-21 2020-08-20 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 283 972,555 0.03 46.30 13,103 45,031,047
2020-08-21 2020-08-19 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,585 10,606,135 0.03 46.99 168,447 498,345,162
2020-08-21 2020-08-19 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 284 972,272 0.03 46.99 13,344 45,683,658
2020-07-28 2020-07-24 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		A - Award 1,335,362 11,638,314 12.96 21.00 28,042,602 244,404,594
2020-07-28 2020-07-24 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		A - Award 93,210 1,143,650 8.87 21.00 1,957,410 24,016,650
2020-07-20 2020-07-20 4 BCEL Atreca, Inc.
Class B Common Stock 		P - Purchase 728,370 6,173,327 13.38 16.00 11,653,920 98,773,232
2020-07-20 2020-07-20 4 BCEL Atreca, Inc.
Class B Common Stock 		P - Purchase 52,880 542,114 10.81 16.00 846,080 8,673,824
2020-07-20 2020-07-20 4 BCEL Atreca, Inc.
Class B Common Stock 		P - Purchase 728,370 6,173,327 13.38 16.00 11,653,920 98,773,232
2020-07-20 2020-07-20 4 BCEL Atreca, Inc.
Class B Common Stock 		P - Purchase 52,880 542,114 10.81 16.00 846,080 8,673,824
2020-07-17 2020-07-15 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 13,589,904 18,840,379 258.83 14.23 193,395,206 268,113,665
2020-07-17 2020-07-15 4 BGNE BeiGene, Ltd.
Ordinary Shares 		A - Award 994,276 1,021,851 3,605.72 14.23 14,149,343 14,541,757
2020-07-06 2020-07-01 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,883,650 0.01
2020-07-06 2020-07-01 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,883,650 0.01
2020-07-02 2020-06-30 4 KOD Kodiak Sciences Inc.
Non-Qualified Stock Options (right to buy) 		A - Award 7,106 7,106
2020-07-02 2020-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 294 29,313,492 0.00
2020-07-02 2020-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 294 29,313,492 0.00
2020-07-02 2020-06-30 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Non-Qualified Share Option (right to buy) 		A - Award 37,520 37,520
2020-06-25 2020-06-23 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Options (right to buy) 		A - Award 11,158 11,158
2020-06-25 2020-06-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 6,118 38,440,095 0.02
2020-06-25 2020-06-23 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		A - Award 6,118 38,440,095 0.02
2020-06-19 2020-06-17 4 BGNE BeiGene, Ltd.
Share Option (Right to Buy) 		A - Award 90,766 90,766
2020-06-10 2020-06-08 4 KOD Kodiak Sciences Inc.
Non-Qualified Stock Options (right to buy) 		A - Award 4,135 4,135
2020-05-28 2020-05-28 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1 29,313,198 0.00 102.55 103 3,006,068,455
2020-05-28 2020-05-28 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1 29,313,198 0.00 102.55 103 3,006,068,455
2020-05-28 2020-05-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 10,514 10,514
2020-05-28 2020-05-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,282 29,313,197 0.00
2020-05-28 2020-05-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,282 29,313,197 0.00
2020-05-19 2020-05-15 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Option (right to buy) 		A - Award 3,171 3,171
2020-05-19 2020-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 1,335 43,290,171 0.00
2020-05-19 2020-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 1,335 43,290,171 0.00
2020-05-19 2020-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -1,602,312 43,288,836 -3.57 160.00 -256,369,920 6,926,213,760
2020-05-19 2020-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -147,688 4,082,851 -3.49 160.00 -23,630,080 653,256,160
2020-05-18 2020-05-18 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		A - Award 1,465,603 10,302,952 16.58 18.25 26,747,255 188,028,874
2020-05-18 2020-05-18 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		A - Award 134,397 1,050,440 14.67 18.25 2,452,745 19,170,530
2020-05-18 2020-05-14 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		A - Award 1,189 7,846,213 0.02
2020-05-18 2020-05-14 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		A - Award 1,189 7,846,213 0.02
2020-05-18 2020-05-14 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,468 7,845,024 0.04
2020-05-18 2020-05-14 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,468 7,845,024 0.04
2020-05-12 2020-05-08 4 ZYME Zymeworks Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 9,000 9,000
2020-05-08 2020-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -457,803 44,891,148 -1.01 158.50 -72,561,776 7,115,246,958
2020-05-08 2020-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -42,197 4,230,539 -0.99 158.50 -6,688,224 670,540,432
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -4,343 45,348,951 -0.01 166.15 -721,610 7,534,941,349
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -400 4,272,736 -0.01 166.15 -66,462 709,935,168
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -48,880 45,353,294 -0.11 164.96 -8,063,118 7,481,361,460
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -4,505 4,273,136 -0.11 164.96 -743,133 704,885,404
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -84,663 45,402,174 -0.19 164.19 -13,901,157 7,454,764,558
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -7,805 4,277,641 -0.18 164.19 -1,281,534 702,362,986
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -16,159 45,486,837 -0.04 163.41 -2,640,610 7,433,195,079
2020-05-08 2020-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -1,489 4,285,446 -0.03 163.41 -243,324 700,302,730
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -41,072 45,502,996 -0.09 166.62 -6,843,564 7,581,873,004
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -3,786 4,286,935 -0.09 166.62 -630,837 714,304,543
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -91,613 45,544,068 -0.20 165.70 -15,180,641 7,546,834,244
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -8,444 4,290,721 -0.20 165.70 -1,399,205 710,989,633
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -178,862 45,635,681 -0.39 164.60 -29,440,041 7,511,468,804
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -16,485 4,299,165 -0.38 164.60 -2,713,372 707,627,082
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -45,606 45,814,543 -0.10 164.06 -7,482,107 7,516,320,180
2020-05-08 2020-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		S - Sale -4,204 4,315,650 -0.10 164.06 -689,707 708,024,244
2020-05-07 2020-05-05 4 NLTX Neoleukin Therapeutics, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 25,000 25,000
2020-04-29 2020-04-28 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2020-04-29 2020-04-28 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2020-04-29 2020-04-28 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 29,311,915 0.07 13.34 266,800 391,020,946
2020-04-29 2020-04-28 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 29,311,915 0.07 13.34 266,800 391,020,946
2020-04-24 2020-04-23 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -17,500 0 -100.00
2020-04-24 2020-04-23 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -17,500 0 -100.00
2020-04-24 2020-04-23 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 17,500 45,860,149 0.04 12.76 223,300 585,175,501
2020-04-24 2020-04-23 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 17,500 45,860,149 0.04 12.76 223,300 585,175,501
2020-04-03 2020-04-01 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,883,427 0.01
2020-04-03 2020-04-01 4 IGMS IGM Biosciences, Inc.
Common Stock 		A - Award 223 2,883,427 0.01
2020-04-01 2020-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 392 29,291,915 0.00 73.23 28,706 2,145,046,935
2020-04-01 2020-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 392 29,291,915 0.00 73.23 28,706 2,145,046,935
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 42,473 38,433,977 0.11 34.47 1,463,896 1,324,684,668
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,837 3,470,609 0.11 34.47 132,248 119,619,745
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 33,464 38,391,504 0.09 33.63 1,125,465 1,291,186,902
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,023 3,466,772 0.09 33.63 101,670 116,594,823
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,201 38,358,040 0.01 32.85 72,302 1,260,053,942
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 199 3,463,749 0.01 32.85 6,537 113,783,462
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 46,225 38,355,839 0.12 32.61 1,507,268 1,250,676,513
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 4,175 3,463,550 0.12 32.61 136,135 112,936,668
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 275 38,309,614 0.00 31.94 8,782 1,223,417,523
2020-03-18 2020-03-18 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 25 3,459,375 0.00 31.94 798 110,475,141
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 93,006 38,309,339 0.24 33.86 3,149,406 1,297,246,161
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 8,402 3,459,350 0.24 33.86 284,512 117,141,893
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 24,223 38,216,333 0.06 32.32 782,873 1,235,128,953
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,188 3,450,948 0.06 32.32 70,715 111,532,569
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 29,624 38,192,110 0.08 32.19 953,620 1,229,434,575
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,676 3,448,760 0.08 32.19 86,143 111,018,343
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 7,612 38,162,486 0.02 31.83 242,290 1,214,711,929
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 688 3,446,084 0.02 31.83 21,899 109,688,854
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 43,212 38,154,874 0.11 31.74 1,371,359 1,210,867,819
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,903 3,445,396 0.11 31.74 123,864 109,341,709
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,913 38,111,662 0.01 31.00 121,285 1,181,290,020
2020-03-18 2020-03-17 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 353 3,441,493 0.01 31.00 10,941 106,670,796
2020-03-18 2020-03-16 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 631,281 38,107,749 1.68 31.51 19,893,937 1,200,912,359
2020-03-18 2020-03-16 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 57,022 3,441,140 1.68 31.51 1,796,968 108,442,710
2020-03-18 2020-03-16 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 5,503 37,476,468 0.01 31.19 171,613 1,168,714,898
2020-03-18 2020-03-16 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 497 3,384,118 0.01 31.19 15,499 105,534,735
2020-03-18 2020-03-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 9,172 10,602,550 0.09 38.38 352,019 406,922,688
2020-03-18 2020-03-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 828 971,988 0.09 38.38 31,778 37,304,608
2020-03-18 2020-03-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,237 10,593,378 0.06 37.75 235,433 399,876,714
2020-03-18 2020-03-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 563 971,160 0.06 37.75 21,252 36,659,153
2020-03-18 2020-03-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 17,058 10,587,141 0.16 36.69 625,914 388,477,141
2020-03-18 2020-03-18 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,542 970,597 0.16 36.69 56,581 35,614,407
2020-03-18 2020-03-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 9,172 10,570,083 0.09 38.98 357,570 412,074,686
2020-03-18 2020-03-17 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 828 969,055 0.09 38.98 32,280 37,778,609
2020-03-18 2020-03-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 95,934 10,560,911 0.92 39.97 3,834,588 422,131,230
2020-03-18 2020-03-16 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 8,666 968,227 0.90 39.97 346,390 38,701,098
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 14,731 7,841,556 0.19 83.14 1,224,797 651,979,900
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,331 994,296 0.13 83.14 110,665 82,669,945
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,321 7,826,825 0.02 82.92 109,537 648,995,633
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 119 992,965 0.01 82.92 9,867 82,336,062
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 15,928 7,825,504 0.20 82.13 1,308,149 642,700,035
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,439 992,846 0.15 82.13 118,183 81,541,350
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 25,640 7,809,576 0.33 81.79 2,097,003 638,717,107
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,314 991,407 0.23 81.79 189,254 81,083,609
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,203 7,783,936 0.05 81.47 342,438 634,193,850
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 380 989,093 0.04 81.47 30,960 80,586,055
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 12,815 7,779,733 0.16 81.09 1,039,177 630,863,995
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 1,158 988,713 0.12 81.09 93,903 80,175,429
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 3,298 7,766,918 0.04 80.91 266,845 628,431,432
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 298 987,555 0.03 80.91 24,112 79,904,359
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 10,285 7,763,620 0.13 79.87 821,429 620,054,709
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 929 987,257 0.09 79.87 74,196 78,848,959
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 26,022 7,753,335 0.34 79.72 2,074,362 618,062,527
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,351 986,328 0.24 79.72 187,412 78,625,827
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,888 7,727,313 0.04 79.29 228,980 612,673,148
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 261 983,977 0.03 79.29 20,694 78,016,289
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,191 7,724,425 0.05 79.16 331,760 611,467,028
2020-03-18 2020-03-18 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 379 983,716 0.04 79.16 30,002 77,871,155
2020-03-18 2020-03-17 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 565 7,720,234 0.01 78.66 44,443 607,273,606
2020-03-18 2020-03-17 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 51 983,337 0.01 78.66 4,012 77,349,288
2020-03-18 2020-03-17 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 65,505 7,719,669 0.86 76.67 5,022,445 591,887,865
2020-03-18 2020-03-17 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,917 983,286 0.61 76.67 453,672 75,391,192
2020-03-18 2020-03-17 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 27,866 7,654,164 0.37 76.10 2,120,480 582,448,202
2020-03-18 2020-03-17 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,517 977,369 0.26 76.10 191,533 74,373,480
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 62,129 7,626,298 0.82 79.76 4,955,720 608,311,660
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 5,612 974,852 0.58 79.76 447,641 77,759,070
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 133,042 7,564,169 1.79 79.14 10,529,170 598,641,194
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 12,017 969,240 1.26 79.14 951,046 76,707,301
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7,612 7,431,127 0.10 77.94 593,260 579,163,461
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 688 957,223 0.07 77.94 53,621 74,603,568
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 8,309 7,423,515 0.11 77.89 647,203 578,230,946
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 750 956,535 0.08 77.89 58,419 74,506,233
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 32,228 7,415,206 0.44 75.66 2,438,422 561,046,350
2020-03-18 2020-03-16 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,911 955,785 0.31 75.66 220,251 72,316,222
2020-03-16 2020-03-16 4 ZYME Zymeworks Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 18,000 18,000
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		1,876,724
2020-03-16 3 ZYME Zymeworks Inc.
Common Stock 		3,248,692
2020-02-26 2020-02-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 82,740 10,464,977 0.80 57.82 4,783,944 605,074,505
2020-02-26 2020-02-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,460 959,561 0.78 57.82 431,330 55,480,857
2020-02-26 2020-02-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 8,989 10,382,237 0.09 59.61 535,824 618,873,727
2020-02-26 2020-02-26 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 811 952,101 0.09 59.61 48,343 56,753,693
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 14,631 10,373,248 0.14 59.99 877,642 622,240,319
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,319 951,290 0.14 59.99 79,120 57,063,226
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 145,994 10,358,617 1.43 57.68 8,421,518 597,526,463
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 13,164 949,971 1.41 57.68 759,352 54,798,127
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 14,051 10,212,623 0.14 57.22 803,980 584,353,012
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,267 936,807 0.14 57.22 72,496 53,602,879
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 14,402 10,198,572 0.14 58.80 846,819 599,662,775
2020-02-26 2020-02-25 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,298 935,540 0.14 58.80 76,321 55,008,536
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 8,623 10,184,170 0.08 60.77 524,043 618,919,508
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 777 934,242 0.08 60.77 47,220 56,776,409
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 6,788 10,175,547 0.07 58.54 397,393 595,711,118
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 612 933,465 0.07 58.54 35,829 54,648,215
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 7,122 10,168,759 0.07 58.39 415,826 593,714,180
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 642 932,853 0.07 58.39 37,484 54,465,649
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 3,577 10,161,637 0.04 57.62 206,108 585,517,589
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 323 932,211 0.03 57.62 18,611 53,714,371
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 21,301 10,158,060 0.21 56.69 1,207,513 575,841,121
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,921 931,888 0.21 56.69 108,898 52,826,960
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 5,804 10,136,759 0.06 56.62 328,631 573,958,500
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 523 929,967 0.06 56.62 29,613 52,656,126
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 10,121 10,130,955 0.10 56.25 569,277 569,836,839
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 912 929,444 0.10 56.25 51,297 52,278,530
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 92 10,120,834 0.00 55.45 5,102 561,225,547
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 8 928,532 0.00 55.45 444 51,489,421
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,813 10,120,742 0.02 55.77 101,117 564,468,192
2020-02-26 2020-02-24 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 164 928,524 0.02 55.77 9,147 51,786,940
2020-02-07 2020-02-05 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 10,000 10,000
2020-01-03 2019-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 316 29,291,523 0.00 87.32 27,593 2,557,735,788
2020-01-03 2019-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 316 29,291,523 0.00 87.32 27,593 2,557,735,788
2019-12-20 2019-12-20 4 NLTX Neoleukin Therapeutics, Inc.
Pre-funded Warrants 		A - Award 9,765,333 9,765,333
2019-12-20 2019-12-20 4 NLTX Neoleukin Therapeutics, Inc.
Pre-funded Warrants 		A - Award 1,160,148 1,161,048 128,905.33
2019-12-20 2019-12-20 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		D - Sale to Issuer -9,765,333 3,107,331 -75.86
2019-12-20 2019-12-20 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		D - Sale to Issuer -1,160,148 290,409 -79.98
2019-12-20 2019-12-20 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 2,767,505 12,872,664 27.39 8.40 23,247,042 108,130,378
2019-12-20 2019-12-20 4 NLTX Neoleukin Therapeutics, Inc.
Common Stock 		P - Purchase 250,037 1,450,557 20.83 8.40 2,100,311 12,184,679
2019-12-06 2019-12-06 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 1,743,993 10,118,929 20.82 46.00 80,223,678 465,470,734
2019-12-06 2019-12-06 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 158,180 928,360 20.54 46.00 7,276,280 42,704,560
2019-10-15 2019-10-10 4 NLTX Neoleukin Therapeutics, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 22,000 22,000
2019-10-03 2019-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 370 7,642,042 0.00 67.28 24,894 514,156,586
2019-10-03 2019-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 370 7,642,042 0.00 67.28 24,894 514,156,586
2019-10-03 2019-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 370 1,217,279 0.03 67.28 24,894 81,898,531
2019-10-03 2019-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 370 244,595 0.15 67.28 24,894 16,456,352
2019-10-03 2019-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 370 160,223 0.23 67.28 24,894 10,779,803
2019-10-02 2019-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 364 29,291,207 0.00 74.23 27,020 2,174,286,296
2019-10-02 2019-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 364 29,291,207 0.00 74.23 27,020 2,174,286,296
2019-09-20 2019-09-20 4 IGMS IGM Biosciences, Inc.
Non-Voting Common Stock 		C - Conversion 2,081,895 2,081,895
2019-09-20 2019-09-20 4 IGMS IGM Biosciences, Inc.
Series C Convertible Preferred 		C - Conversion -2,081,895 0 -100.00
2019-09-20 2019-09-20 4 IGMS IGM Biosciences, Inc.
Non-Voting Common Stock 		C - Conversion 187,942 187,942
2019-09-20 2019-09-20 4 IGMS IGM Biosciences, Inc.
Series C Convertible Preferred 		C - Conversion -187,942 0 -100.00
2019-09-20 2019-09-20 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 2,883,204 2,883,204 16.00 46,131,264 46,131,264
2019-09-20 2019-09-20 4 IGMS IGM Biosciences, Inc.
Common Stock 		P - Purchase 260,796 260,796 16.00 4,172,736 4,172,736
2019-09-20 2019-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,494,025 37,470,965 4.15 40.00 59,761,000 1,498,838,600
2019-09-20 2019-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 68,475 3,383,621 2.07 40.00 2,739,000 135,344,840
2019-09-20 2019-09-19 4 KOD Kodiak Sciences Inc.
Common Stock Warrant (right to buy) 		X - Other -1 138,815 0.00
2019-09-20 2019-09-19 4 KOD Kodiak Sciences Inc.
Common Stock 		X - Other 1 8,374,936 0.00 0.01 0 83,749
2019-09-19 2019-09-17 4 IGMS IGM Biosciences, Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 12,100 12,100
2019-08-30 2019-08-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		G - Gift -95,289 0 -100.00
2019-08-30 2019-08-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		G - Gift -95,289 0 -100.00
2019-08-30 2019-08-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		J - Other 8,341 95,289 9.59
2019-08-30 2019-08-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		J - Other 8,340 95,289 9.59
2019-08-30 2019-08-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		J - Other -8,866 43,361 -16.98
2019-08-30 2019-08-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		J - Other -7,815 165,610 -4.51
2019-08-08 2019-08-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 50,436 10,105,159 0.50 3.15 159,020 31,860,556
2019-08-08 2019-08-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 4,564 1,200,520 0.38 3.15 14,390 3,785,120
2019-08-08 2019-08-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 209,382 10,054,723 2.13 3.02 633,255 30,409,504
2019-08-08 2019-08-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 18,943 1,195,956 1.61 3.02 57,291 3,617,049
2019-08-08 2019-08-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,869 9,845,341 0.06 2.96 17,358 29,118,581
2019-08-08 2019-08-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 531 1,177,013 0.05 2.96 1,570 3,481,134
2019-08-08 2019-08-06 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 65,568 9,839,472 0.67 2.85 186,666 28,011,993
2019-08-08 2019-08-06 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,932 1,176,482 0.51 2.85 16,888 3,349,327
2019-08-08 2019-08-06 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 9,445 9,773,904 0.10 2.83 26,756 27,687,515
2019-08-08 2019-08-06 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 855 1,170,550 0.07 2.83 2,422 3,315,934
2019-07-03 2019-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 424 7,641,672 0.01 58.86 24,957 449,788,814
2019-07-03 2019-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 424 7,641,672 0.01 58.86 24,957 449,788,814
2019-07-03 2019-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 424 1,390,806 0.03 58.86 24,957 81,862,841
2019-07-03 2019-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 424 418,122 0.10 58.86 24,957 24,610,661
2019-07-03 2019-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 424 333,750 0.13 58.86 24,957 19,644,525
2019-07-03 2019-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 424 226,124 0.19 58.86 24,957 13,309,659
2019-07-03 2019-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,964 4,290,995 0.07 2.61 7,736 11,199,497
2019-07-03 2019-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,964 4,290,995 0.07 2.61 7,736 11,199,497
2019-07-02 2019-06-28 4 INCY INCYTE CORP
Common Stock 		A - Award 310 29,290,843 0.00 84.96 26,338 2,488,550,021
2019-07-02 2019-06-28 4 INCY INCYTE CORP
Common Stock 		A - Award 310 29,290,843 0.00 84.96 26,338 2,488,550,021
2019-06-28 2019-06-26 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 30,000 30,000
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Class B common stock 		P - Purchase 1,904,850 5,444,957 53.81 17.00 32,382,450 92,564,269
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Class B common stock 		P - Purchase 95,150 489,234 24.14 17.00 1,617,550 8,316,978
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Class B common stock 		C - Conversion 3,540,107 3,540,107
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Series C2 Preferred Stock 		C - Conversion -3,540,107 0 -100.00
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Class B common stock 		C - Conversion 394,084 394,084
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Series C2 Preferred Stock 		C - Conversion -394,084 0 -100.00
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Series B Preferred Stock 		C - Conversion -920,361 0 -100.00
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Series B Preferred Stock 		C - Conversion -89,878 0 -100.00
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Series A Preferred Stock 		C - Conversion -2,302,669 0 -100.00
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Series A Preferred Stock 		C - Conversion -219,852 0 -100.00
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Class A common stock 		C - Conversion 3,223,030 3,223,030
2019-06-26 2019-06-24 4 BCEL Atreca, Inc.
Class A common stock 		C - Conversion 309,730 309,730
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		A - Award 13,166 13,166
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 1,910 7,641,248 0.03
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 1,910 7,641,248 0.03
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 1,910 1,390,382 0.14
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 1,910 417,698 0.46
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 1,910 333,326 0.58
2019-06-18 2019-06-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 1,910 225,700 0.85
2019-06-07 2019-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other 74,229 181,733 69.05
2019-06-07 2019-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other 74,229 181,733 69.05
2019-06-07 2019-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other -1,002,483 4,302,354 -18.90
2019-06-07 2019-06-06 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		J - Other 14,840 14,840
2019-06-07 2019-06-06 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		J - Other 14,840 14,840
2019-06-07 2019-06-06 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		J - Other -200,423 98,980 -66.94
2019-06-07 2019-06-06 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		J - Other 31,229 102,876 43.59
2019-06-07 2019-06-06 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		J - Other 31,229 102,876 43.59
2019-06-07 2019-06-06 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		J - Other -421,756 3,315,146 -11.29
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other 880 880
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other 880 880
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other 1,660 1,660
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other 1,660 1,660
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other 6,256 6,256
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other 6,256 6,256
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other -6,009 0 -100.00
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other -11,337 0 -100.00
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Warrants to purchase Common Stock 		J - Other -42,724 0 -100.00
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		J - Other 21,929 21,929
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		J - Other 21,929 21,929
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		J - Other -59,267 0 -100.00
2019-06-07 2019-06-06 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		J - Other -178,967 347,757 -33.98
2019-06-07 2019-06-06 4 BGNE BeiGene, Ltd.
Ordinary shares 		J - Other 43,109 43,109
2019-06-07 2019-06-06 4 BGNE BeiGene, Ltd.
Ordinary shares 		J - Other 43,109 43,109
2019-06-07 2019-06-06 4 BGNE BeiGene, Ltd.
Ordinary shares 		J - Other -582,200 18,591 -96.91
2019-06-07 2019-06-06 4 BGNE BeiGene, Ltd.
American Depositary Shares 		J - Other 13,516 20,618 190.31
2019-06-07 2019-06-06 4 BGNE BeiGene, Ltd.
American Depositary Shares 		J - Other 13,516 20,618 190.31
2019-06-07 2019-06-06 4 BGNE BeiGene, Ltd.
American Depositary Shares 		J - Other -182,539 1,028,034 -15.08
2019-06-07 2019-06-05 4 BGNE BeiGene, Ltd.
Shares Option (Right to Buy) 		A - Award 129,220 129,220
2019-06-07 2019-06-06 4 INCY INCYTE CORP
Common Stock 		J - Other 220,141 281,190 360.60
2019-06-07 2019-06-06 4 INCY INCYTE CORP
Common Stock 		J - Other 220,141 281,190 360.60
2019-06-07 2019-06-06 4 INCY INCYTE CORP
Common Stock 		J - Other -692,706 0 -100.00
2019-06-07 2019-06-06 4 INCY INCYTE CORP
Common Stock 		J - Other -1,603,238 2,826,766 -36.19
2019-06-05 2019-06-03 4 KOD Kodiak Sciences Inc.
Non-Qualified Stock Option (right to buy) 		A - Award 24,747 24,747
2019-05-31 2019-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Non-Qualified Share Option (right to buy) 		A - Award 37,520 37,520
2019-05-31 2019-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Non-Qualified Share Option (right to buy) 		A - Award 37,520 37,520
2019-05-30 2019-05-30 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -22,720 7,382,978 -0.31 120.77 -2,743,928 891,653,328
2019-05-30 2019-05-30 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -2,729 952,874 -0.29 120.77 -329,585 115,080,022
2019-05-30 2019-05-30 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -13,213 7,405,698 -0.18 122.31 -1,616,054 905,775,370
2019-05-30 2019-05-30 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,587 955,603 -0.17 122.31 -194,103 116,877,796
2019-05-30 2019-05-30 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -15,355 7,418,911 -0.21 120.12 -1,844,459 891,167,750
2019-05-30 2019-05-30 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,845 957,190 -0.19 120.12 -221,623 114,978,716
2019-05-30 2019-05-29 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -35,796 7,434,266 -0.48 122.37 -4,380,432 909,746,742
2019-05-30 2019-05-29 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -4,300 959,035 -0.45 122.37 -526,200 117,359,127
2019-05-30 2019-05-29 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -30,766 7,470,062 -0.41 123.06 -3,786,036 919,259,107
2019-05-30 2019-05-29 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -3,696 963,335 -0.38 123.06 -454,826 118,547,138
2019-05-30 2019-05-29 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -39,732 7,500,828 -0.53 121.37 -4,822,189 910,359,743
2019-05-30 2019-05-29 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -4,772 967,031 -0.49 121.37 -579,168 117,366,522
2019-05-30 2019-05-28 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -71,819 7,540,560 -0.94 127.06 -9,125,258 958,096,767
2019-05-30 2019-05-28 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -8,627 971,803 -0.88 127.06 -1,096,139 123,476,415
2019-05-30 2019-05-28 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -22,886 7,612,379 -0.30 125.05 -2,861,901 951,930,278
2019-05-30 2019-05-28 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -2,749 980,430 -0.28 125.05 -343,763 122,603,066
2019-05-30 2019-05-28 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -15,541 7,635,265 -0.20 126.25 -1,962,085 963,969,004
2019-05-30 2019-05-28 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		S - Sale -1,867 983,179 -0.19 126.25 -235,713 124,128,512
2019-05-22 2019-05-20 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 7,038 7,038
2019-05-22 2019-05-20 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 7,038 7,038
2019-05-22 2019-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 2,963 45,842,649 0.01
2019-05-22 2019-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 2,963 45,842,649 0.01
2019-05-17 2019-05-15 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,726 7,650,806 0.04
2019-05-17 2019-05-15 4 ALXN ALEXION PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,726 7,650,806 0.04
2019-05-01 2019-04-29 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2019-05-01 2019-04-29 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2019-05-01 2019-04-29 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 45,839,686 0.02 8.38 83,800 384,136,569
2019-05-01 2019-04-29 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 45,839,686 0.02 8.38 83,800 384,136,569
2019-04-30 2019-04-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 12,472 12,472
2019-04-30 2019-04-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 12,472 12,472
2019-04-30 2019-04-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 12,472 12,472
2019-04-30 2019-04-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,520 812,602 0.19
2019-04-30 2019-04-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,520 812,602 0.19
2019-04-30 2019-04-26 4 INCY INCYTE CORP
Common Stock 		A - Award 1,520 812,602 0.19
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Class A Common Stock 		C - Conversion 529,758 529,758
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Series D Preferred Stock 		C - Conversion -529,758 0 -100.00
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Class A Common Stock 		C - Conversion 60,194 60,194
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Series D Preferred Stock 		C - Conversion -60,194 0 -100.00
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Class A Common Stock 		C - Conversion 2,905,359 2,905,359
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Series C Preferred Stock 		C - Conversion -2,905,359 0 -100.00
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Class A Common Stock 		C - Conversion 324,421 324,421
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Series C Preferred Stock 		C - Conversion -324,421 0 -100.00
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Common Stock 		P - Purchase 820,729 820,729 14.00 11,490,206 11,490,206
2019-04-23 2019-04-23 4 HOOK HOOKIPA Pharma Inc.
Common Stock 		P - Purchase 72,128 72,128 14.00 1,009,792 1,009,792
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,232 7,639,338 -0.12 65.32 -603,070 499,031,352
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,417 1,214,575 -0.12 65.32 -92,564 79,340,776
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -244 241,891 -0.10 65.32 -15,939 15,801,263
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -142 157,519 -0.09 65.32 -9,276 10,289,755
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11 49,893 -0.02 65.32 -719 3,259,205
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -158 171,091 -0.09 65.32 -10,321 11,176,331
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -63,775 7,648,570 -0.83 67.13 -4,281,177 513,443,915
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,791 1,215,992 -0.80 67.13 -657,264 81,628,813
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,688 242,135 -0.69 67.13 -113,314 16,254,377
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -979 157,661 -0.62 67.13 -65,720 10,583,688
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -74 49,904 -0.15 67.13 -4,968 3,350,026
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,093 171,249 -0.63 67.13 -73,372 11,495,843
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -173,085 7,712,345 -2.19 64.62 -11,184,701 498,369,420
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -26,575 1,225,783 -2.12 64.62 -1,717,269 79,209,730
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,581 243,823 -1.84 64.62 -296,023 15,755,769
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,656 158,640 -1.65 64.62 -171,630 10,251,269
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -202 49,978 -0.40 64.62 -13,053 3,229,563
2019-04-12 2019-04-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,966 172,342 -1.69 64.62 -191,662 11,136,688
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -106,054 7,885,430 -1.33 66.61 -7,063,981 525,227,990
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -16,282 1,252,358 -1.28 66.61 -1,084,502 83,416,310
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,807 248,404 -1.12 66.61 -186,967 16,545,545
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,628 161,296 -1.00 66.61 -108,437 10,743,507
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -124 50,180 -0.25 66.61 -8,259 3,342,359
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,817 175,308 -1.03 66.61 -121,026 11,676,810
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -60,618 7,991,484 -0.75 67.42 -4,086,914 538,792,244
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,307 1,268,640 -0.73 67.42 -627,485 85,532,724
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,604 251,211 -0.63 67.42 -108,143 16,936,847
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -930 162,924 -0.57 67.42 -62,701 10,984,466
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -71 50,304 -0.14 67.42 -4,787 3,391,536
2019-04-12 2019-04-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,039 177,125 -0.58 67.42 -70,050 11,941,909
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10,832 8,052,102 -0.13 69.12 -748,735 556,581,420
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,663 1,277,947 -0.13 69.12 -114,951 88,334,892
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -287 252,815 -0.11 69.12 -19,838 17,475,205
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -166 163,854 -0.10 69.12 -11,474 11,325,998
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13 50,375 -0.03 69.12 -899 3,482,046
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -185 178,164 -0.10 69.12 -12,788 12,315,141
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -102,618 8,062,934 -1.26 68.70 -7,049,918 553,928,404
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15,755 1,279,610 -1.22 68.70 -1,082,378 87,909,975
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,716 253,102 -1.06 68.70 -186,591 17,388,259
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,575 164,020 -0.95 68.70 -108,203 11,268,272
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -120 50,388 -0.24 68.70 -8,244 3,461,686
2019-04-10 2019-04-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,758 178,349 -0.98 68.70 -120,776 12,252,683
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15,543 8,165,552 -0.19 67.68 -1,051,888 552,611,897
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,386 1,295,365 -0.18 67.68 -161,475 87,665,122
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -411 255,818 -0.16 67.68 -27,815 17,312,739
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -239 165,595 -0.14 67.68 -16,175 11,206,807
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18 50,508 -0.04 67.68 -1,218 3,418,179
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -266 180,107 -0.15 67.68 -18,002 12,188,921
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,813 8,181,095 -0.02 67.87 -123,047 555,244,373
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -278 1,297,751 -0.02 67.87 -18,868 88,077,322
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -48 256,229 -0.02 67.87 -3,258 17,390,057
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -28 165,834 -0.02 67.87 -1,900 11,255,021
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2 50,526 0.00 67.87 -136 3,429,159
2019-04-10 2019-04-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -31 180,373 -0.02 67.87 -2,104 12,241,771
2019-04-10 2019-04-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18,661 8,182,908 -0.23 67.90 -1,267,017 555,590,813
2019-04-10 2019-04-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,865 1,298,029 -0.22 67.90 -194,523 88,131,626
2019-04-10 2019-04-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -494 256,277 -0.19 67.90 -33,541 17,400,311
2019-04-10 2019-04-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -286 165,862 -0.17 67.90 -19,418 11,261,449
2019-04-10 2019-04-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -22 50,528 -0.04 67.90 -1,494 3,430,674
2019-04-10 2019-04-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -320 180,404 -0.18 67.90 -21,727 12,248,800
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -42,863 8,201,569 -0.52 68.72 -2,945,370 563,578,195
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,581 1,300,894 -0.50 68.72 -452,219 89,392,102
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,134 256,771 -0.44 68.72 -77,924 17,644,250
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -658 166,148 -0.39 68.72 -45,215 11,417,009
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -50 50,550 -0.10 68.72 -3,436 3,473,589
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -734 180,724 -0.40 68.72 -50,437 12,418,612
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -21,116 8,244,432 -0.26 68.63 -1,449,147 565,798,055
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,242 1,307,475 -0.25 68.63 -222,492 89,729,264
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -559 257,905 -0.22 68.63 -38,363 17,699,479
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -324 166,806 -0.19 68.63 -22,235 11,447,545
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -25 50,600 -0.05 68.63 -1,716 3,472,572
2019-04-05 2019-04-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -362 181,458 -0.20 68.63 -24,843 12,453,081
2019-04-05 2019-04-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -66,784 8,265,548 -0.80 66.64 -4,450,459 550,812,813
2019-04-05 2019-04-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10,253 1,310,717 -0.78 66.64 -683,256 87,345,657
2019-04-05 2019-04-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,768 258,464 -0.68 66.64 -117,819 17,223,938
2019-04-05 2019-04-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,025 167,130 -0.61 66.64 -68,306 11,137,476
2019-04-05 2019-04-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -78 50,625 -0.15 66.64 -5,198 3,373,630
2019-04-05 2019-04-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,145 181,820 -0.63 66.64 -76,302 12,116,412
2019-04-05 2019-04-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -80,146 8,332,332 -0.95 68.90 -5,521,963 574,087,676
2019-04-05 2019-04-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -12,305 1,320,970 -0.92 68.90 -847,800 91,013,248
2019-04-05 2019-04-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,121 260,232 -0.81 68.90 -146,134 17,929,673
2019-04-05 2019-04-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,230 168,155 -0.73 68.90 -84,746 11,585,678
2019-04-05 2019-04-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -93 50,703 -0.18 68.90 -6,408 3,493,376
2019-04-05 2019-04-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,374 182,965 -0.75 68.90 -94,667 12,606,069
2019-04-03 2019-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 4,161 89,233 4.89 2.59 10,777 231,113
2019-04-03 2019-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 4,161 89,233 4.89 2.59 10,777 231,113
2019-04-03 2019-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 4,161 4,288,031 0.10 2.59 10,777 11,106,000
2019-04-03 2019-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 298 8,412,478 0.00 66.84 19,918 562,290,030
2019-04-03 2019-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 298 8,412,478 0.00 66.84 19,918 562,290,030
2019-04-03 2019-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 298 1,507,172 0.02 66.84 19,918 100,739,376
2019-04-03 2019-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 298 436,250 0.07 66.84 19,918 29,158,950
2019-04-03 2019-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 298 343,282 0.09 66.84 19,918 22,944,969
2019-04-03 2019-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 298 224,693 0.13 66.84 19,918 15,018,480
2019-04-02 2019-03-29 4 INCY INCYTE CORP
Common Stock 		A - Award 220 811,082 0.03 86.01 18,922 69,761,163
2019-04-02 2019-03-29 4 INCY INCYTE CORP
Common Stock 		A - Award 220 811,082 0.03 86.01 18,922 69,761,163
2019-04-02 2019-03-29 4 INCY INCYTE CORP
Common Stock 		A - Award 220 811,082 0.03 86.01 18,922 69,761,163
2019-03-25 2019-03-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -46,678 8,412,180 -0.55 74.71 -3,487,122 628,439,478
2019-03-25 2019-03-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7,167 1,332,977 -0.53 74.71 -535,417 99,581,246
2019-03-25 2019-03-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,235 262,055 -0.47 74.71 -92,262 19,577,055
2019-03-25 2019-03-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -716 169,087 -0.42 74.71 -53,489 12,631,797
2019-03-25 2019-03-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -55 50,498 -0.11 74.71 -4,109 3,772,499
2019-03-25 2019-03-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -800 184,041 -0.43 74.71 -59,765 13,748,949
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -41,281 8,458,858 -0.49 74.34 -3,068,962 628,858,572
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,338 1,340,144 -0.47 74.34 -471,187 99,630,593
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,092 263,290 -0.41 74.34 -81,183 19,573,821
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -634 169,803 -0.37 74.34 -47,134 12,623,698
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -48 50,553 -0.09 74.34 -3,568 3,758,272
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -707 184,841 -0.38 74.34 -52,561 13,741,671
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -86,620 8,500,139 -1.01 74.63 -6,464,529 634,373,024
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13,298 1,346,482 -0.98 74.63 -992,442 100,489,163
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,293 264,382 -0.86 74.63 -171,129 19,731,067
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,329 170,437 -0.77 74.63 -99,184 12,719,867
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -101 50,601 -0.20 74.63 -7,538 3,776,398
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,485 185,548 -0.79 74.63 -110,827 13,847,614
2019-03-19 2019-03-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -90,251 8,586,759 -1.04 74.19 -6,695,487 637,029,325
2019-03-19 2019-03-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13,856 1,359,780 -1.01 74.19 -1,027,941 100,878,543
2019-03-19 2019-03-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,388 266,675 -0.89 74.19 -177,160 19,783,925
2019-03-19 2019-03-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,385 171,766 -0.80 74.19 -102,750 12,742,873
2019-03-19 2019-03-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -106 50,702 -0.21 74.19 -7,864 3,761,450
2019-03-19 2019-03-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,547 187,033 -0.82 74.19 -114,768 13,875,492
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -413 8,677,010 0.00 74.56 -30,795 647,001,251
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -63 1,373,636 0.00 74.56 -4,698 102,425,168
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11 269,063 0.00 74.56 -820 20,062,683
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6 173,151 0.00 74.56 -447 12,911,004
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7 188,580 0.00 74.56 -522 14,061,468
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -42,124 8,677,423 -0.48 74.50 -3,138,238 646,468,014
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,467 1,373,699 -0.47 74.50 -481,792 102,340,576
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,115 269,074 -0.41 74.50 -83,068 20,046,013
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -647 173,157 -0.37 74.50 -48,202 12,900,196
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -49 50,808 -0.10 74.50 -3,650 3,785,196
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -722 188,587 -0.38 74.50 -53,789 14,049,732
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,068 8,719,547 -0.04 76.57 -234,915 667,649,610
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -471 1,380,166 -0.03 76.57 -36,064 105,678,345
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -81 270,189 -0.03 76.57 -6,202 20,688,183
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -47 173,804 -0.03 76.57 -3,599 13,308,051
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 50,857 -0.01 76.57 -306 3,894,085
2019-03-19 2019-03-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -52 189,309 -0.03 76.57 -3,982 14,495,258
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -41,281 8,458,858 -0.49 74.34 -3,068,962 628,858,572
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,338 1,340,144 -0.47 74.34 -471,187 99,630,593
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,092 263,290 -0.41 74.34 -81,183 19,573,821
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -634 169,803 -0.37 74.34 -47,134 12,623,698
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -48 50,553 -0.09 74.34 -3,568 3,758,272
2019-03-19 2019-03-19 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -707 184,841 -0.38 74.34 -52,561 13,741,671
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,648 8,722,615 -0.02 76.03 -125,301 663,197,864
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -253 1,380,637 -0.02 76.03 -19,236 104,972,592
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -44 270,270 -0.02 76.03 -3,345 20,549,169
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -25 173,851 -0.01 76.03 -1,901 13,218,239
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2 50,861 0.00 76.03 -152 3,867,064
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -28 189,361 -0.01 76.03 -2,129 14,397,496
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -51,987 8,724,263 -0.59 76.50 -3,977,031 667,410,482
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7,982 1,380,890 -0.57 76.50 -610,627 105,638,775
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,375 270,314 -0.51 76.50 -105,188 20,679,156
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -798 173,876 -0.46 76.50 -61,047 13,301,601
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -61 50,863 -0.12 76.50 -4,667 3,891,045
2019-03-14 2019-03-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -891 189,389 -0.47 76.50 -68,162 14,488,353
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -247 8,776,250 0.00 75.40 -18,624 661,729,250
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -39 1,388,872 0.00 75.40 -2,941 104,720,949
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7 271,689 0.00 75.40 -528 20,485,351
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 174,674 0.00 75.40 -302 13,170,420
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 174,674 0.00 75.40 -302 13,170,420
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 50,924 0.00 75.40 -75 3,839,670
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -63,047 8,776,497 -0.71 75.92 -4,786,390 666,292,344
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,679 1,388,911 -0.69 75.92 -734,808 105,443,068
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,668 271,696 -0.61 75.92 -126,631 20,626,563
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -967 174,678 -0.55 75.92 -73,413 13,261,169
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -73 50,925 -0.14 75.92 -5,542 3,866,114
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,080 190,284 -0.56 75.92 -81,991 14,445,943
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,832 8,839,544 -0.03 76.05 -215,369 672,232,294
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -435 1,398,590 -0.03 76.05 -33,081 106,360,392
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -75 273,364 -0.03 76.05 -5,704 20,788,867
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -43 175,645 -0.02 76.05 -3,270 13,357,504
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3 50,998 -0.01 76.05 -228 3,878,311
2019-03-14 2019-03-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -49 191,364 -0.03 76.05 -3,726 14,552,907
2019-03-14 2019-03-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -61,122 8,842,376 -0.69 75.63 -4,622,669 668,750,665
2019-03-14 2019-03-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,384 1,399,025 -0.67 75.63 -709,714 105,808,541
2019-03-14 2019-03-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,618 273,439 -0.59 75.63 -122,370 20,680,246
2019-03-14 2019-03-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -938 175,688 -0.53 75.63 -70,941 13,287,319
2019-03-14 2019-03-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -71 51,001 -0.14 75.63 -5,370 3,857,216
2019-03-14 2019-03-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,047 191,413 -0.54 75.63 -79,185 14,476,603
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,296 8,903,498 -0.04 74.03 -244,007 659,137,531
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -506 1,408,409 -0.04 74.03 -37,460 104,266,349
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -87 275,057 -0.03 74.03 -6,441 20,362,827
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -51 176,626 -0.03 74.03 -3,776 13,075,852
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 51,072 -0.01 74.03 -296 3,780,927
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -56 192,460 -0.03 74.03 -4,146 14,248,064
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -37,107 8,906,794 -0.41 75.08 -2,786,101 668,747,923
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,697 1,408,915 -0.40 75.08 -427,747 105,785,424
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -982 275,144 -0.36 75.08 -73,731 20,658,609
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -569 176,677 -0.32 75.08 -42,722 13,265,422
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -43 51,076 -0.08 75.08 -3,229 3,834,934
2019-03-11 2019-03-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -637 192,516 -0.33 75.08 -47,828 14,454,660
2019-03-11 2019-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18,703 8,943,901 -0.21 73.55 -1,375,551 657,797,981
2019-03-11 2019-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,872 1,414,612 -0.20 73.55 -211,227 104,040,610
2019-03-11 2019-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -495 276,126 -0.18 73.55 -36,406 20,308,267
2019-03-11 2019-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -287 177,246 -0.16 73.55 -21,108 13,035,929
2019-03-11 2019-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -22 51,119 -0.04 73.55 -1,618 3,759,654
2019-03-11 2019-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -321 193,153 -0.17 73.55 -23,609 14,205,843
2019-03-11 2019-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,647 8,962,604 -0.02 73.72 -121,421 660,745,573
2019-03-11 2019-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -253 1,417,484 -0.02 73.72 -18,652 104,500,464
2019-03-11 2019-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -44 276,621 -0.02 73.72 -3,244 20,393,192
2019-03-11 2019-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -25 177,533 -0.01 73.72 -1,843 13,088,177
2019-03-11 2019-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2 51,141 0.00 73.72 -147 3,770,242
2019-03-11 2019-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -29 193,474 -0.01 73.72 -2,138 14,263,387
2019-03-05 2019-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,486 8,964,251 -0.09 77.04 -653,755 690,598,726
2019-03-05 2019-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,303 1,417,737 -0.09 77.04 -100,382 109,221,324
2019-03-05 2019-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -225 276,665 -0.08 77.04 -17,334 21,314,050
2019-03-05 2019-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -130 177,558 -0.07 77.04 -10,015 13,678,926
2019-03-05 2019-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10 51,143 -0.02 77.04 -770 3,940,016
2019-03-05 2019-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -146 193,503 -0.08 77.04 -11,248 14,907,316
2019-03-05 2019-03-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -22,914 8,972,737 -0.25 76.49 -1,752,680 686,320,167
2019-03-05 2019-03-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,518 1,419,040 -0.25 76.49 -269,090 108,541,660
2019-03-05 2019-03-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -607 276,890 -0.22 76.49 -46,429 21,179,178
2019-03-05 2019-03-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -352 177,688 -0.20 76.49 -26,924 13,591,266
2019-03-05 2019-03-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -27 51,153 -0.05 76.49 -2,065 3,912,667
2019-03-05 2019-03-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -393 193,649 -0.20 76.49 -30,060 14,812,115
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -58,412 8,995,651 -0.65 77.15 -4,506,626 694,036,064
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,968 1,422,558 -0.63 77.15 -691,903 109,753,764
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,546 277,497 -0.55 77.15 -119,278 21,409,560
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -896 178,040 -0.50 77.15 -69,129 13,736,213
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -68 51,180 -0.13 77.15 -5,246 3,948,660
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,001 194,042 -0.51 77.15 -77,230 14,970,806
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,909 9,054,063 -0.08 77.64 -536,386 702,919,424
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,060 1,431,526 -0.07 77.64 -82,294 111,137,666
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -183 279,043 -0.07 77.64 -14,207 21,663,727
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -107 178,936 -0.06 77.64 -8,307 13,891,840
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8 51,248 -0.02 77.64 -621 3,978,679
2019-03-05 2019-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -118 195,043 -0.06 77.64 -9,161 15,142,319
2019-02-28 2019-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -493 9,060,972 -0.01 76.20 -37,565 690,423,414
2019-02-28 2019-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -76 1,432,586 -0.01 76.20 -5,791 109,159,472
2019-02-28 2019-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13 279,226 0.00 76.20 -991 21,276,323
2019-02-28 2019-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8 179,043 0.00 76.20 -610 13,642,629
2019-02-28 2019-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 51,256 0.00 76.20 -76 3,905,579
2019-02-28 2019-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9 195,161 0.00 76.20 -686 14,870,780
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -742 9,061,465 -0.01 76.20 -56,540 690,483,633
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -114 1,432,662 -0.01 76.20 -8,687 109,168,844
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -20 279,239 -0.01 76.20 -1,524 21,278,012
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11 179,051 -0.01 76.20 -838 13,643,686
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 51,257 0.00 76.20 -76 3,905,783
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13 195,170 -0.01 76.20 -991 14,871,954
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -31,482 9,062,207 -0.35 76.66 -2,413,501 694,735,069
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,833 1,432,776 -0.34 76.66 -370,512 109,840,763
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -833 279,259 -0.30 76.66 -63,860 21,408,805
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -484 179,062 -0.27 76.66 -37,105 13,727,412
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -37 51,258 -0.07 76.66 -2,837 3,929,587
2019-02-28 2019-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -539 195,183 -0.28 76.66 -41,321 14,963,295
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -620 9,093,689 -0.01 77.81 -48,239 707,539,019
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -95 1,437,609 -0.01 77.81 -7,392 111,853,887
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -16 280,092 -0.01 77.81 -1,245 21,792,698
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10 179,546 -0.01 77.81 -778 13,969,666
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 51,295 0.00 77.81 -78 3,991,033
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11 195,722 -0.01 77.81 -856 15,228,248
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,506 9,094,309 -0.07 78.13 -508,342 710,577,468
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -999 1,437,704 -0.07 78.13 -78,056 112,333,996
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -172 280,108 -0.06 78.13 -13,439 21,886,043
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -100 179,556 -0.06 78.13 -7,813 14,029,482
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8 51,296 -0.02 78.13 -625 4,007,977
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -112 195,733 -0.06 78.13 -8,751 15,293,461
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 9,100,815 0.09 17.59 145,118 160,083,336
2019-02-28 2019-02-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 9,100,815 0.09 17.59 145,118 160,083,336
2019-02-27 2019-02-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2019-02-27 2019-02-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2019-02-27 2019-02-26 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 29,288,793 0.07 2.80 56,000 82,008,620
2019-02-27 2019-02-26 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 29,288,793 0.07 2.80 56,000 82,008,620
2019-02-06 2019-02-04 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		A - Award 1,818,475 8,837,349 25.91
2019-02-06 2019-02-04 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		A - Award 181,525 916,043 24.71
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13,634 9,092,565 -0.15 70.55 -961,887 641,485,916
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,093 1,430,453 -0.15 70.55 -147,662 100,919,317
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -361 280,280 -0.13 70.55 -25,469 19,773,922
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -210 179,656 -0.12 70.55 -14,816 12,674,839
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -16 51,304 -0.03 70.55 -1,129 3,619,528
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -234 195,845 -0.12 70.55 -16,509 13,816,982
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -24,660 9,106,199 -0.27 71.35 -1,759,553 649,750,064
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,786 1,432,546 -0.26 71.35 -270,141 102,215,738
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -653 280,641 -0.23 71.35 -46,593 20,024,437
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -378 179,866 -0.21 71.35 -26,971 12,833,889
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -29 51,320 -0.06 71.35 -2,069 3,661,810
2019-01-30 2019-01-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -423 196,079 -0.22 71.35 -30,182 13,990,727
2019-01-25 2019-01-25 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -75,736 9,130,859 -0.82 72.20 -5,468,397 659,279,065
2019-01-25 2019-01-25 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11,627 1,436,332 -0.80 72.20 -839,509 103,708,054
2019-01-25 2019-01-25 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,004 281,294 -0.71 72.20 -144,696 20,310,383
2019-01-25 2019-01-25 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,162 180,244 -0.64 72.20 -83,900 13,014,230
2019-01-25 2019-01-25 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -89 51,349 -0.17 72.20 -6,426 3,707,572
2019-01-25 2019-01-25 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,298 196,502 -0.66 72.20 -93,720 14,188,113
2019-01-25 2019-01-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -65,426 9,206,595 -0.71 72.02 -4,711,967 663,057,131
2019-01-25 2019-01-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10,044 1,447,959 -0.69 72.02 -723,367 104,281,718
2019-01-25 2019-01-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,732 283,298 -0.61 72.02 -124,738 20,403,065
2019-01-25 2019-01-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,004 181,406 -0.55 72.02 -72,308 13,064,824
2019-01-25 2019-01-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -76 51,438 -0.15 72.02 -5,474 3,704,554
2019-01-25 2019-01-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,121 197,800 -0.56 72.02 -80,734 14,245,516
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,648 9,272,021 -0.02 73.46 -121,054 681,076,303
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -253 1,458,003 -0.02 73.46 -18,584 107,097,610
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -44 285,030 -0.02 73.46 -3,232 20,936,879
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -25 182,410 -0.01 73.46 -1,836 13,398,927
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2 51,514 0.00 73.46 -147 3,783,961
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -28 198,921 -0.01 73.46 -2,057 14,611,742
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -29,260 9,273,669 -0.31 70.52 -2,063,313 653,946,680
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,492 1,458,256 -0.31 70.52 -316,760 102,831,109
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -774 285,074 -0.27 70.52 -54,580 20,102,421
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -450 182,435 -0.25 70.52 -31,732 12,864,678
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -34 51,516 -0.07 70.52 -2,398 3,632,728
2019-01-25 2019-01-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -502 198,949 -0.25 70.52 -35,399 14,029,187
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -42,521 9,302,929 -0.45 71.00 -3,018,995 660,508,889
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,529 1,462,748 -0.44 71.00 -463,560 103,855,254
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,125 285,848 -0.39 71.00 -79,875 20,295,237
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -652 182,885 -0.36 71.00 -46,292 12,984,853
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -50 51,550 -0.10 71.00 -3,550 3,660,055
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -729 199,451 -0.36 71.00 -51,759 14,161,041
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10,547 9,345,450 -0.11 71.61 -755,298 669,251,973
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,619 1,469,277 -0.11 71.61 -115,941 105,218,746
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -279 286,973 -0.10 71.61 -19,980 20,550,883
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -162 183,537 -0.09 71.61 -11,601 13,143,562
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -12 51,600 -0.02 71.61 -859 3,695,210
2019-01-22 2019-01-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -181 200,180 -0.09 71.61 -12,962 14,335,410
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13,595 9,355,997 -0.15 72.23 -981,964 675,781,792
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,087 1,470,896 -0.14 72.23 -150,744 106,242,524
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -360 287,252 -0.13 72.23 -26,003 20,748,155
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -209 183,699 -0.11 72.23 -15,096 13,268,542
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -16 51,612 -0.03 72.23 -1,156 3,727,924
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -233 200,361 -0.12 72.23 -16,830 14,472,035
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -132,363 9,369,592 -1.39 72.79 -9,634,226 681,978,871
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -20,322 1,472,983 -1.36 72.79 -1,479,165 107,213,130
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,503 287,612 -1.20 72.79 -254,971 20,934,242
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,031 183,908 -1.09 72.79 -147,829 13,386,001
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -155 51,628 -0.30 72.79 -11,282 3,757,816
2019-01-22 2019-01-18 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,268 200,594 -1.12 72.79 -165,080 14,600,515
2019-01-22 2019-01-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -149,754 9,501,955 -1.55 70.79 -10,601,295 672,656,697
2019-01-22 2019-01-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -22,991 1,493,305 -1.52 70.79 -1,627,565 105,713,152
2019-01-22 2019-01-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,963 291,115 -1.34 70.79 -280,546 20,608,438
2019-01-22 2019-01-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,298 185,939 -1.22 70.79 -162,679 13,162,882
2019-01-22 2019-01-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -175 51,783 -0.34 70.79 -12,388 3,665,791
2019-01-22 2019-01-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,566 202,862 -1.25 70.79 -181,651 14,360,885
2019-01-14 2019-01-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -493 9,651,709 -0.01 70.07 -34,545 676,311,658
2019-01-14 2019-01-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -76 1,516,296 -0.01 70.07 -5,325 106,249,438
2019-01-14 2019-01-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13 295,078 0.00 70.07 -911 20,676,617
2019-01-14 2019-01-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8 188,237 0.00 70.07 -561 13,190,087
2019-01-14 2019-01-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 51,958 0.00 70.07 -70 3,640,785
2019-01-14 2019-01-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9 205,428 0.00 70.07 -631 14,394,689
2019-01-14 2019-01-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -23,462 9,652,202 -0.24 70.22 -1,647,574 677,807,546
2019-01-14 2019-01-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,602 1,516,372 -0.24 70.22 -252,944 106,484,343
2019-01-14 2019-01-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -621 295,091 -0.21 70.22 -43,609 20,722,205
2019-01-14 2019-01-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -360 188,245 -0.19 70.22 -25,280 13,219,147
2019-01-14 2019-01-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -27 51,959 -0.05 70.22 -1,896 3,648,722
2019-01-14 2019-01-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -402 205,437 -0.20 70.22 -28,230 14,426,423
2019-01-14 2019-01-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,392 9,675,664 -0.09 70.28 -589,772 679,985,347
2019-01-14 2019-01-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,288 1,519,974 -0.08 70.28 -90,518 106,820,581
2019-01-14 2019-01-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -222 295,712 -0.08 70.28 -15,602 20,782,018
2019-01-14 2019-01-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -129 188,605 -0.07 70.28 -9,066 13,254,763
2019-01-14 2019-01-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10 51,986 -0.02 70.28 -703 3,653,467
2019-01-14 2019-01-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -144 205,839 -0.07 70.28 -10,120 14,465,933
2019-01-04 2019-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,658 85,072 4.49 3.52 12,876 299,453
2019-01-04 2019-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,658 85,072 4.49 3.52 12,876 299,453
2019-01-04 2019-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,658 85,072 4.49 3.52 12,876 299,453
2019-01-03 2019-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 310 295,934 0.10 64.41 19,967 19,061,109
2019-01-03 2019-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 310 295,934 0.10 64.41 19,967 19,061,109
2019-01-03 2019-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 310 295,934 0.10 64.41 19,967 19,061,109
2019-01-03 2019-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 310 1,695,159 0.02 64.41 19,967 109,185,191
2019-01-03 2019-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 310 225,893 0.14 64.41 19,967 14,549,768
2019-01-03 2019-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 310 362,631 0.09 64.41 19,967 23,357,063
2019-01-02 2018-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 298 810,862 0.04 63.59 18,950 51,562,715
2019-01-02 2018-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 298 810,862 0.04 63.59 18,950 51,562,715
2019-01-02 2018-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 298 29,421,884 0.00 63.59 18,950 1,870,937,604
2018-12-12 2018-12-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15,243 9,683,746 -0.16 73.09 -1,114,047 707,744,323
2018-12-12 2018-12-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,340 1,520,952 -0.15 73.09 -171,021 111,159,994
2018-12-12 2018-12-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -403 295,624 -0.14 73.09 -29,454 21,605,917
2018-12-12 2018-12-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -234 188,424 -0.12 73.09 -17,102 13,771,119
2018-12-12 2018-12-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18 51,686 -0.03 73.09 -1,316 3,777,513
2018-12-12 2018-12-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -262 205,673 -0.13 73.09 -19,148 15,031,776
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -12,627 9,698,989 -0.13 71.81 -906,797 696,524,166
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,939 1,523,292 -0.13 71.81 -139,248 109,393,844
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -334 296,027 -0.11 71.81 -23,986 21,258,913
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -194 188,658 -0.10 71.81 -13,932 13,548,304
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15 51,704 -0.03 71.81 -1,077 3,713,076
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -216 205,935 -0.10 71.81 -15,512 14,789,037
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -34,794 9,711,616 -0.36 74.88 -2,605,510 727,243,681
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,342 1,525,231 -0.35 74.88 -400,030 114,215,246
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -921 296,361 -0.31 74.88 -68,968 22,192,667
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -534 188,852 -0.28 74.88 -39,988 14,141,974
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -41 51,719 -0.08 74.88 -3,070 3,872,920
2018-12-12 2018-12-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -597 206,151 -0.29 74.88 -44,706 15,437,391
2018-12-12 2018-12-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7,718 9,746,410 -0.08 73.83 -569,813 719,568,679
2018-12-12 2018-12-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,185 1,530,573 -0.08 73.83 -87,487 113,000,827
2018-12-12 2018-12-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -204 297,282 -0.07 73.83 -15,061 21,948,063
2018-12-12 2018-12-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -118 189,386 -0.06 73.83 -8,712 13,982,198
2018-12-12 2018-12-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9 51,760 -0.02 73.83 -664 3,821,394
2018-12-12 2018-12-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -132 206,748 -0.06 73.83 -9,745 15,264,019
2018-12-07 2018-12-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -84,418 9,754,128 -0.86 76.15 -6,428,768 742,815,864
2018-12-07 2018-12-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -12,961 1,531,758 -0.84 76.15 -987,032 116,649,499
2018-12-07 2018-12-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,234 297,486 -0.75 76.15 -170,128 22,654,749
2018-12-07 2018-12-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,296 189,504 -0.68 76.15 -98,696 14,431,488
2018-12-07 2018-12-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -99 51,769 -0.19 76.15 -7,539 3,942,416
2018-12-07 2018-12-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,447 206,880 -0.69 76.15 -110,195 15,754,740
2018-12-07 2018-12-06 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -76,364 9,838,546 -0.77 75.46 -5,762,481 742,423,568
2018-12-07 2018-12-06 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11,724 1,544,719 -0.75 75.46 -884,701 116,565,577
2018-12-07 2018-12-06 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,021 299,720 -0.67 75.46 -152,506 22,617,081
2018-12-07 2018-12-06 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,172 190,800 -0.61 75.46 -88,440 14,397,902
2018-12-07 2018-12-06 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -89 51,868 -0.17 75.46 -6,716 3,913,996
2018-12-07 2018-12-06 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,309 208,327 -0.62 75.46 -98,778 15,720,501
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,538 9,914,910 -0.03 77.75 -197,318 770,839,635
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -390 1,556,443 -0.03 77.75 -30,321 121,006,439
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -67 301,741 -0.02 77.75 -5,209 23,459,005
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -39 191,972 -0.02 77.75 -3,032 14,924,959
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3 51,957 -0.01 77.75 -233 4,039,423
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -43 209,636 -0.02 77.75 -3,343 16,298,256
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,493 9,917,448 -0.06 73.81 -405,449 732,025,680
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -843 1,556,833 -0.05 73.81 -62,223 114,912,802
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -146 301,808 -0.05 73.81 -10,777 22,277,022
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -84 192,011 -0.04 73.81 -6,200 14,172,697
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6 51,960 -0.01 73.81 -443 3,835,266
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -95 209,679 -0.05 73.81 -7,012 15,476,805
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18,604 9,922,941 -0.19 75.83 -1,410,758 752,465,547
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,856 1,557,676 -0.18 75.83 -216,573 118,119,973
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -492 301,954 -0.16 75.83 -37,309 22,897,444
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -286 192,095 -0.15 75.83 -21,688 14,566,737
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -21 51,966 -0.04 75.83 -1,592 3,940,629
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -319 209,774 -0.15 75.83 -24,190 15,907,351
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -371 9,941,545 0.00 77.11 -28,608 766,592,535
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -57 1,560,532 0.00 77.11 -4,395 120,332,623
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10 302,446 0.00 77.11 -771 23,321,611
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6 192,381 0.00 77.11 -463 14,834,499
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6 192,381 0.00 77.11 -463 14,834,499
2018-12-07 2018-12-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 51,987 0.00 77.11 -77 4,008,718
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock Warrant (right to buy) 		J - Other 1,569 1,569
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock Warrant (right to buy) 		J - Other 1,569 1,569
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock Warrant (right to buy) 		J - Other -10,731 0 -100.00
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		J - Other 71,647 71,647
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		J - Other 71,647 71,647
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		J - Other -489,977 0 -100.00
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 11,178,823 35,976,940 45.08 17.00 190,039,991 611,607,980
2018-12-04 2018-11-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 585,882 3,736,902 18.59 17.00 9,959,994 63,527,334
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -247 9,941,916 0.00 76.62 -18,925 761,724,749
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -38 1,560,589 0.00 76.62 -2,911 119,568,428
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6 302,456 0.00 76.62 -460 23,173,423
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 192,387 0.00 76.62 -306 14,740,211
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 192,387 0.00 76.62 -306 14,740,211
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1 51,988 0.00 76.62 -77 3,983,191
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -32,598 9,942,163 -0.33 77.52 -2,527,147 770,762,210
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,005 1,560,627 -0.32 77.52 -388,011 120,986,984
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -863 302,462 -0.28 77.52 -66,904 23,448,246
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -500 192,391 -0.26 77.52 -38,762 14,915,035
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -38 51,989 -0.07 77.52 -2,946 4,030,426
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -559 210,103 -0.27 77.52 -43,336 16,288,151
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -89,047 9,974,761 -0.88 78.05 -6,950,074 778,525,109
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13,671 1,565,632 -0.87 78.05 -1,067,015 122,196,795
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,357 303,325 -0.77 78.05 -183,963 23,674,365
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,367 192,891 -0.70 78.05 -106,694 15,055,046
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -104 52,027 -0.20 78.05 -8,117 4,060,681
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,526 210,662 -0.72 78.05 -119,104 16,442,064
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -44,659 10,063,808 -0.44 80.09 -3,576,721 806,006,357
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,856 1,579,303 -0.43 80.09 -549,094 126,485,746
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,182 305,682 -0.39 80.09 -94,666 24,481,949
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -685 194,258 -0.35 80.09 -54,861 15,558,046
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -52 52,131 -0.10 80.09 -4,165 4,175,151
2018-12-03 2018-12-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -765 212,188 -0.36 80.09 -61,269 16,994,052
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -129,121 10,108,467 -1.26 79.07 -10,209,675 799,282,551
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -19,824 1,586,159 -1.23 79.07 -1,567,496 125,418,544
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,417 306,864 -1.10 79.07 -270,184 24,263,921
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,981 194,943 -1.01 79.07 -156,639 15,414,260
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -151 52,183 -0.29 79.07 -11,940 4,126,141
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,214 212,953 -1.03 79.07 -175,062 16,838,321
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -39,591 10,237,588 -0.39 79.63 -3,152,536 815,194,562
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -6,078 1,605,983 -0.38 79.63 -483,977 127,880,572
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,048 310,281 -0.34 79.63 -83,450 24,706,931
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -608 196,924 -0.31 79.63 -48,414 15,680,586
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -46 52,334 -0.09 79.63 -3,663 4,167,231
2018-12-03 2018-11-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -678 215,167 -0.31 79.63 -53,988 17,133,232
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -30,257 10,277,179 -0.29 77.61 -2,348,376 797,656,054
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,646 1,612,061 -0.29 77.61 -360,596 125,118,986
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -801 311,329 -0.26 77.61 -62,169 24,163,582
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -465 197,532 -0.23 77.61 -36,091 15,331,308
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -35 52,380 -0.07 77.61 -2,717 4,065,437
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -518 215,845 -0.24 77.61 -40,204 16,752,659
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11,994 10,307,436 -0.12 78.80 -945,149 812,244,510
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,841 1,616,707 -0.11 78.80 -145,074 127,399,422
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -317 312,130 -0.10 78.80 -24,980 24,596,406
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -184 197,997 -0.09 78.80 -14,500 15,602,520
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -14 52,415 -0.03 78.80 -1,103 4,130,396
2018-12-03 2018-11-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -206 216,363 -0.10 78.80 -16,233 17,049,794
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -77,976 10,319,430 -0.75 76.81 -5,989,017 792,593,109
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11,972 1,618,548 -0.73 76.81 -919,520 124,314,036
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,064 312,447 -0.66 76.81 -158,527 23,997,773
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,197 198,181 -0.60 76.81 -91,937 15,221,470
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -91 52,429 -0.17 76.81 -6,989 4,026,857
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,335 216,569 -0.61 76.81 -102,536 16,633,777
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -13,595 10,397,406 -0.13 74.01 -1,006,150 769,499,541
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,087 1,630,520 -0.13 74.01 -154,456 120,672,829
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -360 314,511 -0.11 74.01 -26,643 23,276,582
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -209 199,378 -0.10 74.01 -15,468 14,755,727
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -16 52,520 -0.03 74.01 -1,184 3,886,942
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -233 217,904 -0.11 74.01 -17,244 16,126,814
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -57,979 10,411,001 -0.55 74.71 -4,331,524 777,790,268
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,901 1,632,607 -0.54 74.71 -664,980 121,969,620
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,534 314,871 -0.48 74.71 -114,603 23,523,540
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -890 199,587 -0.44 74.71 -66,491 14,910,845
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -68 52,536 -0.13 74.71 -5,080 3,924,886
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -994 218,137 -0.45 74.71 -74,260 16,296,688
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -56,764 10,468,980 -0.54 75.27 -4,272,831 788,037,813
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,715 1,641,508 -0.53 75.27 -656,009 123,562,217
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,502 316,405 -0.47 75.27 -113,061 23,816,943
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -871 200,477 -0.43 75.27 -65,563 15,090,626
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -66 52,604 -0.13 75.27 -4,968 3,959,692
2018-11-28 2018-11-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -973 219,131 -0.44 75.27 -73,241 16,494,779
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -36,652 10,525,744 -0.35 73.76 -2,703,294 776,333,617
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,627 1,650,223 -0.34 73.76 -415,023 121,713,353
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -970 317,907 -0.30 73.76 -71,543 23,447,453
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -563 201,348 -0.28 73.76 -41,524 14,850,563
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -43 52,670 -0.08 73.76 -3,171 3,884,713
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -628 220,104 -0.28 73.76 -46,319 16,233,925
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -77,558 10,562,396 -0.73 74.24 -5,758,092 784,177,629
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11,907 1,655,850 -0.71 74.24 -884,004 122,934,278
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,052 318,877 -0.64 74.24 -152,345 23,674,194
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,190 201,911 -0.59 74.24 -88,348 14,990,357
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -91 52,713 -0.17 74.24 -6,756 3,913,540
2018-11-28 2018-11-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,329 220,732 -0.60 74.24 -98,668 16,387,673
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,204 10,639,954 -0.08 74.05 -607,484 787,859,866
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,260 1,667,757 -0.08 74.05 -93,300 123,492,903
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -217 320,929 -0.07 74.05 -16,068 23,763,926
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -126 203,101 -0.06 74.05 -9,330 15,039,081
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -10 52,804 -0.02 74.05 -740 3,909,994
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -141 222,061 -0.06 74.05 -10,441 16,443,017
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -24,487 10,648,158 -0.23 74.36 -1,820,848 791,794,899
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,759 1,669,017 -0.22 74.36 -279,518 124,107,770
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -648 321,146 -0.20 74.36 -48,185 23,880,352
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -376 203,227 -0.18 74.36 -27,959 15,111,919
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -28 52,814 -0.05 74.36 -2,082 3,927,238
2018-11-28 2018-11-26 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -419 222,202 -0.19 74.36 -31,157 16,522,896
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -55,365 10,672,645 -0.52 76.35 -4,227,024 814,838,302
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,499 1,672,776 -0.51 76.35 -648,884 127,713,604
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,466 321,794 -0.45 76.35 -111,927 24,568,425
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -850 203,603 -0.42 76.35 -64,896 15,544,743
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -65 52,842 -0.12 76.35 -4,963 4,034,397
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -949 222,621 -0.42 76.35 -72,455 16,996,735
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -16,646 10,728,010 -0.15 77.66 -1,292,763 833,159,785
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,556 1,681,275 -0.15 77.66 -198,504 130,571,347
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -440 323,260 -0.14 77.66 -34,171 25,105,050
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -255 204,453 -0.12 77.66 -19,804 15,878,249
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -19 52,907 -0.04 77.66 -1,476 4,108,869
2018-11-20 2018-11-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -285 223,570 -0.13 77.66 -22,134 17,362,916
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -38,330 10,744,656 -0.36 79.13 -3,033,110 850,240,746
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,885 1,683,831 -0.35 79.13 -465,689 133,244,073
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,014 323,700 -0.31 79.13 -80,239 25,614,867
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -588 204,708 -0.29 79.13 -46,529 16,198,851
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -45 52,926 -0.08 79.13 -3,561 4,188,114
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -657 223,855 -0.29 79.13 -51,989 17,713,982
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,296 10,782,986 -0.03 80.09 -263,978 863,613,662
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -506 1,689,716 -0.03 80.09 -40,526 135,330,030
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -87 324,714 -0.03 80.09 -6,968 26,006,474
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -51 205,296 -0.02 80.09 -4,085 16,442,239
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 52,971 -0.01 80.09 -320 4,242,469
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -56 224,512 -0.02 80.09 -4,485 17,981,256
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -53,013 10,786,282 -0.49 80.07 -4,244,714 863,650,049
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,139 1,690,222 -0.48 80.07 -651,684 135,334,892
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,403 324,801 -0.43 80.07 -112,337 26,006,589
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -814 205,347 -0.39 80.07 -65,176 16,441,991
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -62 52,975 -0.12 80.07 -4,964 4,241,671
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -908 224,568 -0.40 80.07 -72,703 17,981,003
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -99,280 10,839,295 -0.91 78.09 -7,752,428 846,402,609
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15,242 1,698,361 -0.89 78.09 -1,190,194 132,619,066
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,628 326,204 -0.80 78.09 -205,211 25,472,129
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,524 206,161 -0.73 78.09 -119,004 16,098,391
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -115 53,037 -0.22 78.09 -8,980 4,141,474
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,702 225,476 -0.75 78.09 -132,903 17,606,632
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15,014 10,938,575 -0.14 81.26 -1,220,038 888,868,604
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,305 1,713,603 -0.13 81.26 -187,304 139,247,380
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -397 328,832 -0.12 81.26 -32,260 26,720,888
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -230 207,685 -0.11 81.26 -18,690 16,876,483
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18 53,152 -0.03 81.26 -1,463 4,319,132
2018-11-13 2018-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -257 227,178 -0.11 81.26 -20,884 18,460,484
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -46,511 10,953,589 -0.42 81.16 -3,774,912 889,011,904
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7,140 1,715,908 -0.41 81.16 -579,495 139,266,010
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,231 329,229 -0.37 81.16 -99,910 26,720,785
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -714 207,915 -0.34 81.16 -57,949 16,874,735
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -54 53,170 -0.10 81.16 -4,383 4,315,368
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -796 227,435 -0.35 81.16 -64,605 18,459,011
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -7,533 11,000,100 -0.07 80.51 -606,473 885,604,851
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,156 1,723,048 -0.07 80.51 -93,068 138,720,527
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -199 330,460 -0.06 80.51 -16,021 26,604,938
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -116 208,629 -0.06 80.51 -9,339 16,796,470
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9 53,224 -0.02 80.51 -725 4,285,000
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -129 228,231 -0.06 80.51 -10,386 18,374,604
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11,877 11,007,633 -0.11 80.38 -954,711 884,828,765
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,824 1,724,204 -0.11 80.38 -146,619 138,597,035
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -314 330,659 -0.09 80.38 -25,240 26,579,429
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -182 208,745 -0.09 80.38 -14,630 16,779,591
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -14 53,233 -0.03 80.38 -1,125 4,279,039
2018-11-13 2018-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -204 228,360 -0.09 80.38 -16,398 18,356,308
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -19,367 11,019,510 -0.18 85.11 -1,648,296 937,853,967
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,973 1,726,028 -0.17 85.11 -253,028 146,899,654
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -513 330,973 -0.15 85.11 -43,661 28,168,616
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -297 208,927 -0.14 85.11 -25,277 17,781,464
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -23 53,247 -0.04 85.11 -1,957 4,531,772
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -332 228,564 -0.15 85.11 -28,256 19,452,739
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -112,010 11,038,877 -1.00 82.06 -9,191,025 905,799,468
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -17,198 1,729,001 -0.98 82.06 -1,411,189 141,873,869
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,964 331,486 -0.89 82.06 -243,212 27,200,216
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,720 209,224 -0.82 82.06 -141,135 17,167,959
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -129 53,270 -0.24 82.06 -10,585 4,371,091
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,919 228,896 -0.83 82.06 -157,464 18,782,153
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -8,157 11,150,887 -0.07 82.55 -673,321 920,452,198
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,252 1,746,199 -0.07 82.55 -103,347 144,140,346
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -216 334,450 -0.06 82.55 -17,830 27,607,242
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -125 210,944 -0.06 82.55 -10,318 17,412,415
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9 53,399 -0.02 82.55 -743 4,407,831
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -140 230,815 -0.06 82.55 -11,556 19,052,670
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,120 11,159,044 -0.04 83.90 -345,678 936,271,689
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -633 1,747,451 -0.04 83.90 -53,110 146,615,508
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -109 334,666 -0.03 83.90 -9,145 28,079,314
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -63 211,069 -0.03 83.90 -5,286 17,709,217
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5 53,408 -0.01 83.90 -420 4,481,065
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -71 230,955 -0.03 83.90 -5,957 19,377,702
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -62,929 11,163,164 -0.56 83.20 -5,235,598 928,758,500
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,661 1,748,084 -0.55 83.20 -803,781 145,437,967
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,665 334,775 -0.49 83.20 -138,526 27,852,778
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -966 211,132 -0.46 83.20 -80,370 17,565,866
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -74 53,413 -0.14 83.20 -6,157 4,443,881
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,078 231,026 -0.46 83.20 -89,688 19,221,017
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -17,602 11,226,093 -0.16 85.87 -1,511,565 964,036,246
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,702 1,757,745 -0.15 85.87 -232,033 150,945,649
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -466 336,440 -0.14 85.87 -40,018 28,891,650
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -270 212,098 -0.13 85.87 -23,186 18,213,831
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -21 53,487 -0.04 85.87 -1,803 4,593,175
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -302 232,104 -0.13 85.87 -25,934 19,931,838
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,120 11,243,695 -0.04 82.00 -337,840 921,982,990
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -633 1,760,447 -0.04 82.00 -51,906 144,356,654
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -109 336,906 -0.03 82.00 -8,938 27,626,292
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -63 212,368 -0.03 82.00 -5,166 17,414,176
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5 53,508 -0.01 82.00 -410 4,387,656
2018-11-13 2018-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -71 232,406 -0.03 82.00 -5,822 19,057,292
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,565 11,247,815 -0.01 83.85 -131,227 943,138,286
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -240 1,761,080 -0.01 83.85 -20,124 147,667,967
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -42 337,015 -0.01 83.85 -3,522 28,258,977
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -24 212,431 -0.01 83.85 -2,012 17,812,509
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2 53,513 0.00 83.85 -168 4,487,108
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -27 232,477 -0.01 83.85 -2,264 19,493,382
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -9,301 11,249,380 -0.08 84.84 -789,121 954,426,648
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -1,428 1,761,320 -0.08 84.84 -121,155 149,434,968
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -246 337,057 -0.07 84.84 -20,871 28,596,792
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -143 212,455 -0.07 84.84 -12,132 18,025,235
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -11 53,515 -0.02 84.84 -933 4,540,352
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -159 232,504 -0.07 84.84 -13,490 19,726,244
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -21,423 11,258,681 -0.19 89.34 -1,913,901 1,005,834,798
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,289 1,762,748 -0.19 89.34 -293,835 157,481,438
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -567 337,303 -0.17 89.34 -50,655 30,134,178
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -329 212,598 -0.15 89.34 -29,392 18,993,208
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -25 53,526 -0.05 89.34 -2,233 4,781,938
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -367 232,663 -0.16 89.34 -32,787 20,785,787
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -30,555 11,280,104 -0.27 85.15 -2,601,670 960,468,143
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,692 1,766,037 -0.26 85.15 -399,510 150,372,929
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -809 337,870 -0.24 85.15 -68,884 28,768,651
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -470 212,927 -0.22 85.15 -40,019 18,130,117
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -37 53,551 -0.07 85.15 -3,150 4,559,712
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -522 233,030 -0.22 85.15 -44,447 19,841,829
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -36,174 11,310,659 -0.32 85.78 -3,102,970 970,217,018
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5,554 1,770,729 -0.31 85.78 -476,417 151,891,363
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -957 338,679 -0.28 85.78 -82,091 29,051,546
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -555 213,397 -0.26 85.78 -47,607 18,304,981
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -42 53,588 -0.08 85.78 -3,603 4,596,725
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -620 233,552 -0.26 85.78 -53,183 20,033,857
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -3,663 11,346,833 -0.03 87.30 -319,780 990,579,656
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -562 1,776,283 -0.03 87.30 -49,063 155,069,684
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -97 339,636 -0.03 87.30 -8,468 29,650,257
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -56 213,952 -0.03 87.30 -4,889 18,678,031
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4 53,630 -0.01 87.30 -349 4,681,904
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -63 234,172 -0.03 87.30 -5,500 20,443,239
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -4,306 11,350,496 -0.04 88.38 -380,544 1,003,104,624
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -661 1,776,845 -0.04 88.38 -58,416 157,029,388
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -114 339,733 -0.03 88.38 -10,075 30,024,040
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -66 214,008 -0.03 88.38 -5,833 18,913,043
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -5 53,634 -0.01 88.38 -442 4,739,926
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -74 234,235 -0.03 88.38 -6,540 20,700,612
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -15,798 11,354,802 -0.14 83.94 -1,326,160 953,176,583
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -2,425 1,777,506 -0.14 83.94 -203,566 149,212,386
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -418 339,847 -0.12 83.94 -35,089 28,528,388
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -242 214,074 -0.11 83.94 -20,315 17,970,399
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -18 53,639 -0.03 83.94 -1,511 4,502,715
2018-11-13 2018-11-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		S - Sale -271 234,309 -0.12 83.94 -22,749 19,669,022
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Secured Bridge Notes 30% 12/1/2020 		C - Conversion -3,660,993 0 -100.00
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Secured Bridge Notes 30% 12/1/2020 		C - Conversion -294,948 0 -100.00
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Series B Redeemable Convertible Preferred Shares 		C - Conversion -4,627,208 0 -100.00
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Series B Redeemable Convertible Preferred Shares 		C - Conversion -372,792 0 -100.00
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 2,248,102 8,374,935 36.69 10.00 22,481,020 83,749,350
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		P - Purchase 251,898 770,180 48.60 10.00 2,518,980 7,701,800
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		J - Other 767,427 6,126,833 14.32
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		J - Other 86,501 518,282 20.03
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		C - Conversion 732,198 5,359,406 15.82 5.00 3,660,990 26,797,030
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		C - Conversion 58,989 431,781 15.82 5.00 294,945 2,158,905
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		C - Conversion 4,627,208 4,627,208
2018-10-11 2018-10-09 4 KOD Kodiak Sciences Inc.
Common Stock 		C - Conversion 372,792 372,792
2018-10-03 2018-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 284 340,265 0.08 70.18 19,931 23,879,798
2018-10-03 2018-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 284 340,265 0.08 70.18 19,931 23,879,798
2018-10-03 2018-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 284 11,544,497 0.00 70.18 19,931 810,192,799
2018-10-03 2018-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 284 1,953,828 0.01 70.18 19,931 137,119,649
2018-10-03 2018-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 284 227,554 0.12 70.18 19,931 15,969,740
2018-10-03 2018-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 284 388,213 0.07 70.18 19,931 27,244,788
2018-10-03 2018-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,340 81,414 2.96 8.71 20,381 709,116
2018-10-03 2018-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,340 81,414 2.96 8.71 20,381 709,116
2018-10-03 2018-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 2,340 4,280,212 0.05 8.71 20,381 37,280,647
2018-10-02 2018-09-28 4 INCY INCYTE CORP
Common Stock 		A - Award 275 810,564 0.03 69.08 18,997 55,993,761
2018-10-02 2018-09-28 4 INCY INCYTE CORP
Common Stock 		A - Award 275 810,564 0.03 69.08 18,997 55,993,761
2018-10-02 2018-09-28 4 INCY INCYTE CORP
Common Stock 		A - Award 275 1,269,837 0.02 69.08 18,997 87,720,340
2018-09-24 2018-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 131,007 24,798,117 0.53 19.09 2,501,238 473,455,569
2018-09-24 2018-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 14,555 3,151,020 0.46 19.09 277,890 60,160,534
2018-09-24 2018-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 38,207 24,667,110 0.16 19.01 726,353 468,946,428
2018-09-24 2018-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 4,245 3,136,465 0.14 19.01 80,702 59,627,336
2018-09-24 2018-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 920,495 24,628,903 3.88 18.64 17,154,897 458,999,014
2018-09-24 2018-09-20 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 102,267 3,132,220 3.38 18.64 1,905,909 58,373,931
2018-08-06 2018-08-02 4 BGNE BeiGene, Ltd.
Ordinary shares 		P - Purchase 5,231,900 5,250,491 28,142.11 108.00 565,045,200 567,053,028
2018-08-06 2018-08-02 4 BGNE BeiGene, Ltd.
Ordinary shares 		P - Purchase 582,200 600,791 3,131.62 108.00 62,877,600 64,885,428
2018-07-05 2018-07-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 16,383 632,599 2.66 1.32 21,626 835,031
2018-07-05 2018-07-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 16,383 632,599 2.66 1.32 21,626 835,031
2018-07-05 2018-07-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 16,383 34,222,983 0.05 1.32 21,626 45,174,338
2018-07-03 2018-06-29 4 INCY INCYTE CORP
Common Stock 		A - Award 283 810,289 0.03 67.00 18,961 54,289,363
2018-07-03 2018-06-29 4 INCY INCYTE CORP
Common Stock 		A - Award 283 810,289 0.03 67.00 18,961 54,289,363
2018-07-03 2018-06-29 4 INCY INCYTE CORP
Common Stock 		A - Award 283 810,289 0.03 67.00 18,961 54,289,363
2018-07-03 2018-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 396 339,981 0.12 50.40 19,958 17,135,042
2018-07-03 2018-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 396 339,981 0.12 50.40 19,958 17,135,042
2018-07-03 2018-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 396 339,981 0.12 50.40 19,958 17,135,042
2018-07-03 2018-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 396 1,953,544 0.02 50.40 19,958 98,458,618
2018-07-03 2018-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 396 227,270 0.17 50.40 19,958 11,454,408
2018-07-03 2018-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 396 387,929 0.10 50.40 19,958 19,551,622
2018-06-21 2018-06-20 4 IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 100,000 100,000
2018-06-11 2018-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		A - Award 20,000 20,000
2018-06-08 2018-06-06 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 30,000 30,000
2018-06-08 2018-06-06 4 BGNE BeiGene, Ltd.
Share Option (Right to Buy) 		A - Award 34,884 34,884
2018-06-08 2018-06-06 4 BGNE BeiGene, Ltd.
Ordinary shares 		A - Award 18,580 73,180,602 0.03
2018-06-08 2018-06-06 4 BGNE BeiGene, Ltd.
Ordinary shares 		A - Award 18,580 73,180,602 0.03
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class B1 Common Shares 		C - Conversion 14,658,102 14,658,102
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series A Preferred 		C - Conversion -14,658,102 0 -100.00
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class B1 Common Shares 		C - Conversion 1,399,516 1,399,516
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series A Preferred 		C - Conversion -1,399,516 0 -100.00
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		C - Conversion 3,284,771 7,018,874 87.97
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series B Preferred 		C - Conversion -3,284,771 0 -100.00
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		C - Conversion 313,621 734,518 74.51
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series B Preferred 		C - Conversion -313,621 0 -100.00
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		C - Conversion 3,734,103 3,734,103
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series C Preferred 		C - Conversion -3,734,103 0 -100.00
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A1 Common Shares 		C - Conversion 420,897 420,897
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series C Preferred 		C - Conversion -420,897 0 -100.00
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		P - Purchase 2,700,597 2,700,597 18.00 48,610,746 48,610,746
2018-05-31 2018-05-29 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Class A Common Shares 		P - Purchase 299,403 299,403 18.00 5,389,254 5,389,254
2018-05-31 2018-02-09 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series C Preferred 		P - Purchase 3,734,103 3,734,103
2018-05-31 2018-02-09 4 KNSA Kiniksa Pharmaceuticals, Ltd.
Series C Preferred 		P - Purchase 420,897 420,897
2018-05-18 2018-05-18 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2018-05-18 2018-05-18 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2018-05-18 2018-05-18 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 45,829,686 0.01 56.77 210,049 2,601,751,274
2018-05-18 2018-05-18 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 45,829,686 0.01 56.77 210,049 2,601,751,274
2018-05-11 2018-05-09 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 2,174 7,648,080 0.03
2018-05-11 2018-05-09 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 2,174 7,648,080 0.03
2018-05-09 2018-05-07 4 AQXP AQUINOX PHARMACEUTICALS, INC
Non-Qualified Stock Option (right to buy) 		A - Award 30,000 30,000
2018-05-08 2018-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 126,399 45,825,986 0.28 54.02 6,828,339 2,475,615,998
2018-05-08 2018-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 129,715 45,699,587 0.28 53.70 6,966,305 2,454,282,610
2018-05-08 2018-05-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 204,537 45,569,872 0.45 52.68 10,775,582 2,400,748,453
2018-05-03 2018-05-02 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2018-05-03 2018-05-02 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2018-05-03 2018-05-02 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2018-05-03 2018-05-02 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 810,006 2.53 9.92 198,400 8,035,260
2018-05-03 2018-05-02 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 810,006 2.53 9.92 198,400 8,035,260
2018-05-03 2018-05-02 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 810,006 2.53 9.92 198,400 8,035,260
2018-05-03 2018-05-01 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 15,000 15,000
2018-05-02 2018-05-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,105 45,365,335 0.02 54.42 495,488 2,468,749,775
2018-05-02 2018-05-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,442 45,356,230 0.05 52.26 1,120,576 2,370,352,865
2018-05-02 2018-05-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 37,400 45,334,788 0.08 52.33 1,957,022 2,372,224,385
2018-05-02 2018-05-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,000 45,297,388 0.00 51.88 103,750 2,349,802,002
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,951 45,295,388 0.01 52.33 311,418 2,370,321,243
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 37,963 45,289,437 0.08 52.06 1,976,213 2,357,600,519
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 57,270 45,251,474 0.13 51.37 2,941,708 2,324,369,113
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,500 45,194,204 0.02 51.36 539,280 2,321,174,317
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 22,700 45,183,704 0.05 51.30 1,164,424 2,317,752,317
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 72,533 45,161,004 0.16 51.26 3,717,693 2,314,736,292
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 100,000 45,088,471 0.22 51.14 5,114,000 2,305,824,407
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 44,988,471 0.02 10.08 100,800 453,483,788
2018-05-02 2018-05-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 44,988,471 0.02 10.08 100,800 453,483,788
2018-05-02 2018-04-30 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2018-05-02 2018-04-30 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2018-05-02 2018-04-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 168,097 44,978,471 0.38 51.25 8,614,786 2,305,097,162
2018-05-02 2018-04-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 52,700 44,810,374 0.12 51.07 2,691,173 2,288,282,078
2018-05-02 2018-04-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 248,121 44,757,674 0.56 51.03 12,661,069 2,283,885,637
2018-05-02 2018-04-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 154,218 44,509,553 0.35 50.90 7,849,897 2,265,594,110
2018-04-04 2018-04-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 13,349 616,216 2.21 1.62 21,625 998,270
2018-04-04 2018-04-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 13,349 616,216 2.21 1.62 21,625 998,270
2018-04-04 2018-04-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 13,349 616,216 2.21 1.62 21,625 998,270
2018-04-03 2018-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 638 339,585 0.19 31.29 19,963 10,625,615
2018-04-03 2018-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 638 1,382,967 0.05 31.29 19,963 43,273,037
2018-04-03 2018-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 638 1,382,967 0.05 31.29 19,963 43,273,037
2018-04-03 2018-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 638 1,382,967 0.05 31.29 19,963 43,273,037
2018-04-03 2018-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 638 1,382,967 0.05 31.29 19,963 43,273,037
2018-04-03 2018-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 638 339,585 0.19 31.29 19,963 10,625,615
2018-04-02 2018-03-29 4 INCY INCYTE CORP
Common Stock 		A - Award 228 790,006 0.03 83.33 18,999 65,831,200
2018-04-02 2018-03-29 4 INCY INCYTE CORP
Common Stock 		A - Award 228 1,249,279 0.02 83.33 18,999 104,102,419
2018-04-02 2018-03-29 4 INCY INCYTE CORP
Common Stock 		A - Award 228 790,006 0.03 83.33 18,999 65,831,200
2018-03-29 2018-03-28 4 NVTA Invitae Corp
Common Stock 		P - Purchase 999,514 7,480,182 15.42 4.50 4,497,813 33,660,819
2018-03-29 2018-03-28 4 NVTA Invitae Corp
Common Stock 		P - Purchase 111,597 845,858 15.20 4.50 502,186 3,806,361
2018-03-15 2018-03-15 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock Warrant (right to buy) 		M - Exercise -439,036 0 -100.00
2018-03-15 2018-03-15 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock Warrant (right to buy) 		M - Exercise -17,626,445 0 -100.00
2018-03-15 2018-03-15 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock Warrant (right to buy) 		M - Exercise -2,250,846 0 -100.00
2018-03-15 2018-03-15 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		M - Exercise 439,036 602,867 267.98 0.47 206,347 283,347
2018-03-15 2018-03-15 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		M - Exercise 17,626,445 34,193,251 106.40 0.47 8,284,429 16,070,828
2018-03-15 2018-03-15 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		M - Exercise 2,250,846 4,102,796 121.54 0.47 1,057,898 1,928,314
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 338,947 2.49 18.50 152,625 6,270,520
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 338,947 2.49 18.50 152,625 6,270,520
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,382,329 0.60 18.50 152,625 25,573,086
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,382,329 0.60 18.50 152,625 25,573,086
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,382,329 0.60 18.50 152,625 25,573,086
2018-03-12 2018-03-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 338,947 2.49 18.50 152,625 6,270,520
2018-02-05 2018-02-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,456,543 44,355,335 8.45 52.00 179,740,236 2,306,477,420
2018-02-05 2018-02-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 389,610 5,278,174 7.97 52.00 20,259,720 274,465,048
2018-01-22 2018-01-18 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 1,645,148 5,121,404 47.33 101.00 166,159,948 517,261,804
2018-01-22 2018-01-18 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 335,050 708,025 89.83 101.00 33,840,050 71,510,525
2018-01-19 2018-01-19 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -4,136 58,131 -6.64 7.91 -32,715 459,799
2018-01-19 2018-01-19 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -265,708 3,734,776 -6.64 7.91 -2,101,671 29,540,958
2018-01-19 2018-01-19 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -25,517 358,671 -6.64 7.91 -201,832 2,836,980
2018-01-19 2018-01-18 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -4,548 62,267 -6.81 8.12 -36,910 505,340
2018-01-19 2018-01-18 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -292,168 4,000,484 -6.81 8.12 -2,371,148 32,466,728
2018-01-19 2018-01-18 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -28,058 384,188 -6.81 8.12 -227,710 3,117,955
2018-01-19 2018-01-17 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -3,649 66,815 -5.18 8.63 -31,476 576,340
2018-01-19 2018-01-17 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -234,437 4,292,652 -5.18 8.63 -2,022,230 37,027,987
2018-01-19 2018-01-17 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		S - Sale -22,514 412,246 -5.18 8.63 -194,204 3,555,993
2018-01-04 2018-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 9,333 163,831 6.04 2.21 20,626 362,067
2018-01-04 2018-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 9,333 163,831 6.04 2.21 20,626 362,067
2018-01-04 2018-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 9,333 163,831 6.04 2.21 20,626 362,067
2018-01-03 2018-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 584 330,697 0.18 34.20 19,973 11,309,837
2018-01-03 2018-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 584 330,697 0.18 34.20 19,973 11,309,837
2018-01-03 2018-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 584 1,374,079 0.04 34.20 19,973 46,993,502
2018-01-03 2018-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 584 1,374,079 0.04 34.20 19,973 46,993,502
2018-01-03 2018-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 584 1,374,079 0.04 34.20 19,973 46,993,502
2018-01-03 2018-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 584 330,697 0.18 34.20 19,973 11,309,837
2018-01-03 2017-12-29 4 INCY INCYTE CORP
Common Stock 		A - Award 200 789,778 0.03 94.71 18,942 74,799,874
2018-01-03 2017-12-29 4 INCY INCYTE CORP
Common Stock 		A - Award 200 789,778 0.03 94.71 18,942 74,799,874
2018-01-03 2017-12-29 4 INCY INCYTE CORP
Common Stock 		A - Award 200 789,778 0.03 94.71 18,942 74,799,874
2017-11-29 2017-11-27 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock Warrant (right to buy) 		M - Exercise -39,378 0 -100.00
2017-11-29 2017-11-27 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		F - Taxes -1,941 489,977 -0.39 28.00 -54,348 13,719,356
2017-11-29 2017-11-27 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		M - Exercise 39,378 491,918 8.70 1.38 54,342 678,847
2017-11-20 2017-11-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		P - Purchase 1,618,684 1,618,684 13.00 21,041,273 21,041,273
2017-11-20 2017-11-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		P - Purchase 304,392 304,392 13.00 3,956,792 3,956,792
2017-11-13 2017-11-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -5,996 0 -100.00
2017-11-13 2017-11-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -249,801 0 -100.00
2017-11-13 2017-11-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -24,466 0 -100.00
2017-11-13 2017-11-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 5,996 35,999 19.98 7.86 47,129 282,952
2017-11-13 2017-11-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 249,801 2,372,218 11.77 7.86 1,963,436 18,645,633
2017-11-13 2017-11-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 24,466 141,244 20.95 7.86 192,303 1,110,178
2017-10-30 2017-10-26 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 7,204,652 16,557,473 77.03 1.50 10,806,978 24,836,210
2017-10-30 2017-10-26 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 795,348 1,842,617 75.94 1.50 1,193,022 2,763,926
2017-10-16 2017-10-13 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock Warrant (right to buy) 		M - Exercise -1,426,590 0 -100.00
2017-10-16 2017-10-13 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		F - Taxes -55,457 23,708,408 -0.23 35.40 -1,963,178 839,277,643
2017-10-16 2017-10-13 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		M - Exercise 1,426,590 23,763,865 6.39 1.38 1,968,694 32,794,134
2017-10-16 2017-10-13 4 BGNE BeiGene, Ltd.
American Depositary Shares 		J - Other 7,102 7,102
2017-10-16 2017-10-13 4 BGNE BeiGene, Ltd.
American Depositary Shares 		J - Other 7,102 7,102
2017-10-16 2017-10-13 4 BGNE BeiGene, Ltd.
American Depositary Shares 		J - Other -49,200 0 -100.00
2017-10-06 2017-10-05 4 RYTM RHYTHM PHARMACEUTICALS, INC.
Series A Convertible Prefered 		C - Conversion -9,913,242 0 -100.00
2017-10-06 2017-10-05 4 RYTM RHYTHM PHARMACEUTICALS, INC.
Series A Convertible Prefered 		C - Conversion -760,829 0 -100.00
2017-10-06 2017-10-05 4 RYTM RHYTHM PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 797,191 1,878,242 73.74 17.00 13,552,247 31,930,114
2017-10-06 2017-10-05 4 RYTM RHYTHM PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 87,809 170,778 105.83 17.00 1,492,753 2,903,226
2017-10-06 2017-10-05 4 RYTM RHYTHM PHARMACEUTICALS, INC.
Common Stock 		C - Conversion 1,081,051 1,081,051
2017-10-06 2017-10-05 4 RYTM RHYTHM PHARMACEUTICALS, INC.
Common Stock 		C - Conversion 82,969 82,969
2017-10-04 2017-10-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 9,045 154,498 6.22 2.28 20,623 352,255
2017-10-04 2017-10-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 9,045 154,498 6.22 2.28 20,623 352,255
2017-10-04 2017-10-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 9,045 154,498 6.22 2.28 20,623 352,255
2017-10-03 2017-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 622 330,113 0.19 32.09 19,960 10,593,326
2017-10-03 2017-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 622 330,113 0.19 32.09 19,960 10,593,326
2017-10-03 2017-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 622 1,373,495 0.05 32.09 19,960 44,075,455
2017-10-03 2017-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 622 1,373,495 0.05 32.09 19,960 44,075,455
2017-10-03 2017-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 622 1,373,495 0.05 32.09 19,960 44,075,455
2017-10-03 2017-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 622 330,113 0.19 32.09 19,960 10,593,326
2017-10-03 2017-09-29 4 INCY INCYTE CORP
Common Stock 		A - Award 162 789,578 0.02 116.74 18,912 92,175,336
2017-10-03 2017-09-29 4 INCY INCYTE CORP
Common Stock 		A - Award 162 789,578 0.02 116.74 18,912 92,175,336
2017-10-03 2017-09-29 4 INCY INCYTE CORP
Common Stock 		A - Award 162 789,578 0.02 116.74 18,912 92,175,336
2017-09-08 2017-09-08 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,029 789,416 0.26 132.00 267,828 104,202,912
2017-09-08 2017-09-08 4 INCY INCYTE CORP
Common Stock 		P - Purchase 85,402 29,247,347 0.29 132.00 11,273,064 3,860,649,804
2017-09-08 2017-09-08 4 INCY INCYTE CORP
Common Stock 		P - Purchase 12,569 4,386,818 0.29 132.00 1,659,108 579,059,976
2017-08-14 2017-08-11 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 158,279 3,476,256 4.77 71.00 11,237,809 246,814,176
2017-08-14 2017-08-11 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 17,777 372,975 5.00 71.00 1,262,167 26,481,225
2017-08-02 2017-07-31 4 NVTA Invitae Corp
Series A Convertible Preferred 		P - Purchase 3,109,063 3,109,063 8.50 26,427,036 26,427,036
2017-08-02 2017-07-31 4 NVTA Invitae Corp
Series A Convertible Preferred 		P - Purchase 349,760 349,760 8.50 2,972,960 2,972,960
2017-07-06 2017-07-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 11,787 145,453 8.82 1.75 20,627 254,543
2017-07-06 2017-07-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 11,787 145,453 8.82 1.75 20,627 254,543
2017-07-06 2017-07-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 11,787 145,453 8.82 1.75 20,627 254,543
2017-07-05 2017-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 614 1,372,873 0.04 32.55 19,986 44,687,016
2017-07-05 2017-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 614 1,372,873 0.04 32.55 19,986 44,687,016
2017-07-05 2017-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 614 1,372,873 0.04 32.55 19,986 44,687,016
2017-07-05 2017-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 614 1,372,873 0.04 32.55 19,986 44,687,016
2017-07-05 2017-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 614 1,372,873 0.04 32.55 19,986 44,687,016
2017-07-05 2017-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 614 329,491 0.19 32.55 19,986 10,724,932
2017-07-05 2017-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 150 1,246,660 0.01 125.91 18,886 156,966,961
2017-07-05 2017-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 150 1,246,660 0.01 125.91 18,886 156,966,961
2017-07-05 2017-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 150 787,387 0.02 125.91 18,886 99,139,897
2017-06-20 2017-06-16 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		A - Award 20,000 20,000
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 22,560 7,317,906 0.31 117.95 2,660,914 863,134,572
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,564 647,367 0.40 117.95 302,419 76,355,837
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 197,126 7,295,346 2.78 117.51 23,163,488 857,246,927
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 22,399 644,803 3.60 117.51 2,632,017 75,768,221
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 32,172 7,098,220 0.46 117.22 3,771,228 832,059,027
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,656 622,404 0.59 117.22 428,559 72,958,695
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 65,264 7,066,048 0.93 117.01 7,636,802 826,826,541
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 7,416 618,748 1.21 117.01 867,776 72,402,178
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 898 7,000,784 0.01 116.96 105,030 818,811,697
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 102 611,332 0.02 116.96 11,930 71,501,391
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 31,974 6,999,886 0.46 116.71 3,731,542 816,925,196
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,634 611,230 0.60 116.71 424,108 71,333,903
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 12,726 6,967,912 0.18 116.37 1,480,897 810,840,590
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,446 607,596 0.24 116.37 168,268 70,704,610
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 385,774 6,955,186 5.87 116.37 44,891,517 809,356,911
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 43,835 606,150 7.80 116.37 5,100,965 70,536,100
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,976 6,569,412 0.03 116.18 229,562 763,202,753
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 224 562,315 0.04 116.18 26,023 65,327,058
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 169,897 6,567,436 2.66 115.77 19,668,568 760,296,304
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 19,305 562,091 3.56 115.77 2,234,894 65,071,926
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 207,814 6,397,539 3.36 115.71 24,046,636 740,273,952
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 23,614 542,786 4.55 115.71 2,732,430 62,807,016
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 18,678 6,189,725 0.30 115.06 2,149,048 712,175,522
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,122 519,172 0.41 115.06 244,152 59,734,736
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 64,455 6,171,047 1.06 114.33 7,369,301 705,551,231
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 7,324 517,050 1.44 114.33 837,371 59,115,619
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 160,000 980,146 19.51 117.71 18,832,960 115,369,065
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 103,200 820,146 14.39 117.63 12,139,416 96,473,774
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 32,008 716,946 4.67 117.60 3,764,067 84,311,201
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 300 684,938 0.04 116.75 35,025 79,966,512
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,747 7,645,906 0.05 116.75 437,462 892,659,526
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 426 684,638 0.06 116.75 49,736 79,931,486
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 44,898 7,642,159 0.59 117.50 5,275,484 897,948,333
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 5,102 684,212 0.75 117.50 599,481 80,394,431
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 5,373 7,597,261 0.07 117.21 629,790 890,504,591
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 611 679,110 0.09 117.21 71,618 79,601,132
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 217,305 7,591,888 2.95 117.05 25,434,638 888,598,604
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 24,692 678,499 3.78 117.05 2,890,095 79,415,458
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 8,950 7,374,583 0.12 116.95 1,046,720 862,471,494
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,017 653,807 0.16 116.95 118,940 76,463,971
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 39,473 7,365,633 0.54 116.65 4,604,506 859,197,407
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 4,485 652,790 0.69 116.65 523,173 76,147,627
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 4,310 7,326,160 0.06 116.54 502,277 853,773,836
2017-06-16 2017-06-15 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 490 648,305 0.08 116.54 57,103 75,551,974
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,944 7,321,850 0.05 118.00 465,392 863,978,300
2017-06-16 2017-06-14 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		P - Purchase 448 647,815 0.07 118.00 52,864 76,442,170
2017-06-14 2017-06-13 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 30,000 30,000
2017-06-09 2017-06-07 4/A IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 100,000 100,000
2017-06-08 2017-06-07 4 IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 100,000 100,000
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 328,877 2.57 18.13 149,572 5,962,540
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,372,259 0.60 18.13 149,572 24,879,056
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,372,259 0.60 18.13 149,572 24,879,056
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,372,259 0.60 18.13 149,572 24,879,056
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 1,372,259 0.60 18.13 149,572 24,879,056
2017-06-01 2017-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 328,877 2.57 18.13 149,572 5,962,540
2017-05-31 2017-05-26 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 15,000 15,000
2017-05-23 2017-05-19 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2017-05-23 2017-05-19 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2017-05-23 2017-05-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 40,898,792 0.01 66.60 246,420 2,723,859,547
2017-05-23 2017-05-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 40,898,792 0.01 66.60 246,420 2,723,859,547
2017-05-17 2017-05-15 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2017-05-17 2017-05-15 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2017-05-17 2017-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 40,895,092 0.02 10.20 102,000 417,129,938
2017-05-17 2017-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 40,895,092 0.02 10.20 102,000 417,129,938
2017-05-12 2017-05-10 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 2,030 6,559,338 0.03
2017-05-12 2017-05-10 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 2,030 6,106,592 0.03
2017-05-09 2017-05-08 4 AQXP AQUINOX PHARMACEUTICALS, INC
Non-Qualified Stock Option (right to buy) 		A - Award 36,000 36,000
2017-04-28 2017-04-27 4 INCY INCYTE CORP
Non-Qualified Stock Options (right 		M - Exercise -20,000 0 -100.00
2017-04-28 2017-04-27 4 INCY INCYTE CORP
Non-Qualified Stock Options (right 		M - Exercise -20,000 0 -100.00
2017-04-28 2017-04-27 4 INCY INCYTE CORP
Non-Qualified Stock Options (right 		M - Exercise -20,000 0 -100.00
2017-04-28 2017-04-27 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 787,237 2.61 7.26 145,200 5,715,341
2017-04-28 2017-04-27 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 787,237 2.61 7.26 145,200 5,715,341
2017-04-28 2017-04-27 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 787,237 2.61 7.26 145,200 5,715,341
2017-04-21 2017-04-19 4 BGNE BeiGene, Ltd.
Share Option (right to buy) 		A - Award 399,984 399,984
2017-04-05 2017-04-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,487 133,666 6.78 2.43 20,623 324,808
2017-04-05 2017-04-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,487 133,666 6.78 2.43 20,623 324,808
2017-04-05 2017-04-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,487 133,666 6.78 2.43 20,623 324,808
2017-04-04 2017-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 142 767,237 0.02 133.67 18,981 102,556,570
2017-04-04 2017-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 142 1,226,510 0.01 133.67 18,981 163,947,592
2017-04-04 2017-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 142 767,237 0.02 133.67 18,981 102,556,570
2017-04-04 2017-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 634 320,627 0.20 31.49 19,965 10,096,544
2017-04-04 2017-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 634 1,364,009 0.05 31.49 19,965 42,952,643
2017-04-04 2017-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 634 1,364,009 0.05 31.49 19,965 42,952,643
2017-04-04 2017-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 634 1,364,009 0.05 31.49 19,965 42,952,643
2017-04-04 2017-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 634 1,364,009 0.05 31.49 19,965 42,952,643
2017-04-04 2017-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 634 320,627 0.20 31.49 19,965 10,096,544
2017-03-28 2017-03-24 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		P - Purchase 151,177 4,527,089 3.45 12.00 1,814,124 54,325,068
2017-03-28 2017-03-24 4 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		P - Purchase 15,489 434,760 3.69 12.00 185,868 5,217,120
2017-02-22 2017-02-17 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		D - Sale to Issuer -6,050,000 0 -100.00
2017-02-22 2017-02-17 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		D - Sale to Issuer -5,674,000 0 -100.00
2017-02-22 2017-02-17 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		D - Sale to Issuer -243,450,000 0 -100.00
2017-02-22 2017-02-17 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		D - Sale to Issuer -228,326,000 0 -100.00
2017-02-22 2017-02-17 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		D - Sale to Issuer -25,000,000 0 -100.00
2017-02-22 2017-02-17 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		D - Sale to Issuer -25,000,000 0 -100.00
2017-02-22 2017-02-17 4 INCY INCYTE CORP
Common Stock 		A - Award 121,672 767,095 18.85
2017-02-22 2017-02-17 4 INCY INCYTE CORP
Common Stock 		A - Award 111,514 645,423 20.89
2017-02-22 2017-02-17 4 INCY INCYTE CORP
Common Stock 		A - Award 4,896,067 29,141,653 20.19
2017-02-22 2017-02-17 4 INCY INCYTE CORP
Common Stock 		A - Award 4,487,412 24,245,586 22.71
2017-02-22 2017-02-17 4 INCY INCYTE CORP
Common Stock 		A - Award 502,779 4,353,957 13.06
2017-02-22 2017-02-17 4 INCY INCYTE CORP
Common Stock 		A - Award 491,338 3,851,178 14.62
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 32,051 9,764,459 0.33 17.76 569,226 173,416,792
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,389 1,169,695 0.29 17.76 60,189 20,773,783
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 235,169 9,732,408 2.48 17.60 4,138,880 171,286,488
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 24,871 1,166,306 2.18 17.60 437,720 20,526,519
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 35,360 9,497,239 0.37 16.31 576,555 154,855,331
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,739 1,141,435 0.33 16.31 60,966 18,611,440
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,006 9,461,879 0.05 15.62 78,207 147,819,151
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 529 1,137,696 0.05 15.62 8,264 17,773,770
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 15,148 9,456,873 0.16 15.13 229,189 143,082,488
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,602 1,137,167 0.14 15.13 24,238 17,205,337
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 9,143 9,441,725 0.10 16.20 148,089 152,927,620
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 967 1,135,565 0.09 16.20 15,662 18,392,746
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 8,671 9,432,582 0.09 15.35 133,078 144,766,552
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 917 1,134,598 0.08 15.35 14,074 17,413,243
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,442 9,423,911 0.03 16.85 41,156 158,823,999
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 258 1,133,681 0.02 16.85 4,348 19,106,266
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 11,305 9,421,469 0.12 15.32 173,204 144,346,327
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,195 1,133,423 0.11 15.32 18,309 17,365,174
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,697 9,410,164 0.06 16.74 95,365 157,521,440
2017-01-09 2017-01-09 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 603 1,132,228 0.05 16.74 10,094 18,952,931
2017-01-05 2017-01-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 14,169 125,179 12.76 1.50 21,254 187,768
2017-01-05 2017-01-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 14,169 125,179 12.76 1.50 21,254 187,768
2017-01-05 2017-01-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 14,169 125,179 12.76 1.50 21,254 187,768
2017-01-04 2016-12-30 4 INCY INCYTE CORP
Common Stock 		A - Award 189 993,182 0.02 100.27 18,951 99,586,359
2017-01-04 2016-12-30 4 INCY INCYTE CORP
Common Stock 		A - Award 189 993,182 0.02 100.27 18,951 99,586,359
2017-01-04 2016-12-30 4 INCY INCYTE CORP
Common Stock 		A - Award 189 533,909 0.04 100.27 18,951 53,535,055
2017-01-04 2017-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 680 14,045,614 0.00 29.39 19,985 412,800,595
2017-01-04 2017-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 680 14,045,614 0.00 29.39 19,985 412,800,595
2017-01-04 2017-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 680 14,045,614 0.00 29.39 19,985 412,800,595
2017-01-04 2017-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 680 14,045,614 0.00 29.39 19,985 412,800,595
2017-01-04 2017-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 680 1,363,375 0.05 29.39 19,985 40,069,591
2017-01-04 2017-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 680 319,993 0.21 29.39 19,985 9,404,594
2016-11-21 2016-11-18 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 1,594,671 3,317,977 92.54 32.00 51,029,472 106,175,264
2016-11-21 2016-11-18 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 165,824 355,198 87.56 32.00 5,306,368 11,366,336
2016-11-18 2016-11-17 4 NVTA Invitae Corp
Common Stock 		P - Purchase 664,259 6,480,668 11.42 6.00 3,985,554 38,884,008
2016-11-18 2016-11-17 4 NVTA Invitae Corp
Common Stock 		P - Purchase 69,074 734,261 10.38 6.00 414,444 4,405,566
2016-11-09 2016-11-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 294,178 40,885,092 0.72 59.46 17,493,177 2,431,215,642
2016-11-09 2016-11-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 32,122 4,874,864 0.66 59.46 1,910,122 289,881,838
2016-11-09 2016-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 50,667 40,590,914 0.12 58.74 2,976,321 2,384,423,943
2016-11-09 2016-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,533 4,842,742 0.11 58.74 325,024 284,476,225
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 18,616 40,540,247 0.05 55.99 1,042,351 2,269,937,618
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,039 4,837,209 0.04 55.99 114,168 270,845,974
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 16,854 40,521,631 0.04 56.42 950,861 2,286,129,117
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,846 4,835,170 0.04 56.42 104,147 272,788,203
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 143,016 40,504,777 0.35 56.48 8,078,001 2,287,839,420
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 15,662 4,833,324 0.33 56.48 884,640 273,001,606
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 361 40,361,761 0.00 56.49 20,393 2,280,035,879
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 39 4,817,662 0.00 56.49 2,203 272,149,726
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 456 40,361,400 0.00 56.55 25,788 2,282,558,254
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 50 4,817,623 0.00 56.55 2,828 272,451,034
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 341,438 40,360,944 0.85 56.91 19,430,383 2,296,840,421
2016-11-03 2016-11-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 37,392 4,817,573 0.78 56.91 2,127,885 274,156,035
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 95,280 40,019,506 0.24 55.84 5,320,673 2,234,789,264
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,434 4,780,181 0.22 55.84 582,661 266,937,257
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,335 39,924,226 0.01 55.87 186,336 2,230,686,279
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 365 4,769,747 0.01 55.87 20,394 266,500,074
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,289 39,920,891 0.02 56.12 352,915 2,240,208,704
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 689 4,769,382 0.01 56.12 38,664 267,639,594
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 26,381 39,914,602 0.07 56.13 1,480,758 2,240,394,636
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,889 4,768,693 0.06 56.13 162,159 267,665,307
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 289,278 39,888,221 0.73 56.26 16,274,202 2,244,031,537
2016-11-03 2016-11-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 31,679 4,765,804 0.67 56.26 1,782,197 268,114,601
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,884 39,598,943 0.01 51.83 149,479 2,052,425,095
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 316 4,734,125 0.01 51.83 16,378 245,371,119
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,434 39,596,059 0.01 53.33 129,815 2,111,812,251
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 266 4,733,809 0.01 53.33 14,187 252,472,496
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 32,717 39,593,625 0.08 53.66 1,755,578 2,124,574,121
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,583 4,733,543 0.08 53.66 192,262 253,999,551
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 40,332 39,560,908 0.10 54.37 2,192,976 2,151,049,207
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,417 4,729,960 0.09 54.37 240,166 257,182,588
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 924 39,520,576 0.00 54.51 50,365 2,154,183,605
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 101 4,725,543 0.00 54.51 5,505 257,579,425
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,803 39,519,652 0.00 54.61 98,455 2,158,021,973
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 197 4,725,442 0.00 54.61 10,757 258,038,903
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 85,353 39,517,849 0.22 54.93 4,688,039 2,170,529,712
2016-11-03 2016-11-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,347 4,725,245 0.20 54.93 513,387 259,535,499
2016-10-11 2016-10-07 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 2,928,596 9,309,333 45.90 2.00 5,857,192 18,618,666
2016-10-11 2016-10-07 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 321,404 1,003,781 47.10 2.00 642,808 2,007,562
2016-10-05 2016-10-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,299 111,010 8.08 2.56 21,245 284,186
2016-10-05 2016-10-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,299 111,010 8.08 2.56 21,245 284,186
2016-10-05 2016-10-03 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,299 111,010 8.08 2.56 21,245 284,186
2016-10-04 2016-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 201 992,993 0.02 94.29 18,952 93,629,310
2016-10-04 2016-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 201 992,993 0.02 94.29 18,952 93,629,310
2016-10-04 2016-09-30 4 INCY INCYTE CORP
Common Stock 		A - Award 201 533,720 0.04 94.29 18,952 50,324,459
2016-10-04 2016-09-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 690 1,362,695 0.05 28.92 19,955 39,409,139
2016-10-04 2016-09-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 690 1,362,695 0.05 28.92 19,955 39,409,139
2016-10-04 2016-09-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 690 1,362,695 0.05 28.92 19,955 39,409,139
2016-10-04 2016-09-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 690 1,362,695 0.05 28.92 19,955 39,409,139
2016-10-04 2016-09-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 690 1,362,695 0.05 28.92 19,955 39,409,139
2016-10-04 2016-09-30 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 690 319,313 0.22 28.92 19,955 9,234,532
2016-09-21 2016-09-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 12,550 1,131,625 1.12 13.15 165,029 14,880,529
2016-09-21 2016-09-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,476,348 9,404,467 35.74 12.25 30,335,263 115,204,721
2016-09-21 2016-09-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 294,707 1,119,075 35.75 12.25 3,610,161 13,708,669
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 24,339 39,432,496 0.06 51.55 1,254,571 2,032,575,609
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,730 4,715,898 0.06 51.55 140,720 243,084,264
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 58,541 39,408,157 0.15 51.41 3,009,341 2,025,803,896
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,565 4,713,168 0.14 51.41 337,478 242,283,700
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 899 39,349,616 0.00 50.64 45,523 1,992,546,505
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 101 4,706,603 0.00 50.64 5,114 238,328,256
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,804 39,348,717 0.06 50.42 1,099,388 1,984,017,399
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,445 4,706,502 0.05 50.42 123,280 237,308,420
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,290 39,326,913 0.05 50.41 1,073,191 1,982,398,896
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,388 4,704,057 0.05 50.41 120,375 237,123,046
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 90 39,305,623 0.00 50.00 4,500 1,965,281,150
2016-09-13 2016-09-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10 4,701,669 0.00 50.00 500 235,083,450
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 899 39,305,533 0.00 49.84 44,802 1,958,791,237
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 101 4,701,659 0.00 49.84 5,033 234,307,176
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 8,380 39,304,634 0.02 50.99 427,266 2,004,001,791
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 940 4,701,558 0.02 50.99 47,927 239,715,517
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,338 39,296,254 0.01 50.48 118,029 1,983,788,861
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 262 4,700,618 0.01 50.48 13,227 237,300,828
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 33,241 39,293,916 0.08 51.25 1,703,751 2,013,990,018
2016-09-13 2016-09-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,728 4,700,356 0.08 51.25 191,077 240,914,397
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 23,440 39,260,675 0.06 50.33 1,179,656 1,975,856,286
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,637 4,696,628 0.06 50.33 132,711 236,365,319
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 170,652 39,237,235 0.44 50.38 8,597,226 1,976,720,891
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 19,201 4,693,991 0.41 50.38 967,321 236,477,164
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 7,944 39,066,583 0.02 51.05 405,541 1,994,349,062
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 894 4,674,790 0.02 51.05 45,639 238,648,030
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 28,271 39,058,639 0.07 50.55 1,428,963 1,974,226,720
2016-09-13 2016-09-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,181 4,673,896 0.07 50.55 160,784 236,243,008
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 33,893 39,030,368 0.09 50.48 1,710,844 1,970,167,110
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,813 4,670,715 0.08 50.48 192,472 235,767,418
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 48,036 38,996,475 0.12 50.10 2,406,829 1,953,906,681
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,405 4,666,902 0.12 50.10 270,816 233,833,725
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 101,290 38,948,439 0.26 50.05 5,069,433 1,949,318,739
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 11,397 4,661,497 0.25 50.05 570,405 233,301,865
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,581 38,847,149 0.01 49.46 276,030 1,921,337,258
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 628 4,650,100 0.01 49.46 31,060 229,988,831
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 944 38,841,568 0.00 49.18 46,427 1,910,267,156
2016-09-08 2016-09-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 106 4,649,472 0.00 49.18 5,213 228,665,682
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,825 38,840,624 0.04 48.61 672,033 1,888,042,733
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,556 4,649,366 0.03 48.61 75,637 226,005,681
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 12,955 38,826,799 0.03 48.95 634,191 1,900,703,822
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,457 4,647,810 0.03 48.95 71,325 227,526,102
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 548 38,813,844 0.00 47.27 25,904 1,834,718,762
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 62 4,646,353 0.00 47.27 2,931 219,631,712
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 11,681 38,813,296 0.03 48.16 562,550 1,869,225,047
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,314 4,646,291 0.03 48.16 63,281 223,762,587
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 8,598 38,801,615 0.02 48.44 416,460 1,879,426,065
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 967 4,644,977 0.02 48.44 46,838 224,987,822
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,930 38,793,017 0.02 48.29 286,332 1,873,132,464
2016-09-08 2016-09-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 667 4,644,010 0.01 48.29 32,206 224,237,416
2016-09-08 2016-09-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 84,331 4,643,343 1.85 46.17 3,893,638 214,387,325
2016-09-08 2016-09-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,600 4,559,012 0.08 45.10 162,369 205,623,295
2016-09-08 2016-09-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 35,263 4,555,412 0.78 45.39 1,600,457 206,753,296
2016-09-08 2016-09-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 8,360 4,520,149 0.19 46.10 385,414 208,388,813
2016-09-08 2016-09-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,735 4,511,789 0.06 44.98 123,025 202,948,842
2016-09-08 2016-09-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,074 4,509,054 0.20 45.80 415,623 206,531,357
2016-08-16 2016-08-16 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -850 9,418,390 -0.01 4.29 -3,645 40,392,649
2016-08-16 2016-08-16 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -140 1,551,387 -0.01 4.29 -600 6,653,433
2016-08-16 2016-08-15 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -343,583 9,419,240 -3.52 4.83 -1,658,681 45,472,323
2016-08-16 2016-08-15 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -56,417 1,551,527 -3.51 4.83 -272,359 7,490,152
2016-08-16 2016-08-12 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -296,856 9,762,823 -2.95 5.25 -1,559,711 51,294,848
2016-08-16 2016-08-12 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -48,744 1,607,944 -2.94 5.25 -256,106 8,448,299
2016-08-16 2016-08-12 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -2,834,561 10,059,679 -21.98 5.00 -14,172,805 50,298,395
2016-08-16 2016-08-12 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		S - Sale -465,439 1,656,688 -21.93 5.00 -2,327,195 8,283,440
2016-08-15 2016-08-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 89,896 11,348,958 0.80 27.02 2,428,621 306,602,314
2016-08-15 2016-08-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 10,104 1,758,289 0.58 27.02 272,969 47,501,760
2016-08-12 2016-08-10 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,169,877 22,337,275 5.53 33.00 38,605,941 737,130,075
2016-08-12 2016-08-10 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 133,153 3,029,953 4.60 33.00 4,394,049 99,988,449
2016-07-06 2016-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 13,038 102,711 14.54 1.63 21,252 167,419
2016-07-06 2016-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 13,038 102,711 14.54 1.63 21,252 167,419
2016-07-06 2016-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 13,038 102,711 14.54 1.63 21,252 167,419
2016-07-06 2016-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 746 13,937,394 0.01 26.74 19,948 372,685,916
2016-07-06 2016-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 746 13,937,394 0.01 26.74 19,948 372,685,916
2016-07-06 2016-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 746 1,362,005 0.05 26.74 19,948 36,420,014
2016-07-06 2016-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 746 1,362,005 0.05 26.74 19,948 36,420,014
2016-07-06 2016-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 746 318,623 0.23 26.74 19,948 8,519,979
2016-07-06 2016-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 746 318,623 0.23 26.74 19,948 8,519,979
2016-07-05 2016-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 237 23,803,844 0.00 79.98 18,955 1,903,831,443
2016-07-05 2016-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 237 533,519 0.04 79.98 18,955 42,670,850
2016-07-05 2016-06-30 4 INCY INCYTE CORP
Common Stock 		A - Award 237 533,519 0.04 79.98 18,955 42,670,850
2016-06-15 2016-06-13 4 IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 70,000 70,000
2016-06-13 2016-06-10 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 26,500 26,500
2016-06-13 2016-06-10 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		A - Award 20,000 20,000
2016-06-09 2016-06-09 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -2,318 30,003 -7.17 9.56 -22,157 286,787
2016-06-09 2016-06-09 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -158,684 2,122,417 -6.96 9.56 -1,516,797 20,287,335
2016-06-09 2016-06-09 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -9,056 116,778 -7.20 9.56 -86,563 1,116,234
2016-06-09 2016-06-09 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -5,111 32,321 -13.65 9.40 -48,043 303,817
2016-06-09 2016-06-09 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -349,919 2,281,101 -13.30 9.40 -3,289,239 21,442,349
2016-06-09 2016-06-09 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -19,970 125,834 -13.70 9.40 -187,718 1,182,840
2016-06-09 2016-06-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -2,154 37,432 -5.44 9.21 -19,844 344,839
2016-06-09 2016-06-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -147,529 2,631,020 -5.31 9.21 -1,359,096 24,238,009
2016-06-09 2016-06-08 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -8,417 145,804 -5.46 9.21 -77,541 1,343,205
2016-06-09 2016-06-07 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -4,201 39,586 -9.59 9.44 -39,648 373,605
2016-06-09 2016-06-07 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -275,506 2,778,549 -9.02 9.44 -2,600,171 26,223,390
2016-06-09 2016-06-07 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		S - Sale -16,493 154,221 -9.66 9.44 -155,658 1,455,507
2016-05-31 2016-05-27 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 15,000 15,000
2016-05-24 2016-05-20 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2016-05-24 2016-05-20 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2016-05-24 2016-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 38,787,087 0.01 38.82 143,634 1,505,714,717
2016-05-24 2016-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 38,787,087 0.01 38.82 143,634 1,505,714,717
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 13,932,918 0.06 10.73 88,522 149,500,210
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 13,932,918 0.06 10.73 88,522 149,500,210
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 13,932,918 0.06 10.73 88,522 149,500,210
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 13,932,918 0.06 10.73 88,522 149,500,210
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 13,932,918 0.06 10.73 88,522 149,500,210
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		M - Exercise -8,250 0 -100.00
2016-05-19 2016-05-17 4 GHDX GENOMIC HEALTH INC
Common Stock 		M - Exercise 8,250 317,877 2.66 10.73 88,522 3,410,820
2016-05-13 2016-05-11 4 ALXN ALEXION PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 2,294 2,294
2016-05-13 2016-05-11 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 835 6,104,562 0.01
2016-05-13 2016-05-11 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 835 6,104,562 0.01
2016-05-11 2016-05-11 4 NTLA Intellia Therapeutics, Inc.
Series B Preferred Stock 		C - Conversion -1,232,130 0 -100.00
2016-05-11 2016-05-11 4 NTLA Intellia Therapeutics, Inc.
Series B Preferred Stock 		C - Conversion -101,204 0 -100.00
2016-05-11 2016-05-11 4 NTLA Intellia Therapeutics, Inc.
Common Stock 		P - Purchase 179,531 976,214 22.53 18.00 3,231,558 17,571,852
2016-05-11 2016-05-11 4 NTLA Intellia Therapeutics, Inc.
Common Stock 		P - Purchase 20,469 85,906 31.28 18.00 368,442 1,546,308
2016-05-11 2016-05-11 4 NTLA Intellia Therapeutics, Inc.
Common Stock 		C - Conversion 796,683 796,683
2016-05-11 2016-05-11 4 NTLA Intellia Therapeutics, Inc.
Common Stock 		C - Conversion 65,437 65,437
2016-04-05 2016-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 10,788 7,110,113 0.15 1.97 21,252 14,006,923
2016-04-05 2016-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 10,788 89,673 13.68 1.97 21,252 176,656
2016-04-05 2016-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 10,788 89,673 13.68 1.97 21,252 176,656
2016-04-05 2016-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 784 13,883,418 0.01 25.48 19,976 353,749,491
2016-04-05 2016-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 784 13,883,418 0.01 25.48 19,976 353,749,491
2016-04-05 2016-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 784 13,883,418 0.01 25.48 19,976 353,749,491
2016-04-05 2016-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 784 13,883,418 0.01 25.48 19,976 353,749,491
2016-04-05 2016-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 784 309,627 0.25 25.48 19,976 7,889,296
2016-04-05 2016-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 784 309,627 0.25 25.48 19,976 7,889,296
2016-04-04 2016-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 262 533,282 0.05 72.47 18,987 38,646,947
2016-04-04 2016-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 262 533,282 0.05 72.47 18,987 38,646,947
2016-04-04 2016-03-31 4 INCY INCYTE CORP
Common Stock 		A - Award 262 533,282 0.05 72.47 18,987 38,646,947
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 137 3,268,830 0.00 6.74 923 22,031,914
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -3,479 0 -100.00
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -310,003 0 -100.00
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -137 0 -100.00
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		X - Other -137 0 -100.00
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 3,479 43,787 8.63 6.74 23,448 295,124
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 310,003 3,054,055 11.30 6.74 2,089,420 20,584,331
2016-04-01 2016-03-30 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		X - Other 137 137 6.74 923 923
2016-04-01 2016-04-01 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 262,253 21,167,398 1.25 28.55 7,486,904 604,295,345
2016-04-01 2016-04-01 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 28,647 2,896,800 1.00 28.55 817,826 82,699,005
2016-04-01 2016-04-01 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 10,818 20,905,145 0.05 27.82 300,959 581,585,315
2016-04-01 2016-04-01 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,182 2,868,153 0.04 27.82 32,883 79,792,590
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 318,969 20,894,327 1.55 27.72 8,840,959 579,134,330
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 34,844 2,866,971 1.23 27.72 965,782 79,464,695
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 60,587 20,575,358 0.30 27.56 1,669,705 567,032,176
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 6,618 2,832,127 0.23 27.56 182,384 78,050,022
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 28,433 20,514,771 0.14 26.55 755,024 544,759,487
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,106 2,825,509 0.11 26.55 82,478 75,029,979
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 180,122 20,486,338 0.89 26.49 4,772,224 542,773,234
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 19,676 2,822,403 0.70 26.49 521,304 74,777,874
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 13,433 20,306,216 0.07 26.28 353,086 533,748,888
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,467 2,802,727 0.05 26.28 38,560 73,669,679
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 14,775 20,292,783 0.07 25.61 378,343 519,637,294
2016-04-01 2016-03-31 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,614 2,801,260 0.06 25.61 41,330 71,731,865
2016-04-01 2016-03-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 16,057 2,799,646 0.58 26.35 423,057 73,762,833
2016-04-01 2016-03-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 37,882 2,783,589 1.38 25.98 983,985 72,303,724
2016-04-01 2016-03-30 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 408,607 2,745,707 17.48 25.92 10,593,014 71,181,630
2016-03-21 2016-03-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 92,140 38,783,387 0.24 31.73 2,923,547 1,230,573,599
2016-03-21 2016-03-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,034 4,496,280 0.22 31.73 318,373 142,664,267
2016-03-21 2016-03-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 19,741 38,691,247 0.05 32.41 639,713 1,253,801,466
2016-03-21 2016-03-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,150 4,486,246 0.05 32.41 69,671 145,378,148
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 206,421,153 0.01 3.86 77,200 796,785,651
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 90,179 19,757,285 0.46 62.59 5,644,024 1,236,547,221
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 9,821 3,358,951 0.29 62.59 614,666 210,226,330
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 127,964 19,667,106 0.65 61.38 7,854,149 1,207,123,699
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 13,936 3,349,130 0.42 61.38 855,361 205,562,231
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 24,431 19,539,142 0.13 61.03 1,490,975 1,192,434,758
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,660 3,335,194 0.08 61.03 162,334 203,540,219
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 20,659 19,514,711 0.11 60.95 1,259,178 1,189,433,344
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,250 3,332,534 0.07 60.95 137,139 203,119,947
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 97,484 19,494,052 0.50 60.85 5,931,960 1,186,224,761
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		P - Purchase 10,616 3,330,284 0.32 60.85 645,990 202,649,780
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 533,020 3.90 3.86 77,200 2,057,457
2016-03-17 2016-03-17 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 533,020 3.90 3.86 77,200 2,057,457
2016-03-17 2016-03-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1,182 19,376,568 0.01 65.29 77,176 1,265,142,628
2016-03-17 2016-03-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 129 3,299,668 0.00 65.29 8,423 215,443,243
2016-03-17 2016-03-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 179,176 19,375,386 0.93 65.80 11,789,387 1,274,857,773
2016-03-17 2016-03-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 19,513 3,299,539 0.59 65.80 1,283,912 217,102,407
2016-03-17 2016-03-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 180,358 19,196,210 0.95 67.15 12,110,607 1,288,979,431
2016-03-17 2016-03-15 4 INCY INCYTE CORP
Common Stock 		P - Purchase 19,642 3,280,026 0.60 67.15 1,318,913 220,245,874
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 198,484 38,671,506 0.52 31.60 6,272,531 1,222,104,667
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,616 4,484,096 0.48 31.60 683,113 141,707,299
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 32,810 38,473,022 0.09 31.86 1,045,205 1,225,608,131
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,573 4,462,480 0.08 31.86 113,823 142,158,102
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 8,627 38,440,212 0.02 31.50 271,712 1,210,693,697
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 940 4,458,907 0.02 31.50 29,606 140,435,505
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 273,381 38,431,585 0.72 31.89 8,719,077 1,225,717,756
2016-03-16 2016-03-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 29,772 4,457,967 0.67 31.89 949,533 142,180,171
2016-03-16 2016-03-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 145,272 38,158,204 0.38 31.74 4,611,296 1,211,236,790
2016-03-16 2016-03-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 15,821 4,428,195 0.36 31.74 502,198 140,561,980
2016-03-16 2016-03-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 63,560 38,012,932 0.17 31.50 2,002,401 1,197,563,211
2016-03-16 2016-03-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,922 4,412,374 0.16 31.50 218,071 139,007,872
2016-03-16 2016-03-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 387,336 37,949,372 1.03 32.31 12,514,051 1,226,068,311
2016-03-16 2016-03-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 42,182 4,405,452 0.97 32.31 1,362,816 142,331,343
2016-03-16 2016-03-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 107,260 37,562,036 0.29 33.77 3,622,063 1,268,432,394
2016-03-16 2016-03-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 11,681 4,363,270 0.27 33.77 394,456 147,343,265
2016-03-16 2016-03-16 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 128,975 6,928,119 1.90 8.16 1,051,920 56,505,739
2016-03-16 2016-03-16 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 14,046 824,368 1.73 8.16 114,559 6,723,545
2016-03-16 2016-03-16 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 185,413 6,799,144 2.80 7.91 1,466,320 53,770,350
2016-03-16 2016-03-16 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 20,192 810,322 2.56 7.91 159,686 6,408,351
2016-03-16 2016-03-16 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 11,840 6,613,731 0.18 7.70 91,160 50,921,099
2016-03-16 2016-03-16 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,289 790,130 0.16 7.70 9,924 6,083,448
2016-03-16 2016-03-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 68,132 6,601,891 1.04 8.03 546,807 52,984,797
2016-03-16 2016-03-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 7,420 788,841 0.95 8.03 59,551 6,331,001
2016-03-16 2016-03-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 30,986 6,533,759 0.48 7.88 244,126 51,476,874
2016-03-16 2016-03-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,374 781,421 0.43 7.88 26,582 6,156,503
2016-03-11 2016-03-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,874 37,454,776 0.01 32.34 157,646 1,211,448,511
2016-03-11 2016-03-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 547 4,351,589 0.01 32.34 17,692 140,749,100
2016-03-11 2016-03-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 147,831 37,449,902 0.40 33.15 4,900,997 1,241,565,366
2016-03-11 2016-03-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 16,608 4,351,042 0.38 33.15 550,600 144,248,790
2016-03-11 2016-03-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 23,289 37,302,071 0.06 32.96 767,582 1,229,438,958
2016-03-11 2016-03-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,616 4,334,434 0.06 32.96 86,221 142,858,610
2016-03-11 2016-03-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 95,682 37,278,782 0.26 32.41 3,100,652 1,208,048,754
2016-03-11 2016-03-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,749 4,331,818 0.25 32.41 348,330 140,376,028
2016-03-11 2016-03-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 165,237 37,183,100 0.45 32.30 5,337,915 1,201,185,172
2016-03-11 2016-03-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 18,563 4,321,069 0.43 32.30 599,670 139,590,406
2016-03-11 2016-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 36,589 37,017,863 0.10 31.15 1,139,842 1,153,202,679
2016-03-11 2016-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,111 4,302,506 0.10 31.15 128,068 134,034,248
2016-03-11 2016-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 97,272 36,981,274 0.26 32.12 3,124,484 1,187,879,200
2016-03-11 2016-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,927 4,298,395 0.25 32.12 350,987 138,069,176
2016-03-11 2016-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 53,734 36,884,002 0.15 32.47 1,744,598 1,197,523,958
2016-03-11 2016-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,037 4,287,468 0.14 32.47 196,005 139,202,510
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 286,671,473 0.00 4.18 41,800 1,198,286,757
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 88,732 36,830,268 0.24
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,968 4,281,431 0.23
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 48,996 36,741,536 0.13
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,504 4,271,463 0.13
2016-03-08 2016-03-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 36,692,540 0.03 4.18 41,800 153,374,817
2016-03-08 2016-03-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 14,157 36,682,540 0.04 33.72 477,445 1,237,118,662
2016-03-08 2016-03-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,590 4,255,959 0.04 33.72 53,623 143,532,217
2016-03-08 2016-03-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 40,921 36,668,383 0.11 33.68 1,378,043 1,234,833,465
2016-03-08 2016-03-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,597 4,254,369 0.11 33.68 154,807 143,268,854
2016-03-08 2016-03-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 218,550 36,627,462 0.60 32.49 7,101,280 1,190,125,135
2016-03-08 2016-03-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 23,908 4,249,772 0.57 32.49 776,835 138,086,567
2016-03-08 2016-03-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 41,104 36,408,912 0.11 31.68 1,302,257 1,153,507,150
2016-03-08 2016-03-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,496 4,225,864 0.11 31.68 142,442 133,883,823
2016-03-02 2016-03-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 59,492 36,367,808 0.16 32.24 1,918,022 1,172,498,130
2016-03-02 2016-03-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,508 4,221,368 0.15 32.24 209,818 136,096,904
2016-03-02 2016-03-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 301,066 36,308,316 0.84 32.76 9,862,139 1,189,366,031
2016-03-02 2016-03-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 32,934 4,214,860 0.79 32.76 1,078,832 138,067,855
2016-03-02 2016-03-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,814 36,007,250 0.06 31.24 681,563 1,125,021,321
2016-03-02 2016-03-01 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,386 4,181,926 0.06 31.24 74,549 130,661,351
2016-03-02 2016-02-29 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 172,462 35,985,436 0.48 30.34 5,232,928 1,091,888,092
2016-03-02 2016-02-29 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 18,866 4,179,540 0.45 30.34 572,442 126,817,692
2016-03-02 2016-02-29 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 54,439 35,812,974 0.15 30.55 1,663,024 1,094,029,055
2016-03-02 2016-02-29 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,955 4,160,674 0.14 30.55 181,916 127,101,934
2016-02-26 2016-02-25 4 INCY INCYTE CORP
Common Stock 		P - Purchase 6,022 19,015,852 0.03 74.00 445,628 1,407,173,048
2016-02-26 2016-02-25 4 INCY INCYTE CORP
Common Stock 		P - Purchase 678 3,260,384 0.02 74.00 50,172 241,268,416
2016-02-26 2016-02-24 4 INCY INCYTE CORP
Common Stock 		P - Purchase 20,492 19,009,830 0.11 69.70 1,428,282 1,324,975,646
2016-02-26 2016-02-24 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,308 3,259,706 0.07 69.70 160,866 227,199,878
2016-02-26 2016-02-24 4 INCY INCYTE CORP
Common Stock 		P - Purchase 23,157 18,989,338 0.12 70.50 1,632,684 1,338,843,276
2016-02-26 2016-02-24 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,608 3,257,398 0.08 70.50 183,877 229,662,846
2016-02-26 2016-02-24 4 INCY INCYTE CORP
Common Stock 		P - Purchase 8,111 18,966,181 0.04 71.96 583,702 1,364,886,043
2016-02-26 2016-02-24 4 INCY INCYTE CORP
Common Stock 		P - Purchase 914 3,254,790 0.03 71.96 65,775 234,228,359
2016-02-26 2016-02-26 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 39,815 35,758,535 0.11 30.13 1,199,793 1,077,554,845
2016-02-26 2016-02-26 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,485 4,154,719 0.11 30.13 135,152 125,199,133
2016-02-26 2016-02-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 128,255 35,718,720 0.36 29.86 3,830,118 1,066,678,851
2016-02-26 2016-02-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 14,447 4,150,234 0.35 29.86 431,435 123,939,683
2016-02-26 2016-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 67,407 35,590,465 0.19 28.52 1,922,670 1,015,157,510
2016-02-26 2016-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 7,593 4,135,787 0.18 28.52 216,577 117,966,293
2016-02-26 2016-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,134 35,523,058 0.01 28.46 117,674 1,011,163,846
2016-02-26 2016-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 466 4,128,194 0.01 28.46 13,265 117,509,042
2016-02-26 2016-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 43,056 35,518,924 0.12 29.77 1,281,975 1,057,561,755
2016-02-26 2016-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,850 4,127,728 0.12 29.77 144,407 122,901,450
2016-02-22 2016-02-22 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 218,768 35,475,868 0.62 30.21 6,610,053 1,071,899,804
2016-02-22 2016-02-22 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 24,643 4,122,878 0.60 30.21 744,586 124,572,346
2016-02-22 2016-02-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 456,849 35,257,100 1.31 29.20 13,339,991 1,029,507,320
2016-02-22 2016-02-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 49,677 4,098,235 1.23 29.20 1,450,568 119,668,462
2016-02-22 2016-02-18 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 226,865 34,800,251 0.66 29.94 6,791,816 1,041,839,474
2016-02-22 2016-02-18 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 24,669 4,048,558 0.61 29.94 738,533 121,204,515
2016-02-17 2016-02-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 726,291 34,573,386 2.15 31.25 22,694,197 1,080,304,220
2016-02-17 2016-02-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 78,976 4,023,889 2.00 31.25 2,467,739 125,733,252
2016-02-17 2016-02-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 902 33,847,095 0.00 29.50 26,609 998,489,302
2016-02-17 2016-02-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 98 3,944,913 0.00 29.50 2,891 116,374,934
2016-02-17 2016-02-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 106,444 33,846,193 0.32 29.19 3,107,590 988,126,066
2016-02-17 2016-02-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 11,575 3,944,815 0.29 29.19 337,927 115,167,296
2016-02-17 2016-02-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 151,144 33,739,749 0.45 30.27 4,574,645 1,021,194,235
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 16,435 3,933,240 0.42 30.27 497,435 119,046,588
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 631 33,588,605 0.00 27.93 17,626 938,227,145
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 69 3,916,805 0.00 27.93 1,927 109,407,722
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 72,073 33,587,974 0.22 27.28 1,966,043 916,229,549
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 7,909 3,916,736 0.20 27.28 215,746 106,842,683
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 87,049 33,515,901 0.26 28.07 2,443,831 940,932,108
2016-02-17 2016-02-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,551 3,908,827 0.24 28.07 268,137 109,737,191
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 15,187 18,958,070 0.08 69.45 1,054,742 1,316,643,649
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1,651 3,253,876 0.05 69.45 114,662 225,982,664
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 8,250 18,942,883 0.04 70.86 584,597 1,342,296,478
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 897 3,252,225 0.03 70.86 63,562 230,453,314
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 67,373 18,934,633 0.36 69.54 4,684,923 1,316,659,468
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 7,326 3,251,328 0.23 69.54 509,429 226,087,920
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 124,057 18,867,260 0.66 70.21 8,710,228 1,324,698,625
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 13,490 3,244,002 0.42 70.21 947,153 227,766,246
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 397,079 18,743,203 2.16 71.10 28,233,945 1,332,718,580
2016-02-16 2016-02-16 4 INCY INCYTE CORP
Common Stock 		P - Purchase 43,178 3,230,512 1.35 71.10 3,070,133 229,702,648
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 149,927 18,346,124 0.82 67.94 10,186,595 1,246,503,545
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 16,450 3,187,334 0.52 67.94 1,117,674 216,559,265
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 38,117 18,196,197 0.21 63.98 2,438,547 1,164,107,162
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 4,183 3,170,884 0.13 63.98 267,609 202,858,255
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 168,055 18,158,080 0.93 64.87 10,902,350 1,177,981,834
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 18,441 3,166,701 0.59 64.87 1,196,336 205,435,611
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 541,340 17,990,025 3.10 65.80 35,621,958 1,183,803,012
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 59,401 3,148,260 1.92 65.80 3,908,782 207,165,897
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 49,021 17,448,685 0.28 66.68 3,268,823 1,163,514,958
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 5,379 3,088,859 0.17 66.68 358,683 205,971,605
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 72,894 17,399,664 0.42 67.68 4,933,706 1,177,666,678
2016-02-16 2016-02-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 7,999 3,083,480 0.26 67.68 541,399 208,700,102
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 6,939 17,326,770 0.04 60.85 422,220 1,054,288,905
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 761 3,075,481 0.02 60.85 46,305 187,135,023
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 57,865 17,319,831 0.34 61.73 3,572,047 1,069,165,292
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 6,349 3,074,720 0.21 61.73 391,928 189,804,618
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 136,793 17,261,966 0.80 58.13 7,952,133 1,003,482,965
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 15,010 3,068,371 0.49 58.13 872,570 178,372,384
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 114,908 17,125,173 0.68 59.01 6,780,526 1,010,527,346
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 12,609 3,053,361 0.41 59.01 744,036 180,173,642
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 65,309 17,010,265 0.39 60.40 3,944,513 1,027,380,882
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 7,166 3,040,752 0.24 60.40 432,810 183,654,427
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 113,546 16,944,956 0.67 61.40 6,971,475 1,040,383,019
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 12,459 3,033,586 0.41 61.40 764,955 186,255,507
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 289,755 16,831,410 1.75 62.56 18,126,986 1,052,967,960
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 31,795 3,021,127 1.06 62.56 1,989,086 189,000,799
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 176,647 16,541,655 1.08 63.37 11,194,368 1,048,267,836
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 19,383 2,989,332 0.65 63.37 1,228,328 189,438,154
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 235,734 16,365,008 1.46 64.46 15,195,814 1,054,916,236
2016-02-16 2016-02-11 4 INCY INCYTE CORP
Common Stock 		P - Purchase 25,869 2,969,949 0.88 64.46 1,667,560 191,447,961
2016-02-09 2016-02-05 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 45,000 12,894,240 0.35 6.33 284,656 81,565,094
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary stock warrant (right to buy) 		X - Other -56,853 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary stock warrant (right to buy) 		X - Other -2,296,890 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary stock warrant (right to buy) 		X - Other -238,850 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Series A-2 Preferred shares 		C - Conversion -26,292,961 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Series A-2 Preferred shares 		C - Conversion -1,912,167 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Series A Preferred shares 		C - Conversion -582,747 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Series A Preferred shares 		C - Conversion -44,572,171 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Series A Preferred shares 		C - Conversion -4,382,118 0 -100.00
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 1,723,306 1,723,306 24.00 41,359,344 41,359,344
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
American Depositary Shares 		P - Purchase 189,374 189,374 24.00 4,544,976 4,544,976
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		X - Other 56,853 639,600 9.76 0.68 38,376 431,730
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		X - Other 2,296,890 73,162,022 3.24 0.68 1,550,401 49,384,365
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		X - Other 238,850 6,533,135 3.79 0.68 161,224 4,409,866
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		C - Conversion 26,292,961 70,865,132 58.99
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		C - Conversion 1,912,167 6,294,285 43.64
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		C - Conversion 582,747 582,747
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		C - Conversion 44,572,171 44,572,171
2016-02-09 2016-02-08 4 BGNE BeiGene, Ltd.
Ordinary shares 		C - Conversion 4,382,118 4,382,118
2016-02-04 2016-02-04 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 24,800 12,849,240 0.19 6.65 164,915 85,444,876
2016-02-04 2016-02-03 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 91,187 12,824,440 0.72 6.29 573,311 80,629,819
2016-02-04 2016-02-02 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 91,728 12,733,253 0.73 6.52 598,360 83,061,556
2016-01-29 2016-01-28 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 25,000 12,641,525 0.20 6.88 172,015 86,981,277
2016-01-29 2016-01-27 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 63,345 12,616,525 0.50 6.98 441,971 88,028,018
2016-01-26 2016-01-26 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,581 6,502,773 0.06 11.00 39,377 71,504,492
2016-01-26 2016-01-26 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 395 778,047 0.05 11.00 4,343 8,555,405
2016-01-26 2016-01-26 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 66,345 6,499,192 1.03 10.80 716,745 70,212,721
2016-01-26 2016-01-26 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 7,318 777,652 0.95 10.80 79,059 8,401,208
2016-01-26 2016-01-25 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,522 6,432,847 0.04 11.20 28,257 72,075,548
2016-01-26 2016-01-25 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 278 770,334 0.04 11.20 3,115 8,631,053
2016-01-26 2016-01-25 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 4,503 6,430,325 0.07 10.98 49,423 70,576,032
2016-01-26 2016-01-25 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 497 770,056 0.06 10.98 5,455 8,451,750
2016-01-26 2016-01-25 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,833 6,425,822 0.04 11.23 31,822 72,178,688
2016-01-26 2016-01-25 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 312 769,559 0.04 11.23 3,505 8,644,148
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 25,650 6,422,989 0.40 10.69 274,219 68,666,891
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,810 769,247 0.37 10.69 30,041 8,223,866
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 156 6,397,339 0.00 10.60 1,654 67,811,793
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 17 766,437 0.00 10.60 180 8,124,232
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 4,021 6,397,183 0.06 10.69 42,999 68,409,556
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 440 766,420 0.06 10.69 4,705 8,195,866
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 17,221 6,393,162 0.27 10.78 185,666 68,927,237
2016-01-26 2016-01-22 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,887 765,980 0.25 10.78 20,345 8,258,337
2016-01-25 2016-01-22 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 3,200 12,553,180 0.03 7.00 22,389 87,829,579
2016-01-25 2016-01-21 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 103,600 12,549,980 0.83 7.29 755,368 91,504,414
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,734 6,375,941 0.03 8.90 15,433 56,745,875
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 190 764,093 0.02 8.90 1,691 6,800,428
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 27,996 6,374,207 0.44 8.96 250,766 57,095,047
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,067 763,903 0.40 8.96 27,472 6,842,432
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 13,789 6,346,211 0.22 8.96 123,493 56,836,031
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,511 760,836 0.20 8.96 13,532 6,813,971
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 57,453 6,332,422 0.92 9.89 567,934 62,597,258
2016-01-20 2016-01-20 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 6,294 759,325 0.84 9.89 62,217 7,506,079
2016-01-20 2016-01-19 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 14,313 6,274,969 0.23 9.15 131,017 57,439,184
2016-01-20 2016-01-19 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,568 753,031 0.21 9.15 14,353 6,893,020
2016-01-20 2016-01-19 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 10,123 6,260,656 0.16 9.21 93,282 57,691,319
2016-01-20 2016-01-19 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,109 751,463 0.15 9.21 10,219 6,924,656
2016-01-20 2016-01-19 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 45,903 6,250,533 0.74 9.08 416,602 56,727,962
2016-01-20 2016-01-19 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,029 750,354 0.67 9.08 45,642 6,809,988
2016-01-20 2016-01-20 4 BCRX BIOCRYST PHARMACEUTICALS INC
Comon Stock 		P - Purchase 1,325 12,446,380 0.01 6.94 9,197 86,396,547
2016-01-20 2016-01-20 4 BCRX BIOCRYST PHARMACEUTICALS INC
Comon Stock 		P - Purchase 51,370 12,445,055 0.41 6.87 352,974 85,512,462
2016-01-20 2016-01-19 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 92,200 12,393,685 0.75 7.12 656,750 88,281,458
2016-01-20 2016-01-15 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 25,000 12,301,485 0.20 7.49 187,332 92,178,718
2016-01-20 2016-01-15 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 175,000 12,276,485 1.45 7.45 1,303,890 91,469,634
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 47,193 6,204,630 0.77 8.56 403,930 53,106,049
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,196 745,325 0.70 8.56 44,473 6,379,311
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 4,949 6,157,437 0.08 8.95 44,308 55,126,918
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 545 740,129 0.07 8.95 4,879 6,626,301
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,279 6,152,488 0.05 8.82 28,937 54,295,091
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 361 739,584 0.05 8.82 3,186 6,526,755
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 20,851 6,149,209 0.34 8.10 168,891 49,807,978
2016-01-15 2016-01-15 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,296 739,223 0.31 8.10 18,597 5,987,632
2016-01-15 2016-01-14 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,998 6,128,358 0.05 8.08 24,213 49,495,071
2016-01-15 2016-01-14 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 330 736,927 0.04 8.08 2,665 5,951,717
2016-01-15 2016-01-14 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 12,706 6,125,360 0.21 7.91 100,517 48,457,723
2016-01-15 2016-01-14 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,399 736,597 0.19 7.91 11,067 5,827,219
2016-01-15 2016-01-14 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 90,550 6,112,654 1.50 8.17 739,947 49,950,775
2016-01-15 2016-01-14 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 9,970 735,198 1.37 8.17 81,472 6,007,817
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 47,193 6,204,630 0.77 8.56 403,930 53,106,049
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 5,196 745,325 0.70 8.56 44,473 6,379,311
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 4,949 6,157,437 0.08 8.95 44,308 55,126,918
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 545 740,129 0.07 8.95 4,879 6,626,301
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 3,279 6,152,488 0.05 8.82 28,937 54,295,091
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 361 739,584 0.05 8.82 3,186 6,526,755
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 20,851 6,149,209 0.34 8.10 168,891 49,807,978
2016-01-15 2016-01-15 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,296 739,223 0.31 8.10 18,597 5,987,632
2016-01-15 2016-01-14 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,998 6,128,358 0.05 8.08 24,213 49,495,071
2016-01-15 2016-01-14 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 330 736,927 0.04 8.08 2,665 5,951,717
2016-01-15 2016-01-14 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 12,706 6,125,360 0.21 7.91 100,517 48,457,723
2016-01-15 2016-01-14 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 1,399 736,597 0.19 7.91 11,067 5,827,219
2016-01-15 2016-01-14 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 90,550 6,112,654 1.50 8.17 739,947 49,950,775
2016-01-15 2016-01-14 4/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 9,970 735,198 1.37 8.17 81,472 6,007,817
2016-01-08 2016-01-07 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,801,161 20,278,008 9.75 29.00 52,233,669 588,062,232
2016-01-08 2016-01-07 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 785,045 2,337,100 50.58 29.00 22,766,305 67,775,900
2016-01-08 2016-01-07 4/A ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,801,161 20,278,008 9.75 29.00 52,233,669 588,062,232
2016-01-08 2016-01-07 4/A ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 785,045 2,337,100 50.58 29.00 22,766,305 67,775,900
2016-01-06 2016-01-04 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 7,082 78,885 9.86 3.00 21,246 236,655
2016-01-06 2016-01-04 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 7,082 78,885 9.86 3.00 21,246 236,655
2016-01-06 2016-01-04 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 7,082 6,348,612 0.11 3.00 21,246 19,045,836
2016-01-05 2015-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 175 513,020 0.03 108.45 18,979 55,637,019
2016-01-05 2015-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 175 513,020 0.03 108.45 18,979 55,637,019
2016-01-05 2015-12-31 4 INCY INCYTE CORP
Common Stock 		A - Award 175 666,111 0.03 108.45 18,979 72,239,738
2016-01-05 2016-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 568 308,843 0.18 35.20 19,994 10,871,274
2016-01-05 2016-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 568 308,843 0.18 35.20 19,994 10,871,274
2016-01-05 2016-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 568 482,740 0.12 35.20 19,994 16,992,448
2016-01-05 2016-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 568 11,423,179 0.00 35.20 19,994 402,095,901
2016-01-05 2016-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 568 196,132 0.29 35.20 19,994 6,903,846
2016-01-05 2016-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 568 356,791 0.16 35.20 19,994 12,559,043
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		5,284,918
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		9,241,559
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		4,936,111
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		5,284,918
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		9,241,559
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		4,936,111
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		5,284,918
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		9,241,559
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		4,936,111
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		5,284,918
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		9,241,559
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		4,936,111
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		5,284,918
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		9,241,559
2015-12-24 3 BLCM BELLICUM PHARMACEUTICALS, INC
Common Stock 		4,936,111
2015-12-15 2015-12-11 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2015-11-20 2015-11-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 150,000 33,428,852 0.45 44.00 6,600,000 1,470,869,488
2015-11-20 2015-11-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 31,647 33,278,852 0.10 43.87 1,388,259 1,459,843,401
2015-11-20 2015-11-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 57,461 33,247,205 0.17 43.93 2,524,015 1,460,406,753
2015-11-20 2015-11-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 75,612 33,189,744 0.23 43.93 3,321,363 1,457,905,971
2015-11-20 2015-11-18 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,000 33,114,132 0.01 43.00 172,000 1,423,907,676
2015-11-20 2015-11-18 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,638 33,110,132 0.03 43.84 466,321 1,451,395,880
2015-11-10 2015-11-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,400 33,099,494 0.03 44.00 413,600 1,456,377,736
2015-11-10 2015-11-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 800 33,090,094 0.00 43.00 34,400 1,422,874,042
2015-11-10 2015-11-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 407,800 33,089,294 1.25 43.71 17,823,388 1,446,207,301
2015-11-10 2015-11-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 98,700 32,681,494 0.30 44.00 4,342,800 1,437,985,736
2015-11-10 2015-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 196,490 32,582,794 0.61 41.31 8,117,179 1,346,024,545
2015-11-10 2015-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 221,434 32,386,304 0.69 42.51 9,412,318 1,376,618,715
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		16,392,657
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		26,372,015
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		16,392,657
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		26,372,015
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		16,392,657
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		26,372,015
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		16,392,657
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		26,372,015
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		14,293,989
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		16,392,657
2015-11-06 3 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		26,372,015
2015-10-05 2015-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 6,945 71,803 10.71 3.06 21,252 219,717
2015-10-05 2015-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 6,945 71,803 10.71 3.06 21,252 219,717
2015-10-05 2015-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 6,945 71,803 10.71 3.06 21,252 219,717
2015-10-05 2015-10-01 4 INCY INCYTE CORP
Common Stock 		A - Award 172 512,845 0.03 110.33 18,977 56,582,189
2015-10-05 2015-10-01 4 INCY INCYTE CORP
Common Stock 		A - Award 172 972,118 0.02 110.33 18,977 107,253,779
2015-10-05 2015-10-01 4 INCY INCYTE CORP
Common Stock 		A - Award 172 16,282,190 0.00 110.33 18,977 1,796,414,023
2015-10-05 2015-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 936 308,275 0.30 21.34 19,974 6,578,588
2015-10-05 2015-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 936 308,275 0.30 21.34 19,974 6,578,588
2015-10-05 2015-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 936 11,422,611 0.01 21.34 19,974 243,758,519
2015-10-05 2015-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 936 1,911,734 0.05 21.34 19,974 40,796,404
2015-10-05 2015-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 936 195,564 0.48 21.34 19,974 4,173,336
2015-10-05 2015-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 936 356,223 0.26 21.34 19,974 7,601,799
2015-09-18 2015-09-16 4 INCY INCYTE CORP
4.75% Convertible Senior Notes due 2015 		M - Exercise -892,000 0 -100.00
2015-09-18 2015-09-16 4 INCY INCYTE CORP
4.75% Convertible Senior Notes due 2015 		M - Exercise -31,967,000 0 -100.00
2015-09-18 2015-09-16 4 INCY INCYTE CORP
4.75% Convertible Senior Notes due 2015 		M - Exercise -7,587,000 0 -100.00
2015-09-18 2015-09-16 4 INCY INCYTE CORP
4.75% Convertible Senior Notes due 2015 		M - Exercise -65,000 0 -100.00
2015-09-18 2015-09-16 4 INCY INCYTE CORP
4.75% Convertible Senior Notes due 2015 		M - Exercise -64,000 0 -100.00
2015-09-18 2015-09-16 4 INCY INCYTE CORP
Common Stock 		M - Exercise 101,652 512,673 24.73
2015-09-18 2015-09-16 4 INCY INCYTE CORP
Common Stock 		M - Exercise 3,642,962 16,128,927 29.18
2015-09-18 2015-09-16 4 INCY INCYTE CORP
Common Stock 		M - Exercise 864,614 2,943,733 41.59
2015-09-18 2015-09-16 4 INCY INCYTE CORP
Common Stock 		M - Exercise 7,406 61,049 13.81
2015-09-18 2015-09-16 4 INCY INCYTE CORP
Common Stock 		M - Exercise 7,292 58,632 14.20
2015-09-16 2015-09-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		J - Other 137 137
2015-09-16 2015-09-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		J - Other 137 137
2015-09-16 2015-09-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock Warrants (right to buy) 		J - Other -274 0 -100.00
2015-09-16 2015-09-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 139,220 2,744,052 5.34 45.00 6,264,900 123,482,340
2015-09-16 2015-09-16 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 10,780 170,714 6.74 45.00 485,100 7,682,130
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 346,000 32,164,870 1.09 48.44 16,761,728 1,558,204,612
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 50,000 31,818,870 0.16 47.40 2,370,000 1,508,214,438
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 160,453 31,768,870 0.51 48.60 7,798,690 1,544,100,511
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 33,320 31,608,417 0.11 47.98 1,598,614 1,516,495,987
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 14,386 31,575,097 0.05 47.54 683,847 1,500,941,181
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,600 31,560,711 0.01 47.24 75,577 1,490,798,589
2015-09-15 2015-09-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 20,500 31,559,111 0.06 46.31 949,351 1,461,496,119
2015-09-15 2015-09-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,950 31,538,611 0.01 44.68 87,130 1,409,201,909
2015-09-15 2015-09-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 89,843 31,536,661 0.29 45.28 4,067,696 1,427,841,249
2015-09-15 2015-09-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 212,983 31,446,818 0.68 46.81 9,969,500 1,471,990,959
2015-09-15 2015-09-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,818 31,233,835 0.03 46.74 458,905 1,459,906,929
2015-09-15 2015-09-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,331 31,224,017 0.01 45.63 106,368 1,424,814,344
2015-09-15 2015-09-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,513 31,221,686 0.01 45.43 159,601 1,418,448,028
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,897 31,218,173 0.04 45.00 625,359 1,404,805,298
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 40,649 31,204,276 0.13 42.14 1,713,148 1,315,101,092
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 8,063 31,163,627 0.03 44.40 357,971 1,383,565,315
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 15,391 31,155,564 0.05 40.67 625,950 1,267,093,672
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 191,321 31,140,173 0.62 41.06 7,856,214 1,278,708,924
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 88,640 30,948,852 0.29 42.44 3,761,802 1,313,441,425
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 183,073 30,860,212 0.60 43.28 7,923,253 1,335,605,287
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 274,814 30,677,139 0.90 44.63 12,265,553 1,369,188,203
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,100 30,402,325 0.01 40.55 125,706 1,232,823,399
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 11,300 30,399,225 0.04 41.13 464,823 1,250,466,041
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 43,612 30,387,925 0.14 43.60 1,901,322 1,324,801,095
2015-09-15 2015-09-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,338,927 30,344,313 12.36 41.00 136,896,007 1,244,116,833
2015-09-11 2015-09-10 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 2,213,469 6,022,104 58.12 15.50 34,308,770 93,342,612
2015-09-11 2015-09-10 4 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		P - Purchase 266,563 725,228 58.12 15.50 4,131,726 11,241,034
2015-08-27 3 NVTA Invitae Corp
Common Stock 		7,220,154
2015-08-27 3 NVTA Invitae Corp
Common Stock 		12,371,376
2015-08-27 3 NVTA Invitae Corp
Common Stock 		6,628,338
2015-08-27 3 NVTA Invitae Corp
Common Stock 		7,220,154
2015-08-27 3 NVTA Invitae Corp
Common Stock 		12,371,376
2015-08-27 3 NVTA Invitae Corp
Common Stock 		6,628,338
2015-08-27 3 NVTA Invitae Corp
Common Stock 		7,220,154
2015-08-27 3 NVTA Invitae Corp
Common Stock 		12,371,376
2015-08-27 3 NVTA Invitae Corp
Common Stock 		6,628,338
2015-08-27 3 NVTA Invitae Corp
Common Stock 		7,220,154
2015-08-27 3 NVTA Invitae Corp
Common Stock 		12,371,376
2015-08-27 3 NVTA Invitae Corp
Common Stock 		6,628,338
2015-08-27 3 NVTA Invitae Corp
Common Stock 		7,220,154
2015-08-27 3 NVTA Invitae Corp
Common Stock 		12,371,376
2015-08-27 3 NVTA Invitae Corp
Common Stock 		6,628,338
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		4,725,965
2015-08-10 3 AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		8,075,935
2015-08-10 3/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		2,260
2015-08-10 3/A AQXP AQUINOX PHARMACEUTICALS, INC
Common Stock 		2,260
2015-07-24 2015-07-22 4 ALXN ALEXION PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 2,329 2,329
2015-07-24 2015-07-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 696 6,103,727 0.01
2015-07-24 2015-07-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 696 6,103,727 0.01
2015-07-23 2015-07-22 4 XOMA XOMA Corp
Common Stock 		S - Sale -229,436 90,538 -71.70 1.09 -250,659 98,913
2015-07-23 2015-07-22 4 XOMA XOMA Corp
Common Stock 		S - Sale -9,411,311 3,153,539 -74.90 1.09 -10,281,857 3,445,241
2015-07-23 2015-07-22 4 XOMA XOMA Corp
Common Stock 		S - Sale -1,359,253 467,436 -74.41 1.09 -1,484,984 510,674
2015-07-06 2015-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 730 307,339 0.24 27.34 19,958 8,402,648
2015-07-06 2015-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 730 1,350,721 0.05 27.34 19,958 36,928,712
2015-07-06 2015-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 730 481,236 0.15 27.34 19,958 13,156,992
2015-07-06 2015-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 730 11,421,675 0.01 27.34 19,958 312,268,594
2015-07-06 2015-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 730 194,628 0.38 27.34 19,958 5,321,130
2015-07-06 2015-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 730 355,287 0.21 27.34 19,958 9,713,547
2015-07-06 2015-07-01 4 INCY INCYTE CORP
Common Stock 		A - Award 182 826,200 0.02 104.21 18,966 86,098,302
2015-07-06 2015-07-01 4 INCY INCYTE CORP
Common Stock 		A - Award 182 411,021 0.04 104.21 18,966 42,832,498
2015-07-06 2015-07-01 4 INCY INCYTE CORP
Common Stock 		A - Award 182 549,414 0.03 104.21 18,966 57,254,433
2015-07-06 2015-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 5,260 64,858 8.83 3.66 19,252 237,380
2015-07-06 2015-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 5,260 64,858 8.83 3.66 19,252 237,380
2015-07-06 2015-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 5,260 64,858 8.83 3.66 19,252 237,380
2015-06-24 2015-06-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 6,103,033 6,103,033
2015-06-24 2015-06-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 506,166 506,166
2015-06-24 2015-06-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 94,412 94,412
2015-06-24 2015-06-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 66,154 66,154
2015-06-24 2015-06-22 4 ALXN ALEXION PHARMACEUTICALS INC
Common Stock 		A - Award 65,811 65,811
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,500 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,500 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,500 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -3,000 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -3,000 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -15,000 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -7,500 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -7,500 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -7,500 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,750 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,750 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -2,750 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -9,184,771 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -12,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -12,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -12,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -12,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -12,250 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -680,187 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -143,462 0 -100.00
2015-06-23 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Comon Stock 		D - Sale to Issuer -200,526 0 -100.00
2015-06-23 2014-06-04 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -7,500 0 -100.00
2015-06-23 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -7,500 0 -100.00
2015-06-23 2012-06-27 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -7,500 0 -100.00
2015-06-23 2011-12-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		D - Sale to Issuer -15,000 0 -100.00
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other 21,196 100,003 26.90
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other -211,614 12,250 -94.53
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other 497 78,807 0.63
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other -100,490 12,250 -89.13
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other 40,449 78,310 106.84
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other -1,068,128 680,187 -61.09
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other 5,543 37,861 17.15
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other -55,479 12,250 -81.91
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other 12,500 32,318 63.07
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other -165,213 12,250 -93.10
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other 19,318 19,818 3,863.60
2015-06-22 2015-06-22 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		J - Other -206,800 12,250 -94.41
2015-06-17 2015-06-15 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 12,500 12,500
2015-06-16 2015-06-12 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		A - Award 20,000 20,000
2015-06-10 2015-06-08 4 IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 70,000 70,000
2015-05-27 2015-05-22 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 15,000 15,000
2015-05-21 2015-05-21 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 198,802 27,005,386 0.74 43.27 8,602,242 1,168,533,854
2015-05-21 2015-05-21 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 57,202 26,816,266 0.21 43.29 2,476,343 1,160,908,335
2015-05-21 2015-05-21 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 16,300 26,759,064 0.06 43.67 711,775 1,168,493,400
2015-05-21 2015-05-21 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 90,155 26,742,764 0.34 43.62 3,932,723 1,166,567,503
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 150,000 26,652,609 0.57 42.93 6,439,500 1,144,196,504
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 9,200 26,492,927 0.03 40.95 376,718 1,084,821,778
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 52,381 26,483,727 0.20 41.54 2,176,038 1,100,200,229
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 139,683 26,431,346 0.53 42.68 5,961,908 1,128,134,781
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 13,352 26,291,663 0.05 42.97 573,749 1,129,779,051
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 2,300 26,278,311 0.01 42.15 96,949 1,107,675,482
2015-05-21 2015-05-20 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 7,382 26,276,011 0.03 41.24 304,410 1,083,538,610
2015-05-21 2015-05-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,500 26,268,629 0.02 41.07 184,815 1,078,852,593
2015-05-21 2015-05-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 89,100 26,264,129 0.34 40.57 3,614,475 1,065,443,789
2015-05-21 2015-05-19 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 120,529 26,175,029 0.46 41.09 4,951,958 1,075,406,301
2015-05-18 2015-05-15 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2015-05-18 2015-05-15 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 9,260 9,260
2015-05-18 2015-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 26,054,500 0.01 39.94 147,778 1,040,616,730
2015-05-18 2015-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,700 26,054,500 0.01 39.94 147,778 1,040,616,730
2015-05-12 2015-05-11 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2015-05-12 2015-05-11 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2015-05-12 2015-05-11 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -20,000 0 -100.00
2015-05-12 2015-05-11 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 410,839 5.12 7.68 153,600 3,155,244
2015-05-12 2015-05-11 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 410,839 5.12 7.68 153,600 3,155,244
2015-05-12 2015-05-11 4 INCY INCYTE CORP
Common Stock 		M - Exercise 20,000 410,839 5.12 7.68 153,600 3,155,244
2015-05-12 2015-05-11 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2015-05-12 2015-05-11 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2015-05-12 2015-05-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 26,050,800 0.04 5.11 51,100 133,119,588
2015-05-12 2015-05-11 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 26,050,800 0.04 5.11 51,100 133,119,588
2015-05-07 2015-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,100 26,040,800 0.00 37.07 40,777 965,332,456
2015-05-07 2015-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 46,617 26,039,700 0.18 37.15 1,732,013 967,481,618
2015-05-07 2015-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 8,334 25,993,083 0.03 35.85 298,745 931,761,050
2015-05-07 2015-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 129,118 25,984,749 0.50 36.40 4,700,515 945,969,590
2015-05-07 2015-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 137,800 25,855,631 0.54 36.25 4,995,250 937,266,624
2015-05-07 2015-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 155,731 25,717,831 0.61 36.67 5,710,048 942,972,563
2015-05-07 2015-05-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 23,012 25,562,100 0.09 35.91 826,437 918,019,366
2015-05-07 2015-05-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stoc 		P - Purchase 354,300 25,539,088 1.41 34.76 12,315,078 887,710,606
2015-05-07 2015-05-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 59,973 25,184,788 0.24 34.61 2,075,833 871,716,030
2015-05-07 2015-05-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,330 25,124,815 0.02 33.99 147,177 853,992,462
2015-05-07 2015-05-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 90,397 25,120,485 0.36 34.56 3,123,949 868,116,233
2015-05-07 2015-05-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,952 25,030,088 0.09 34.52 757,888 864,158,782
2015-04-02 2015-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 5,470 59,598 10.11 3.52 19,254 209,785
2015-04-02 2015-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 5,470 59,598 10.11 3.52 19,254 209,785
2015-04-02 2015-04-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 5,470 59,598 10.11 3.52 19,254 209,785
2015-04-02 2015-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 656 306,609 0.21 30.43 19,962 9,330,112
2015-04-02 2015-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 656 1,349,991 0.05 30.43 19,962 41,080,226
2015-04-02 2015-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 656 1,349,991 0.05 30.43 19,962 41,080,226
2015-04-02 2015-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 656 1,349,991 0.05 30.43 19,962 41,080,226
2015-04-02 2015-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 656 1,349,991 0.05 30.43 19,962 41,080,226
2015-04-02 2015-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 656 306,609 0.21 30.43 19,962 9,330,112
2015-03-11 2015-03-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,880 25,008,136 0.01 34.72 99,986 868,217,461
2015-03-11 2015-03-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,439 25,005,256 0.03 34.47 221,935 861,863,660
2015-03-11 2015-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 158,771 24,998,817 0.64 34.69 5,507,401 867,151,464
2015-03-11 2015-03-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 116,946 24,840,046 0.47 34.62 4,049,208 860,076,657
2015-03-05 2015-03-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 19,600 24,723,100 0.08 34.82 682,537 860,939,928
2015-03-05 2015-03-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,021 24,703,500 0.02 34.79 139,882 859,380,417
2015-03-05 2015-03-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 213,820 24,699,479 0.87 34.76 7,432,169 858,529,191
2015-03-05 2015-03-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 211,400 24,485,659 0.87 34.92 7,382,532 855,090,632
2015-02-26 2015-02-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,000 24,274,259 0.00 35.60 35,595 864,042,249
2015-02-26 2015-02-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 62,650 24,273,259 0.26 34.46 2,159,163 836,551,171
2015-02-26 2015-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 163,054 24,210,609 0.68 33.80 5,510,818 818,258,058
2015-02-26 2015-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,995 24,047,555 0.02 33.60 167,830 807,985,824
2015-02-26 2015-02-24 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 49,416 24,042,560 0.21 33.65 1,662,843 809,029,740
2015-02-17 2015-02-13 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 4,898,409 6,323,855 343.64 3.75 18,369,034 23,714,456
2015-02-17 2015-02-13 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		P - Purchase 434,924 625,495 228.22 3.75 1,630,965 2,345,606
2015-02-02 2015-01-29 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 390,935 2,604,832 17.66 20.00 7,818,700 52,096,640
2015-02-02 2015-01-29 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 34,065 159,934 27.06 20.00 681,300 3,198,680
2015-01-09 2015-01-07 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 1,000,000 9,184,771 12.22 94.19 94,190,000 865,113,580
2015-01-06 2015-01-06 4 XOMA XOMA Corp
Common Stock 		S - Sale -21,441 345,074 -5.85 3.86 -82,762 1,331,986
2015-01-06 2015-01-06 4 XOMA XOMA Corp
Common Stock 		S - Sale -859,988 12,589,950 -6.39 3.86 -3,319,554 48,597,207
2015-01-06 2015-01-06 4 XOMA XOMA Corp
Common Stock 		S - Sale -118,571 1,851,789 -6.02 3.86 -457,684 7,147,906
2015-01-06 2015-01-05 4 XOMA XOMA Corp
Common Stock 		S - Sale -21,548 366,515 -5.55 3.81 -82,130 1,396,972
2015-01-06 2015-01-05 4 XOMA XOMA Corp
Common Stock 		S - Sale -863,100 13,449,938 -6.03 3.81 -3,289,706 51,264,439
2015-01-06 2015-01-05 4 XOMA XOMA Corp
Common Stock 		S - Sale -118,652 1,970,360 -5.68 3.81 -452,242 7,510,027
2015-01-06 2015-01-02 4 XOMA XOMA Corp
Common Stock 		S - Sale -4,554 388,063 -1.16 3.55 -16,184 1,379,059
2015-01-06 2015-01-02 4 XOMA XOMA Corp
Common Stock 		S - Sale -182,454 14,313,038 -1.26 3.55 -648,387 50,864,243
2015-01-06 2015-01-02 4 XOMA XOMA Corp
Common Stock 		S - Sale -25,092 2,089,012 -1.19 3.55 -89,169 7,423,722
2015-01-06 2015-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,927 54,128 7.82 4.90 19,242 265,227
2015-01-06 2015-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,927 54,128 7.82 4.90 19,242 265,227
2015-01-06 2015-01-02 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 3,927 1,425,446 0.28 4.90 19,242 6,984,685
2015-01-05 2015-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 624 305,953 0.20 31.97 19,949 9,781,317
2015-01-05 2015-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 624 1,349,335 0.05 31.97 19,949 43,138,240
2015-01-05 2015-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 624 11,420,289 0.01 31.97 19,949 365,106,639
2015-01-05 2015-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 624 1,909,412 0.03 31.97 19,949 61,043,902
2015-01-05 2015-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 624 193,242 0.32 31.97 19,949 6,177,947
2015-01-05 2015-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 624 353,901 0.18 31.97 19,949 11,314,215
2014-12-30 2014-12-30 4 XOMA XOMA Corp
Common Stock 		S - Sale -8,415 392,617 -2.10 3.65 -30,711 1,432,856
2014-12-30 2014-12-30 4 XOMA XOMA Corp
Common Stock 		S - Sale -337,123 14,495,492 -2.27 3.65 -1,230,330 52,901,298
2014-12-30 2014-12-30 4 XOMA XOMA Corp
Common Stock 		S - Sale -46,362 2,114,104 -2.15 3.65 -169,198 7,715,423
2014-12-30 2014-12-29 4 XOMA XOMA Corp
Common Stock 		S - Sale -4,746 401,032 -1.17 3.68 -17,447 1,474,274
2014-12-30 2014-12-29 4 XOMA XOMA Corp
Common Stock 		S - Sale -190,117 14,832,615 -1.27 3.68 -698,908 54,527,659
2014-12-30 2014-12-29 4 XOMA XOMA Corp
Common Stock 		S - Sale -26,137 2,160,466 -1.20 3.68 -96,085 7,942,305
2014-12-30 2014-12-26 4 XOMA XOMA Corp
Common Stock 		S - Sale -2,825 405,778 -0.69 3.71 -10,482 1,505,680
2014-12-30 2014-12-26 4 XOMA XOMA Corp
Common Stock 		S - Sale -112,855 15,022,732 -0.75 3.71 -418,760 55,743,349
2014-12-30 2014-12-26 4 XOMA XOMA Corp
Common Stock 		S - Sale -15,420 2,186,603 -0.70 3.71 -57,217 8,113,609
2014-12-19 2014-12-19 4 XOMA XOMA Corp
Common Stock 		S - Sale -16,182 408,603 -3.81 4.21 -68,102 1,719,606
2014-12-19 2014-12-19 4 XOMA XOMA Corp
Common Stock 		S - Sale -647,781 15,135,587 -4.10 4.21 -2,726,186 63,698,118
2014-12-19 2014-12-19 4 XOMA XOMA Corp
Common Stock 		S - Sale -88,937 2,202,023 -3.88 4.21 -374,291 9,267,214
2014-12-19 2014-12-18 4 XOMA XOMA Corp
Common Stock 		S - Sale -3,558 424,785 -0.83 4.29 -15,260 1,821,903
2014-12-19 2014-12-18 4 XOMA XOMA Corp
Common Stock 		S - Sale -142,543 15,783,368 -0.90 4.29 -611,367 67,694,865
2014-12-19 2014-12-18 4 XOMA XOMA Corp
Common Stock 		S - Sale -19,599 2,290,960 -0.85 4.29 -84,060 9,825,927
2014-12-19 2014-12-17 4 XOMA XOMA Corp
Common Stock 		S - Sale -14,753 428,343 -3.33 4.31 -63,571 1,845,730
2014-12-19 2014-12-17 4 XOMA XOMA Corp
Common Stock 		S - Sale -590,638 15,925,911 -3.58 4.31 -2,545,059 68,624,750
2014-12-19 2014-12-17 4 XOMA XOMA Corp
Common Stock 		S - Sale -81,109 2,310,559 -3.39 4.31 -349,499 9,956,199
2014-12-17 2014-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,900 23,993,144 0.02 31.97 124,679 767,036,821
2014-12-17 2014-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 500 23,989,244 0.00 30.80 15,400 738,868,715
2014-12-17 2014-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 49,685 23,988,744 0.21 31.82 1,581,096 763,379,407
2014-12-17 2014-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,855,894 23,939,059 8.40 31.94 59,276,698 764,606,363
2014-12-17 2014-12-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 597,000 22,083,165 2.78 31.75 18,954,631 701,136,072
2014-12-17 2014-12-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 305,532 21,486,165 1.44 31.68 9,680,415 680,763,355
2014-12-17 2014-12-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 70,867 21,180,633 0.34 31.41 2,226,244 665,376,877
2014-12-16 2014-12-16 4 XOMA XOMA Corp
Common Stock 		S - Sale -6,874 443,096 -1.53 4.27 -29,358 1,892,419
2014-12-16 2014-12-16 4 XOMA XOMA Corp
Common Stock 		S - Sale -274,734 16,516,549 -1.64 4.27 -1,173,361 70,540,529
2014-12-16 2014-12-16 4 XOMA XOMA Corp
Common Stock 		S - Sale -37,592 2,391,668 -1.55 4.27 -160,552 10,214,575
2014-12-16 2014-12-15 4 XOMA XOMA Corp
Common Stock 		S - Sale -9,908 449,970 -2.15 4.45 -44,093 2,002,456
2014-12-16 2014-12-15 4 XOMA XOMA Corp
Common Stock 		S - Sale -396,496 16,791,283 -2.31 4.45 -1,764,486 74,724,568
2014-12-16 2014-12-15 4 XOMA XOMA Corp
Common Stock 		S - Sale -54,396 2,429,260 -2.19 4.45 -242,073 10,810,693
2014-12-16 2014-12-12 4 XOMA XOMA Corp
Common Stock 		S - Sale -5,457 459,878 -1.17 4.71 -25,724 2,167,865
2014-12-16 2014-12-12 4 XOMA XOMA Corp
Common Stock 		S - Sale -218,383 17,187,779 -1.25 4.71 -1,029,457 81,023,190
2014-12-16 2014-12-12 4 XOMA XOMA Corp
Common Stock 		S - Sale -29,960 2,483,656 -1.19 4.71 -141,231 11,707,954
2014-12-10 2014-12-09 4 XOMA XOMA Corp
Common Stock 		S - Sale -8,429 465,335 -1.78 4.62 -38,907 2,147,940
2014-12-10 2014-12-09 4 XOMA XOMA Corp
Common Stock 		S - Sale -337,541 17,406,162 -1.90 4.62 -1,558,056 80,345,103
2014-12-10 2014-12-09 4 XOMA XOMA Corp
Common Stock 		S - Sale -46,383 2,513,616 -1.81 4.62 -214,099 11,602,600
2014-12-10 2014-12-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 100,000 21,109,766 0.48 34.95 3,495,000 737,786,322
2014-12-10 2014-12-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 354,000 21,009,766 1.71 34.27 12,131,651 720,008,883
2014-12-10 2014-12-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 14,772 20,655,766 0.07 34.53 510,114 713,295,239
2014-12-10 2014-12-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 185,378 20,640,994 0.91 34.33 6,364,935 708,706,465
2014-12-10 2014-12-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other 30,507 107,504 39.62
2014-12-10 2014-12-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other 30,507 3,993,087 0.77
2014-12-10 2014-12-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other -399,208 0 -100.00
2014-12-10 2014-12-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,500 20,455,616 0.03 33.90 186,438 693,400,380
2014-12-10 2014-12-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 80,430 20,450,116 0.39 34.64 2,786,393 708,467,684
2014-12-10 2014-12-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 42,500 20,369,686 0.21 33.28 1,414,515 677,958,148
2014-12-10 2014-12-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 185,528 20,327,186 0.92 33.31 6,180,420 677,151,416
2014-12-10 2014-12-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 216,284 20,141,658 1.09 32.56 7,043,267 655,911,079
2014-12-10 2014-12-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 38,614 19,925,374 0.19 33.00 1,274,254 657,533,357
2014-12-10 2014-12-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 24,890 19,886,760 0.13 33.06 822,744 657,360,829
2014-12-04 2014-12-04 4 XOMA XOMA Corp
Common Stock 		S - Sale -28,086 473,764 -5.60 4.55 -127,671 2,153,589
2014-12-04 2014-12-04 4 XOMA XOMA Corp
Common Stock 		S - Sale -1,122,584 17,743,703 -5.95 4.55 -5,102,930 80,657,551
2014-12-04 2014-12-04 4 XOMA XOMA Corp
Common Stock 		S - Sale -153,618 2,559,999 -5.66 4.55 -698,301 11,636,987
2014-12-04 2014-12-03 4 XOMA XOMA Corp
Common Stock 		S - Sale -11,965 501,850 -2.33 4.84 -57,913 2,429,054
2014-12-04 2014-12-03 4 XOMA XOMA Corp
Common Stock 		S - Sale -486,800 18,866,287 -2.52 4.84 -2,356,209 91,316,602
2014-12-04 2014-12-03 4 XOMA XOMA Corp
Common Stock 		S - Sale -69,153 2,713,617 -2.49 4.84 -334,714 13,134,449
2014-12-04 2014-12-02 4 XOMA XOMA Corp
Common Stock 		S - Sale -10,534 513,815 -2.01 5.36 -56,453 2,753,586
2014-12-04 2014-12-02 4 XOMA XOMA Corp
Common Stock 		S - Sale -428,583 19,353,087 -2.17 5.36 -2,296,819 103,715,129
2014-12-04 2014-12-02 4 XOMA XOMA Corp
Common Stock 		S - Sale -60,883 2,782,770 -2.14 5.36 -326,278 14,913,143
2014-11-10 2014-11-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 98,076 19,861,870 0.50 36.57 3,586,737 726,368,448
2014-11-10 2014-11-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,639 19,763,794 0.05 36.75 390,999 726,349,075
2014-11-10 2014-11-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 69,397 19,753,155 0.35 35.88 2,490,291 708,836,041
2014-11-10 2014-11-10 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 63,137 19,683,758 0.32 36.74 2,319,502 723,134,028
2014-11-10 2014-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 25,505 19,620,621 0.13 35.91 915,851 704,550,993
2014-11-10 2014-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 22,839 19,595,116 0.12 35.55 811,963 696,637,726
2014-11-10 2014-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,116 19,572,277 0.07 35.56 466,413 696,001,913
2014-11-10 2014-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 17,098 19,559,161 0.09 34.91 596,816 682,724,250
2014-11-10 2014-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 104,140 19,542,063 0.54 35.98 3,746,947 703,121,473
2014-11-10 2014-11-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 29,006 19,437,923 0.15 35.28 1,023,471 685,863,225
2014-11-10 2014-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,500 19,408,917 0.07 34.26 462,530 664,978,610
2014-11-10 2014-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 25,769 19,395,417 0.13 34.58 890,989 670,615,938
2014-11-10 2014-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 866,669 19,369,648 4.68 33.79 29,287,172 654,554,641
2014-11-10 2014-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 4,394 18,502,979 0.02 33.71 148,139 623,807,584
2014-11-10 2014-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 38,166 18,498,585 0.21 34.83 1,329,390 644,339,013
2014-11-10 2014-11-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 252,474 18,460,419 1.39 34.41 8,686,949 635,173,175
2014-10-03 2014-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,914 50,201 21.59 2.16 19,254 108,434
2014-10-03 2014-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,914 50,201 21.59 2.16 19,254 108,434
2014-10-03 2014-10-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 8,914 1,421,519 0.63 2.16 19,254 3,070,481
2014-10-03 2014-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 700 305,329 0.23 28.54 19,978 8,714,090
2014-10-03 2014-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 700 305,329 0.23 28.54 19,978 8,714,090
2014-10-03 2014-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 700 1,348,711 0.05 28.54 19,978 38,492,212
2014-10-03 2014-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 700 11,419,665 0.01 28.54 19,978 325,917,239
2014-10-03 2014-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 700 192,618 0.36 28.54 19,978 5,497,318
2014-10-03 2014-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 700 353,277 0.20 28.54 19,978 10,082,526
2014-09-16 2014-09-12 4 XOMA XOMA Corp
Non-Qualified Stock Option (right to buy) 		A - Award 7,000 7,000
2014-09-16 2014-09-12 4 XOMA XOMA Corp
Common Shares 		A - Award 5,500 524,349 1.06
2014-09-16 2014-09-12 4 XOMA XOMA Corp
Common Shares 		A - Award 5,500 524,349 1.06
2014-09-16 2014-09-12 4 XOMA XOMA Corp
Common Shares 		A - Award 5,500 524,349 1.06
2014-07-03 2014-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 6,182 41,287 17.61 2.83 17,495 116,842
2014-07-03 2014-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 6,182 41,287 17.61 2.83 17,495 116,842
2014-07-03 2014-07-01 4 IDRA IDERA PHARMACEUTICALS, INC.
Common Stock 		A - Award 6,182 1,412,605 0.44 2.83 17,495 3,997,672
2014-07-03 2014-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 716 304,629 0.24 27.86 19,948 8,486,964
2014-07-03 2014-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 716 1,348,011 0.05 27.86 19,948 37,555,586
2014-07-03 2014-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 716 11,418,965 0.01 27.86 19,948 318,132,365
2014-07-03 2014-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 716 1,908,088 0.04 27.86 19,948 53,159,332
2014-07-03 2014-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 716 191,918 0.37 27.86 19,948 5,346,835
2014-07-03 2014-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 716 352,577 0.20 27.86 19,948 9,822,795
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -4,250 0 -100.00
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 223,864 1.94 60.45 256,912 13,532,579
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 223,864 1.94 60.45 256,912 13,532,579
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 223,864 1.94 60.45 256,912 13,532,579
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 257,722 1.68 60.45 256,912 15,579,295
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 1,893,297 0.22 60.45 256,912 114,449,804
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 212,711 2.04 60.45 256,912 12,858,380
2014-06-24 2014-06-20 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 4,250 322,445 1.34 60.45 256,912 19,491,800
2014-06-16 2014-06-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 670 416,208 0.16 39.80 26,668 16,566,494
2014-06-16 2014-06-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 27,046 18,207,945 0.15 39.80 1,076,523 724,738,118
2014-06-16 2014-06-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,471 415,538 0.36 39.93 58,731 16,590,770
2014-06-16 2014-06-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 59,400 18,180,899 0.33 39.93 2,371,604 725,890,573
2014-06-16 2014-06-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,938 414,067 0.47 39.99 77,503 16,559,036
2014-06-16 2014-06-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 78,262 18,121,499 0.43 39.99 3,129,791 724,700,491
2014-06-16 2014-06-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,155 412,129 0.28 39.84 46,021 16,421,239
2014-06-16 2014-06-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 46,653 18,043,237 0.26 39.84 1,858,884 718,930,974
2014-06-11 2014-06-09 4 IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 70,000 70,000
2014-06-10 2014-06-06 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 12,500 12,500
2014-06-10 2014-06-06 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Options (right to buy) 		A - Award 20,000 20,000
2014-06-09 2014-06-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,534 410,974 1.36 38.96 215,578 16,009,574
2014-06-09 2014-06-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 223,466 17,996,584 1.26 38.96 8,705,163 701,060,529
2014-06-09 2014-06-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 534 405,440 0.13 38.56 20,591 15,633,847
2014-06-09 2014-06-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 21,559 17,773,118 0.12 38.56 831,319 685,334,985
2014-06-09 2014-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 477 404,906 0.12 37.52 17,895 15,190,413
2014-06-09 2014-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 19,223 17,751,559 0.11 37.52 721,168 665,965,712
2014-06-09 2014-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,757 404,429 0.94 37.40 140,504 15,124,795
2014-06-09 2014-06-06 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 151,530 17,732,336 0.86 37.40 5,666,904 663,152,128
2014-06-09 2014-06-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,411 400,672 0.61 37.67 90,826 15,093,995
2014-06-09 2014-06-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 97,254 17,580,806 0.56 37.67 3,663,724 662,298,849
2014-06-09 2014-06-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 496 398,261 0.12 37.63 18,667 14,988,274
2014-06-09 2014-06-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 20,011 17,483,552 0.11 37.63 753,100 657,981,241
2014-06-06 2014-06-04 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		A - Award 15,000 15,000
2014-06-04 2014-06-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,534 397,765 0.39 36.04 55,281 14,334,377
2014-06-04 2014-06-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 61,878 17,463,541 0.36 36.04 2,229,916 629,338,866
2014-06-04 2014-06-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 572 396,231 0.14 36.39 20,817 14,419,995
2014-06-04 2014-06-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 23,058 17,401,663 0.13 36.39 839,147 633,296,981
2014-06-04 2014-06-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 19 395,659 0.00 35.27 670 13,956,001
2014-06-04 2014-06-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 781 17,378,605 0.00 35.27 27,548 612,992,058
2014-06-04 2014-06-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,137 395,640 0.54 34.38 73,479 13,603,725
2014-06-04 2014-06-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 86,201 17,377,824 0.50 34.38 2,963,944 597,520,838
2014-06-04 2014-06-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 270 393,503 0.07 35.11 9,481 13,817,386
2014-06-04 2014-06-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 10,896 17,291,623 0.06 35.11 382,600 607,174,592
2014-06-04 2014-06-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,809 393,233 0.46 34.05 61,604 13,391,196
2014-06-04 2014-06-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 72,980 17,280,727 0.42 34.05 2,485,268 588,479,605
2014-06-04 2014-06-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 480 391,424 0.12 34.21 16,421 13,391,046
2014-06-04 2014-06-02 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 19,348 17,207,747 0.11 34.21 661,916 588,695,953
2014-05-29 2014-05-28 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		A - Award 15,000 15,000
2014-05-27 2014-05-22 4 XOMA XOMA Corp
Non-Qualified Stock Option (right to buy) 		A - Award 11,600 11,600
2014-05-27 2014-05-22 4 XOMA XOMA Corp
Common Shares 		A - Award 8,400 518,849 1.65
2014-05-27 2014-05-22 4 XOMA XOMA Corp
Common Shares 		A - Award 8,400 518,849 1.65
2014-05-27 2014-05-22 4 XOMA XOMA Corp
Common Shares 		A - Award 8,400 518,849 1.65
2014-05-23 2014-05-21 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2014-05-23 2014-05-21 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2014-05-23 2014-05-21 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2014-05-23 2014-05-21 4 INCY INCYTE CORP
Common Stock 		M - Exercise 10,000 390,839 2.63 7.02 70,200 2,743,690
2014-05-23 2014-05-21 4 INCY INCYTE CORP
Common Stock 		M - Exercise 10,000 390,839 2.63 7.02 70,200 2,743,690
2014-05-23 2014-05-21 4 INCY INCYTE CORP
Common Stock 		M - Exercise 10,000 390,839 2.63 7.02 70,200 2,743,690
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 8,750 8,750
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 8,750 8,750
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		A - Award 8,750 8,750
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,151 390,944 0.30 34.08 39,232 13,325,287
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 46,460 17,188,399 0.27 34.08 1,583,584 585,864,861
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,921 389,793 0.76 34.03 99,415 13,266,449
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 117,879 17,141,939 0.69 34.03 4,011,965 583,419,037
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,500 386,872 0.91
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,500 386,872 0.91
2014-05-16 2014-05-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,500 17,178,061 0.02
2014-05-16 2014-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 505 383,372 0.13 34.26 17,304 13,136,012
2014-05-16 2014-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 20,395 17,020,560 0.12 34.26 698,822 583,199,276
2014-05-16 2014-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 7 382,867 0.00 34.10 239 13,055,765
2014-05-16 2014-05-15 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 293 17,000,165 0.00 34.10 9,991 579,705,626
2014-05-16 2014-05-14 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2014-05-16 2014-05-14 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2014-05-16 2014-05-14 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 0 -100.00
2014-05-16 2014-05-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 382,860 2.68 7.26 72,600 2,779,564
2014-05-16 2014-05-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 382,860 2.68 7.26 72,600 2,779,564
2014-05-16 2014-05-14 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		M - Exercise 10,000 382,860 2.68 7.26 72,600 2,779,564
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 746 372,860 0.20 34.60 25,815 12,902,522
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 30,122 16,989,872 0.18 34.60 1,042,348 587,920,929
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 740 372,114 0.20 33.73 24,964 12,553,191
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 29,865 16,959,750 0.18 33.73 1,007,490 572,133,774
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,069 371,374 0.29 34.31 36,673 12,740,319
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 43,131 16,929,885 0.26 34.31 1,479,648 580,794,942
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 783 370,305 0.21 33.92 26,559 12,560,486
2014-05-16 2014-05-09 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 31,617 16,886,754 0.19 33.92 1,072,427 572,786,875
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 329 369,522 0.09 34.74 11,430 12,837,564
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,271 16,855,137 0.08 34.74 461,048 585,564,315
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,933 369,193 0.80 33.77 99,060 12,469,235
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 118,389 16,841,866 0.71 33.77 3,998,506 568,822,235
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 839 366,260 0.23 33.72 28,295 12,352,009
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 33,868 16,723,477 0.20 34.72 1,176,056 580,717,722
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,534 365,421 0.42 33.98 52,118 12,415,252
2014-05-16 2014-05-08 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 61,892 16,689,609 0.37 33.98 2,102,793 567,032,804
2014-05-16 2014-05-07 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 623 363,887 0.17 34.01 21,190 12,376,779
2014-05-16 2014-05-07 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 25,156 16,627,717 0.15 34.01 855,623 565,553,550
2014-05-16 2014-05-07 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,228 363,264 0.34 33.40 41,020 12,134,580
2014-05-16 2014-05-07 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 49,553 16,602,561 0.30 33.40 1,655,283 554,596,928
2014-05-16 2014-05-07 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 984 362,036 0.27 33.54 33,007 12,143,991
2014-05-16 2014-05-07 4/A SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 39,710 16,553,008 0.24 33.54 1,332,016 555,247,479
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 746 372,860 0.20 34.60 25,815 12,902,522
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 30,122 16,989,872 0.18 34.60 1,042,348 587,920,929
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 740 372,114 0.20 33.73 24,964 12,553,191
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 29,865 16,959,750 0.18 33.73 1,007,490 572,133,774
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,069 371,374 0.29 34.31 36,673 12,740,319
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 43,131 16,929,885 0.26 34.31 1,479,648 580,794,942
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 783 370,305 0.21 33.92 26,559 12,560,486
2014-05-09 2013-05-09 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 31,617 16,886,754 0.19 33.92 1,072,427 572,786,875
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 329 369,522 0.09 34.74 11,430 12,837,564
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,271 16,855,137 0.08 34.74 461,048 585,564,315
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,933 369,193 0.80 33.77 99,060 12,469,235
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 118,389 16,841,866 0.71 33.77 3,998,506 568,822,235
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 839 366,260 0.23 33.72 28,295 12,352,009
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 33,868 16,723,477 0.20 34.72 1,176,056 580,717,722
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,534 365,421 0.42 33.98 52,118 12,415,252
2014-05-09 2013-05-08 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 61,892 16,689,609 0.37 33.98 2,102,793 567,032,804
2014-05-09 2013-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 623 363,887 0.17 34.01 21,190 12,376,779
2014-05-09 2013-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 25,156 16,627,717 0.15 34.01 855,623 565,553,550
2014-05-09 2013-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,228 363,264 0.34 33.40 41,020 12,134,580
2014-05-09 2013-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 49,553 16,602,561 0.30 33.40 1,655,283 554,596,928
2014-05-09 2013-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 984 362,036 0.27 33.54 33,007 12,143,991
2014-05-09 2013-05-07 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 39,710 16,553,008 0.24 33.54 1,332,016 555,247,479
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise 8,000 0 -100.00 65.10 520,800
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 219,614 3.78 65.10 520,800 14,296,871
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 219,614 3.78 65.10 520,800 14,296,871
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 219,614 3.78 65.10 520,800 14,296,871
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 253,472 3.26 65.10 520,800 16,501,027
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 1,889,047 0.43 65.10 520,800 122,976,960
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 208,461 3.99 65.10 520,800 13,570,811
2014-04-25 2014-04-23 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		M - Exercise 8,000 318,195 2.58 65.10 520,800 20,714,494
2014-04-03 2014-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 752 303,913 0.25 26.57 19,981 8,074,968
2014-04-03 2014-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 752 303,913 0.25 26.57 19,981 8,074,968
2014-04-03 2014-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 752 1,347,295 0.06 26.57 19,981 35,797,628
2014-04-03 2014-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 752 11,418,249 0.01 26.57 19,981 303,382,876
2014-04-03 2014-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 752 1,907,372 0.04 26.57 19,981 50,678,874
2014-04-03 2014-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 752 191,202 0.39 26.57 19,981 5,080,237
2014-03-19 2014-03-17 4 IDRA IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 80,000 80,000
2014-03-12 2014-03-10 4 IDP IDERA PHARMACEUTICALS, INC.
Non-Qualified Stock Option (right to buy) 		A - Award 60,000 60,000
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,784,624
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		3,019,499
2014-03-12 3 IDP IDERA PHARMACEUTICALS, INC.
Common Stock 		1,648,181
2014-03-07 2014-03-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 9,031 211,614 4.46 105.75 955,028 22,378,180
2014-03-07 2014-03-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 365,969 8,172,521 4.69 105.75 38,701,222 864,244,096
2014-03-07 2014-03-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 11,738 452,540 2.66 28.50 334,533 12,897,390
2014-03-07 2014-03-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 475,644 18,476,847 2.64 28.50 13,555,854 526,590,140
2014-03-07 2014-03-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 38,934 1,552,055 2.57 28.50 1,109,619 44,233,568
2014-01-03 2014-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 682 303,161 0.23 29.27 19,962 8,873,522
2014-01-03 2014-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 682 303,161 0.23 29.27 19,962 8,873,522
2014-01-03 2014-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 682 11,243,600 0.01 29.27 19,962 329,100,172
2014-01-03 2014-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 682 1,732,723 0.04 29.27 19,962 50,716,802
2014-01-03 2014-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 682 16,553 4.30 29.27 19,962 484,506
2014-01-03 2014-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 682 177,212 0.39 29.27 19,962 5,186,995
2013-12-16 2013-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 639 361,052 0.18 39.91 25,504 14,410,344
2013-12-16 2013-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 25,596 16,513,298 0.16 39.91 1,021,590 659,080,401
2013-12-16 2013-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,280 360,413 0.36 39.92 51,100 14,388,372
2013-12-16 2013-12-16 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 51,244 16,487,702 0.31 39.92 2,045,758 658,220,390
2013-12-16 2013-12-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,063 359,133 0.30 39.65 42,153 14,241,383
2013-12-16 2013-12-13 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 42,646 16,436,458 0.26 39.65 1,691,123 651,786,098
2013-12-16 2013-12-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,486 358,070 0.70 39.70 98,694 14,215,379
2013-12-16 2013-12-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 99,775 16,393,812 0.61 39.70 3,961,068 650,834,336
2013-12-16 2013-12-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,377 355,584 0.39 39.54 54,442 14,058,725
2013-12-16 2013-12-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 55,256 16,294,037 0.34 39.54 2,184,656 644,217,341
2013-12-16 2013-12-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,056 354,207 0.87 39.53 120,798 14,001,201
2013-12-16 2013-12-12 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 122,660 16,238,781 0.76 39.53 4,848,541 641,891,407
2013-12-05 2013-12-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 5,492 351,151 1.59 43.98 241,512 15,441,935
2013-12-05 2013-12-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 219,958 16,116,121 1.38 43.98 9,672,697 708,709,644
2013-12-05 2013-12-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 553 345,659 0.16 44.00 24,332 15,208,823
2013-12-05 2013-12-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 22,147 15,896,163 0.14 44.00 974,457 699,423,224
2013-12-05 2013-12-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,863 345,106 0.84 44.05 126,102 15,200,366
2013-12-05 2013-12-05 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 114,663 15,874,016 0.73 44.05 5,050,389 699,178,972
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 170 342,243 0.05 43.42 7,382 14,861,800
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 6,814 15,759,353 0.04 43.42 295,896 684,345,176
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,512 342,073 0.74 42.95 107,883 14,691,043
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 100,626 15,752,539 0.64 42.95 4,321,595 676,525,868
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 340 339,561 0.10 43.72 14,864 14,845,233
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 13,632 15,651,913 0.09 43.72 595,976 684,284,419
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,011 339,221 0.30 43.01 43,479 14,588,403
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 40,471 15,638,281 0.26 43.01 1,740,480 672,533,657
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 1,818 338,210 0.54 43.20 78,547 14,612,329
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 72,807 15,597,810 0.47 43.20 3,145,619 673,901,821
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 455 336,392 0.14 43.64 19,858 14,681,829
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 18,232 15,525,003 0.12 43.64 795,736 677,588,756
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 290 335,937 0.09 42.65 12,369 14,328,721
2013-12-05 2013-12-04 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 11,617 15,506,771 0.07 42.65 495,500 661,410,303
2013-12-05 2013-12-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 3,551 335,647 1.07 42.56 151,129 14,284,968
2013-12-05 2013-12-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 142,220 15,495,154 0.93 42.56 6,052,812 659,466,007
2013-12-05 2013-12-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,632 332,096 0.80 42.41 111,631 14,085,188
2013-12-05 2013-12-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 105,414 15,352,934 0.69 42.41 4,470,924 651,163,990
2013-12-05 2013-12-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 2,816 329,464 0.86 42.31 119,144 13,939,556
2013-12-05 2013-12-03 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		P - Purchase 112,797 15,247,520 0.75 42.31 4,772,419 645,119,522
2013-11-13 2013-11-08 4 INCY INCYTE CORP
4.75% Convertible Senior Note due 2015 		D - Sale to Issuer -127,000 892,000 -12.46 432.60 -54,940,390 385,880,538
2013-11-13 2013-11-08 4 INCY INCYTE CORP
4.75% Convertible Senior Note due 2015 		D - Sale to Issuer -4,567,000 31,967,000 -12.50 432.60 -1,975,691,050 13,828,972,150
2013-11-13 2013-11-08 4 INCY INCYTE CORP
4.75% Convertible Senior Note due 2015 		D - Sale to Issuer -1,084,000 7,587,000 -12.50 432.60 -468,940,026 3,282,147,580
2013-11-13 2013-11-08 4 INCY INCYTE CORP
4.75% Convertible Senior Note due 2015 		D - Sale to Issuer -2,459,000 1,019,000 -70.70 425.88 -1,047,233,756 433,969,580
2013-11-13 2013-11-08 4 INCY INCYTE CORP
4.75% Convertible Senior Note due 2015 		D - Sale to Issuer -88,153,000 36,534,000 -70.70 425.88 -37,542,414,519 15,559,023,199
2013-11-13 2013-11-08 4 INCY INCYTE CORP
4.75% Convertible Senior Note due 2015 		D - Sale to Issuer -20,922,000 8,671,000 -70.70 425.88 -8,910,217,424 3,692,787,271
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 170,000 6,050,000 2.89 104.52 17,768,043 632,333,295
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 6,830,000 243,450,000 2.89 104.52 713,857,257 25,444,882,755
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 242,000 5,880,000 4.29 104.25 25,228,500 612,990,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 9,758,000 236,620,000 4.30 104.25 1,017,271,500 24,667,635,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 61,000 5,638,000 1.09 103.75 6,328,750 584,942,500
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 2,439,000 226,862,000 1.09 103.75 253,046,250 23,536,932,500
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 121,000 5,577,000 2.22 104.75 12,674,750 584,190,750
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 4,879,000 224,423,000 2.22 104.75 511,075,250 23,508,309,250
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 5,456,000 5,456,000 100.00 545,600,000 545,600,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 5,456,000 5,456,000 100.00 545,600,000 545,600,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 219,544,000 219,544,000 100.00 21,954,400,000 21,954,400,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 219,544,000 219,544,000 100.00 21,954,400,000 21,954,400,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 25,000,000 25,000,000 100.00 2,500,000,000 2,500,000,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
1.25% Convertible Senior Note due 2020 		P - Purchase 25,000,000 25,000,000 100.00 2,500,000,000 2,500,000,000
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 133,000 5,674,000 2.40 104.09 13,844,090 590,611,767
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 5,367,000 228,326,000 2.41 104.09 558,655,860 23,766,658,833
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 85,000 5,541,000 1.56 104.12 8,850,625 576,956,625
2013-11-13 2013-11-08 4 INCY INCYTE CORP
0.375% Convertible Senior Note due 2018 		P - Purchase 3,415,000 222,959,000 1.56 104.12 355,586,875 23,215,605,875
2013-10-28 2013-10-24 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 8,721 40,308 27.61 17.50 152,618 705,390
2013-10-28 2013-10-24 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 346,965 2,213,897 18.58 17.50 6,071,888 38,743,198
2013-10-28 2013-10-24 4 MRTX Mirati Therapeutics, Inc.
Common Stock 		P - Purchase 44,314 125,869 54.34 17.50 775,495 2,202,708
2013-10-02 2013-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 658 302,479 0.22 30.33 19,957 9,174,188
2013-10-02 2013-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 658 11,242,918 0.01 30.33 19,957 340,997,703
2013-10-02 2013-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 658 1,732,041 0.04 30.33 19,957 52,532,804
2013-10-02 2013-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 658 15,871 4.33 30.33 19,957 481,367
2013-10-02 2013-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 658 176,530 0.37 30.33 19,957 5,354,155
2013-10-02 2013-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 658 196,794 0.34 30.33 19,957 5,968,762
2013-09-27 2013-09-25 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 25,663 202,583 14.51 56.63 1,453,296 11,472,275
2013-09-27 2013-09-25 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 1,024,337 7,806,552 15.10 56.63 58,008,204 442,085,040
2013-08-21 2013-08-19 4 XOMA XOMA Corp
Common Stock 		A - Award 21,410 510,449 4.38 3.62 77,504 1,847,825
2013-08-21 2013-08-19 4 XOMA XOMA Corp
Common Stock 		A - Award 1,854,058 19,767,770 10.35 3.62 6,711,690 71,559,327
2013-08-21 2013-08-19 4 XOMA XOMA Corp
Common Stock 		A - Award 882,323 2,829,753 45.31 3.62 3,194,009 10,243,706
2013-08-21 2013-08-19 4/A XOMA XOMA Corp
Common Stock 		P - Purchase 21,410 510,449 4.38 3.62 77,504 1,847,825
2013-08-21 2013-08-19 4/A XOMA XOMA Corp
Common Stock 		P - Purchase 1,854,058 19,767,770 10.35 3.62 6,711,690 71,559,327
2013-08-21 2013-08-19 4/A XOMA XOMA Corp
Common Stock 		P - Purchase 882,323 2,829,753 45.31 3.62 3,194,009 10,243,706
2013-08-02 2013-08-01 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 24,705 145,533 20.45 4.40 108,702 640,345
2013-08-02 2013-08-01 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 991,161 4,832,285 25.80 4.40 4,361,108 21,262,054
2013-08-02 2013-08-01 4 BCRX BIOCRYST PHARMACEUTICALS INC
Common Stock 		P - Purchase 120,498 1,642,513 7.92 4.40 530,191 7,227,057
2013-07-29 2013-07-25 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 3,030 3,030
2013-07-29 2013-07-25 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 3,030 3,030
2013-07-29 2013-07-25 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 3,030 3,030
2013-07-29 2013-07-25 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 3,030 3,030
2013-07-29 2013-07-25 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 3,030 3,030
2013-07-29 2013-07-25 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 3,030 3,030
2013-07-11 3 MYG Mirati Therapeutics, Inc.
Common Stock 		81,555
2013-07-11 3 MYG Mirati Therapeutics, Inc.
Common Stock 		1,866,932
2013-07-11 3 MYG Mirati Therapeutics, Inc.
Common Stock 		31,587
2013-07-03 2013-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 606 301,821 0.20 32.85 19,907 9,914,820
2013-07-03 2013-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 606 301,821 0.20 32.85 19,907 9,914,820
2013-07-03 2013-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 606 301,821 0.20 32.85 19,907 9,914,820
2013-07-03 2013-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 606 1,731,383 0.04 32.85 19,907 56,875,932
2013-07-03 2013-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 606 15,213 4.15 32.85 19,907 499,747
2013-07-03 2013-07-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 606 175,872 0.35 32.85 19,907 5,777,395
2013-06-13 2013-06-11 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 10,000 -50.00 4.44 -44,400 44,400
2013-06-13 2013-06-11 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 10,000 -50.00 4.44 -44,400 44,400
2013-06-13 2013-06-11 4 INCY INCYTE CORP
Non-Qualified Stock Options (right to buy) 		M - Exercise -10,000 10,000 -50.00 4.44 -44,400 44,400
2013-06-13 2013-06-11 4 INCY INCYTE CORP
Common Stock 		M - Exercise 10,000 380,839 2.70 4.44 44,400 1,690,925
2013-06-13 2013-06-11 4 INCY INCYTE CORP
Common Stock 		M - Exercise 10,000 380,839 2.70 4.44 44,400 1,690,925
2013-06-13 2013-06-11 4 INCY INCYTE CORP
Common Stock 		M - Exercise 10,000 12,455,783 0.08 4.44 44,400 55,303,677
2013-06-11 2013-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 16,500 16,500
2013-06-11 2013-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 16,500 16,500
2013-06-11 2013-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 16,500 16,500
2013-06-11 2013-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 16,500 16,500
2013-06-11 2013-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 16,500 16,500
2013-06-11 2013-06-07 4 GHDX GENOMIC HEALTH INC
Non-Qualified Stock Option (right to buy) 		A - Award 16,500 16,500
2013-06-11 2013-06-07 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 12,500 12,500
2013-06-11 2013-06-07 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 12,500 12,500
2013-06-11 2013-06-07 4 ACAD ACADIA PHARMACEUTICALS INC
Non-Qualified Stock Option (right to buy) 		A - Award 12,500 12,500
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-10 2013-06-06 4 GEVA SYNAGEVA BIOPHARMA CORP
Non-Qualified Stock Option (right to buy) 		A - Award 15,000 15,000
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 5,437 440,802 1.25 14.46 78,641 6,375,804
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 217,986 18,001,203 1.23 14.46 3,152,971 260,371,200
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 26,577 1,513,121 1.79 14.46 384,412 21,885,933
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 3,790 435,365 0.88 14.55 55,145 6,334,648
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 151,980 17,783,217 0.86 14.55 2,211,339 258,749,364
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 18,530 1,486,544 1.26 14.55 269,615 21,629,513
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 4,312 431,575 1.01 14.58 62,885 6,294,003
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 172,893 17,631,237 0.99 14.58 2,521,437 257,130,434
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 21,080 1,468,014 1.46 14.58 307,427 21,409,223
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 5,437 427,263 1.29 14.46 78,600 6,176,728
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 217,986 17,458,344 1.26 14.46 3,151,315 252,386,550
2013-06-05 2013-06-05 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stoc 		P - Purchase 26,577 1,446,934 1.87 14.46 384,210 20,917,601
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 2,775 421,826 0.66 14.42 40,004 6,081,001
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 111,266 17,240,358 0.65 14.42 1,604,000 248,535,277
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 13,566 1,420,357 0.96 14.42 195,566 20,475,724
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 11,552 419,051 2.83 14.45 166,955 6,056,335
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 463,197 17,129,092 2.78 14.45 6,694,355 247,558,202
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 56,475 1,406,791 4.18 14.45 816,205 20,331,647
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 890 407,499 0.22 14.50 12,903 5,907,798
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 35,702 16,665,895 0.21 14.50 517,597 241,617,146
2013-06-05 2013-06-04 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 4,353 1,350,316 0.32 14.50 63,108 19,576,476
2013-06-05 2013-06-03 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 5,189 406,609 1.29 14.00 72,641 5,692,119
2013-06-05 2013-06-03 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 208,063 16,630,193 1.27 14.00 2,912,674 232,806,072
2013-06-05 2013-06-03 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 25,368 1,345,963 1.92 14.00 355,127 18,842,136
2013-06-05 2013-06-03 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 11,511 401,420 2.95 14.08 162,100 5,652,877
2013-06-05 2013-06-03 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 461,548 16,422,130 2.89 14.08 6,499,611 231,259,719
2013-06-05 2013-06-03 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 56,274 1,320,595 4.45 14.08 792,462 18,596,883
2013-06-05 2013-06-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,735 301,215 1.60 35.82 169,584 10,788,015
2013-06-05 2013-06-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 189,886 11,241,654 1.72 35.82 6,800,767 402,619,838
2013-06-05 2013-06-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 23,152 1,730,777 1.36 35.82 829,189 61,987,778
2013-06-05 2013-06-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,558 296,480 1.21 36.62 130,294 10,857,098
2013-06-05 2013-06-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 142,702 11,051,768 1.31 36.62 5,225,747 404,715,744
2013-06-05 2013-06-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 17,399 1,707,625 1.03 36.62 637,151 62,533,228
2013-06-03 2013-06-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,790 292,922 0.96 36.69 102,356 10,746,400
2013-06-03 2013-06-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 111,907 10,909,066 1.04 36.69 4,105,521 400,219,813
2013-06-03 2013-06-03 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 13,644 1,690,226 0.81 36.69 500,556 62,009,152
2013-06-03 2013-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,114 290,132 0.39 36.75 40,942 10,662,989
2013-06-03 2013-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 44,627 10,797,159 0.42 36.75 1,640,140 396,819,347
2013-06-03 2013-05-31 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,501 1,676,582 0.33 36.75 202,174 61,618,077
2013-05-29 2013-05-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,021 289,018 0.35 36.82 37,595 10,642,105
2013-05-29 2013-05-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 40,933 10,752,532 0.38 36.82 1,507,219 395,925,432
2013-05-29 2013-05-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,046 1,671,081 0.30 36.82 185,802 61,531,876
2013-05-29 2013-05-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,613 287,997 0.56 36.93 59,574 10,636,852
2013-05-29 2013-05-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 64,679 10,711,599 0.61 36.93 2,388,848 395,621,126
2013-05-29 2013-05-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7,974 1,666,035 0.48 36.93 294,511 61,533,170
2013-05-24 2013-05-23 4 XOMA XOMA Corp
Non-Qualified Stock Option (right to buy) 		A - Award 11,600 11,600
2013-05-24 2013-05-23 4 XOMA XOMA Corp
Non-Qualified Stock Option (right to buy) 		A - Award 11,600 11,600
2013-05-24 2013-05-23 4 XOMA XOMA Corp
Non-Qualified Stock Option (right to buy) 		A - Award 11,600 11,600
2013-05-24 2013-05-23 4 XOMA XOMA Corp
Common Shares 		A - Award 8,400 489,039 1.75
2013-05-24 2013-05-23 4 XOMA XOMA Corp
Common Shares 		A - Award 8,400 489,039 1.75
2013-05-24 2013-05-23 4 XOMA XOMA Corp
Common Shares 		A - Award 8,400 1,947,430 0.43
2013-05-24 2013-05-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,358 286,384 0.48 36.93 50,154 10,576,877
2013-05-24 2013-05-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 54,399 10,646,920 0.51 36.93 2,009,091 393,217,373
2013-05-24 2013-05-24 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 6,760 1,658,061 0.41 36.93 249,664 61,236,338
2013-05-24 2013-05-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 332 285,026 0.12 36.99 12,280 10,542,371
2013-05-24 2013-05-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 13,313 10,592,521 0.13 36.99 492,413 391,789,811
2013-05-24 2013-05-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,655 1,651,301 0.10 36.99 61,214 61,077,331
2013-05-24 2013-05-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 35 284,694 0.01 36.18 1,266 10,300,969
2013-05-24 2013-05-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,392 10,579,208 0.01 36.18 50,366 382,783,251
2013-05-24 2013-05-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 173 1,649,646 0.01 36.18 6,260 59,688,481
2013-05-21 2013-05-17 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Option (right to buy) 		A - Award 8,750 8,750
2013-05-21 2013-05-17 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Option (right to buy) 		A - Award 8,750 8,750
2013-05-21 2013-05-17 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Option (right to buy) 		A - Award 8,750 8,750
2013-05-21 2013-05-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,500 326,648 1.08
2013-05-21 2013-05-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,500 326,648 1.08
2013-05-21 2013-05-17 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		A - Award 3,500 326,648 1.08
2013-05-17 2013-05-15 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 43,184 389,909 12.45 12.50 539,800 4,873,862
2013-05-17 2013-05-15 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 1,730,970 15,960,582 12.16 12.50 21,637,125 199,507,275
2013-05-17 2013-05-15 4 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		P - Purchase 218,846 1,264,321 20.93 12.50 2,735,575 15,804,012
2013-05-16 2013-05-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 418 284,659 0.15 36.54 15,273 10,401,212
2013-05-16 2013-05-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 16,768 10,577,816 0.16 36.54 612,689 386,504,934
2013-05-16 2013-05-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,120 1,649,473 0.13 36.54 77,463 60,270,424
2013-05-16 2013-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,129 284,241 0.40 36.41 41,111 10,350,295
2013-05-16 2013-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 45,279 10,561,048 0.43 36.41 1,648,780 384,567,890
2013-05-16 2013-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,725 1,647,353 0.35 36.41 208,469 59,986,383
2013-05-14 2013-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 589 283,112 0.21 35.53 20,928 10,059,507
2013-05-14 2013-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 23,610 10,515,769 0.23 35.53 838,908 373,645,253
2013-05-14 2013-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,985 1,641,628 0.18 35.53 106,063 58,330,162
2013-05-14 2013-05-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,516 282,523 1.26 34.02 119,609 9,610,980
2013-05-14 2013-05-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 140,962 10,492,159 1.36 34.02 4,795,302 356,926,462
2013-05-14 2013-05-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 17,822 1,638,643 1.10 34.02 606,276 55,744,013
2013-05-14 2013-05-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,104 279,007 0.40 34.74 38,358 9,694,098
2013-05-14 2013-05-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 44,244 10,351,197 0.43 34.74 1,537,258 359,652,340
2013-05-14 2013-05-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,594 1,620,821 0.35 34.74 194,364 56,315,426
2013-04-03 2013-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 714 277,903 0.26 27.99 19,985 7,778,505
2013-04-03 2013-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 714 277,903 0.26 27.99 19,985 7,778,505
2013-04-03 2013-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 714 10,306,953 0.01 27.99 19,985 288,491,614
2013-04-03 2013-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 714 1,615,227 0.04 27.99 19,985 45,210,204
2013-04-03 2013-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 714 14,607 5.14 27.99 19,985 408,850
2013-04-03 2013-04-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 714 175,266 0.41 27.99 19,985 4,905,695
2013-02-21 2013-02-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 612 277,189 0.22 27.63 16,912 7,659,813
2013-02-21 2013-02-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 24,508 10,306,239 0.24 27.64 677,325 284,832,497
2013-02-21 2013-02-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,080 1,614,513 0.19 27.64 85,122 44,620,134
2013-02-21 2013-02-20 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 453 276,577 0.16 27.97 12,672 7,736,744
2013-02-21 2013-02-20 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 18,151 10,281,731 0.18 27.97 507,742 287,612,918
2013-02-21 2013-02-20 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,281 1,611,433 0.14 27.97 63,807 45,076,938
2013-02-14 2013-02-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 758 276,124 0.28 28.43 21,551 7,850,509
2013-02-14 2013-02-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 30,102 10,263,580 0.29 28.43 855,833 291,804,869
2013-02-14 2013-02-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,940 1,609,152 0.25 28.43 112,019 45,749,961
2013-02-14 2013-02-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 375 275,366 0.14 28.58 10,718 7,870,098
2013-02-14 2013-02-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 14,878 10,233,478 0.15 28.58 425,221 292,477,918
2013-02-14 2013-02-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,947 1,605,212 0.12 28.58 55,646 45,877,762
2013-02-11 2013-02-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,742 274,991 0.64 28.23 49,180 7,763,463
2013-02-11 2013-02-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 69,187 10,218,600 0.68 28.23 1,953,267 288,488,450
2013-02-11 2013-02-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 9,055 1,603,265 0.57 28.23 255,638 45,262,897
2013-02-11 2013-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 788 273,249 0.29 27.96 22,033 7,640,288
2013-02-11 2013-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 31,584 10,149,413 0.31 27.96 883,117 283,786,722
2013-02-11 2013-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,004 1,594,210 0.25 27.96 111,955 44,575,546
2013-01-23 2013-01-18 4 ACAD ACADIA PHARMACEUTICALS INC
Stock Options (right to buy) 		A - Award 15,000 15,000
2013-01-08 2013-01-04 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 20,099 176,920 12.82 47.53 955,305 8,409,008
2013-01-08 2013-01-04 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 839,621 6,782,215 14.13 47.53 39,907,186 322,358,679
2013-01-03 2013-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 367 272,461 0.13 27.24 9,997 7,421,838
2013-01-03 2013-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 367 272,461 0.13 27.24 9,997 7,421,838
2013-01-03 2013-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 367 10,117,829 0.00 27.24 9,997 275,609,662
2013-01-03 2013-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 367 1,590,206 0.02 27.24 9,997 43,317,211
2013-01-03 2013-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 367 13,893 2.71 27.24 9,997 378,445
2013-01-03 2013-01-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 367 174,552 0.21 27.24 9,997 4,754,796
2012-12-21 3 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		1,045,475
2012-12-21 3 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		14,229,612
2012-12-21 3 ACAD ACADIA PHARMACEUTICALS INC
Common Stock 		346,725
2012-11-23 2012-11-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 6 271,806 0.00 27.54 165 7,485,537
2012-11-23 2012-11-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 268 10,117,174 0.00 27.54 7,381 278,626,972
2012-11-23 2012-11-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 26 1,589,551 0.00 27.54 716 43,776,235
2012-11-23 2012-11-20 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,859 271,800 1.82 26.83 130,352 7,291,551
2012-11-23 2012-11-20 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 202,311 10,116,906 2.04 26.83 5,427,377 271,405,226
2012-11-23 2012-11-20 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 21,830 1,589,525 1.39 26.83 585,631 42,642,028
2012-11-14 2012-11-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,223 266,941 0.84 27.32 60,725 7,291,894
2012-11-14 2012-11-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 92,592 9,914,595 0.94 27.32 2,529,289 270,832,034
2012-11-14 2012-11-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 8,352 1,567,695 0.54 27.32 228,147 42,823,940
2012-11-14 2012-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,231 264,718 0.85 27.99 62,450 7,409,960
2012-11-14 2012-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 92,917 9,822,003 0.96 27.99 2,600,923 274,936,526
2012-11-14 2012-11-13 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 8,691 1,559,343 0.56 27.99 243,278 43,648,973
2012-11-14 2012-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,298 262,487 1.66 27.94 120,075 7,333,204
2012-11-14 2012-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 178,978 9,729,086 1.87 27.94 5,000,180 271,805,367
2012-11-14 2012-11-12 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 16,724 1,550,652 1.09 27.94 467,225 43,321,185
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 143 258,189 0.06 27.86 3,983 7,192,010
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 24 258,046 0.01 26.68 640 6,884,693
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 79 258,022 0.03 27.16 2,146 7,008,187
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 9,905 257,943 3.99 27.84 275,793 7,182,113
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 651 248,038 0.26 26.91 17,516 6,673,735
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 324 247,387 0.13 25.83 8,367 6,388,868
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,972 9,550,108 0.06 27.86 166,354 266,023,988
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 980 9,544,136 0.01 26.68 26,146 254,638,503
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,298 9,543,156 0.03 27.16 89,578 259,203,569
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 412,596 9,539,858 4.52 27.84 11,488,241 265,625,898
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 27,125 9,127,262 0.30 26.91 729,828 245,579,024
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 13,447 9,100,137 0.15 25.83 347,274 235,014,678
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 585 1,533,928 0.04 27.86 16,296 42,728,485
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 96 1,533,343 0.01 26.68 2,561 40,909,745
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 323 1,533,247 0.02 27.16 8,773 41,644,828
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 40,412 1,532,924 2.71 27.84 1,125,224 42,682,429
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,657 1,492,512 0.18 26.91 71,490 40,157,677
2012-11-14 2012-11-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,316 1,489,855 0.09 25.83 33,986 38,476,101
2012-10-31 2012-10-29 4 XOMA XOMA Corp
Common Stock 		P - Purchase 103,608 463,839 28.76 3.00 310,824 1,391,517
2012-10-31 2012-10-29 4 XOMA XOMA Corp
Common Stock 		P - Purchase 4,282,419 17,888,512 31.47 3.00 12,847,257 53,665,536
2012-10-31 2012-10-29 4 XOMA XOMA Corp
Common Stock 		P - Purchase 336,639 1,922,230 21.23 3.00 1,009,917 5,766,690
2012-10-03 2012-10-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		A - Award 288 288 35.89 10,336 10,336
2012-07-30 2012-07-26 4 GHDX GENOMIC HEALTH INC
Stock Options (right to buy) 		A - Award 16,500 16,500
2012-07-13 2012-07-13 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 21,082 156,821 15.53 41.20 868,578 6,461,025
2012-07-13 2012-07-13 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		P - Purchase 864,918 5,942,594 17.03 41.20 35,634,622 244,834,873
2012-06-29 2012-06-27 4 GEVA SYNAGEVA BIOPHARMA CORP
Stock Option (Right to Buy) 		A - Award 7,500 7,500
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Stock Option (Right to Buy) 		D - Sale to Issuer -12,500 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Stock Option (Right to Buy) 		D - Sale to Issuer -12,500 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Stock Option (Right to Buy) 		D - Sale to Issuer -25,000 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Warrants 		D - Sale to Issuer -4,023 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Warrants 		D - Sale to Issuer -147,292 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Warrants 		D - Sale to Issuer -46,195 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Warrants 		D - Sale to Issuer -998 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Warrants 		D - Sale to Issuer -205 0 -100.00
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -116,454 0 -100.00 32.00 -3,726,528
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -4,922,226 0 -100.00 32.00 -157,511,232
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -1,646,964 0 -100.00 32.00 -52,702,848
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -99,636 0 -100.00 32.00 -3,188,352
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -65,882 0 -100.00 32.00 -2,108,224
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -60,827 0 -100.00 32.00 -1,946,464
2012-06-21 2012-06-19 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		D - Sale to Issuer -2,302 0 -100.00 32.00 -73,664
2012-05-23 2012-05-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 380 247,063 0.15 32.94 12,518 8,138,922
2012-05-23 2012-05-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 17,026 9,086,690 0.19 32.94 560,882 299,340,103
2012-05-23 2012-05-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,732 246,683 1.12 32.21 87,992 7,945,166
2012-05-23 2012-05-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 546 243,951 0.22 32.04 17,493 7,815,922
2012-05-23 2012-05-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 122,268 9,069,664 1.37 32.21 3,938,008 292,115,738
2012-05-23 2012-05-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 24,454 8,947,396 0.27 32.04 783,479 286,664,726
2012-05-23 2012-05-18 4 SGEN SEATTLE GENETICS INC /WA
Non-Qualified Stock Option (right to buy) 		A - Award 17,500 17,500
2012-05-16 2012-05-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 517 243,405 0.21 34.46 17,815 8,387,176
2012-05-16 2012-05-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 23,104 8,922,942 0.26 34.46 796,111 307,464,059
2012-05-16 2012-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,972 242,888 0.82 34.25 67,541 8,318,914
2012-05-16 2012-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 540 240,916 0.22 33.11 17,882 7,977,668
2012-05-16 2012-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 555 240,376 0.23 34.47 19,129 8,285,160
2012-05-16 2012-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 88,028 8,899,838 1.00 34.25 3,014,959 304,819,452
2012-05-16 2012-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 24,136 8,811,810 0.27 33.11 799,237 291,793,395
2012-05-16 2012-05-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 24,769 8,787,674 0.28 34.47 853,726 302,889,154
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,212 239,821 1.36 33.92 108,951 8,134,728
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 897 236,609 0.38 33.67 30,198 7,965,513
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 370 235,712 0.16 32.59 12,058 7,681,501
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 175 235,342 0.07 31.53 5,517 7,419,863
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 143,388 8,762,905 1.66 33.92 4,863,721 297,237,738
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 40,073 8,619,517 0.47 33.67 1,349,070 290,178,626
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 16,526 8,579,444 0.19 32.59 538,558 279,591,211
2012-05-16 2012-05-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7,797 8,562,918 0.09 31.53 245,824 269,971,679
2012-05-11 2012-05-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 627 235,167 0.27 30.22 18,946 7,105,877
2012-05-11 2012-05-11 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 26,033 8,555,121 0.31 30.22 786,621 258,504,103
2012-05-11 2012-05-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 214 234,540 0.09 29.98 6,415 7,030,829
2012-05-11 2012-05-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 8,867 8,529,088 0.10 29.98 265,807 255,677,324
2012-05-11 2012-05-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,402 234,326 0.60 29.86 41,861 6,996,599
2012-05-11 2012-05-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 58,198 8,520,221 0.69 29.86 1,737,699 254,400,167
2012-05-11 2012-05-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 460 232,924 0.20 29.90 13,752 6,963,379
2012-05-11 2012-05-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 19,087 8,462,023 0.23 29.90 570,615 252,976,409
2012-05-08 2012-05-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 116 232,464 0.05 28.50 3,306 6,624,620
2012-05-08 2012-05-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,737 232,348 0.75 28.90 50,196 6,714,416
2012-05-08 2012-05-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 172 230,611 0.07 28.41 4,886 6,550,529
2012-05-08 2012-05-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,811 8,442,936 0.06 28.50 137,101 240,601,724
2012-05-08 2012-05-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 72,073 8,438,125 0.86 28.90 2,082,773 243,845,780
2012-05-08 2012-05-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7,124 8,366,052 0.09 28.41 202,358 237,638,544
2012-05-08 2012-05-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 536 230,439 0.23 28.28 15,159 6,517,184
2012-05-08 2012-05-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 754 229,903 0.33 28.25 21,300 6,494,530
2012-05-08 2012-05-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 22,241 8,358,928 0.27 28.28 629,011 236,403,858
2012-05-08 2012-05-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 31,273 8,336,687 0.38 28.25 883,431 235,503,071
2012-05-08 2012-05-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 722 1,488,539 0.05 28.28 20,419 42,098,265
2012-05-08 2012-05-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,014 1,487,817 0.07 28.25 28,644 42,029,342
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5 229,149 0.00 28.00 140 6,416,172
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 369 229,144 0.16 27.99 10,330 6,414,863
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 935 228,775 0.41 28.03 26,208 6,412,540
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 188 8,305,414 0.00 28.00 5,264 232,551,592
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 14,078 8,305,226 0.17 27.99 394,112 232,503,971
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 35,727 8,291,148 0.43 28.03 1,001,424 232,400,049
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7 1,486,803 0.00 28.00 196 41,630,484
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 514 1,486,796 0.03 27.99 14,389 41,622,705
2012-05-08 2012-05-04 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,305 1,486,282 0.09 28.03 36,579 41,660,336
2012-03-14 2012-03-14 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 910 57,704 1.60 3.01 2,735 173,429
2012-03-14 2012-03-14 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 1,482 56,794 2.68 2.99 4,430 169,763
2012-03-14 2012-03-13 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 4,186 55,312 8.19 2.96 12,383 163,618
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 15,076 51,126 41.82 2.55 38,444 130,371
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 8,628 36,050 31.46 2.34 20,186 84,343
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 1,170 27,422 4.46 1.87 2,188 51,279
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 430 26,252 1.67 1.89 811 49,506
2012-03-14 3 TZYM TRANZYME INC
Common Stock 		25,822
2012-03-14 2012-03-14 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 34,544 3,540,015 0.99 3.01 103,822 10,639,515
2012-03-14 2012-03-14 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 56,294 3,505,471 1.63 2.99 168,268 10,478,203
2012-03-14 2012-03-13 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 159,015 3,449,177 4.83 2.96 470,382 10,203,010
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 572,737 3,290,162 21.08 2.55 1,460,479 8,389,913
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 327,769 2,717,425 13.72 2.34 766,848 6,357,688
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 44,467 2,389,656 1.90 1.87 83,153 4,468,657
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 16,326 2,345,189 0.70 1.89 30,788 4,422,557
2012-03-14 3 TZYM TRANZYME INC
Common Stock 		2,328,863
2012-03-14 2012-03-14 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 4,592 232,011 2.02 3.01 13,801 697,309
2012-03-14 2012-03-14 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 7,484 227,419 3.40 2.99 22,370 679,778
2012-03-14 2012-03-13 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 15,599 219,935 7.63 2.96 46,143 650,590
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 56,187 204,336 37.93 2.55 143,277 521,057
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 32,155 148,149 27.72 2.34 75,230 346,609
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 4,363 115,994 3.91 1.87 8,159 216,909
2012-03-14 2012-03-12 4 TZYM TRANZYME INC
Common Stock 		P - Purchase 1,601 111,631 1.46 1.89 3,019 210,514
2012-03-14 3 TZYM TRANZYME INC
Common Stock 		110,030
2012-03-09 2012-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 516 227,840 0.23 30.36 15,668 6,918,088
2012-03-09 2012-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 583 227,324 0.26 29.88 17,420 6,792,259
2012-03-09 2012-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 19,513 8,255,421 0.24 30.36 592,489 250,665,952
2012-03-09 2012-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 22,071 8,235,908 0.27 29.88 659,464 246,082,342
2012-03-09 2012-03-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,162 1,484,977 0.15 30.36 65,647 45,089,545
2012-03-09 2012-03-07 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,346 1,482,815 0.16 29.88 70,097 44,305,326
2012-03-08 3 XOMA XOMA Corp
Common Stock 		360,231
2012-03-08 3 XOMA XOMA Corp
Common Stock 		1,585,591
2012-03-08 3 XOMA XOMA Corp
Common Stock 		13,606,093
2012-03-05 2012-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,845 226,741 0.82 30.07 55,477 6,817,830
2012-03-05 2012-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,254 224,896 1.01 29.96 67,521 6,737,007
2012-03-05 2012-03-02 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,419 222,642 1.10 29.52 71,410 6,572,503
2012-03-05 2012-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 405 220,223 0.18 29.47 11,936 6,490,060
2012-03-05 2012-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 69,783 8,213,837 0.86 30.07 2,098,291 246,980,222
2012-03-05 2012-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 85,231 8,144,054 1.06 29.96 2,553,188 243,964,096
2012-03-05 2012-03-02 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 91,459 8,058,823 1.15 29.52 2,699,915 237,900,484
2012-03-05 2012-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 15,288 7,967,364 0.19 29.47 450,543 234,801,404
2012-03-05 2012-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 8,372 1,480,469 0.57 30.07 251,736 44,515,926
2012-03-05 2012-03-05 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 10,225 1,472,097 0.70 29.96 306,301 44,098,285
2012-03-05 2012-03-02 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 10,972 1,461,872 0.76 29.52 323,899 43,155,192
2012-03-05 2012-03-01 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,763 1,450,900 0.12 29.47 51,956 42,758,603
2012-02-29 2012-02-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,149 219,818 1.92 29.06 120,562 6,387,493
2012-02-29 2012-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,353 215,669 0.63 29.11 39,384 6,277,801
2012-02-29 2012-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 974 214,316 0.46 29.03 28,276 6,221,722
2012-02-29 2012-02-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 156,902 7,952,076 2.01 29.06 4,559,274 231,072,220
2012-02-29 2012-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 51,248 7,795,174 0.66 29.11 1,491,752 226,905,822
2012-02-29 2012-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 36,881 7,743,926 0.48 29.03 1,070,678 224,810,818
2012-02-29 2012-02-29 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 19,552 1,449,137 1.37 29.06 568,144 42,109,168
2012-02-29 2012-02-28 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,934 1,429,585 0.42 29.11 172,730 41,613,075
2012-02-29 2012-02-27 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,270 1,423,651 0.30 29.03 123,961 41,329,443
2012-02-23 2012-02-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,639 213,342 0.77 28.12 46,095 5,999,988
2012-02-23 2012-02-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 145 211,703 0.07 27.98 4,057 5,923,683
2012-02-23 2012-02-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,238 211,558 0.59 27.98 34,635 5,918,737
2012-02-23 2012-02-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 62,098 7,707,045 0.81 28.12 1,746,432 216,751,392
2012-02-23 2012-02-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,511 7,644,947 0.07 27.98 154,204 213,914,027
2012-02-23 2012-02-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 46,909 7,639,436 0.62 27.98 1,312,368 213,727,737
2012-02-23 2012-02-23 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7,477 1,419,381 0.53 28.12 210,282 39,918,387
2012-02-23 2012-02-22 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 638 1,411,904 0.05 27.98 17,852 39,506,627
2012-02-23 2012-02-21 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 5,217 1,411,266 0.37 27.98 145,955 39,482,848
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,419 210,320 1.16 29.85 72,219 6,279,062
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,460 207,901 1.20 29.61 72,842 6,156,073
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 10 205,441 0.00 28.96 290 5,950,085
2012-02-16 2012-02-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 849 205,431 0.41 28.88 24,517 5,932,272
2012-02-16 2012-02-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,475 204,582 0.73 28.44 41,945 5,817,698
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 91,543 7,592,527 1.22 29.85 2,732,998 226,673,375
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 93,088 7,500,984 1.26 29.61 2,756,392 222,108,637
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 349 7,407,896 0.00 28.96 10,108 214,551,188
2012-02-16 2012-02-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 32,125 7,407,547 0.44 28.88 927,680 213,909,216
2012-02-16 2012-02-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 55,804 7,375,422 0.76 28.44 1,586,898 209,734,875
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 10,838 1,406,049 0.78 29.85 323,566 41,977,312
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 11,021 1,395,211 0.80 29.61 326,338 41,313,035
2012-02-16 2012-02-16 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 41 1,384,190 0.00 28.96 1,187 40,089,603
2012-02-16 2012-02-15 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,944 1,384,149 0.29 28.88 113,892 39,970,348
2012-02-16 2012-02-14 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7,341 1,380,205 0.53 28.44 208,756 39,248,890
2012-02-14 2012-02-10 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 150,000 557,211 36.84 20.85 3,128,040 11,619,855
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 753 203,107 0.37 26.52 19,967 5,385,666
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 492 202,354 0.24 26.62 13,098 5,387,048
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,980 201,862 1.50 26.60 79,278 5,370,195
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 102 198,882 0.05 26.24 2,676 5,217,868
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,312 198,780 0.66 26.33 34,540 5,233,162
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 64 197,468 0.03 26.27 1,681 5,187,208
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 1,594 197,404 0.81 26.26 41,851 5,182,921
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,585 195,810 1.87 26.18 93,840 5,125,464
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 161 192,225 0.08 26.17 4,213 5,029,586
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 28,469 7,319,618 0.39 26.52 754,895 194,089,919
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 18,628 7,291,149 0.26 26.62 495,913 194,104,240
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 112,735 7,272,521 1.57 26.60 2,999,123 193,473,058
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 3,883 7,159,786 0.05 26.24 101,874 187,844,145
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 49,670 7,155,903 0.70 26.33 1,307,632 188,389,165
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,441 7,106,233 0.03 26.27 64,122 186,670,792
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 60,315 7,103,792 0.86 26.26 1,583,594 186,512,900
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 135,681 7,043,477 1.96 26.18 3,551,545 184,367,941
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 6,093 6,907,796 0.09 26.17 159,424 180,743,173
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 4,378 1,372,864 0.32 26.52 116,089 36,403,411
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 2,865 1,368,486 0.21 26.62 76,272 36,431,697
2012-02-10 2012-02-10 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 17,339 1,365,621 1.29 26.60 461,275 36,330,025
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 615 1,348,282 0.05 26.24 16,135 35,373,527
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 7,858 1,347,667 0.59 26.33 206,873 35,479,221
2012-02-10 2012-02-09 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 387 1,339,809 0.03 26.27 10,166 35,194,907
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 9,891 1,339,422 0.74 26.26 259,692 35,167,060
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 22,251 1,329,531 1.70 26.18 582,436 34,801,405
2012-02-10 2012-02-08 4 GHDX GENOMIC HEALTH INC
Common Stock 		P - Purchase 999 1,307,280 0.08 26.17 26,139 34,205,112
2012-02-03 2012-02-01 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		P - Purchase 23,172 116,454 24.84 17.00 393,924 1,979,718
2012-02-03 2012-02-01 4 RDEA Ardea Biosciences, Inc./DE
Common Stock 		P - Purchase 876,828 4,922,226 21.67 17.00 14,906,076 83,677,842
2012-01-31 2012-01-27 4 DDXS diaDexus, Inc.
Common Stock 		S - Sale -59,340 0 -100.00 0.22 -13,156
2012-01-26 2012-01-26 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 12,907 407,211 3.27 17.89 230,942 7,286,145
2012-01-26 2012-01-26 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 28,966 394,304 7.93 17.95 519,960 7,078,033
2012-01-26 2012-01-25 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 3,018 365,338 0.83 18.43 55,629 6,734,093
2012-01-26 2012-01-25 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 18,547 362,320 5.40 18.55 343,997 6,720,058
2012-01-26 2012-01-24 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 14,629 343,773 4.44 18.01 263,424 6,190,320
2012-01-26 2012-01-24 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 7,926 329,144 2.47 17.86 141,534 5,877,491
2012-01-26 2012-01-26 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,944 195,858 1.00 17.89 34,784 3,504,448
2012-01-26 2012-01-26 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 4,360 193,914 2.30 17.95 78,265 3,480,892
2012-01-26 2012-01-25 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 454 189,554 0.24 18.43 8,368 3,493,954
2012-01-26 2012-01-25 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 2,792 189,100 1.50 18.55 51,784 3,507,294
2012-01-26 2012-01-24 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 2,202 186,308 1.20 18.01 39,651 3,354,848
2012-01-26 2012-01-24 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,193 184,106 0.65 17.86 21,303 3,287,562
2012-01-26 2012-01-26 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 75,149 8,574,445 0.88 17.89 1,344,626 153,420,829
2012-01-26 2012-01-26 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 168,641 8,499,296 2.02 17.95 3,027,224 152,568,313
2012-01-26 2012-01-25 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 17,571 8,330,655 0.21 18.43 323,877 153,554,798
2012-01-26 2012-01-25 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 107,980 8,313,084 1.32 18.55 2,002,737 154,185,263
2012-01-26 2012-01-24 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 85,169 8,205,104 1.05 18.01 1,533,638 147,749,308
2012-01-26 2012-01-24 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 46,142 8,119,935 0.57 17.86 823,953 144,996,867
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 7,925 321,218 2.53 16.84 133,456 5,409,279
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 12,694 313,293 4.22 16.88 214,254 5,287,885
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 7,590 300,599 2.59 16.90 128,252 5,079,372
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		X - Other -16 0 -100.00 1.50 -24
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		X - Other -28 16 -63.64 1.25 -35 20
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		P - Purchase 16 44 57.14 1.50 24 66
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		X - Other 1,600 293,009 0.55 15.00 24,000 4,395,135
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		X - Other 2,800 291,409 0.97 15.00 42,000 4,371,135
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 12,041 288,609 4.35 16.44 197,940 4,744,386
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 31,115 276,568 12.68 16.41 510,585 4,538,370
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Call Option 		P - Purchase 28 28 1.25 35 35
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 426 245,453 0.17 15.81 6,735 3,880,391
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,795 245,027 0.74 16.07 28,843 3,937,241
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 3,839 243,232 1.60 16.07 61,686 3,908,300
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,201 182,913 0.66 16.84 20,225 3,080,237
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,923 181,712 1.07 16.88 32,457 3,067,008
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,149 179,789 0.64 16.90 19,415 3,037,985
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		X - Other -2 0 -100.00 1.50 -3
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		X - Other -5 2 -71.43 1.25 -6 2
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		P - Purchase 2 7 40.00 1.50 3 10
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		X - Other 200 178,640 0.11 15.00 3,000 2,679,600
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		X - Other 500 178,440 0.28 15.00 7,500 2,676,600
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 1,824 177,940 1.04 16.44 29,984 2,925,120
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 4,712 176,116 2.75 16.41 77,322 2,889,993
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Call Option 		P - Purchase 5 5 1.25 6 6
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 66 171,404 0.04 15.81 1,043 2,709,743
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 278 171,338 0.16 16.07 4,467 2,753,162
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 594 171,060 0.35 16.07 9,545 2,748,626
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 45,574 8,073,793 0.57 16.84 767,462 135,961,867
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 72,997 8,028,219 0.92 16.88 1,232,073 135,503,492
2012-01-23 2012-01-23 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 43,644 7,955,222 0.55 16.90 737,474 134,423,364
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		X - Other -87 0 -100.00 1.50 -130
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		X - Other -162 87 -65.06 1.25 -202 109
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Call Option 		P - Purchase 87 249 53.70 1.50 130 373
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		X - Other 8,700 7,911,578 0.11 15.00 130,500 118,673,670
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		X - Other 16,200 7,902,878 0.21 15.00 243,000 118,543,170
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 69,245 7,886,678 0.89 16.43 1,137,958 129,608,089
2012-01-23 2012-01-20 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 178,921 7,817,433 2.34 16.41 2,936,022 128,280,949
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Call Option 		P - Purchase 162 162 1.25 202 202
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 2,449 7,638,512 0.03 15.81 38,716 120,758,000
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 10,327 7,636,063 0.14 16.07 165,940 122,700,842
2012-01-23 2012-01-19 4 PCYC PHARMACYCLICS INC
Common Stock 		P - Purchase 22,081 7,625,736 0.29 16.07 354,802 122,531,851
2012-01-20 2012-01-19 4 DDXS diaDexus, Inc.
Common Stock 		S - Sale -20,000 59,340 -25.21 0.20 -4,000 11,868
2012-01-20 2012-01-18 4 DDXS diaDexus, Inc.
Common Stock 		S - Sale -118,800 79,340 -59.96 0.21 -25,233 16,852
2012-01-17 2012-01-13 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1,122 355,839 0.32 16.62 18,648 5,914,115
2012-01-17 2012-01-13 4 INCY INCYTE CORP
Common Stock 		P - Purchase 1,965 354,717 0.56 16.58 32,576 5,880,463
2012-01-17 2012-01-13 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,769 352,752 0.79 16.46 45,570 5,805,345
2012-01-17 2012-01-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 5,919 349,983 1.72 16.21 95,924 5,671,859
2012-01-17 2012-01-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 2,850 344,064 0.84 16.38 46,691 5,636,697
2012-01-17 2012-01-13 4 INCY INCYTE CORP
Common Stock 		P - Purchase 41,677 12,430,783 0.34 16.62 692,680 206,602,100
2012-01-17 2012-01-13 4 INCY INCYTE CORP
Common Stock 		P - Purchase 72,978 12,389,106 0.59 16.58 1,209,822 205,385,360
2012-01-17 2012-01-13 4 INCY INCYTE CORP
Common Stock 		P - Purchase 102,856 12,316,128 0.84 16.46 1,692,732 202,690,213
2012-01-17 2012-01-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 219,881 12,213,272 1.83 16.21 3,563,413 197,929,507
2012-01-17 2012-01-12 4 INCY INCYTE CORP
Common Stock 		P - Purchase 105,847 11,993,391 0.89 16.38 1,734,060 196,484,127
2012-01-09 2012-01-05 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		A - Award 29,089 135,739 27.28 25.18 732,461 3,417,908
2012-01-09 2012-01-05 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		A - Award 1,077,225 5,077,676 26.93 25.18 27,124,526 127,855,882
2012-01-09 2012-01-05 4 GEVA SYNAGEVA BIOPHARMA CORP
Common Stock 		A - Award 187,576 1,736,065 12.11 25.18 4,723,164 43,714,117
2012-01-05 2012-01-03 4 RDEA Ardea Biosciences, Inc./DE
Stock Options (Right to Buy) 		A - Award 12,500 12,500
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		X - Other -355,143 0 -100.00
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		X - Other 355,143 15,131,223 2.40 6.25 2,219,644 94,570,144
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		X - Other -49,563 0 -100.00
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		X - Other 49,563 450,461 12.36 6.25 309,769 2,815,381
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		X - Other -68,006 0 -100.00
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		X - Other 68,006 539,130 14.43 6.25 425,038 3,369,562
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		X - Other -339,788 0 -100.00
2012-01-04 2011-12-30 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		X - Other 339,788 4,966,001 7.34 6.25 2,123,675 31,037,506
2012-01-03 2011-12-19 4 ADLR ADOLOR CORP
Common Stock 		U - Other -186,272 0 -100.00 4.25 -791,656
2012-01-03 2011-12-19 4 ADLR ADOLOR CORP
Common Stock 		U - Other -6,669,338 0 -100.00 4.25 -28,344,686
2012-01-03 2011-12-19 4 ADLR ADOLOR CORP
Common Stock 		U - Other -12,679 0 -100.00 4.25 -53,886
2012-01-03 2011-12-19 4 ADLR ADOLOR CORP
Common Stock 		U - Other -79,054 0 -100.00 4.25 -335,980
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Series A Convertible Preferred Stock 		J - Other 284,115 284,115
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Series A Convertible Preferred Stock 		J - Other -34,385 0 -100.00
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Series A Convertible Preferred Stock 		J - Other -249,730 0 -100.00
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		J - Other 355,143 355,143
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		J - Other -42,981 0 -100.00
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock Warrants (right to buy) 		J - Other -312,162 0 -100.00
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other 448,047 682,908 190.77
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other -45,090 0 -100.00
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other -49,807 0 -100.00
2006-04-28 2006-04-25 4 SGEN SEATTLE GENETICS INC /WA
Common Stock 		J - Other -353,150 0 -100.00
P
非衍生或衍生證券的公開市場或私下買入
S
非衍生或衍生證券的公開市場或私下賣出
A
公司向內部人員授予、獎勵或以其他方式獲取證券（例如股票期權）
C
衍生工具轉換
D
將證券賣出或轉讓回公司
F
使用從公司收到的證券的一部分來支付行使價或稅務負擔。
G
內部人士贈送或接收他人贈送公司股票
K
股權掉期和類似的避險交易
M
行使或轉換從公司獲得的衍生證券（例如期權）
V
內部人士透過Form 4自願報告的一筆交易
J
其他（附有交易描述的腳註）